Clinical trials: Skin Cancers - Basal Cell Carcinoma
Carcinoma, Basal Cell
DMSO-PDT of BCC - A 6 Year Follow up
The purpose of this study is to registrate long time clinical and histological treatment response of basal cell carcinoma (BCC) lesions treated with one or two procedures of dimethylsulfoxide supported 5-aminolaevulinic acid…
- Trial name
- NCT00218829
- Volunteers
- 44 people
- Sponsor
- Norwegian University of Science and Technology
Superficial Basal Cell Carcinoma
PEP005 Gel - Evaluation of the Safety and Efficacy of Ingenol Mebutate Gel on a Superficial Basal Cell Carcinoma on the Trunk or Extremities
This study is primarily designed to investigate whether treatment, once daily for up to three consecutive days, with PEP005 (ingenol mebutate) Gel, 0.05% will be safe and tolerable in patients with superficial Basal Cell…
- Trial name
- NCT01325688
- Testing
- PEP005 (ingenol mebutate) Gel, 0.05%, Aluminium disk, OpSite(TM) disk
- Where
- 7 sites in Australia
- Volunteers
- 75 people
- Sponsor
- Peplin
Bladder Cancer, Breast Cancer
Physician-Initiated Stop-Smoking Program for Patients Receiving Treatment for Early-Stage Cancer
RATIONALE: Physician-initiated smoking cessation strategies may be effective in getting early-stage cancer patients to quit smoking.
- Conditions
- Bladder Cancer, Breast Cancer, Colorectal Cancer, Head and Neck Cancer
- Trial name
- NCT00002520
- Testing
- nicotine, Usual Care
- Where
- United States
- Volunteers
- 434 people
- Sponsor
- Eastern Cooperative Oncology Group
Head and Neck Cancer, Infection
Fluconazole in Preventing Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer
RATIONALE: Giving fluconazole may be effective in preventing or controlling mucositis caused by radiation therapy to the head and neck.
- Conditions
- Head and Neck Cancer, Infection, Oral Complications
- Trial name
- NCT00002533
- Testing
- fluconazole, radiation therapy
- Where
- United States
- Sponsor
- University of Miami
Basal Cell Carcinoma
Video-Based Treatment Options for Basal Cell Carcinoma
The purpose of this study is to determine if presenting treatment options to basal cell carcinoma patients in video format will improve efficiency and allow patients to receive consistent, comprehensive, visually-depicted…
- Trial name
- NCT02158650
- Testing
- Video-Based Informed Consent
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Emory University
Basal Cell Carcinoma
The Role of Melanocyte in Basal Cell Carcinoma
Basal cell carcinoma (BCC) is the most frequent neoplasia worldwide. There are more than 30 histopathologic subtypes, however the nodular subtype is the most common.
- Trial name
- NCT02576769
- Testing
- No intervention
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Cutaneous Squamous Cell Carcinoma, Basal Cell Carcinoma
Intralesional Cemiplimab for Adult Patients With Cutaneous Squamous Cell Carcinoma or Basal Cell Carcinoma
This study is researching an experimental drug called cemiplimab. The study is focused on Cutaneous Squamous Cell Carcinoma (CSCC) and Basal Cell Carcinoma (BCC).
- Trial name
- NCT03889912
- Testing
- Cemiplimab
- Where
- 18 sites in United States, Australia and 1 more
- Volunteers
- 97 people
- Sponsor
- Regeneron Pharmaceuticals
Basal Cell Carcinoma
Optical Coherence Tomography Guided C&D
The purpose of the study is to identify the presence of residual superficial and nodular basal cell carcinoma (BCC) status-post curettage and desiccation (C\&D) by using optical coherence tomography (OCT).
- Trial name
- NCT04510727
- Testing
- Optical Coherence Tomography (OCT), Curettage & Desiccation (C&D) Procedure
- Where
- United States
- Sponsor
- University of Miami
Cutaneous Squamous Cell Carcinoma (CSCC), Basal Cell Carcinoma (BCC)
Flash Radiotherapy for Skin Cancer
The goal of this clinical investigation is to describe and compare the toxicity and efficacy of an experimental radiotherapy, named FLASH therapy, to conventional radiotherapy for subjects suffering from localized Cutaneous…
- Trial name
- LANCE (NCT07455331)
- Testing
- FLASH radiotherapy, Conventional radiotherapy
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Jules Bordet Institute
Basal Cell Carcinoma, Squamous Cell Carcinoma
HRQoL Keratinocyte Carcinomas
Rationale: Keratinocyte skin cancer is known to influence the HRQoL in a specific way. Derived utility values are required for cost-effectiveness analyses of new interventions.
- Conditions
- Basal Cell Carcinoma, Squamous Cell Carcinoma, Actinic Keratoses
- Trial name
- NCT04814953
- Testing
- questionnaires
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 2,400 people
- Sponsor
- University Hospital, Ghent
Solid Tumor, Adult, Solid Tumor
R-5780-01 In Combination With PD-1 Checkpoint Inhibitors (Checkpoint Protein on Immune Cells Called T Cells) in Patients With Solid Tumors
The goal of this study is determine the safety and tolerability of orally taken probiotic (R-5780) in patients currently on a PD-1 Pathway Checkpoint Inhibitor (checkpoint protein on immune cells called T cells) with Solid Tumors.
