Clinical trials: Sinus Tract
Nasal Polyps, Chronic Sinusitis
Wound Healing After Endoscopic Sinus Surgery
This study aims to determine the effect of Thymoquinone (0.5%) and olive oil ointment on Wound healing after Endoscopic sinus surgery.
- Trial name
- NCT06070311
- Testing
- Thymoquinone (0.5%) and Olive oil ointment
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Vascular Access Complication, Apheresis Related Complication
Vascular Access Complications for Therapeutic Apheresis in Nephrology
The aim of this study is to describe vascular access complications which are used for therapeutic apheresis in Nephrology.
- Trial name
- VACTANE (NCT05894317)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Rhinosinusitis
Allele-specific Expression of a Bitter Taste Receptor
This single-site, within-subject experimental basic research study is designed to analyze the hypothesis that allele-specific expression of the bitter taste receptor T2R38 in taste tissue of individuals heterozygous for the taste…
- Trial name
- NCT02766959
- Testing
- Observational study
- Where
- 3 sites in United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Monell Chemical Senses Center
Rhinosinusitis
Study of Cefditoren Pivoxil in Treatment of Childhood With Acute Rhinosinusitis
Cefditoren pivoxil has been used in rhinosinusitis treatment. However, little is known about the efficacy of this drug at low and high doses.
- Trial name
- RS (NCT01553006)
- Testing
- cefditoren pivoxil
- Where
- Thailand
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Nasal Disease
Investigating the Effect of Herbal Medicine Nasal Irrigation on Treatment of Chronic Rhinitis and Sinusitis
This study investigate the nasal irrigation with Traditional herbal medicine extract-saline isotonic solution in the treatment of chronic rhinitis and sinusitis.
- Trial name
- NCT04046393
- Testing
- Taiwan Scientific" noninvasive blood pressure meter TS-0411, Meridian Energy Analysis Device(MEAD), bacteria culture
- Where
- Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Anaesthesia, Rhinitis
A Comparison Between Co-phenylcaine Nasal Spray and Nasal Nebulization Prior to Rigid Nasoendoscopic Examination
Co-phenylcaine is a widely available nasal spray commonly used by otorhinolaryngologists for the purpose of decongestion and local anesthetic prior to a nasoendoscopic or nasopharyngolaryngoscopy.
- Trial name
- NCT03380715
- Testing
- Nasal nebulisation into the right nostril, Nasal Spray into the right nostril
- Where
- 2 sites in Malaysia
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Maxillary Sinus Neoplasms
Temporalis Myofascial Flap Effectiveness
This research is conducted as trial to improve lifestyle of patients with cranio-maxillofacial defects following major insults like trauma or tumor resection in form of speech problems or dysphagia by usage temporalis myofascial…
- Trial name
- NCT05298969
- Testing
- Temporalis Myofascial flap
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Assiut University
Sinusitis
Clinical Trial of the Treatment of Acute Sinusitis With Standard-dose Versus High-dose Amoxicillin/Clavulanate
The aim is to determine if high-dose amoxicillin/clavulanate is more effective than standard-dose amoxicillin/clavulanate in treating acute bacterial sinusitis in adults seen at a primary care office.
- Trial name
- NCT02340000
- Testing
- standard dose amoxicillin/clavulanate, high dose amoxicillin/clavulanate
- Where
- United States
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Allergic Rhinitis, Asthma
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow.
- Conditions
- Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy
- Trial name
- NCT00634608
- Testing
- Health Information Prescription
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Acute Otitis Media, Allergic Rhinitis
A Trial of Point of Care Information in Ambulatory Pediatrics
Does presentation of clinical evidence for decision making at point-of-care improve prescribing patterns in ambulatory pediatrics?
- Conditions
- Acute Otitis Media, Allergic Rhinitis, Sinusitis, Constipation
- Trial name
- NCT00368823
- Testing
- Electronic point-of-care delivery system
- Where
- 2 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Washington
Nasal Polyps, Sinusitis
Study to Compare Resection Versus Preservation of the Middle Turbinate in Surgery for Nasal Polyps
Endoscopic sinus surgery (ESS) has become the standard of care for patients suffering of chronic rhinosinusitis with nasal polyposis (CRSwP) who have failed medical therapy.
