Clinical trials: Sjögren Syndrome
Primary Sjögren Syndrome, Sarcopenia
Possible Sarcopenia, Sarcopenia, and Functional Status in Patients With Primary Sjögren's Syndrome
The aim of this study is to evaluate the frequency of probable sarcopenia and sarcopenia in patients with primary Sjögren syndrome and to investigate the effects of sarcopenia on functional status, muscle strength, and quality of…
- Trial name
- NCT07804719
- Testing
- dexa, hand grip strength, myostatin, follistatin
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Antalya Training and Research Hospital
Rheumatoid Arthritis, Systemic Lupus
Combined Pneumococcal Conjugate and Polysaccharide Vaccination in Inflammatory Rheumatic Disease
The overall objective of this project is to study the influence of modern anti-inflammatory treatments in established inflammatory rheumatic diseases (IRD) on antibody response elicited by pneumococcal vaccination using 13-valent…
- Conditions
- Rheumatoid Arthritis, Systemic Lupus, Sjögren Syndrome, Systemic Vasculitis
- Trial name
- IPS-BOOSTER (NCT03762824)
- Testing
- 13-valent pneumococcal conjugate vaccine, 23-valent pneumococcal polysaccharide vaccine
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Region Skane
Inflammation, Sjogren's Syndrome
Superb Microvascular Imaging Ultrasonography of Lacrimal Gland in Patients With Sjögren Syndrome
A prospective study will be conducted to evaluate inflammatory activity in lacrimal glands due to Sjögren's syndrome on Superb Microvascular Imaging (SMI), gray scale ultrasound (US), color Doppler US and Power Doppler US.
- Conditions
- Inflammation, Sjogren's Syndrome, Gland; Inflammation
- Trial name
- SMI (NCT05689749)
- Testing
- Superb Microvascular Imaging (SMI) (Toshiba)
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Primary Sjögren Syndrome
Effects of Primary Sjögren's Syndrome on Female Genitalia and Sexual Functions
A total of 68 women with pSS and 135 healthy female patients were included in the study. All women in the study and control groups were evaluated gynecologically, and genital findings during the examination and variables related…
- Trial name
- NCT04816370
- Testing
- FSFI
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ankara Education and Research Hospital
Primary Sjögren's Syndrome
Primary Sjögren Syndrome
Primary Sjögren syndrome (pSS) is an inflammatory, autoimmune, multiorgan disease often involving the central and peripheral nervous systems.
- Trial name
- NeuroSenSS (NCT01989819)
- Testing
- skin biopsy
- Where
- 7 sites in France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Sjogren's Syndrome
Immune Profile of Saliva and Serum of Patients With Primary Sjögren´s Syndrome
Primary Sjögren's syndrome (pSS) is a chronic systemic inflammatory disease, which mainly affects the lacrimal and salivary glands, leading to sicca syndrome.
- Trial name
- pSS (NCT03711214)
- Testing
- Periodontal scaling
- Where
- 3 sites in Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Primary Sjögren's Syndrome (pSS)
Artificial Intelligence Based Models for Primary Sjögren's Syndrome Diagnosis
The goal of this observational study is to develop and validate artificial intelligence (AI)-driven models for improving the diagnosis of Primary Sjögren's Syndrome (PSS) using routine laboratory test data.
- Trial name
- NCT06982482
- Where
- China
- Volunteers
- 27,432 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Small Fiber Neuropathy, Primary Sjögren Syndrome
Cutaneous Silent Period Assessment in Primary Sjögren's Syndrome
Primary Sjögren's syndrome (pSS) is a chronic, immune-mediated inflammatory disease mainly characterized by exocrine gland involvement.
- Trial name
- NCT05380804
- Testing
- cutaneous silent period (CSP) measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Marmara University
Sjogren's Syndrome, Dry Eye Syndromes
Salivary Conductivity Screening for Dry Eye Disease and Sjögren's Syndrome
Dry eye disease, or keratoconjunctivitis sicca, is one of the most common diseases encountered at ophthalmologic clinics. Patient with dry eye disease commonly presented foreign body sensation, red eye, blurred vision, etc.
- Trial name
- NCT06406933
- Testing
- Carbomer Gel/Jelly
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Systemic Lupus Erythematosus
The Therapeutic Value and Mechanism of Recombinant Human Interleukin-2 on Children With Rheumatic Diseases
The study aims to explore the therapeutic value and mechanism of Interleukin-2 on children with rheumatic diseases (Systemic Lupus Erythematosus, Primary Sjögren Syndrome, Juvenile Idiopathic Arthritis).
- Trial name
- SLE，pSS，JIA (NCT04397107)
- Testing
- IL-2
- Where
- China
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Jilin University
Primary Sjögren Syndrome
Neurotrophins Implications in Primary Sjögren Syndrome
Neurotrophins (NTs) constitute a family of growth factors, which regulated differentiation, proliferation, and survival of both neuronal cells and astrocytes.
- Trial name
- Neuro-SGSp (NCT01081184)
- Testing
- blood sample
- Where
- 2 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Dental Implant, Primary Sjögren Syndrome
Prognosis of Dental Implants in Patients With Primary Sjögren's Syndrome
Primary Sjögren's Syndrome (PSS) is a chronic autoimmune inflammatory disease primarily involving the salivary and lacrimal glands. Few data exist regarding survival and success rate of dental implants in patients with PSS.
- Trial name
- NCT04960605
- Testing
- Dental implants
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen