Clinical trials: Skin Burns
Burns, Second Degree Burn
4-Aminopyridine to Treat Skin Burns
Many patients suffer from traumatic burns and current treatments do not increase the regenerative potential of either skin grafts or the remaining uninjured skin.
- Conditions
- Burns, Second Degree Burn, Wounds and Injuries
- Trial name
- NCT06596434
- Testing
- Drug: 4-Aminopyridine
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- John Elfar
Healthy Adults
Effect of Orally Delivered Phytochemicals on Aging and Inflammation in the Skin
The objective is to determine, in a small number of participants, the protective effects of UV-induced skin erythema (reddening or "sunburn") following oral administration of sulforaphane, curcumin, or a combination of the two…
- Trial name
- NCT03289832
- Testing
- Crucera-SGS, Meriva 500-SF
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Burns
A Prospective, Descriptive Cohort Study With Prontosan® Wound Gel X in Partial and Full Thickness Burns Requiring Split Thickness Skin Grafts
The purpose of this study is to evaluate the healing of split thickness skin grafts when treated with Prontosan® Wound Gel X in patients with partial and full thickness skin burns.
- Trial name
- NCT01534858
- Testing
- Prontosan Wound Gel X
- Where
- 3 sites in Germany
- Volunteers
- 51 people
- Sponsor
- B. Braun Ltd. Centre of Excellence Infection Control
Breast Neoplasms
A Clinical Trial to Reduce Skin Burn Induced by Breast Radiotherapy Using Intensity Modulated Radiation Therapy (IMRT)
The purpose of this study is to determine whether the use of a 3D missing tissue compensation radiation technique during a standard adjuvant breast radiotherapy delivering a dose of 50Gy in 25 treatments could reduce…
- Trial name
- NCT00187343
- Testing
- Breast IMRT
- Where
- 2 sites in Canada
- Volunteers
- 340 people
- Sponsor
- Sunnybrook Health Sciences Centre
Burns
Platelet-Rich Plasma (PRP) in Reconstructive Surgery on Children With Retractable Burn Sequelae on Extremities
Does the addition of Platelet-Rich Plasma (PRP) to release of burn contractures and skin graft on the limbs of children with retractable burn sequelae reduce the initial time of the compressive treatment and maintain or lower the…
- Trial name
- NCT00858442
- Testing
- With PRP
- Where
- Chile
- Volunteers
- 44 people
- Sponsor
- Corporation for the Aid of Burned Children
Burn
Microbiota in Children With Severe Burn Injury
The research protocol consists of taking aliquots of biological specimens from skin swabs, nasopharyngeal swabs, and fecal swabs.
- Trial name
- MIBUS (NCT07098377)
- Testing
- nasopharyngeal swab for biological sample analysis
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Burns, Wound Healing
Efficacy Study of a Bioelectric Dressing to Treat Skin Graft Donor Site Wounds
The purpose of this study is to determine whether the use of a bioelectric wound dressing is effective in the healing of skin graft donor site wounds.
- Trial name
- NCT01061502
- Testing
- Procellera (Bioelectric Wound Dressing), Opsite (Transparent Adhesive Dressing)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Vomaris Innovations
Hypertrophic Scars
Laser Induced Bioengineered Remodeling of Thermally Injured Skin Trial
This study will evaluate the efficacy of pulsed dye laser (PDL) and carbon dioxide (CO2) laser in conjunction with usual care (MED) for the treatment of hypertrophic burn scars and will determine the optimal sequence and timing…
- Trial name
- LIBERTI (NCT02655211)
- Testing
- CO2 laser treatment, PDL laser treatment, Usual care
- Sponsor
- University of North Carolina, Chapel Hill
Skin Scars, Post-burn Scars
Exploratory Study to Evaluate the Efficacy of the Cosmetic Product RV3895A on Re-epidermised Scars Following Burns and Surgical Stitches in Adults, Adolescents and Children Over a 6-month Follow-up Period
This study is exploratory, non-comparative and open-label, conducted in France. It aims to provide insights into the effectiveness and safety of RV3895A - RY1774, potentially benefiting participants by improving scar appearance…
- Conditions
- Skin Scars, Post-burn Scars, Post-surgical-stitches Scars
- Trial name
- NCT07020507
- Testing
- Product gel RV3895A
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
Deep Full-thickness Burn Injury (Disorder)
Evaluation of Safety and Efficacy of realSKIN® (Skin Xenotransplant) for Complete Closure of Severe Burn Wounds
This is a Phase 1/2, Open-label, Multi-center, Clinical Trial to evaluate the safety, tolerability, and efficacy of realSKIN® to provide complete wound closure of severe and extensive deep-partial and full-thickness burn wounds.
