Clinical trials: Single Embryo Transfer
Embryo Transfer
Study to Evaluate the Pharmacokinetics, Safety and Tolerability of GSK557296 in Healthy Women Volunteers After Single and Repeat Dosing
GSK557296 is being studied in women for the indication of enhanced embryo and or blastocyst implantation in women undergoing IVF treatment. This study will be the first dosing experience with this compound in women.
- Trial name
- NCT01669083
- Testing
- GSK557296 10 mg, GSK557296 150 mg, GSK557296 dose 3
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pregnancy
Idealizing Pregnancy Outcome With Single Blastocyst Transfer in a FET Cycle
Single embryo transfer (SET) has been advocated as a means of reducing the risk of multiple pregnancies, but has meant a reduction in pregnancy risk per embryo transfer.
- Trial name
- NCT01987856
- Testing
- Blastocyst morphology
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Antalya IVF
Infertility, Oocyte Recipient
Single Embryo Transfer vs. Double Embryo Transfer in an Oocyte Donation Programme
Experimental study to assess the efficacy of single embryo transfer (SET) with respect to double embryo transfer (DET) in an oocyte donation programme, 160 recipients will be randomized in two groups
- Conditions
- Infertility, Oocyte Recipient, Single Embryo Transfer/Double Embryo Transfer, Cumulative Pregnancy Rate
- Trial name
- NCT01228474
- Testing
- Select the Number of embryos to transfer
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- Fundacion Dexeus
Infertility (IVF Patients), Clinical Pregnancy After Single Embryo Transfer
Correlation Of Clinical Outcomes After Transfer Of Good-Quality Morphology Embryos In Patients With A Favorable Prognosis And Non-Invasive Preimplantation Genetic Testing For Aneuploidy (NiPGT-A) Results
Non-invasive preimplantation genetic testing for aneuploidy (NiPGT-A) is an emerging approach that analyzes embryonic cell-free DNA (cfDNA) released into the spent culture medium (SCM) to assess chromosomal status without…
- Conditions
- Infertility (IVF Patients), Clinical Pregnancy After Single Embryo Transfer, Embryo Diagnosis and Selection
- Trial name
- NCT07700602
- Where
- Vietnam
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
Infertility
Single Embryo Transfer Versus Double Embryo Transfer
The aim of this project is to study the best number (1 or 2)and day (3 vs 5)of embryo transfer in good prognosis patient.
- Trial name
- NCT00814398
- Testing
- Double Embryo Transfer (DET), Single Embryo Transfer (SET)
- Where
- Spain
- Volunteers
- 199 people
- Sponsor
- Vida Recoletas Sevilla
Clinical Pregnancy, Live Birth
Efficacy Study of Segmentation of PGD Treatment
A single centre observational study into the segmentation of preimplantation genetic diagnosis (PGD) treatment by comparing cumulative pregnancy rates following cryopreservation of all genetically transferable embryos after PGD…
- Trial name
- NCT02133950
- Testing
- elective cryopreservation of available embryos after PGD, PGD and elective fresh embryo transfer plus cryopreservation of supernumerary available embryos after PGD
- Where
- Belgium
- Volunteers
- 252 people
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility (IVF Patients), Infertility
Standardization of Variable Conditions of Embryo Transfer Into the Uterine Cavity in the Procedure of Medically Assisted Procreation in Humans
The EFECT study is a clinical trial designed to determine whether improving the consistency of embryo transfer procedures can increase pregnancy success in patients undergoing frozen embryo transfer (cryoET).
- Conditions
- Infertility (IVF Patients), Infertility, ART
- Trial name
- EFECT (NCT07396181)
- Testing
- Embryocase, Embryopass, Embryocase+Embryopass
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Przychodnia Lekarska nOvum Katarzyna Kozioł, Piotr Lewandowski sp.k.
DNA Methylation
Preimplantation DNA Methylation Test (PIMT) in ART
The purpose of this clinical trial is to determine the safety and effect of methylation level of DNA methylation in embryos on the outcome of assisted reproductive technology (ART) during blastocyst embryo screening.
- Trial name
- NCT03642574
- Testing
- CNV
- Where
- China
- Volunteers
- 182 people
- Sponsor
- Chen Zi-Jiang
Infertility
Efficacy of Embryo Transfer Procedure Guided by Transvaginal Ultrasound Versus Abdominal Ultrasound in Oocytes Recipients
The objective of this study is to evaluate the efficacy of embryo transfer procedure guided by transvaginal ultrasound versus abdominal ultrasound in recipients of oocytes as well as the advantages and disadvantages of the new…
- Trial name
- NCT01137461
- Testing
- ultrasound-guided embryo transfer
- Where
- Spain
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Fundació Privada Eugin
Infertility
A Comparison of Ongoing Pregnancy Rate Between Cleavage Stage and Early Compacting Embryo Transfer at 66±2 Hours After ICSI Using Single Step Culture Medium
A comparison of ongoing pregnancy rate between cleavage stage and early compacting embryo transfer at 66±2 hours after ICSI using single step culture medium
- Trial name
- NCT02987075
- Testing
- Compacting embryo transferring, Non- compacting embryo transferring
- Where
- Vietnam
- Volunteers
- 430 people
- Sponsor
- Vietnam National University
Infertility, Female
GEnetic Testing in Elective Single Embryo Transfer (GETSET): A Randomized Clinical Trial
The GETSET trial is a prospective randomized trial designed to evaluate the clinical outcomes of incorporating preimplantation genetic testing for aneuploidies (PGT-A) in elective single embryo transfer in women between 35 and 40…
- Trial name
- GETSET (NCT06141135)
- Testing
- Preimplantation genetic testing for aneuploidy (PGTA)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Genomic Prediction Inc.
