Clinical trials: Sinus Disease
Extragonadal Germ Cell Tumor, Teratoma
Combination Chemotherapy in Treating Men With Germ Cell Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Conditions
- Extragonadal Germ Cell Tumor, Teratoma, Testicular Germ Cell Tumor
- Trial name
- NCT00003643
- Testing
- bleomycin sulfate, filgrastim, cisplatin
- Where
- 69 sites in Austria, Belgium and 12 more
- Volunteers
- 498 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Chronic Kidney Disease
Ultrasound to Predict Steal-Syndrome After Arteriovenous-Fistula Creation (UPSAC - Trial)
The purpose of this study is to analyze and identify pre-, intra-, and post- operative parameters that predict Steal-Syndrome with distal malperfusion after Arterio-Venous Fistulas (AVF) as primary endpoint.
- Trial name
- UPSAC (NCT01468506)
- Where
- United States
- Sponsor
- Baptist Health South Florida
Head and Neck Cancer, Lung Cancer
Paclitaxel and Cisplatin Plus Radiation Therapy Followed by Filgrastim in Treating Patients With Recurrent Head and Neck Cancer or Lung Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Trial name
- NCT00021333
- Testing
- filgrastim, cisplatin, paclitaxel
- Where
- 18 sites in United States
- Volunteers
- 29 people
- Sponsor
- Fox Chase Cancer Center
Olfaction Disorders, Sinusitis
Trial of Directed High-dose Nasal Steroids on Residual Smell Loss in Sinus Patients After Sinus Surgery
The purpose of this study is to determine if a trial of directed high-dose nasal steroids improves residual smell loss in patients with chronic rhinosinusitis following sinus surgery.
- Conditions
- Olfaction Disorders, Sinusitis, Paranasal Sinus Diseases
- Trial name
- NCT01814618
- Testing
- Budesonide Respules
- Where
- United States
- Sponsor
- University of North Carolina, Chapel Hill
Pancreatic Cancer, Periampullary Cancer
Tissue Adhesive Glue Modified Cyanoacrylate (Glubran® 2) in Soft Pancreas
This is a single-center, randomized controlled trial comparing the efficacy of pancreaticojejunostomy with modified N-butyl-2-cyanoacrylate(Glubran® 2) versus standard pancreaticojejunostomy without cyanoacrylate in preventing…
- Conditions
- Pancreatic Cancer, Periampullary Cancer, Duodenal Cancer, Cholangiocarcinoma
- Trial name
- NBCA-MS (NCT07155525)
- Testing
- Pancreaticojejunostomy with Modified N-Butyl-2-Cyanoacrylate (Glubran® 2), Standard(duct-to-mucosa) Pancreaticojejunostomy
- Where
- Egypt
- Volunteers
- 194 people
- Sponsor
- Minia University
Sinusitis, Chronic Rhinosinusitis
Prednisone in Chronic Rhinosinusitis Without Nasal Polyps
The purpose of this study is to determine whether prednisone is effective in the treatment of chronic rhinosinusitis without nasal polyps in adult patients.
- Trial name
- NCT02367118
- Testing
- Prednisone
- Where
- Chile
- Volunteers
- 90 people
- Sponsor
- University of Chile
Sinus Node Dysfunction
Permanent Pacemaker Implantation or Cardioneuroablation in Sinus Node Dysfunction
This is a noncommercial, physician-initiated, monitored, multicenter, prospective randomized clinical trial, a proof-of-concept study, investigating a treatment strategy only.
- Trial name
- SANOK (NCT05196126)
- Testing
- Permament pacemaker implantation, Cardioneuroablation
- Where
- 4 sites in Poland
- Volunteers
- 60 people
- Sponsor
- Stec, Sebastian, MD, PhD, FESC
Sinusitis
Rates of Middle Meatus Synechiae Formation Post ESS
The study is designed to evaluate if addition of the steroid to the spacer / stent will improve healing after endoscopic sinus surgery (ESS) compared to spacer without drug.
- Trial name
- NCT03036735
- Testing
- steroid eluting spacer
- Volunteers
- 10 people
- Sponsor
- Steward St. Elizabeth's Medical Center of Boston, Inc.
Pancreatic Fistula
Total pancrEaTectomy vs High-Risk Pancreatic anastomosiS
Postoperative pancreatic fistula (POPF) is the main driver of surgical morbidity after pancreatoduodenectomy (PD). The aim of the present study is to compare total pancretectomy (TP) and primary pancreatic anastomosis (PA) in a…
- Trial name
- TETRIS (NCT05212350)
- Testing
- Total pancreatectomy, Pancreatic anastomosis
- Where
- 5 sites in Germany, Italy
- Volunteers
- 98 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Rhinosinusitis, Headache
Effect of Low Level Laser Therapy in Patients With Chronic Rhinosinusitis.
This study aimed to evaluate the efficacy of low-level laser therapy (LLLT) for Chronic sinusitis in a randomized, double-blind, placebo-controlled trial.
