Clinical trials: Single Women
Rectocele; Female
Long-term Results of the Stapled Transanal Rectal Resection (STARR) Operation Proposed in the Treatment of a Rectocele
Rectal static disorders, including the rectocele, represent a frequent functional pathology which affects the quality of life of affected patients.
- Trial name
- STARRLOC (NCT05037422)
- Testing
- STARR surgery
- Where
- France
- Volunteers
- 77 people
- Sponsor
- University Hospital, Grenoble
Kidney Diseases
Shrunken Pore Syndrome: a Retrospective, Single Center, Cohort Study
To study the impact a difference in renal clearance of small and large molecules has on long-term survival.
- Trial name
- NCT04141072
- Testing
- Shrunken Pore Syndrome
- Where
- Sweden
- Volunteers
- 4,719 people
- Sponsor
- Henrik Bjursten
Stress Urinary Incontinence, Urinary Incontinence
Combined Non-ablative Er:YAG Laser and Magnetic Stimulation for Treatment of Female Urinary Incontinence
This single-arm pilot study aims to investigate the efficacy and safety of a combined non-ablative Erbium:Yttrium-Aluminium-Garnet (Er:YAG) laser and High Intensity Tesla magnetic Stimulation (HITS) treatment for female urinary…
- Trial name
- NCT06559423
- Testing
- non-ablative Er:YAG laser and high intensity Tesla magnetic stimulation (HITS)
- Where
- Slovenia
- Volunteers
- 25 people
- Sponsor
- Zdravstveni Zavod Štrumbelj
Autosomal Dominant Polycystic Kidney
To Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral AL01211 in Healthy Volunteers
The study is designed to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of Oral AL01211 in healthy volunteers
- Trial name
- NCT04908462
- Where
- Australia
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- AceLink Therapeutics, Inc.
Ectopic Pregnancy
Single-port Versus Multi-port Laparoscopic Surgery for Ectopic Pregnancy
This study aims to compare the effectiveness and Safety of Single-port Versus Multi-port Laparoscopic Surgery in the Treatment of Ectopic Pregnancy
- Trial name
- NCT05890066
- Testing
- single-port laparoscopy
- Volunteers
- 100 people
- Sponsor
- Hung Vuong Hospital
Healthy
A Study of LY3526318 in Healthy Women
The main purpose of this study is to learn more about how LY3526318 affects blood flow to the skin in healthy women. For each participant, the study will last up to 28 days and Part B will last up to 78 days, including screening…
- Trial name
- NCT04183283
- Testing
- LY3526318
- Where
- Belgium
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Stress Urinary Incontinence, Urgency Urinary Incontinence
A Study to Estimate the Efficacy and Safety of Solifenacin in Female With Stress Urinary Incontinence and Urgency Urinary Incontinence
This study is to investigate the effects of solifenacin on urgency urinary incontinence symptoms and incontinence quality-of-life (I-QoL) in female patients with clinically significant stress urinary incontinence accompanied by…
- Trial name
- NCT01505439
- Testing
- solifenacin
- Where
- 6 sites in South Korea
- Volunteers
- 311 people
- Sponsor
- Jeong Gu Lee
Chronic Kidney Disease, Heart Failure With Reduced Ejection Fraction (HFrEF)
Single and Twice-daily Dosing of Ramipril on Renal Function in Chronic Kidney Disease Patients With Reduced Ejection Fraction Heart Failure
This study compares the effects of once-daily versus twice-daily ramipril dosing on renal function in chronic kidney disease (CKD) patients with heart failure with reduced ejection fraction (HFrEF).
- Trial name
- NCT07259512
- Testing
- Ramipril
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- Evi Liliek Wulandari
Obesity, Pregnancy
Randomized Controlled Trial: Induction of Labour of Obese Women With Dinoprostone or Single Balloon Catheter
The purpose of this study is to compare the efficacy of single balloon foley catheters to dinoprostone for the induction of labour of obese women.
- Conditions
- Obesity, Pregnancy, Labor, Induced
- Trial name
- NCT01962831
- Testing
- Dinoprostone, Single balloon foley catheter
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Saskatchewan Health Authority - Regina Area
Cervix Cancer, Cadonilimab
Evaluation of AK104 (Cadonilimab) Combined with Chemotherapy for Recurrent or Metastatic Small Cell Neuroendocrine Carcinoma of the Cervix
The goal of this clinical trial is to evaluate the safety and effectiveness of AK104 (Cadonilimab) combined with chemotherapy (cisplatin or carboplatin, and etoposide) for the treatment of recurrent or metastatic small cell…
- Conditions
- Cervix Cancer, Cadonilimab, Small Cell Neuroendocrine Carcinoma of the Cervix
- Trial name
- NCT06810895
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Ding Ma
Neurogenic Bladder Disorder, Bladder Dysfunction
Urinary Artificial Sphincter in Children
Retrospective monocentric study of the outcomes of patients with neurogenic bladder who had a urinary artificial sphincter before the age of 18 years old.