IVF, Frozen Embryo Transfer (FET)
Single Step Protocol and Multi-step Warming Protocol for Blastocyst FET
The multi-step thawing protocol with a reduction of non-permeable cryoprotectant concentrations to reduce osmotic shock caused by the rapid influx of water.
- Conditions
- IVF, Frozen Embryo Transfer (FET), Embryo Thawing Protocol
- Trial name
- ONESTEP (NCT07088640)
- Testing
- Single-step warming protocol by thawing solution only, Standard warming protocol
- Where
- Vietnam
- Volunteers
- 816 people
- Sponsor
- Mỹ Đức Hospital
Female Infertility
AI-Assisted Euploid Embryo Selection for Single-Blastocyst Transfer in Women of Advanced Maternal Age
This single-center prospective randomized controlled study will enroll 500 infertile women aged 35 years or older who meet the criteria for fresh day-5 single-blastocyst transfer.
- Trial name
- NCT07833345
- Testing
- AI-assisted morphological assessment combined with euploidy prediction using EmbryoInsights™ Plus, AI-assisted morphological assessment using EmbryoInsights™
- Where
- China
- Volunteers
- 500 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Infertility, Aneuploidy
Single Embryo TrAnsfeR of Euploid Embryo
The purpose of the current study is to evaluate the effect of preimplantation genetic screening (PGS) by next generation sequencing (NGS) compared to standard morphological assessment of embryos on pregnancy rates through a…
- Trial name
- STAR (NCT02268786)
- Testing
- Preimplantation Genetic Screening by NGS
- Where
- 38 sites in United States, Australia and 2 more
- Volunteers
- 661 people
- Sponsor
- Illumina, Inc.
Single Embryo Transfer, Embryo Implantation, Delayed
Deferred Embryo Transfer in an In Vitro Program With Single Embryo Transfer Policy
Single embryo transfer decreases the multiple pregnancy rate and its complications. However, studies are needed to help increase the effectiveness of this technique to increase its use, which undoubtedly improves the safety of…
- Conditions
- Single Embryo Transfer, Embryo Implantation, Delayed, Pregnancy Rate
- Trial name
- NCT05721495
- Testing
- freeze all strategy embryo transfer, fresh embryo transfer strategy
- Where
- Spain
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University Hospital Virgen de las Nieves
Primary Infertility
Endometrial Injury and Single Embryo Transfer
Endometrial injury increases clinical pregnancy rate in normoresponder patients undergoing long agonist protocol intracytoplasmic sperm injection cycles with single embryo transfer.
- Trial name
- NCT01851876
- Testing
- Endometrial injury
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Infertility, Female
Retrospective Cohort Observational Study to Evaluate the Effectiveness and Safety of Fresh or Frozen Embryo Transfer
A multicenter, retrospective cohort observational study to evaluate the effectiveness and safety of fresh or frozen embryo transfer after ovarian hyperstimulation (administration of rFSH or HP-hMG alone or co-administration of…
- Trial name
- NCT05130125
- Testing
- rFSH
- Where
- South Korea
- Volunteers
- 1,166 people
- Sponsor
- LG Chem
ART, IVF
Cardiometabolic Function in Offspring, Mother and Placenta After Assisted Reproductive Technology
The overall objective is to establish the first-of-its-kind longitudinal cohort of pregnant women, biological fathers/partners and offspring from pregnancies achieved by frozen embryo transfer (FET), fresh-embryo transfer (fresh…
- Conditions
- ART, IVF, Children, Only, Cardiovascular Disease Other
- Trial name
- COMPART (NCT06334003)
- Where
- 3 sites in Denmark
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Infertility, Pregnancy, Multiple
eSET Plus Single Embryo Cryotransfer vs Double Embryo Transfer
The purpose of this study is to determine whether a policy of elective single embryo transfer (eSET) plus single embryo cryotransfer is as effective as a double embryo transfer in terms of clinical pregnancy rate
- Trial name
- eSET (NCT01909570)
- Testing
- Elective single embryo transfer, Double embryo transfer
- Where
- Spain
- Volunteers
- 194 people
- Sponsor
- University Hospital Virgen de las Nieves
Infertility
OBE001 Phase 2 Dose-finding Study Versus Placebo in Women Undergoing Embryo Transfer in the Context of IVF-ICSI
The primary objective of this study is to assess the increase in clinical pregnancy rate after administration of a range of single oral doses of OBE001, an oral oxytocin antagonist, compared to placebo.
- Trial name
- IMPLANT (NCT02310802)
- Testing
- OBE001 dose 1, OBE001 dose 2, OBE001 dose 3
- Where
- 18 sites in Belgium, Czechia and 4 more
- Volunteers
- 247 people
- Sponsor
- ObsEva SA