Clinical trials: Silodosin
Ureteral Calculi, Kidney Stones
Study of Silodosin to Facilitate Passage of Urinary Stones
The purpose of this study is to assess if patients treated with silodosin will have a higher spontaneous passage rate of their ureteral stone than those treated with placebo.
- Conditions
- Ureteral Calculi, Kidney Stones, Urolithiasis
- Trial name
- NCT01144949
- Testing
- silodosin
- Where
- 27 sites in United States
- Volunteers
- 239 people
- Sponsor
- Watson Pharmaceuticals
Abacterial Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Use of Silodosin to Treat Moderate to Severe Abacterial Chronic Prostatitis/Chronic Pelvic Pain Syndrome.
The primary objective is to compare the efficacy of silodosin 4 and 8 mg once daily with placebo in the treatment of subjects with moderate to severe abacterial chronic prostatitis/chronic pelvic pain syndrome during a 12 week…
- Trial name
- NCT00740779
- Testing
- Silodosin 8 mg, Silodosin 4 mg
- Where
- 22 sites in United States
- Volunteers
- 153 people
- Sponsor
- Watson Pharmaceuticals
Ureteric Stone of Lower Third of Ureter
Medical Stone Expulsive Therapy for Acutely Obstructed Ureteric Calculi
As a first treatment option for small-size ureteric stones, α-blockers are now being used for medical expulsive therapy (MET) instead of invasive procedures.
- Trial name
- NCT05977647
- Testing
- Tamsulosin Oral Capsule
- Where
- Pakistan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Getz Pharma
Benign Prostate Obstruction (BPO), Lower Urinary Tract Symptom
Clinical Outcomes and Ejaculatory Function in BPO Patients Treated With Silodosin
This observational study aims to evaluate the relationship between silodosin-induced anejaculation and clinical outcomes in male patients with benign prostatic obstruction (BPO).
- Conditions
- Benign Prostate Obstruction (BPO), Lower Urinary Tract Symptom, Ejaculatory Dysfunction, Anejaculation
- Trial name
- NCT06989515
- Volunteers
- 100 people
- Sponsor
- Marmara University
Ureteral Stone
Efficacy and Safety of Silodosin in the Treatment of Natural Expulsion in Patients With Ureteral Stones
A lower ureteral calculus, which measures 5 millimeters and less, may be easily expelled by symptomatic therapy. Actually, it has about a 50% chance of successful expulsion.
- Trial name
- STONE (NCT01533389)
- Testing
- Silodosin
- Where
- 5 sites in South Korea
- Volunteers
- 114 people
- Sponsor
- JW Pharmaceutical
Stone Ureter, Stone, Kidney
Silodosin in Facilitating Flexible Uretroscopy
This study aims to provide robust evidence on whether a specific, potent pre-operative medication (silodosin) can make the critical step of ureteral access (UAS placement after dilation) easier and safer during f-URS for kidney…
- Trial name
- NCT07068087
- Testing
- Preoperative sioldosin to facilitate ureteric access sheath insertion in RIRS
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Ain Shams University
Nocturia, Prostatic Hyperplasia
A Study of Silodosin 8 mg Daily for the Treatment of Nocturia in Men With Benign Prostatic Hyperplasia
Silodosin is compared to placebo to determine if it is safe and effective for the treatment of nighttime urination (nocturia) in men with BPH
- Trial name
- NCT00793819
- Testing
- silodosin
- Where
- 27 sites in United States
- Volunteers
- 215 people
- Sponsor
- Watson Pharmaceuticals
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Silodosin vs Tamsulosin for LUTS Due to BPH: A Randomized Crossover Trial
The goal of this randomized crossover clinical trial is to compare the efficacy and safety of Silodosin versus Tamsulosin in patients with moderate to severe lower urinary tract symptoms due to Benign Prostatic Hyperplasia.
- Trial name
- NCT07467343
- Testing
- Silodosin, Tamsulosin
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Benign Prostatic Hyperplasia, Silodosin
Pupil Size and Choroidal Thickness Changes With Tamsulosin vs. Silodosin in Benign Prostatic Hyperplasia Patients
Benign prostatic hyperplasia (BPH) is a common disease in men and is treated with alpha-blockers, particularly tamsulosin and silodosin.
- Conditions
- Benign Prostatic Hyperplasia, Silodosin, Tamsulosin, Choroid
- Trial name
- NCT07743060
- Testing
- tamsulosin 0.4mg, Silodosin 8 mg
- Volunteers
- 40 people
- Sponsor
- Mohsen Pourazizi
Prostatic Hyperplasia
The Additive Value of Pyridostigmine to Silodosin in Acute Urinary Retention
Acute urine retention, AUR, is often considered the most serious consequence of aging men with progressive benign prostatic hyperplasia (BPH). AUR is defined as the sudden and painful inability to void freely.
- Trial name
- NCT06319469
- Testing
- silodosin 8 mg capsule and the pyridostigmine bromide 60 mg tablet, silodosin 8 mg capsule
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Beni-Suef University
Multiple Sclerosis, Lower Urinary Track Symptoms
Silodosin for Urinary Symptoms in Female Patients With Multiple Sclerosis
The goal of this clinical trial is to learn if silodosin works to treat lower urinary tract symptoms (LUTS) in female patients with multiple sclerosis (MS). It will also learn about the effect of the drug on voiding parameters.
- Trial name
- NCT07614321
- Testing
- Silodosin 8 mg
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Atlantic Health System
Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
The Efficacy and Safety of Silodosin in the Treatment of Benign Prostatic Hyperplasia
Objective: To evaluate the efficacy and safety of Silodosin Capsules in the treatment of Benign Prostatic Hyperplasia (BPH) with Lower Urinary Tract Symptoms (LUTS) compared with Tamsulosin Hydrochloride Sustained Release…
- Trial name
- NCT05551221
- Testing
- Silodosin Capsules, Tamsulosin
- Where
- 8 sites in China
- Volunteers
- 110 people
- Sponsor
- Xintian Pharmaceutical
Human Trichinellosis
Efficacy and Safety of Silodosin in the Treatment of Lower Urinary Tract Symptoms in Taiwanese Population.
To evaluate the therapeutic effects and safety of silodosin in the patients of acute brain injury with lower urinary tract symptoms.
- Trial name
- NCT06332235
- Testing
- Silodosin 8 mg
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Benign Prostatic Hyperplasia
Evaluation of the Efficacy and Safety of Silodosin in the Treatment of the Signs and Symptoms of BPH
A new drug for the treatment of benign prostatic hyperplasia is compared with placebo and tamsulosin (a drug belonging to the same therapeutic class) for to determine if it is safe and effective (the first phase of the study…
- Trial name
- NCT00359905
- Testing
- Silodosin, Tamsulosin
- Where
- United Kingdom
- Volunteers
- 1,228 people
- Sponsor
- RECORDATI GROUP
Premature (Early) Ejaculation
On-demand Silodosin 4mg vs Dapoxetine 60mg in Treatment of Primary Premature Ejaculation
Both Silodosin 4 mg and Dapoxetine 60 mg significantly improved IELT and sexual function scores in primary PE patients. However, Silodosin exhibited a more favorable tolerability profile with fewer side effects, making it a…
- Trial name
- NCT07081659
- Testing
- sildosin 4mg, dapoxetine 60mg
- Where
- Egypt
- Volunteers
- 95 people
- Sponsor
- Benha University
Nocturia, Benign Prostatic Hyperplasia
Efficacy and Safety of Silodosin on Nocturia for Patients With Benign Prostatic Hyperplasia
The objective of this study is to determine safety and efficacy of silodosin, which is a treatment for benign prostatic hyperplasia with high selectivity to α1A-receptor, on patients with benign prostatic hyperplasia accompanied…
- Trial name
- BPH (NCT02106182)
- Testing
- Silodosin, Laboratory tests, 3-days voiding diary
- Where
- 6 sites in South Korea
- Volunteers
- 135 people
- Sponsor
- JW Pharmaceutical
Tamsulosin, Silodosin
Comparison of Silodosin and Tamsulosin for Medical Expulsive Therapy in Patients With Ureteral Stones
This study compares the effectiveness and side effect profiles of Tamsulosin and Silodosin in medical expulsive therapy (MET) for ureteric stones.
- Conditions
- Tamsulosin, Silodosin, Medical Expulsive Therapy
- Trial name
- NCT06999135
- Testing
- Silodosin
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Fatima Jinnah Medical University
Lower Ureteral Stones
Comparative Study for Medical Therapy for Lower Ureteral Stones
The goal of this clinical trial is to compare the efficacy and adverse effects of different drugs as a medical expulsive therapy for lower ureteral stones.
- Trial name
- NCT06707181
- Testing
- • The study will include 180 randomly selected patients who met inclusion criteria were randomized into four groups: silodosin 8 mg (Group A), tamsulosin 0.4 mg (Group B), silodosin 8 mg plus tadalaf
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Beni-Suef University
Benign Prostatic Hypertrophy
Safety and Efficacy of QD Versus BID Silodosin With Lower Urinary Tract Symptoms Suggestive of BPH
Korea has newly adopted 8mg Silodosin once daily. Against these backdrops, this clinical study is designed to demonstrate that the newly adopted dose is not inferior to the existing dose in its efficacy and safety.
- Trial name
- NCT01260129
- Testing
- Silodosin
- Where
- 14 sites in South Korea
- Volunteers
- 424 people
- Sponsor
- JW Pharmaceutical
Lower Ureteric Stones, Medical Expulsive Therapy
Silodosin, Tadalafil Alone vs. Silodosin Plus Tadalafil as MET for Lower Ureteric Stones
This study will compare the efficacy of silodosin, tadalafil versus silodosin plus tadalafil as Medical Expulsive Therapy (MET) for lower ureteric stones.
- Conditions
- Lower Ureteric Stones, Medical Expulsive Therapy, Tadalafil, Silodosin
- Trial name
- NCT05789732
- Testing
- Silodosin, Tadalafil, Silodosin and Tadalafil
- Where
- Egypt
- Volunteers
- 168 people
- Sponsor
- Benha University