Clinical trials: Sigmoid Diverticulosis
Diverticulitis, Acute Diverticulitis
Randomized Multicentric Trial to Evaluate a Free Diet With a Progressive Diet in the Treatment of Acute Diverticulitis (DIVERDIET)
Phase III trial is designed to demonstrate the non-inferiority of a free diet versus a progressive diet in the treatment of acute diverticulitis (AD) without complications.
- Conditions
- Diverticulitis, Acute Diverticulitis, Diverticulitis, Colonic, Uncomplicated Diverticular Disease
- Trial name
- NCT03496090
- Testing
- Free diet, Progressive diet
- Where
- Spain
- Volunteers
- 134 people
- Sponsor
- Hospital General Universitario Reina Sofía de Murcia
Colorectal Cancer, Colorectal Anastomosis
Single-Stapled Technique for Colorectal Anastomosis
The goal of this observational multicenter study is to evaluate the safety and feasibility of a single-stapled technique (SST) for colorectal anastomosis and to explore whether this technique is associated with a reduced rate of…
- Conditions
- Colorectal Cancer, Colorectal Anastomosis, Anastomotic Leakage, Diverticular Disease of Left Side of Colon
- Trial name
- SST (NCT07417358)
- Testing
- Single-stapled colorectal anastomosis, Double-stapled colorectal anastomosis
- Where
- 5 sites in Sweden
- Volunteers
- 500 people
- Sponsor
- Umeå University
Sigmoid Cancer, Sigmoid Diverticulosis
Comparison of Quality of Life and Functionnal Resultats After Sigmodectomy Between Diverticulitis and Cancer
The aim of this present study is to compare functional results and quality of life after sigmoidectomy for diverticulitis and sigmoid cancer.
- Trial name
- SIG-QOL (NCT04729283)
- Testing
- Sigmoidectomy
- Where
- 4 sites in France
- Volunteers
- 94 people
- Sponsor
- Nantes University Hospital
Sigmoid Diverticulosis, Sigmoid Diverticulitis
Feasibility, Safety and Outcome of Transrectal Hybrid-NOTES Anterior Resection
Natural orifice transluminal endoscopic surgery has become an important topic. NOTES access routes give the opportunity to reduce surgical access trauma leading to a more painless surgery and enhancing a fast postoperative…
- Conditions
- Sigmoid Diverticulosis, Sigmoid Diverticulitis, Colon Adenoma, Rectal Prolapse
- Trial name
- NCT01992406
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Cantonal Hospital, Baselland
Sigmoid Diverticulosis, Sigmoid Diverticulitis
Perfusion Evaluation by Real-time Fluorescence-based Enhanced Reality of Anastomosis
The aim of this study is to evaluate the ability of a ICG-fluorescence guidance complemented with enhanced reality to correctly document intestinal pre-anastomotic perfusion and to validate the accuracy of this technique with…
- Conditions
- Sigmoid Diverticulosis, Sigmoid Diverticulitis, Colorectal Malignancy
- Trial name
- PERFECT (NCT02626091)
- Testing
- Left-sided colonic resection
- Where
- France
- Volunteers
- 27 people
- Sponsor
- IHU Strasbourg
Diverticulum, Colon, Sigmoid
LASER Trial. LAparoscopic Elective Sigmoid Resection Following divERticulitis - a Multicenter, Prospective, Randomized Clinical Trial
The purpose of this study is to find out whether elective sigmoid resection will improve quality of life compared to conservative treatment with lifestyle guidance and fiber supplement in patients with a recurrent or complicated…
- Trial name
- LASER (NCT02174926)
- Testing
- Elective laparoscopic sigmoid resection, Conservative treatment
- Where
- 11 sites in Finland
- Volunteers
- 133 people
- Sponsor
- Helsinki University Central Hospital
Sigmoid Diverticulosis, Colorectal Surgery
Impact of Socioeconomic and Territorial Inequalities on Surgical Management of Sigmoid Diverticulitis
Sigmoid diverticulitis (SD) is a common pathology characterized by inflammation/infection of a diverticulum in the sigmoid colon.
- Trial name
- EDIVERTICULITE (NCT06200857)
- Where
- France
- Volunteers
- 6,800 people
- Sponsor
- University Hospital, Caen
Sigmoid Diverticulitis (Hinchey I and II), Sigmoid Diverticulosis With Two or More Attacks of Diverticulitis
Laparoscopic Transvaginal Hybrid Anterior Resection: a Prospective Data Collection
Transvaginal hybrid procedures are of interest as an available NOTES-Procedure for the clinical routine. Few authors have demonstrated the feasibility and safety of such procedures (e.g.
- Trial name
- NCT01043731
- Testing
- Laparoscopic transvaginal hybrid anterior resection
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- Cantonal Hospital of St. Gallen
Diverticulitis
Laparoscopic Versus Open Sigmoid Colectomy for Diverticular Disease
Aim: This is a prospective, randomized comparison of traditional open (OS) and laparoscopic sigmoidectomy (LS) in patients with complicated diverticular disease.
- Trial name
- NCT00453830
- Testing
- laparoscopic sigmoid resection
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Geneva
Acute Diverticulitis, Diverticular Diseases
Towards a Tailored Approach for Patients With Acute Diverticulitis and Abscess Formation. A Multicenter Cohort Analysis
It is estimated that approximately 15% to 20% of the subjects with sigmoid diverticulosis will develop acute diverticulitis, with diverticular abscess as the most common complication of sigmoid diverticulitis.
- Conditions
- Acute Diverticulitis, Diverticular Diseases, Diverticulitis of Sigmoid, Acute Diverticular Perforation
- Trial name
- DivAbsc2023 (NCT06109506)
- Testing
- Conservative treatment with antibiotics and eventual percutaneous image-guided drainage of the abscess
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- University of Cagliari
Outcome
Treatment in Right Colon Diverticulitis Patients
The right colon diverticula, unlike those in the left colon, contain all layers of the colon and is called the true diverticulum. Perforation is observed less frequently due to its full thickness.
- Trial name
- NCT04746326
- Testing
- Failure conservative treatment, Surgery, Conservative treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Tepecik Training and Research Hospital
Diverticulitis, Colonic, Acute Disease
Study to Evaluate the Duration of Treatment With Ertapenem in Acute Attacks of Sigmoid Diverticulitis
The purpose of this study is to compare the efficacy (by assessing the clinical success of treatment) of intravenous antibiotic therapy with ertapenem in patients with acute attacks of sigmoid diverticulitis for 4 vs. 7 days.
- Trial name
- NCT00097734
- Testing
- ertapenem
- Where
- Germany
- Volunteers
- 540 people
- Sponsor
- Klinikum Hanover-Siloah Hospital
Diverticulitis, Diverticulitis of Sigmoid
Clinical Trial With MBK-01, Intestinal Microbiota Capsules, for the Treatment of Patients With Recurrent Diverticulitis
Patients with diverticulitis experience a prolonged course of the disease and report a variety of physical, psychological and social symptoms, which highly impacts in their quality of life.
- Trial name
- NCT06687382
- Testing
- MBK-01
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- Mikrobiomik Healthcare Company S.L.
Diverticular Disease of Left Side of Colon
Quality of Life (QOL) After Elective Sigmoidectomy for Diverticular Diseases (DIVERTI)
Acute diverticulitis of the left colon is among the most common abdominal disorders. To date, both conservative therapy in uncomplicated stages and emergency surgery in perforated disease with peritonitis are consensual.
- Trial name
- DIVERTI-QDV (NCT04730765)
- Testing
- left elective colectomy (Surgical Experimental Group), antibiotic therapy (medical Control Group)
- Volunteers
- 220 people
- Sponsor
- University Hospital, Caen
Diverticulitis, Diverticulitis Colon
Management and Evolution of Acute Diverticulitis With Pericolic Free Gas
The severity of diverticulitis is usually graded with the use of modified Hinchey Criteria. However, there is a condition often seen in the CT scan that is not included in this classification itself; 1-2 pericolic bubbles but no…
- Conditions
- Diverticulitis, Diverticulitis Colon, Diverticulitis; Perforation, Bowel, Diverticulitis of Sigmoid
- Trial name
- ADiFas (NCT04311385)
- Testing
- CT imaging
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Hospital Central de la Defensa Gómez Ulla