- Conditions
- Rhinosinusitis, Headache, Fatigue, CT
- Trial name
- Sinusitis (NCT05861817)
- Testing
- Laser theapy
- Where
- 2 sites in Egypt
- Volunteers
- 31 people
- Sponsor
- Cairo University
Vesico-vaginal Fistula
Clinical Evaluation of the Surgisis Biodesign Vesico-Vaginal Fistula Plug
This clinical trial will study the safety and effectiveness of the Biodesign Vesico-vaginal fistula plug in the treatment of vesico-vaginal fistulas resulting from childbirth trauma.
- Trial name
- VVP (NCT00923338)
- Testing
- Surgisis Biodesign (Vesico-vaginal fistula plug)
- Where
- Uganda
- Volunteers
- 20 people
- Sponsor
- Cook Group Incorporated
Cystectomy, Segmental Growing of Alveolar Tissue
Study of Collagen Membrane in Guided Bone Regeneration
The main purpose of this study is to investigate the efficacy of Hypro-Sorb® F, a bilayered bioabsorbable membrane in inducing bone regeneration in different dental procedures requiring GBR.
- Conditions
- Cystectomy, Segmental Growing of Alveolar Tissue, Sinus Lift, Root Amputation and Apicoectomy
- Trial name
- GBR (NCT00454038)
- Testing
- HYPRO SORB F
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Migraine, Tension-Type Headache
Carotid Sinus Massage in Trendelenburg Position for Headache Relief
Headaches significantly impact patients' quality of life, with tension-type headaches and migraines being among the most prevalent types.
- Trial name
- NCT06745648
- Testing
- Arm A - Carotid Sinus Massage + Trendelenburg (CSM+T)
- Where
- Argentina
- Volunteers
- 18 people
- Sponsor
- Hospital Municipal Pedro T. Orellana
Kidney Disease, End-Stage, End-stage Renal Disease
Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System
A prospective, single-arm, multi-center post-market surveillance study of the BD® WavelinQ™ EndoAVF System for the Creation of Arteriovenous (AV) Fistula in Patients Requiring Dialysis.
- Conditions
- Kidney Disease, End-Stage, End-stage Renal Disease, Arteriovenous Fistula
- Trial name
- CONNECT-AV (NCT04634916)
- Testing
- EndoAVF Creation
- Where
- 17 sites in United States, Australia
- Volunteers
- 220 people
- Sponsor
- C. R. Bard
Chronic Sinusitis, Nasal Polyposis
FESS With or Without Intranasal Desmopressin in Chronic Rhinosinusitis With Nasal Polyps
Chronic rhinosinusitis with nasal polyps is a condition that causes long-lasting inflammation and swelling in the nose and sinuses and may lead to nasal blockage, nasal discharge, facial pressure, and reduced sense of smell.
- Trial name
- NCT07855315
- Testing
- Desmopressin Acetate Nasal, 10 μg/0.1 ml per spray, Functional Endoscopic Sinus Surgery
- Volunteers
- 174 people
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Arteriovenous Fistula, Ultrasound
Relationship Between Arterial Variations and Patency of Arteriovenous Fistulae
In 2019, KDOQI considered that uremic patients with a life expectancy of more than one year should require hemodialysis as an effective renal replacement therapy before preparation of kidney transplantation.
- Conditions
- Arteriovenous Fistula, Ultrasound, Artery
- Trial name
- NCT04613115
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Cardiac Disease, Syncope
Second Study on Cardio-neuromodulation in Humans
Different approaches to cardio-neuroablation (CNA) to treat neurally mediated syncope, sinus node dysfunction, and functional atrioventricular block have been published.
- Conditions
- Cardiac Disease, Syncope, Syncope, Vasovagal, Sick Sinus Syndrome
- Trial name
- CardNMH2 (NCT02954666)
- Testing
- radio-frequency ablation
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Imelda Hospital, Bonheiden
Healing Rate, Recurrence
Anal Fistula Plug, a Retrospective Study
In this study, we retrospectively reviewed clinical data of patients who were treated with an anal fistula plug for trans-sphincteric anal fistulas, and evaluated the long-term therapeutic effect of an anal fistula plug and the…
- Conditions
- Healing Rate, Recurrence, Complication
- Trial name
- NCT04319861
- Testing
- Anal fistula plug procedure
- Where
- China
- Volunteers
- 207 people
- Sponsor
- Zhen Jun Wang
Childhood Extracranial Germ Cell Tumor, Childhood Extragonadal Malignant Germ Cell Tumor
Combination Chemotherapy in Treating Young Patients With Recurrent or Resistant Malignant Germ Cell Tumors
This phase II trial is studying how well giving combination chemotherapy works in treating young patients with recurrent or resistant malignant germ cell tumors.
- Conditions
- Childhood Extracranial Germ Cell Tumor, Childhood Extragonadal Malignant Germ Cell Tumor, Childhood Malignant Ovarian Germ Cell Tumor, Childhood Malignant Testicular Germ Cell Tumor
- Trial name
- NCT00467051
- Testing
- Carboplatin, Filgrastim, Ifosfamide
- Where
- 95 sites in United States, Australia and 2 more
- Volunteers
- 20 people
- Sponsor
- Children's Oncology Group
Fistula in Ano
PRP Use in Treatment of Fistula Ano
In treatment of perianal fistula several methods are described. However, since the Hippocrates basics of surgical treatment has not changed very much.
- Trial name
- NCT04187651
- Testing
- platelet rich plasma
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Uşak University
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