Clinical trials: Sinus Infection
Sinusitis, Periodontal Disease
Endoscopic Assessment of Schneiderian Membrane Perforation During Osseodensification-mediated Transcrestal Sinus Floor Elevation With Graftless Immediate Implant Placement in Subsinus Bone Height of 4-6 mm: A Pilot Study.
This present study will evaluate Schneiderian membrane perforation rates using osseodensification in TSFE with simultaneous graftless implant placement, under sinuscopic control monitored by an ENT specialist.
- Trial name
- NCT07542275
- Testing
- Scheiderian Membrane Perforation
- Where
- Lebanon
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Sinusitis in Children
Pediatric Chronic Rhinosinusitis in Asthmatic Children
The objectives of this study would be to determine the most effective treatment for children with PCRS and asthma who fail medical management.
- Trial name
- NCT06194097
- Testing
- adenoidectomy versus endoscopic sinus surgery with adenoidectomy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Chronic Sinus Infection
Use of Perioperative Antibiotics in Endoscopic Sinus Surgery
The objective of this study is to determine whether the use of postoperative antibiotics following endoscopic sinus surgery (ESS) decreases postoperative infection rates.
- Trial name
- NCT03369717
- Testing
- Amoxi Clavulanate
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Antibiotic Associated Diarrhea, Acute Otitis Media
Effects of Saccharomyces Boulardii CNCM I-745 on Antibiotic-Associated Perturbation in Children Treated for Acute Respiratory Infections (RESTORE Study)
This study aims to evaluate the effect of co-administering the probiotic Saccharomyces boulardii CNCM I-745 with amoxicillin-clavulanic acid on the intestinal and nasopharyngeal microbiota in children diagnosed with acute otitis…
- Conditions
- Antibiotic Associated Diarrhea, Acute Otitis Media, ACUTE SINUSITIS
- Trial name
- RESTORE (NCT07015736)
- Testing
- Amoxicillin-Clavulanic acid 600mg - 42.9 mg/ 5 mL oral suspension, Saccharomyces boulardii CNCM I-745
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Vascular Graft Infection, Infectious Aortitis
China Aortic Infection and Graft Infection Study: An Ambispective Cohort
Vascular infections are uncommon but severe infections involving the arterial wall, vascular grafts, or endografts, and their diagnosis and management remain challenging.
- Conditions
- Vascular Graft Infection, Infectious Aortitis, Aortoenteric Fistula
- Trial name
- CAIGIS (NCT07847346)
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Acne Vulgaris, Allergic Rhinitis
MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use
The specific aim of this proposed pilot study is to compare two standardized processes (paper and electronic) to deliver a customized MedlinePlus health information prescription.
- Conditions
- Acne Vulgaris, Allergic Rhinitis, Anxiety, Asthma
- Trial name
- NCT01050465
- Testing
- health information prescription
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Upper Respiratory Tract Infections, Rhinopharyngitis
Effect of the Consumption of a Fermented Milk on Common Infections in Adults Submitted to Multi-stressor Situation
This multicentric, randomized, double-blind and controlled study aims to examine the effect of a fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel® = tested product) on the incidence of…
- Conditions
- Upper Respiratory Tract Infections, Rhinopharyngitis, Sore Throat, Sinusitis
- Trial name
- NCT01315418
- Testing
- 1-Fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel®), 2-Non fermented dairy product (control)
- Where
- France
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Sinus Floor Augmentation, Sinus Infection
Maxillary Sinus Membrane Perforation Incidence During Osseodensification
Measure the incidence of the maxillary sinus membrane perforation during the Osseodensification crestal sinus grafting procedure.
- Trial name
- NCT05954273
- Testing
- Osseodensification crestal sinsus graft
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Versah
Endoscopic Sinus Surgery, Chronic Rhinosinusitis
Large Scale Cerebral Oximetry During Sinus Endoscopy
Deliberate hypotension, reverse Trendelenburg position, and hyperventilation are techniques utilized during functional endoscopic sinus surgery to attempt to reduce surgical bleeding.
- Trial name
- NCT02692794
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chronic Sinusitis, Rhinosinusitis
Chronic Rhinosinusitis With or Without Nasal Polyps Steroid Study
This is a study to evaluate the cause of chronic sinus disease. Oral steroids have long been used in the treatment of inflammatory conditions including chronic sinusitis, asthma, and arthritis.
- Conditions
- Chronic Sinusitis, Rhinosinusitis, Nasal Polyps
- Trial name
- NCT00841802
- Testing
- Prednisone
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Chronic Rhinosinusitis Without Nasal Polyps, Asthma
Adherence in Global Airways - Steroid Intake and Effects on Chronic Rhinosinosinutis
The purpose of this study is to investigate the relationship between long-term use of systemic steroids in patients with upper and lower respiratory tract diseases and their own production of cortisol (cross-sectional), as well…
- Conditions
- Chronic Rhinosinusitis Without Nasal Polyps, Asthma, Chronic Rhinosinusitis With Nasal Polyps, Steroid-Induced Osteopenia (Diagnosis)
- Trial name
- AGAS 2023 (NCT05843019)
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Christiane Haase
Chronic Sinusitis
Assessing Improvement in Cognitive Deficit in CRS in Patients Treated With Medical Vs Surgical Management
Chronic rhinosinusitis presents with a plethora of symptoms including non-rhinologic symptoms such as depression, sleep disturbances \& the more recently recognized cognitive dysfunction.
- Trial name
- NCT04291118
- Testing
- Private system endoscopic sinus surgery, Public system endoscopic sinus surgery, Budesonide
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- St. Paul's Hospital, Canada
Sinusitis, Nasal Polyps
The Polymerase Chain Reaction (PCR) Analysis of Nasal Polyps for Fungal DNA
The objective of this study is to determine whether the amount or type of fungal DNA present in the nose and home environment can be correlated with the outcomes of the following quality of life (QOL) instruments: Medical…
- Trial name
- NCT00739921
- Testing
- Nasal swab under endoscopic guidance
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Sinusitis
Near Infrared Transillumination of the Paranasal Sinuses
This research project designed to diagnose sinusitis using a simple and low-cost optical tool. Healthy sinuses are typically filled with air, and show up as bright spots on the camera.
- Trial name
- NCT00543998
- Testing
- Optical Measurement transillumination
- Where
- 2 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Infectious Diseases, Healthy Subjects
Effect of the Consumption of a Fermented Milk on Common Infections in Shift-workers
This single-center, randomized, double-blind and controlled study aims to examine the effect of a fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel® = tested product) on the incidence of…
- Conditions
- Infectious Diseases, Healthy Subjects, Respiratory Tract Infections, Sore Throat
- Trial name
- NCT01033799
- Testing
- Fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel®), Non fermented dairy product (control)
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Chronic Obstructive Pulmonary Disease (COPD), Asthma Patients
Evaluation of Nasal Biomarkers for Objective Assessment of Disease Severity in Respiratory Disorders
This research study is an observational, single site study quantifying expression of biomarkers of respiratory disease in nasal fluid using the ABEL microsampler device.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Asthma Patients, Asthma and Rhinitis, Asthmatic Patients
- Trial name
- ENBOARD (NCT06661252)
- Testing
- ABEL microsampler device
- Where
- Australia
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Diag-Nose Medical Pty Ltd
Chronic Sinus Infection, Chronic Sinusitis
Impact of Budesonide Irrigations on Patients With Chronic Rhinosinusitis and Impact on Sinus Surgery Rates
This study is intended to assess the impact of a 90 day course of high volume budesonide irrigations for patients who have failed other medical therapy and assessing the impact of the budesonide irrigations on the need for sinus…
- Conditions
- Chronic Sinus Infection, Chronic Sinusitis, Chronic Sinusitis - Ethmoidal, Posterior, Chronic Sinus Congestion
- Trial name
- NCT03519061
- Testing
- Budesonide
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Allergic Fungal Rhinosinusitis
Sinonasal Risk Factors for Occurrence of Unilateral Versus Bilateral Allergic Fungal Rhinosinusitis .
This study aims to assess Sinonasal risk factors for occurrence of unilateral versus bilateral allergic fungal rhino sinusitis regarding:: 1. anatomical variations and correlate radiological finding with intraoperative finding.
- Trial name
- NCT06376071
- Testing
- functional endoscopic sinus surgery
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Assiut University
Rhino Sinusitis
Safety Evaluation of Intranasal Use of DSM 32444 Postbiotic in Humans
Rhinitis is a type of upper respiratory infection with a common nasal pathology especially in Southeast Asia, which is characterized by the presence of one or more of the following symptoms: itchy nose, sneezing, runny nose, and…
- Trial name
- NCT05984004
- Testing
- 0.9% NaCl isotonic saline solution, Bacillus subtilis DSM32444, inactivated
- Where
- Vietnam
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Huro Biotech Joint Stock Company
Sinusitis
Safety of Intranasal Irrigation Probiotics in Healthy Volunteers
Chronic rhinosinusitis (CRS) is one of the most common chronic diseases, affecting the quality of life of patients who suffer. Despite medical and surgical treatments available, there are a significant number of people suffering…
- Trial name
- NCT02933918
- Testing
- Probiotics
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Probionase Therapies Inc.