Clinical trials: Sinonasal Polyposis
Computer Assisted, Navigation
Computer Assisted Navigation on Endoscopic Sinus Surgery for Treatment of Sinonasal Polyposis
This study aimed to compare Endoscopic Sinus Surgery with and without image guidance, analyzing a number of parameters that can impact efficacy in cases of nasal polyposis.
- Conditions
- Computer Assisted, Navigation, Endoscopic Sinus Surgery, Sinonasal Polyposis
- Trial name
- NCT07575022
- Testing
- Endoscopic sinus surgery with Computer Assisted Navigation, Endoscopic sinus surgery
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Nasal Polyps
Comparison of Intraoperative Outcomes of Microdebrider-Assisted Versus Conventional Functional Endoscopic Sinus Surgery in Patients With Sinonasal Polyposis
This study compared two surgical techniques for patients with nasal polyps affecting both sides of the nose and sinuses. Nasal polyps were soft swellings that caused symptoms such as nasal blockage, nasal discharge, and reduced…
- Trial name
- NCT07907393
- Testing
- Microdebrider-Assisted Functional Endoscopic Sinus Surgery, Conventional Functional Endoscopic Sinus Surgery
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Lahore General Hospital
Asthma
Charcot Leyden Crystals in Pathology
Charcot Leyden crystals (CLC) are sometime reported in pathological reports of airway or sinonasal samples but their clinical significance remain elusive.
- Trial name
- CLCpath (NCT03999242)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
CRSwNP, Chronic Rhinosinusitis (Diagnosis), Nasal Polyposis
Inflammatory Profiles, Histopathological Features, and Remodeling Factors in Chronic Rhinosinusitis With Nasal Polyps
This study aims to examine three key aspects of chronic rhinosinusitis with nasal polyps (CRSwNP): inflammation, tissue structure (histopathology), and remodeling.
- Trial name
- 3 Axis (NCT07528820)
- Testing
- Budesonide
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- St. Paul's Sinus Centre
Asthma, Nasal Polyps
ATP Project (Asthma afTer Polypectomy)
Inflammation of the nasal and bronchial mucosa characterizing rhinitis and asthma are probably manifestations of the same disease. Multiple functional observations, pathogenic and clinical support that assertion.
- Trial name
- ATP (NCT02427503)
- Testing
- Asthma with NP and require surgery
- Where
- Spain
- Volunteers
- 106 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Nasal Polyps
Treatment of Post-Operative Sinonasal Polyposis With Topical Furosemide
Prior studies have suggested that topical furosemide may reduce the recurrence of sinonasal polyposis following sinus surgery. This project aims to further investigate that claim through a blinded randomized controlled clinical…
- Trial name
- NCT03362515
- Testing
- Furosemide
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Thomas Jefferson University
Chronic Rhinosinusitis With Nasal Polyps
Dupilumab Treatment Effects in an Ethnically Diverse Population With Chronic Rhinosinusitis With Nasal Polyposis
The central hypothesis of this study is that the addition of dupilumab treatment onto standard-of-care intranasal corticosteroids will improve patient-reported measures of disease activity and sense of smell in a cohort of mostly…
- Trial name
- CRSwNP (NCT05246267)
- Testing
- Dupilumab
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Montefiore Medical Center