Clinical trials: Single Embryo Transfer/Double Embryo Transfer
Infertility, Female, Infertility
Phase II Clinical Trial to Evaluate the Ongoing Pregnancy Rate With OXO-001 in IVF/ICSI With Donor Oocytes.
The main objective of this clinical research trial is to test the efficacy of OXO-001 in a daily oral administration increasing the pregnancy rate in IVF/ICSI by preparing the uterus to receive the embryo.
- Trial name
- OXOART2 (NCT05076032)
- Testing
- OXO-001
- Where
- 28 sites in Czechia, Poland and 1 more
- Volunteers
- 408 people
- Sponsor
- OXOLIFE
Infertility
Subcutaneous Progesterone in Frozen- Thawed Single Euploid Blastocyst Transfer.
This is a multicenter, randomized, double-blind, double-dummy, active-controlled, non-inferiority clinical study in women aged 35 to 42 years.
- Trial name
- PROGRESS (NCT04549116)
- Testing
- Progesterone-IBSA Injectable Solution, Progesterone Vaginal Gel with Applicator
- Where
- 24 sites in United States
- Volunteers
- 688 people
- Sponsor
- IBSA Institut Biochimique SA
Infertility
Screening of Low Responders for Aneuploidy to Improve Reproductive Efficiency
The purpose of this study is to assess the impact of Comprehensive Chromosome Screening(CCS) on patients with low ovarian reserve in an effort to improve success during in vitro fertilization and decrease the time to successful…
- Trial name
- Solaire (NCT01977144)
- Testing
- Comprehensive Chromosomal Screening
- Where
- United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Infertility
Frozen Embryo Transfer in PCOS Patients
Polycystic ovarian syndrome (PCOS) is condition characterized by being complex, familial and polygenetic metabolic condition with heterogeneous involvement of several genes in the hypothalamic-pituitary-gonadal axis.
- Trial name
- NCT05854810
- Testing
- fertilized embryo Insertion
- Where
- Egypt
- Volunteers
- 271 people
- Sponsor
- Zagazig University
Infertility, Oocyte Recipient
Single Embryo Transfer vs. Double Embryo Transfer in an Oocyte Donation Programme
Experimental study to assess the efficacy of single embryo transfer (SET) with respect to double embryo transfer (DET) in an oocyte donation programme, 160 recipients will be randomized in two groups
- Conditions
- Infertility, Oocyte Recipient, Single Embryo Transfer/Double Embryo Transfer, Cumulative Pregnancy Rate
- Trial name
- NCT01228474
- Testing
- Select the Number of embryos to transfer
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- Fundacion Dexeus
Infertility
Single Embryo Transfer Versus Double Embryo Transfer
The aim of this project is to study the best number (1 or 2)and day (3 vs 5)of embryo transfer in good prognosis patient.
- Trial name
- NCT00814398
- Testing
- Double Embryo Transfer (DET), Single Embryo Transfer (SET)
- Where
- Spain
- Volunteers
- 199 people
- Sponsor
- Vida Recoletas Sevilla
Infertility, Pregnancy, Multiple
eSET Plus Single Embryo Cryotransfer vs Double Embryo Transfer
The purpose of this study is to determine whether a policy of elective single embryo transfer (eSET) plus single embryo cryotransfer is as effective as a double embryo transfer in terms of clinical pregnancy rate
- Trial name
- eSET (NCT01909570)
- Testing
- Elective single embryo transfer, Double embryo transfer
- Where
- Spain
- Volunteers
- 194 people
- Sponsor
- University Hospital Virgen de las Nieves
Infertility
OBE001 Phase 2 Dose-finding Study Versus Placebo in Women Undergoing Embryo Transfer in the Context of IVF-ICSI
The primary objective of this study is to assess the increase in clinical pregnancy rate after administration of a range of single oral doses of OBE001, an oral oxytocin antagonist, compared to placebo.
- Trial name
- IMPLANT (NCT02310802)
- Testing
- OBE001 dose 1, OBE001 dose 2, OBE001 dose 3
- Where
- 18 sites in Belgium, Czechia and 4 more
- Volunteers
- 247 people
- Sponsor
- ObsEva SA
Infertility
What Embryoselection for What Chance of Success ? EmbryoSelect Study
The aim of the research is to evaluate the results of the first in vitro fertilization (IVF) attempt according to the type of embryo culture.
- Trial name
- EmbryoSelect (NCT04484181)
- Testing
- Embryo culture in time lapse technology (TLT), Embryo culture in conventional incubator
- Where
- 2 sites in France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Bordeaux
in Vitro Fertilization, Single Embryo Transfer
eSET or eDET Associated to PGT in IVF
In vitro fertilization (IVF) techniques have been improving performance recently and, nowadays, provide a live birth rate of around 25%.
- Conditions
- in Vitro Fertilization, Single Embryo Transfer, Preimplantation Genetic Diagnosis, Pregnancy
- Trial name
- SetDetPgt (NCT03758833)
- Testing
- preimplantation genetic test of embryo by new generation sequencing (NGS), Single embryo transfer, Double embryo tranfer
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo General Hospital
Amyotrophic Lateral Sclerosis
GM604 Phase 2A Randomized Double-blind Placebo Controlled Pilot Trial in Amyotrophic Lateral Disease (ALS)
GM604 is an endogenous human embryonic stage neural regulatory and signaling peptide that controls the development, monitoring and correction of the human nervous system.
- Trial name
- GALS (NCT01854294)
- Testing
- GM604
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Genervon Biopharmaceuticals, LLC
Infertility
Double Stimulation Followed by a Fresh Embryo Transfer
The major goal of controlled ovarian stimulation (COS) is to increase the number of oocytes harvested in order to result in the generation of a higher number of available embryos, extended embryo culture, embryo selection and…
- Trial name
- DUO_STIM_FRESH (NCT04446845)
- Testing
- Double Stimulation (Elonva+rFSH) in luteal /follicular phase, Conventional Stimulation (Elonva+rFSH) in follicular phase
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Fundación Santiago Dexeus Font
Infertility
Single Embryo Transfer of a Euploid Embryo Versus Double Embryo Transfer
This study seeks to compare the pregnancy and delivery rates of patients who undergo a single embryo transfer, when the embryo has been tested and determined to be chromosomally normal, with pregnancy and delivery rates of…
- Trial name
- NCT01408433
- Testing
- Single Embryo Transfer, Double embryo transfer
- Where
- 2 sites in United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Infertility
Phase 3 Placebo Controlled Study of Nolasiban to Improve Pregnancy Rates in Women Undergoing IVF/ICSI
The primary objective of this study is to confirm the efficacy of a single oral 900mg dose of nolasiban to increase the ongoing clinical pregnancy rate at 10 weeks post embryo transfer (ET) day.
- Trial name
- IMPLANT2 (NCT03081208)
- Testing
- Nolasiban 900mg
- Where
- 43 sites in Belgium, Czechia and 7 more
- Volunteers
- 810 people
- Sponsor
- ObsEva SA
Decision Making, Infertility, Female
Oocyte Recipient's Decision in the Number of Embryos to be Transferred
Multiple pregnancies are considered an ART complication. The only effective way to reduce its incidence is to transfer a single embryo. Nonetheless, there is some reluctance among the patients to accept this strategy.
- Conditions
- Decision Making, Infertility, Female, Counseling
- Trial name
- NCT03185715
- Testing
- Oral and written counselling
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fundacion Dexeus