Clinical trials: Skeletal Muscle Physiology
Cryotherapy Effect
Cold Therapy in the Treatment of Exercise-induced Muscle Damage
Subjects were randomly placed in five groups: (1) single exposure at 5°C in cold water immersion, (2) single exposure at 15°C in cold water immersion, (3) multiple exposures at 10°C in cold water immersion, (4) whole body…
- Trial name
- NCT02341612
- Testing
- single exposure at 5°C in CWI, single exposure at 15°C in CWI, multiple exposures at 10°C in CWI
- Where
- Brazil
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Hypertrophy, Physiologic Hypertrophy
Beta2-adrenergic Agonism and Muscle Remodelling
The study aims to investigate gender-specific adaptations to beta2-adrenoceptor stimulation with selective short- and long-acting beta2-agonist with emphasis on skeletal muscle in relation to performance enhancing effects and…
- Conditions
- Hypertrophy, Physiologic Hypertrophy, Physical Activity
- Trial name
- NCT03565302
- Testing
- Formoterol, Terbutaline
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Sarcopenia
Effect of Carnitine Supplementation and Resistance Training on Skeletal Muscle Function
The primary aim of the current research project is to explore whether nutritional supplementation and resistance training might be combined to produce synergistic effects in the prevention of muscle loss during aging.
- Trial name
- NCT03907592
- Testing
- L-carnitine supplementation, Leucine supplementation, Resistance training
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Impaired Mitochondrial Function, Muscle Performance
Assessing the Effects of Increased Mitochondrial Function Exercise Training on Muscle Performance
As people grow older skeletal muscle gradually becomes smaller and weaker, causing reduced mobility and quality of life. To understand and reverse this negative process investigators need to find new ways of improving the ability…
- Trial name
- Rejuvenate2 (NCT03325491)
- Testing
- Acipimox
- Where
- United Kingdom
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Exeter
HIV/AIDS
People Living With HIV/AIDS, Nitrate, Endotelial Function, Arterial Stiffness and Skeletal Muscle Oxygenation
Administration of antiretroviral therapy has brought benefits for infective human immunodeficiency virus-1 (HIV-1)-patients, reducing the number of AIDS-related morbidity and mortality.
- Trial name
- NCT03485248
- Testing
- Beetroot Juice
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Heart Failure
Impact of Heart Failure on Calcium Homeostasis and Mitochondrial Function in Human Skeletal Muscle
The aim of this project is to investigate the impact of heart failure (HF) on calcium homeostasis, mitochondrial function and oxidative stress in human skeletal muscle, before and after exercise training.
- Trial name
- Calcicard (NCT01014611)
- Where
- France
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Type 1 Diabetes
Type 1 Diabetes, Endothelin, and Skeletal Muscle Mitochondrial Dysfunction: The Role of Sirtuin-1
The proposed study is designed to test the hypothesis that treatment of resveratrol for 12 weeks will improve both endothelin-B receptor (aim 1) and skeletal muscle mitochondrial function (aim 2) in people with type 1 diabetes.
- Trial name
- T-St1M (NCT04449198)
- Testing
- Resveratrol
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Augusta University
Sarcopenia
Carnitine Supplementation and Skeletal Muscle Function
Research project objectives The primary aim of the current research project is to use carnitine supplementation as the anti-inflammatory intervention for exploring the relationship between inflammation and associated with aging…
- Trial name
- NCT02692235
- Testing
- carnitine
- Where
- Poland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Sarcopenia
Effect of Exercise and Protein Supplementation on Muscle Function in Patients With Hemodialysis
Sarcopenia can be easily observed in patients with hemodialysis. However, there were few studies on the precise concept and diagnostic criteria for sarcopenia in patients with hemodialysis.
- Trial name
- NCT04927208
- Testing
- exercise and nutritional support
- Where
- South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Chungnam National University Hospital