Clinical trials: Single Muscle Fibers
Obesity
Effect of Aging & Obesity With Exercise Intervention
Obesity leads to a vicious circle that increases intramuscular fat, insulin resistance, promotes muscular dysfunction resulting in increased muscle fat accumulation.
- Trial name
- NCT03951857
- Testing
- Resistance exercise with a gym stick
- Where
- South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Mitochondrial Diseases
DNA QUANTIFICATION TECHNIQUE AS A INTERPRETATION TOOL IN MITOCHONDRIAL DISEASES
2622/5000 Mitochondrial diseases (MM) are the most common metabolic diseases. Since these pathologies are very heterogeneous in clinical terms, only the identification of mutations in nuclear genes or mitochondrial DNA confirms…
- Trial name
- NCT03216252
- Testing
- samples
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Mitochondrial Disease
Development of a New Technique for Quantifying Mitochondrial DNA in Single Muscle Fibers
Mitochondrial diseases (MDs) are the most common metabolic disorders. Due to their great clinical and genetic heterogeneity, their diagnosis relies exclusively on the identification of pathogenic variants in nuclear genes or in…
- Trial name
- DIGITAL_MITO (NCT07511608)
- Testing
- Quantification of Mitochondrial DNA Heteroplasmy and Copy Number by Digital PCR in Mitochondrial Diseases
- Where
- 3 sites in France
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Single Muscle Fibers
Lean Muscle Function
This pilot study is designed to determine the relationship between intra-myocellular lipids and muscle contractility in fibers from obese and non-obese older adults.
- Trial name
- LEAN (NCT01616498)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Wake Forest University