- Trial name
- NCT02855931
- Testing
- Middle turbinate resection
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Nasal Polyps
Infrazygomatic Versus Intranasal Injection Sphinopalatine Ganglion Blockade Effect on Surgical Field in FESS
This study aimed to show the effect of sphinopalatine ganglion blockade on surgical field, hemodynamics and postoperative pain in FEES operation.
- Trial name
- NCT04996576
- Testing
- infrazygomatic approach sphinopalatine ganglion block, intranasal injection approach of sphinopalatine ganglion block
- Where
- 2 sites in Egypt
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Sinusitis
Near Infrared Transillumination of the Paranasal Sinuses
This research project designed to diagnose sinusitis using a simple and low-cost optical tool. Healthy sinuses are typically filled with air, and show up as bright spots on the camera.
- Trial name
- NCT00543998
- Testing
- Optical Measurement transillumination
- Where
- 2 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Nasal Polyps, Sinusitis
Dupixent Study for Alternate Administration
Investigators will investigate an alternate Dupilumab administration schedule in patients with recurrent chronic rhinosinusitis with nasal polyposis, who have a history of full endoscopic sinus surgery and are on appropriate…
- Conditions
- Nasal Polyps, Sinusitis, Chronic Disease
- Trial name
- NCT06750471
- Testing
- Dupilumab
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Sinusitis
Effect of Squeezable Bottle Nasal Irrigation Device in Children With Sinusitis
The purpose of this study is to the effect of squeezable bottle nasal irrigation device with syringe in children with sinusitis in symptom score and satisfaction to nasal irrigation
- Trial name
- NCT02191046
- Testing
- squeezable bottle, syringe 20 ml
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Rhino Sinusitis
Safety Evaluation of Intranasal Use of DSM 32444 Postbiotic in Humans
Rhinitis is a type of upper respiratory infection with a common nasal pathology especially in Southeast Asia, which is characterized by the presence of one or more of the following symptoms: itchy nose, sneezing, runny nose, and…
- Trial name
- NCT05984004
- Testing
- 0.9% NaCl isotonic saline solution, Bacillus subtilis DSM32444, inactivated
- Where
- Vietnam
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Huro Biotech Joint Stock Company
Rhinosinusitis
Prospective Study Investigating the Role of Occupational Exposure on Sinus Surgery Outcome
The pathophysiology of chronic rhinosinusitis (CRS) is complex and involves several immune, infectious and anatomic factors. When medical therapy fails, functional endoscopic sinus surgery (FESS) is the therapy of choice.
- Trial name
- NCT01350466
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Chronic Rhinosinusitis, Rhinosinusitis
Xylitol for Chronic Sinusitis
The purpose of this investigation is to conduct a randomized controlled trial within a subgroup of difficult-to-treat patients with CRS, evaluating the use of topical xylitol treatment concurrently with topical…
- Conditions
- Chronic Rhinosinusitis, Rhinosinusitis, Sinusitis, Drain Sinus
- Trial name
- NCT03229551
- Testing
- Xylitol, Saline
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Migraine, Sinusitis
Evaluation of Histamine, CGRP and VIP as Markers for Activation of Trigeminal and Parasympathetic Nerve Fibers
The primary objective of this study is to evaluate histamine, CGRP and VIP levels in saliva as biological markers for activation of trigeminal and parasympathetic nerve fibers in various clinical presentations of primary…
- Trial name
- NCT00208065
- Testing
- almotriptan or pseudoephedrine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Clinvest
Sinus Floor Augmentation, Sinus Infection
Maxillary Sinus Membrane Perforation Incidence During Osseodensification
Measure the incidence of the maxillary sinus membrane perforation during the Osseodensification crestal sinus grafting procedure.
- Trial name
- NCT05954273
- Testing
- Osseodensification crestal sinsus graft
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Versah