Clinical trials: Skin Aging
Skin Aging
Evaluation of the Safety and Effectiveness of the Investigational Product in Improvement of the Appearance of Wrinkles and General Aspect of the Skin
The study investigates the safety and effectiveness of SILIMED® brand MEDGEL ANTIAGE with indication for improvement of the appearance of wrinkles and general aspects of the skin.
- Trial name
- NCT05997654
- Testing
- MEDGEL ANTIAGE
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Silimed Industria de Implantes Ltda
Aged Skin
An Efficacy and Safety Study Evaluating Treatment Sessions of Restylane Skinboosters Vital Lidocaine in the Face
A randomised, multi-centre, parallel-group efficacy and safety study evaluating two and three initial treatment sessions of Restylane Skinboosters Vital Lidocaine in the face.
- Trial name
- NCT02403986
- Testing
- Restylane Vital Skinboosters Lidocaine
- Where
- Germany
- Volunteers
- 53 people
- Sponsor
- Galderma R&D
Skin Aging, Skin Wrinkling
Evaluation of Safety and Efficacy of Using Imagine™ Computerized Radiofrequency System for Skin Tightening
Skin aging is a multifactorial process involving the 3 layers of the skin: Epidermis, dermis and hypodermis. Skin aging process involves among others: skin roughness (epidermis), skin dyschromia (epidermis, dermis), wrinkles and…
- Trial name
- NCT00945685
- Testing
- Endymion Imagine™ System for Skin Tightening
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Endymion Medical Ltd
Skin Aging
Efficacy and Safety Study of Botulinum Toxin Type A for Moderate to Severe Crow's Feet Lines
This study will evaluate the efficacy and safety of botulinum toxin type A compared to placebo control for the treatment of moderate to severe crow's feet lines.
- Trial name
- RADIANT (NCT01776606)
- Testing
- Botulinum Toxin Type A
- Where
- United States
- Volunteers
- 247 people
- Sponsor
- Revance Therapeutics, Inc.
Skin Aging
Multicenter, Prospective Study to Determine the Performance and Safety of the New M-HA30 Architect Device on the Quality of the Skin: HEBE8 Study
For skin rejuvenation the targeted population does not present a specific pathology. Aesthetic procedures are requested by the patient to improve appearance, look younger and feel better.
- Trial name
- HEBE8 (NCT07007351)
- Testing
- Intradermal injection
- Where
- France
- Volunteers
- 285 people
- Sponsor
- Laboratoires FILLMED
Skin Aging, Skin Quality
AnteAGE Exosomes and PEARL Multiplier With Microneedling for Facial Skin Quality
This exploratory clinical study evaluated changes in facial skin quality following a series of mechanical microneedling treatments combined with topical AnteAGE Exosomes and PEARL Multiplier and a standardized AnteAGE homecare…
- Trial name
- NCT07849205
- Testing
- Mechanical microneedling, AnteAGE Exosomes and PEARL Multiplier, AnteAGE Homecare Regimen
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cellese Inc.
Anti-aging
Anti-aging Repairing Serum: Efficacy and Tolerability Study
The study aimed to evaluate the effectiveness and tolerability of a dermocosmetic serum containing hyaluronic acid, vitamin B5, madecassoside and La Roche-Posay Thermal Spring Water in reducing skin aging signs.
- Trial name
- NCT06059274
- Testing
- Topical serum
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Healthy Subjects, Healthy Adult
Development of a Clinical Photographic Atlas for Skin Aging Based on the Characterization of Facial Dermal Collagen Using LC-OCT Technology
This is a single-center, single visit study conducted in healthy female subjects, aged 20 to 75 years inclusive meeting specific inclusion/exclusion criteria.
- Trial name
- NCT07409675
- Testing
- LC-OCT acquisitions on the forehead, Perform standardized photographs using ColorFace, LC-OCT acquisitions on forehead
- Where
- France
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Vichy Laboratoires
Anti-Aging, Skin Aging
Evaluation of the Anti-aging Efficacy of Four Skin Health Products
The purpose of this study is to assess the anti-wrinkle and anti-aging efficacy of four different cosmetic products compared to an untreated control (split-face study design)
- Trial name
- NCT05473832
- Testing
- Day Cream cosmetic product compared to untreated side, Night cream cosmetic product compared to untreated side, Eye cream cosmetic product compared to untreated side
- Where
- Germany
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Wrinkle
Study to Identify if Saie Beauty's Under Eye Concealer Works to Improve Under-Eye Skin Appearance and Reduce Imperfections
Saie Beauty has developed 'Hydrabeam Sheer Brightening Under Eye Concealer' that is specifically designed for improving under-eye skin health.
- Trial name
- NCT05231681
- Testing
- Saie Beauty's Hydrabeam Sheer Brightening Under Eye Concealer
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Saie Beauty
Skin Aging, Dry Skin
Efficacy and Safety of NP-2007 on Skin Health
The objective of this study is to evaluate the efficacy and safety of Small-molecular-weight deer antler collagen (NP-2007) on skin health, including skin hydration, transepidermal water loss (TEWL), elasticity, and eye wrinkles.
- Trial name
- NCT07486414
- Testing
- NP-2007
- Where
- South Korea
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Hanpoong Nature Pharm Co., Ltd.
Healthy Volunteers
Evaluation of the Anti-aging Efficacy of Two Dietary Supplements
The study is aimed to assess the efficacy of two dietary supplements composed of berry extracts in reducing skin aging signs and improving skin complexion.
- Trial name
- NCT06032598
- Testing
- Berry extract 1, Berry extract 2
- Where
- Italy
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Seppic
Aging Problems, Pigmentation
16-Week Randomized Split-Face Efficacy Study of Cosmetic Formulations in Photoaged Pigmented Skin Subjects
The objective of this study is to determine the efficacy of seven different formulations currently marketed and commercially available cosmetic products on skin tone evenness, post-inflammatory hyperpigmentation, and discrete…
- Trial name
- NCT05160103
- Testing
- Cosmetic Formulations
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Avon Products, Inc.
Skin Aging, Wrinkles
Astaxanthin (2 mg) + Lycopene (1.8 mg) + D-Alpha-Tocopherol (10 IU) For The Treatment Of Skin Aging
The purpose of this study is to determine the clinical efficacy of a combination of Astaxanthin (2 mg), Lycopene (1.8 mg), and d-alpha-Tocopherol (10 IU) in terms of its skin anti-aging properties.
- Trial name
- NCT03460860
- Testing
- Astaxanthin (2mg)+Lycopene (1.8mg)+D-Alpha-Tocopherol (10IU)
- Where
- Philippines
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- United Laboratories
Skin Ageing
Skin Mitochondrial Protection by R0090948A Active
The study intends to evaluate the skin longevity through mitochondria protection efficacy of cosmetic products after 3 months of product application, under UV exposures or not, followed by skin biopsies.
- Trial name
- NCT07853027
- Testing
- Skin biopsy
- Volunteers
- 13 people
- Sponsor
- L'Oreal
Hyperpigmentation, Photodamaged Skin
A Multi-Center, Open-label Study Evaluate the Efficacy and Tolerability of a Dual Skincare Regimen Treatment for Facial Hyperpigmentation and Photodamaged Skin in Patients Exposed to Extrinsic Factors of Aging
This open-label, multi-center clinical trial was conducted to evaluate the dual skincare regimen of vitamin C serum and moisturizing sunscreen SPF 45 to improve facial hyperpigmentation and photodamage after 12 weeks of twice…
- Conditions
- Hyperpigmentation, Photodamaged Skin, Wrinkle, Fine Lines
- Trial name
- NCT05423873
- Testing
- Gentle Cleansing Lotion, Revision Skincare
- Where
- 3 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Skin Hydration, Skin Aging
Clinical Trial to Evaluate the Efficacy of Skin Products to Improve Skin Quality and Health
This clinical trial evaluates the efficacy of three skincare products-Truology A2 (0.2% Retinaldehyde Serum), Truology C-Boost, and Truology Barrier Restore-in improving skin quality and health.
- Trial name
- NCT06853899
- Testing
- Truology A2, Truology C-Boost, Truology Barrier Restore
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Truology
Radiation Tolerance, Skin Aging
Skin Safety Profile of Different Exposure to the Light Emitting Diode (LED) in Healthy Subjects
Photomodulation is a process which manipulates or regulates cell activity using light sources without thermal effect. Different studies have investigated the use of non-thermal low dose light emitting diode (LED) array for…
- Conditions
- Radiation Tolerance, Skin Aging, Rhytids
- Trial name
- NCT00818311
- Testing
- LED GentleWaves®
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Skin Aging
Evaluation of the Anti-aging Efficacy of a Novel Skin Health Product
The aim of this study is to investigate the effect of cosmetic products with two different concentrations of the active on skin aging and in acting on the mitochondrial health of skin in comparison to a placebo product.
- Trial name
- NCT05300984
- Testing
- Topical Cream with 0.5% Active, Topical Cream with 1% Active
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Skin Aging
Patient Satisfaction With Treatment of BOTOX® Cosmetic for the Temporary Correction of Moderate to Severe Glabellar Lines
This study evaluates the patient satisfaction and onset of effect following treatment with botulinum toxin Type A in the treatment of glabellar rhytids (frown lines)
- Trial name
- NCT00856414
- Testing
- botulinum toxin Type A
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Allergan