- Conditions
- Neurogenic Bladder Disorder, Bladder Dysfunction, Spina Bifida, Urinary Incontinence Due to Urethral Sphincter Incompetence
- Trial name
- SUAPED (NCT06734429)
- Testing
- Urinary Artificial Sphincter
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Clermont-Ferrand
Chronic Kidney Disease, Vitamin D Deficiency
Vitamin D and Coronary Calcification Study
Patients with chronic kidney disease (CKD) have a higher mortality rate than the general population, with cardiovascular disease (CVD) accounting for approximately 50% of deaths.
- Conditions
- Chronic Kidney Disease, Vitamin D Deficiency, Coronary Calcification, Disorders of Calcium and Bone Metabolism
- Trial name
- VCOR (NCT00752102)
- Testing
- Calcitriol (Rocaltrol®), Paricalcitol
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Joslin Diabetes Center
Healthy
Evaluation of IM Letrozole ISM® Pharmacokinetics, Safety, and Tolerability in Healthy Post-menopausal Women (LISA-1)
This is a Phase I, open label, dose escalation study designed to evaluate the pharmacokinetics, safety, and tolerability of single intramuscular injections of Letrozole ISM® at different strengths in voluntary healthy post…
- Trial name
- NCT03401320
- Testing
- Letrozole ISM
- Where
- Czechia
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Rovi Pharmaceuticals Laboratories
Infertility
Drop-out of Infertile Couples: a Large Single Center Experience Over 10 Years
Conducted at a single-center, this prospective-retrospective study focused on all couples who initiated their journey at the Fertility Center of Humanitas Research Hospital, Rozzano (Milan), Italy.
- Trial name
- dropout (NCT06344585)
- Testing
- Drop out patients who had their first access in 2021 were additionally asked to answer to a phone -call questionnaire to assess their motivation of discontinuation
- Where
- Italy
- Volunteers
- 24,773 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Overactive Detrusor
Botulinum Toxin in the Treatment of Idiopathic Detrusor Overactivity
Overactive Bladder (OAB) is a chronic condition caused by instability of the detrusor or bladder muscle, which gives rise to symptoms of urinary urgency and often urinary incontinence.
- Trial name
- NCT02009540
- Testing
- Botulinum toxin injected to bladder body, Botulinum toxin injected into trigone
- Where
- Ireland
- Volunteers
- 60 people
- Sponsor
- Mr HD Flood
Leiomyomata
Safety and Effectiveness of OCL 503 in the Treatment of Women With Leiomyomata
This is a prospective, pilot, open-label, uncontrolled, safety and effectiveness study of uterine artery embolization with OCL 503 in women with leiomyomata who are scheduled for hysterectomy.
- Trial name
- NCT02410018
- Testing
- OCL 503 (uterine artery embolization)
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- IMBiotechnologies Ltd.
Pharmacokinetics of Isavuconazole, Healthy Volunteers
Study of the Pharmacokinetics of Isavuconazole in Healthy Non-Elderly and Elderly Male and Female Subjects
The purpose of this study is to evaluate the pharmacokinetics of isavuconazole in healthy non-elderly and elderly male and female subjects.
- Conditions
- Pharmacokinetics of Isavuconazole, Healthy Volunteers, Safety and Tolerability in Elderly
- Trial name
- NCT01657890
- Testing
- isavuconazole
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Global Development, Inc.
Bioequivalence, Diabetes Mellitus, Type 2
Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 100 mg /1000 mg (FDC) in Healthy Adult Male and Female Subjects Under Fasting Conditions.
The objective of this study was to evaluate and compare the bioavailability and therefore to assess the bioequivalence of two different formulations of sitagliptin/metformin extended release tablets after a single oral dose…
- Trial name
- NCT06124560
- Testing
- Sitagliptin/Metformin HCl 100/1000 mg extended release film-coated tablet
- Where
- Mexico
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Galenicum Health
Myocardial Ischemia
Effect of Dapagliflozin on Microvascular Function in Women With Symptoms of Coronary Artery Disease
The goal of this clinical trial is to test the effects of a drug (in the drug class called sodium-glucose cotransporter 2 inhibitors) in women who have symptoms of ischemic heart disease.
- Trial name
- SMILE (NCT05762952)
- Testing
- Dapagliflozin 10mg Tab
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Virginia
Soil-transmitted Helminth Infection, Onchocerciasis (River Blindness)
A Study to Learn About How Much Emodepside Gets Absorbed in the Blood and How Food Affects Its Absorption When Given as a New Type of Tablet to Healthy Participants
Onchocerciasis or river blindness is an infectious disease caused by a parasitic worm. It spreads through the bite of an infected blackfly.
- Trial name
- NCT06412926
- Testing
- BAY 44-4400
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bayer
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