Clinical trials: Sinus Surgery
Endonasal Surgery, Endoscopic Sinus Surgery
In Vivo Imaging of the Olfactory Epithelium Using Confocal Laser Endomicroscopy
This research is being done to better characterize the part of the nose that helps people smell. Currently, the only ways to study smell loss mostly rely on how people report it, rather than being able to see the underlying…
- Conditions
- Endonasal Surgery, Endoscopic Sinus Surgery, Olfactory Dysfunction
- Trial name
- NCT07546617
- Testing
- CONVIVO system, Fluorescein injection, USP 10%
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Chronic Sinus Disease, Surgery
Efficacy of PuraSinus Versus Bioresorbable Nasal Dressings
Postoperative care of patients undergoing endoscopic sinus surgery (ESS) is important both to minimize discomfort for the patients and to obtain the optimal long-term outcomes.
- Trial name
- NCT04970966
- Testing
- PuraSinus, Bioresorbable Nasal Dressing
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Patients with Posterior Maxillary Atrophy and Need for Sinus Lift Surgery to Allow Implant Placement
Efficacy of L-PRF Against Deproteinized Bovine Mineralized Bone (DBBM)
Objective: The main objective of this study is to evaluate whether the use of L-PRF combined with deproteinized bovine mineralized bone (DBBM; BioOss, Geistlich Pharma®) reduces healing time, through histomorphometric analysis…
- Trial name
- NCT06686836
- Testing
- Sinus lift augmentation with bone substitute (Bio-Oss), Open sinus lift surgery lift using Platelet- and leukocyte-rich fibrin (L-PRF) mixed with a bone substitute (Bio-Oss®(Geistlich AG, Wolhusen, Switzerland)) - L-PRF Block
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Sinus; Dental, Implant Complication
Evaluation of the Efficacy of Allograft Versus Tenting Technique in Open Sinus Lifting With Immediate Implant Placement
Implant placement in deficient posterior maxilla is a challenging clinical situation that necessitates appropriate treatment options to restore this area.
- Conditions
- Sinus; Dental, Implant Complication, Surgery-Complications
- Trial name
- NCT06254378
- Testing
- Sinus lifting with allograft, Sinus lifting without graft
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Aminophylline, Dexmedetomidine
Aminophylline on Recovery in Functional Endoscopic Sinus Surgery Under Dexmedetomidine Hypotensive Anesthesia
This study will be conducted to evaluate the effect of intravenous aminophylline on hemodynamics and recovery of patients receiving dexmedetomidine infusion during functional endoscopic sinus surgery.
- Conditions
- Aminophylline, Dexmedetomidine, Functional Endoscopic Sinus Surgery
- Trial name
- NCT05738135
- Testing
- Aminophylline group, normal saline
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tanta University
Chronic Rhinosinusitis, Rhinosinusitis
Xylitol for Chronic Sinusitis
The purpose of this investigation is to conduct a randomized controlled trial within a subgroup of difficult-to-treat patients with CRS, evaluating the use of topical xylitol treatment concurrently with topical…
- Conditions
- Chronic Rhinosinusitis, Rhinosinusitis, Sinusitis, Drain Sinus
- Trial name
- NCT03229551
- Testing
- Xylitol, Saline
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Endoscopic Sinus Surgery, Heart Rate
Comparative Study Between the Efficacy of Verapamil and Bisoprolol on Reduction of Bleeding During Endoscopic Sinus Surgery Under General Anaesthesia.
The study aims to compare the effect of addition of verapamil and Bisoprolol to general anasthesia aimed reduction in heart rate and blood loss during endoscopic sinus surgery.
- Conditions
- Endoscopic Sinus Surgery, Heart Rate, Blood Loss
- Trial name
- NCT04356196
- Testing
- Verapamil, Bisoprolol
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Assiut University
Chronic Rhinosinusitis, Endoscopic Sinus Surgery
Perioperative Oral Steroids for Chronic Rhinosinusitis Without Polyps (CRSsNP)
While oral steroids have been shown to be effective in the management of patients with chronic rhinosinusitis with polyps, its role in treating chronic rhinosinusitis without polyps (CRSsNP) is ambiguous.
- Conditions
- Chronic Rhinosinusitis, Endoscopic Sinus Surgery, Chronic Rhinosinusitis Without Polyps, Oral Steroids
- Trial name
- NCT02748070
- Testing
- Prednisone, Flonase
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Stanford University
Endoscopic Sinus Surgery, Chronic Rhinosinusitis
Large Scale Cerebral Oximetry During Sinus Endoscopy
Deliberate hypotension, reverse Trendelenburg position, and hyperventilation are techniques utilized during functional endoscopic sinus surgery to attempt to reduce surgical bleeding.
- Trial name
- NCT02692794
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai