Clinical trials: Sinusitis, Chronic
Conscripts, Military Induction Board
Prevalence of ENT Diseseas
The aim of the present study will be to evaluate in conscripts at the military induction board the prevalence of rhinosinusitis, the prevalence of HPV vaccinations, the prevalence of hearing impairments and the prevalence of…
- Conditions
- Conscripts, Military Induction Board, ENT Disease, Rhinosinusitis Chronic
- Trial name
- PrENT (NCT06105346)
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Sinusitis
Gold Laser Vs. Micro-Debriders for Functional Endoscopic Sinus Surgery
Sinusitis is a common medical problem, which significantly decreases patients' quality of life (QOL). Patients may have symptoms such as headaches, sinus pressure, nasal congestion and drainage, decreased sense of smell, and…
- Trial name
- NCT02900794
- Testing
- Gold Laser, Microdebridement
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Sinusitis in Children
Pediatric Chronic Rhinosinusitis in Asthmatic Children
The objectives of this study would be to determine the most effective treatment for children with PCRS and asthma who fail medical management.
- Trial name
- NCT06194097
- Testing
- adenoidectomy versus endoscopic sinus surgery with adenoidectomy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Rhinosinusitis
The Efficacy and Complication of Gentamicin Nasal Irrigation in Chronic Rhinosinusitis and Recurrent Sinusitis
Topical antibiotic therapy in patients with refractory sinusitis has been shown to improve symptoms, quality of life, and mucosal aspect.
- Trial name
- NCT02582099
- Testing
- Gentamicin nasal irrigation, Normal saline nasal irrigation
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Rhino Sinusitis
Safety Evaluation of Intranasal Use of DSM 32444 Postbiotic in Humans
Rhinitis is a type of upper respiratory infection with a common nasal pathology especially in Southeast Asia, which is characterized by the presence of one or more of the following symptoms: itchy nose, sneezing, runny nose, and…
- Trial name
- NCT05984004
- Testing
- 0.9% NaCl isotonic saline solution, Bacillus subtilis DSM32444, inactivated
- Where
- Vietnam
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Huro Biotech Joint Stock Company
Nasal Polyps, Sinusitis
Dupixent Study for Alternate Administration
Investigators will investigate an alternate Dupilumab administration schedule in patients with recurrent chronic rhinosinusitis with nasal polyposis, who have a history of full endoscopic sinus surgery and are on appropriate…
- Conditions
- Nasal Polyps, Sinusitis, Chronic Disease
- Trial name
- NCT06750471
- Testing
- Dupilumab
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Sinusitis
Immunologic Aspects of the Pathogenesis of Chronic Sinusitis in Children
Chronic sinusitis is a common pediatric disease; it ranks among the top five infectious diseases of the upper respiratory tract. Its treatment is limited and may be due largely in part to a lack of understanding of its cause.
- Trial name
- NCT00004638
- Testing
- pathogenesis study
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Chronic Sinusitis, Rhinosinusitis
Chronic Rhinosinusitis With or Without Nasal Polyps Steroid Study
This is a study to evaluate the cause of chronic sinus disease. Oral steroids have long been used in the treatment of inflammatory conditions including chronic sinusitis, asthma, and arthritis.
- Conditions
- Chronic Sinusitis, Rhinosinusitis, Nasal Polyps
- Trial name
- NCT00841802
- Testing
- Prednisone
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Chronic Sinusitis
Distribution of Topical Nasal Medication Within the Nasal Cavity and Sinuses by Radiographic Comparison
The purpose of this study is to determine the distribution of nasal sprays and nasal drops when used.
- Trial name
- NCT00626366
- Testing
- Sinus CT Scan, Omnipaque 240 Contrast Solution, Omnipaque 240 mg I/mL
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Nasal Polyps, Chronic Sinusitis
Wound Healing After Endoscopic Sinus Surgery
This study aims to determine the effect of Thymoquinone (0.5%) and olive oil ointment on Wound healing after Endoscopic sinus surgery.
- Trial name
- NCT06070311
- Testing
- Thymoquinone (0.5%) and Olive oil ointment
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Chronic Rhinosinusitis With Polyposis, Chronic Hyperplastic Sinusitis
Intravenous Tranexamic Acid and Intraoperative Visualization During Functional Endoscopic Sinus Surgery
Functional endoscopic sinus surgery (FESS) is an effective treatment of sinus disease. FESS is carried out using cameras to view the surgical field. Bleeding during the surgery can lead to poor surgical field visualization.
- Trial name
- NCT01111669
- Testing
- Tranexamic Acid
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Acne Vulgaris, Allergic Rhinitis
MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use
The specific aim of this proposed pilot study is to compare two standardized processes (paper and electronic) to deliver a customized MedlinePlus health information prescription.
- Conditions
- Acne Vulgaris, Allergic Rhinitis, Anxiety, Asthma
- Trial name
- NCT01050465
- Testing
- health information prescription
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Sinus Disease
Peppermint and Decongestant Technique on Chronic Sinusitis
Chronic rhinosinusitis (CRS) is defined as persistent symptomatic inflammation of the nasal and sinus mucosa that lasts more than 3 months.
- Trial name
- peppermint (NCT07866937)
- Testing
- Sinus self-massage and inhalation of steated boiled peppermint
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Assiut University
Chronic Sinusitis
The Hemostatic and Hemodynamic Effects of Adrenaline During Endoscopic Sinus Surgery
Obtaining adequate hemostasis is crucial during endoscopic sinus surgery. Submucosal injection of local anaesthetic containing adrenaline has frequently been used to improve surgical milieu.
- Trial name
- NCT00852410
- Testing
- 1% lidocaine with 1:100,000 adrenaline, 1% lidocaine with 1:200,000 adrenaline
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Toronto
CRS
Applications of Nanotechnology and Chemical Sensors for the Detection and Identification of Chronic Sinusitis Subtypes by Respiratory Samples
Professor Hossam Haick from the Technion, developed an electronic nose for diagnosis of diseases via breath samples. Biomarkers from nose and sinuses and upper respiratory tract can be detected by "electronic nose".
- Trial name
- NCT03379701
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Chronic Sinus Infection, Chronic Sinusitis
Impact of Budesonide Irrigations on Patients With Chronic Rhinosinusitis and Impact on Sinus Surgery Rates
This study is intended to assess the impact of a 90 day course of high volume budesonide irrigations for patients who have failed other medical therapy and assessing the impact of the budesonide irrigations on the need for sinus…
- Conditions
- Chronic Sinus Infection, Chronic Sinusitis, Chronic Sinusitis - Ethmoidal, Posterior, Chronic Sinus Congestion
- Trial name
- NCT03519061
- Testing
- Budesonide
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Chronic Rhinosinusitis, Rhinosinusitis
Xylitol for Chronic Sinusitis
The purpose of this investigation is to conduct a randomized controlled trial within a subgroup of difficult-to-treat patients with CRS, evaluating the use of topical xylitol treatment concurrently with topical…
- Conditions
- Chronic Rhinosinusitis, Rhinosinusitis, Sinusitis, Drain Sinus
- Trial name
- NCT03229551
- Testing
- Xylitol, Saline
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Sinusitis, Chronic, Sinus Disease
Microbiota Transfer for Chronic Rhinosinusitis
Chronic sinusitis (CRS) is a common inflammatory condition of the sinuses that affects up to 2.5% of the Canadian population, and is thought to be caused by bacterial infection, resistant biofilms, chronic inflammation and…
- Conditions
- Sinusitis, Chronic, Sinus Disease, Sinus Infection, Sinus Infection Chronic
- Trial name
- SNMT (NCT05454072)
- Testing
- Sinonasal Microbiota Transfer
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Amin Javer
Chronic Sinusitis
The PIO (Propel In Office) III Study of In-office Placement of a Steroid-Eluting Implant Immediately Following Ethmoid Sinus Surgery
Report on the technical feasibility and outcomes of in-office placement of PROPEL or PROPEL mini implants immediately following ethmoid sinus surgery
- Trial name
- NCT02687438
- Testing
- Steroid-releasing sinus implant, Post-op standard of care
- Where
- 4 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ENT and Allergy Associates, LLP
Endoscopic Sinus Surgery, Chronic Rhinosinusitis
Large Scale Cerebral Oximetry During Sinus Endoscopy
Deliberate hypotension, reverse Trendelenburg position, and hyperventilation are techniques utilized during functional endoscopic sinus surgery to attempt to reduce surgical bleeding.
- Trial name
- NCT02692794
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai