Clinical trials: Simvastatin Multiple Sclerosis
Simvastatin Multiple Sclerosis
Role of Simvastatin in Relapsing-Remitting Multiple Sclerosis
The purpose of the clinical trial is to test how Simvastatin (80mg/day) may decrease attacks and progression of disease in patients with multiple sclerosis under disease modifying therapy (DMTs)
- Trial name
- NCT04178980
- Testing
- Simvastatin in relapsing remitting multiple sclerosis
- Volunteers
- 60 people
- Sponsor
- Assiut University
Relapsing Remitting Multiple Sclerosis
Simvastatin in Relapsing Remitting Multiple Sclerosis (RRMS) Patients Using Avonex Compared to Placebo
Patient with relapsing remitting multiple sclerosis taking avonex are included in this double blind randomized control trial. Simvastatin is compared to placebo.
- Trial name
- irmsrct (NCT00668343)
- Testing
- simvastatin
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Tehran University of Medical Sciences
Multiple Sclerosis
Simvastatin as an Add-on Treatment to Interferon-beta-1a for the Treatment of Relapsing-Remitting Multiple Sclerosis
This study is to find out if there is any benefit to adding Simvastatin to Interferon-beta-1a in patients with Multiple Sclerosis.
- Trial name
- SIMCOMBIN (NCT00492765)
- Testing
- Interferon-beta-1a, Simvastatin
- Where
- Denmark
- Volunteers
- 380 people
- Sponsor
- Biogen
Relapsing Remitting Multiple Sclerosis
Simvastatin as an add-on Treatment to Copaxone for the Treatment of Relapsing Multiple Sclerosis
A Double Blind, Randomised, Placebo Controlled Study Investigating Simvastatin as an add-on Treatment to Copaxone for the Treatment of Relapsing Multiple Sclerosis in patients treated with Copaxone for at least 3 months
- Trial name
- NCT00429442
- Testing
- Simvastatin
- Where
- Denmark
- Sponsor
- Anna Tsakiri
Relapsing Remitting Multiple Sclerosis
A Safety Study of Combination Treatment With Avonex and Zocor in Relapsing Remitting Multiple Sclerosis
The purpose of this study is to determine if using Avonex in combination with Zocor is a safe and effective therapy for subjects with relapsing remitting multiple sclerosis.
- Trial name
- NCT00242268
- Testing
- Simvastatin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Alabama Neurology Associates, PC
Optic Neuritis, Multiple Sclerosis
Simvastatin Treatment of Patients With Acute Optic Neuritis
The purpose of this study is to investigate if the simvastatin treatment improve the visual function after 3 months of the inclusion to this project and if the simvastatin influences the results on cerebral MRI after 3 and 6…
- Trial name
- NCT00261326
- Testing
- simvastatin
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Secondary Progressive Multiple Sclerosis
Investigation of Simvastatin in Secondary Progressive Multiple Sclerosis
To determine whether simvastatin at a dose of 80mg can reduce the rate of whole brain atrophy, as measured by MRI, over a 2-year time-period when compared to placebo.
- Trial name
- MS-STAT (NCT00647348)
- Testing
- Simvastatin
- Where
- 3 sites in United Kingdom
- Volunteers
- 140 people
- Sponsor
- Imperial College London
Secondary Progressive Multiple Sclerosis
Simvastatin in Secondary Progressive Multiple Sclerosis
Multiple sclerosis (MS) is a neurological condition which is a common cause of disability in young people. It is thought to be an autoimmune condition, where the body's immune system begins to attack itself.
- Trial name
- MS-OPT (NCT03896217)
- Testing
- Simvastatin
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University College, London
Secondary Progressive Multiple Sclerosis (SPMS)
Multiple Sclerosis-Simvastatin Trial 2
Multiple Sclerosis (MS) is a progressive neurological disorder of the brain and spinal cord. It affects approximately 120,000 people in the United Kingdom and 2.5 million people globally.
- Trial name
- MS-STAT2 (NCT03387670)
- Testing
- Simvastatin
- Where
- 31 sites in United Kingdom
- Volunteers
- 964 people
- Sponsor
- University College, London
Lymphangioleiomyomatosis, Tuberous Sclerosis Complex
Safety of Simvastatin in LAM and TSC
The purpose of this research study is to see if simvastatin can be taken safely in patients with either LAM or TSC, who are already being treated with everolimus or sirolimus.
- Trial name
- SOS (NCT02061397)
- Testing
- Simvastatin, Sirolimus Oral Product, Everolimus Oral Product
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pennsylvania
Multiple Sclerosis
EARLY IFNB-1a and Simvastatin Combination Therapy in Clinically Isolated Syndrome Suggestive of Multiple Sclerosis
The purpose of this study is to determine the safety, tolerability and efficacy of a combination therapy interferon beta-1a(Avonex) plus simvastatin (Zocor) vs.
- Trial name
- NCT00146068
- Testing
- Avonex/Zocor
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of North Carolina