- Conditions
- Solid Tumor, Adult, Solid Tumor, Melanoma, Basal Cell Cancer
- Trial name
- NCT06398418
- Testing
- R-5780
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- Rise Therapeutics LLC
Basal Cell Carcinoma of the Skin, Recurrent Skin Cancer
Arsenic Trioxide in Treating Patients With Basal Cell Carcinoma
This pilot clinical trial studies arsenic trioxide in treating patients with basal cell carcinoma. Drugs used in chemotherapy, such as arsenic trioxide, work in different ways to stop the growth of tumor cells, either by killing…
- Trial name
- ATO (NCT01791894)
- Testing
- arsenic trioxide
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Stanford University
Basal Cell Carcinoma
Placebo Microneedles in Healthy Volunteers (Part I) and Efficacy/Safety of Doxorubicin Microneedles in Basal Cell Cancer Subjects (Part II)
Part I is designed as a study of P-MNA application in healthy human volunteers. The goal of Part I is to determine several factors possibly affecting the rate and extent of microneedle array dissolution, such as anatomic…
- Trial name
- NCT04928222
- Testing
- Doxorubicin-containing MNA
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- SkinJect, Inc.
Anal Cancer, Cervical Cancer
Vaccine Therapy in Treating Patients With Advanced or Recurrent Cancer
RATIONALE: Vaccines made from certain human papillomaviruses may be able to help the body to kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of human papillomavirus vaccine therapy in treating patients…
- Conditions
- Anal Cancer, Cervical Cancer, Esophageal Cancer, Head and Neck Cancer
- Trial name
- NCT00019110
- Testing
- human papillomavirus 16 E7 peptide, synthetic human papillomavirus 16 E6 peptide
- Where
- 6 sites in United States
- Sponsor
- National Cancer Institute (NCI)
Non-melanomatous Skin Cancer, Precancerous/Nonmalignant Condition
Eflornithine With or Without Triamcinolone in Preventing Nonmelanoma Skin Cancer in Patients With Actinic Keratosis
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. Eflornithine with or without triamcinolone may be effective in preventing nonmelanoma skin cancer.
- Trial name
- NCT00021294
- Testing
- eflornithine, triamcinolone
- Where
- United States
- Sponsor
- University of Arizona
Basal Cell Carcinoma of Skin, Optical Coherence Tomography (OCT)
Real-world Evaluation of the Implementation of LC-OCT in Daily Clinical Practice
Basal cell carcinoma (BCC) is the most common skin cancer in the Netherlands, with incidence rates continuing to rise. The current diagnostic standard combines clinical evaluation and dermoscopy, while biopsy followed by…
- Conditions
- Basal Cell Carcinoma of Skin, Optical Coherence Tomography (OCT), Neoplasms, Neoplasms, Basal Cell
- Trial name
- RELI (NCT07501780)
- Where
- Netherlands
- Volunteers
- 297 people
- Sponsor
- Maastricht University Medical Center
Non-melanomatous Skin Cancer
Photodynamic Therapy Using Aminolevulinic Acid in Treating Patients With Skin Cancer
RATIONALE: Photodynamic therapy uses a drug that becomes active when it is exposed to a certain kind of light. When the drug is active, tumor cells are killed. This may be an effective treatment against skin cancer.
- Trial name
- NCT00747903
- Testing
- aminolevulinic acid hydrochloride
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Laser and Skin Surgery Center of New York
Basal Cell Carcinoma of the Skin
Evaluation of the Efficiency and Economic Impact of LC-OCT (Line-field Confocal Optical Coherence Tomography) for the Diagnosis and Management of Basal Cell Carcinomas
This is a comparative, randomized, prospective, multicenter clinical investigation aimed at evaluating the efficiency and economic impact of LC-OCT (Line-field Confocal Optical Coherence Tomography) for the diagnosis and…
- Trial name
- ECOBASO (NCT06271603)
- Testing
- diagnosis based on deepLive™ LC-OCT device, diagnosis based on skin biopsy
- Where
- France
- Volunteers
- 704 people
- Sponsor
- Damae Medical
Superficial Basal Cell Carcinoma
Superficial Basal Cell Carcinoma Treatment With Topical Photodynamic Therapy With Fractionated 5-aminolevulinic Acid 20% Versus Two Stage Methylaminolevulinate
Skin cancer is the most common cancer in Caucasians, and a basal cell carcinoma (BCC) being the most common skin cancer with around 44,000 new tumours per year, and its incidence is still rising.
- Trial name
- NCT01491711
- Testing
- Methylaminolevulinate PDT in 2 sessions, Fractionated 5-aminolevulinic acid hydrochloride 20% gel PDT
- Where
- 3 sites in Netherlands
- Volunteers
- 162 people
- Sponsor
- Maastricht University Medical Center
Basal Cell Carcinoma
New Imaging Procedures and Therapeutic Approach in Basal Cell Carcinoma Management
The aim of this study is to show that the Nd:YAG laser could be a promising alternative treatment option in the management of low-risk basal cell carcinomas with similar high efficacy rates to surgery, and low recurrence rates…
- Trial name
- NCT05324202
- Testing
- Cynosure Cynergy Nd:YAG Laser 1064nm
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dr. Stephanie Geisler