- Trial name
- NCT03695939
- Testing
- realSKIN (skin xenotransplant), Human Cadaver Allograft
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- XenoTherapeutics, Inc.
Burn Degree Second, Burn Degree Third
Biological Skin Graft With Keratinocyte-stem Cell Co-cultre for Burn Patients
The goal of this clinical trial is to test whether artificial skin graft can substitute autologous skin graft in current burn treatment.
- Trial name
- NCT05652816
- Testing
- Split-thickness skin graft, Artificial skin graft, Artificial skin graft co-culture
- Where
- Indonesia
- Volunteers
- 20 people
- Sponsor
- Universitas Indonesia
Sunburn
A Randomized Controlled Trial to Test the Effects Oxytocin and Vibration Have on Heat Pain Threshold After UV-B Burn
This study aims to answer the question: Does oxytocin increase the pain threshold on thermal heat pain in the presence of vibration on an area of skin exposed to a mild sunburn?
- Trial name
- NCT06651476
- Testing
- oxytocin
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Burns, Scars
The Technique of Skin Stretching for Acute Burn Treatment and Scar Reconstruction
Objective: A randomized controlled trial is performed to evaluate the clinical effectiveness of the skin stretching technique for two categories: 1.
- Trial name
- NCT00609908
- Testing
- Split skin graft, skin stretching device, serial excision
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Association of Dutch Burn Centres
Burn Scar, Hypertrophic Scar
Characterization of Dyschromic Hypertrophic Scar
Currently, there are limited prevention or treatments available for dyschromia in burn hypertrophic scars (HTSs). The limited available techniques involve transferring melanocytes from unaffected areas to the scar to adjust…
- Conditions
- Burn Scar, Hypertrophic Scar, Hyperpigmentation, Hypopigmented Scar
- Trial name
- NCT04619589
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Medstar Health Research Institute
Burn Injury
Effects of Non-Invasive Vagus Nerve Stimulation in Adolescent Burn Patients
This study will evaluate the effects of non-invasive vagus nerve stimulation in adolescents aged 12 to 18 years who have burn injuries.
- Trial name
- NCT07566923
- Testing
- Non-Invasive Vagus Nerve Stimulation, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fenerbahce University
Burn Scar, Skin Graft Scar
Fractional Ablative Laser Treatment for Skin Grafts
Doctors and patients refer to all areas of skin changes from burn injury as burn scars. However, different areas of scars from burns can be treated differently.
- Trial name
- NCT04176705
- Testing
- Lidocaine Cream, Triamcinolone Acetonide Cream, Fractional Ablative Laser
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Wake Forest University Health Sciences
Acquired Breast Deformity, Breast Cancer
Endoscopic Assisted Latissimus Dorsi Musculocutaneous Flap for Breast Reconstruction
This prospective single-arm case series evaluates the feasibility, safety, and clinical outcomes of endoscopic-assisted latissimus dorsi musculocutaneous flap harvest for breast reconstruction.
- Conditions
- Acquired Breast Deformity, Breast Cancer, Post Burn Breast Deformities
- Trial name
- NCT07691294
- Testing
- Endoscopic-Assisted Latissimus Dorsi Musculocutaneous Flap Harvest
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Kasr El Aini Hospital
Burns, Postoperative Pain
Liposomal Bupivicaine for Skin Graft Donor Sites in Burn Patients
Burn injuries are painful to patients and the sources of pain result from many areas including: the injury itself, wound care, and surgery.
- Trial name
- NCT03705637
- Testing
- Exparel
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital
Skin Abnormalities
Moisturizing Effect of Two Dexpanthenol Formulations
The study focuses to prove the equivalent moisturizing effect of two different Dexpanthenol formulations
- Trial name
- NCT00839280
- Testing
- Dexpanthenol foam spray, new formulation, Dexpanthenol foam spray, old formulation
- Where
- France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Bayer
Burns
Pediatric Burn Treatment Using Tilapia Skin as a Xenograft for Superficial-Partial Thickness Wounds
This study aims to evaluate the efficacy of Nile tilapia skin as a xenograft for the treatment of partial-thickness burn wounds in children.
- Trial name
- NCT04391582
- Testing
- Tilapia skin, silver sulfadiazine cream 1%
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara