Clinical trials: Skin Closure
Cesarean Section Wound
Staples Versus Dermabond for Closure of the Skin After Cesarean Section
Two of the more frequently used options for skin closure following a cesarean delivery include staples or sutures (stitches). Another method of closure is Dermabond- liquid skin adhesive.
- Trial name
- NCT01261715
- Testing
- Dermabond- liquid skin adhesive
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
Bone Diseases, Infectious
Pressure Ulcer-associated Osteomyelitis: Evaluation of a Two-stage Surgical Strategy With Prolonged Antimicrobial Therapy
Pressure ulcer represents a frequent clinical condition in patient with spinal cord injury or after prolonged Intensive Care Unit (ICU) stay.
- Trial name
- NCT03010293
- Where
- France
- Volunteers
- 61 people
- Sponsor
- Hospices Civils de Lyon
Venous Leg, Venous Leg Ulcer (VLU)
Evaluating the Durability of Closure for Venous Leg Ulcers
The goal of this observational study is to determine the durability of closure for venous leg ulcer subjects that achieved closure in the THOR trial.
- Conditions
- Venous Leg, Venous Leg Ulcer (VLU), Venous Leg Ulcer, Venous Ulcer
- Trial name
- THORSDOTTIR (NCT06697925)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Kerecis Ltd.
Cesarean Section
Cosmetic Outcomes With Tissue Adhesive (2-octylcyanoacrylate) or Staples in Repeated Cesarean Section
Recent clinical trials were developed to test the outcomes of skin closure with tissue adhesive, staples and monofilament synthetic suture after cesarean section with Pfannenstiel incision: both clinical outcomes such as blood…
- Trial name
- NCT04302597
- Testing
- Staples, Tissue adhesive
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Università degli Studi dell'Insubria
Benign or Malignant Diseases With Indication for Laparoscopic or Robotic Colorectal Resection
A Study Comparing Skin Adhesive With Staple for Surgical Incision Closure After Laparoscopic / Robotic Bowel Resection
INTRODUCTION Liquid skin adhesive (LSA) has benefits over other closure methods. Especially it is less invasive, quicker to apply, and better in cosmesis.
- Trial name
- NCT04969016
- Testing
- LSA (liquid skin adhesive), stapler
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Yonsei University
Surgical Wound, Tissue Adhesion
Skin Closure With Tissue Adhesives vs. Subcuticular Suture After Robotic Urogynecologic Procedures
To compare skin closure via subcuticular suture versus tissue adhesive (Dermabond) in urogynecological robotic surgeries. The primary outcome is incision cosmesis at the 12 week follow up visit.
- Trial name
- NCT03891004
- Testing
- Subcuticular Skin Closure, Tissue Adhesives
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- St. John Hospital & Medical Center
Skin Closure of Surgical Incisions by Tissue Glue vs Suture
Tissue Glue (Cyanoacrylate) Versus Conventional Suture in Kidney Donors
By means of a prospective, randomised trial the investigators want to examine skin closure in living donors - subjected to laparoscopic, hand-assisted nephrectomy - by tissue glue (Cyanoacrylate (Liquiband)) versus conventional…
- Trial name
- TG-CYANO (NCT01521871)
- Testing
- Skin wound closure by tissue glue, Skin wound closure by conventional suture + dressing
- Where
- Norway
- Volunteers
- 64 people
- Sponsor
- Oslo University Hospital
Appendicitis
Appendicectomy Skin Closure Technique: Changing Paradigms (ASC)
To compare the results associated with two different skin closure techniques in open appendectomy. 200 patients were included after acute appendicitis diagnosis in emergency department.
- Trial name
- ASC (NCT02625987)
- Testing
- Continuous intradermic stitch, Separated stitches
- Volunteers
- 200 people
- Sponsor
- María Valeria Jiménez Baez
Pressure Ulcers Stage III, Pressure Ulcer, Stage IV
Effectiveness of Negative-Pressure Wound Therapy
This study aims to compare the effects of Negative-Pressure Wound Therapy and wet-to-dry dressing on Stages 3 and 4 pressure injuries, and to investigate the consistency of Three-Dimensional Wound Measurement Device findings with…
- Trial name
- NCT04311229
- Testing
- Negative-Pressure Wound Therapy group, contol group
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Inexpensive Closure of Fasciotomy Incisions Without the Need for Skin Grafting
Dermotaxis v/s Loop Suture Technique for Closure of Fasciotomy Wounds : a Study of 50 Cases
The fasciotomy incisions lead to large, unsightly, chronic wounds after surgical intervention. The classic management was split thickness skin grafting but it leads to insensate skin with 23% of people upset by the appearance of…
- Trial name
- NCT02956733
- Testing
- dermotaxis, loop suture technique
- Volunteers
- 50 people
- Sponsor
- Government Medical College, Patiala
Surgical Wound, Wound Heal
Influence of Sun Protection and Linear Repair of Cutaneous Surgical Defects
The purpose of this study is to determine the potential influence of sun protection on the aesthetic outcome of post-surgical scars following the reconstruction of Mohs micrographic surgery defects via linear repair.
- Conditions
- Surgical Wound, Wound Heal, Wound of Skin, Scar
- Trial name
- NCT05074238
- Testing
- Zinc containing suncreen
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Full Thickness Skin Defects
The Safety of a Novel Acellular Dermal Template as Treatment for Burns and Scars
In this study the safety and feasibility of an acellular dermal template (Novomaix), combined with split thickness skin grafts, for use in patients with full thickness skin defects, is tested.
- Trial name
- NCT02164760
- Testing
- Novomaix dermal substitute in combination with STSG
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 13 people
- Sponsor
- Association of Dutch Burn Centres
Sternotomy Closure,Open Heart Surgery
Botulinum Toxin Injection After Sternotomies to Improve Scar Aspect and Impact
Sternotomy scars, which are localized in a high-tension area are often dystrophic, hypertrophic or keloidal, and can be difficult to accept to patients who already endured a heavy intervention with high psychologic impact.
- Trial name
- BotuCiSter (NCT07013240)
- Testing
- Botulinum toxin injection
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Surgical Site Infection (SSI), Ileostomy Closure
Linear Versus Purse String Skin Closure at Loop Ileostomy Reversal.
This study is a randomized controlled trial designed to compare two commonly used skin closure techniques-linear closure and purse-string closure-after loop ileostomy reversal surgery.
- Conditions
- Surgical Site Infection (SSI), Ileostomy Closure, Surgical Technique Comparison
- Trial name
- NCT07573423
- Testing
- Linear Skin Closure, Purse-String Skin Closure
- Where
- Pakistan
- Volunteers
- 252 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Wound
Comparison of Adhesive Latch Device to Subcuticular Skin Closure at the Time of Cesarean Section
The objective of this study was to compare the an adhesive latch device (" Dermaclip") to subcuticular skin closure at the time of cesarean section. Currently, no studies exist comparing these two closure techniques.
- Trial name
- NCT03052647
- Testing
- Dermaclip, Subcuticular suture
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Rubino Ob-Gyn Group
Wound Closure, Dehisced Surgical Wounds
Post Operative Skin Approximation With Cyanoacrylate Based Wound Closure Adhesives
surgical adhesive systems are used to close surgical cuts and simple skin wounds. This system is a non-invasive option, meaning it can be used instead of stitches or staples.
- Trial name
- NCT07613892
- Testing
- Evaluating wound closure products to close larger surgical site incisions, Evaluating wound closure products to close smaller surgical site incisions
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medline Industries
Full Thickness Skin Defects
A Study to Evaluate the Efficacy of an Acellular Dermal Template for the Treatment of Full Thickness Skin Defects
In this study the efficacy of an acellular dermal template (Novomaix), combined with split thickness skin grafts, for use in patients with full thickness skin defects, is tested.
- Trial name
- NCT02373566
- Testing
- Novomaix dermal substitute in combination with STSG
- Where
- 3 sites in Germany, Netherlands and 1 more
- Volunteers
- 11 people
- Sponsor
- Association of Dutch Burn Centres
Macromastia
Study of Prineo (Dermabond Protape) Versus Sutures in Breast Procedures
This is a prospective, controlled, randomized, multi-center clinical study of up to 80 patients with full thickness surgical incisions associated with bi-lateral breast procedures.
- Trial name
- NCT00558246
- Testing
- Dermabond Protape (Prineo), Suture
- Where
- 5 sites in Belgium, Germany and 2 more
- Volunteers
- 79 people
- Sponsor
- Ethicon, Inc.
Cancer
Skin Incision Study - Closure of Skin Incisions in Gynecological Cancer Surgery
The Skin Incision Study evaluates the efficacy of skin closure methods: skin staples and subcuticular sutures at 6 weeks and at 3 months following the operation by measuring cosmesis and pain.
- Trial name
- NCT00107627
- Testing
- Caprosyn subcuticular sutures., Monocryl subcuticular sutures., Skin staples;
- Where
- 2 sites in Australia
- Volunteers
- 90 people
- Sponsor
- Queensland Centre for Gynaecological Cancer
Perineal Tear
Skin Glues Compared to Running Sutures for Perineal Skin Repair After Vaginal Delivery. A Randomized Controlled Trial
The incidence of a perineal tears during labor is 70 to 90%, while in 96% of the cases it's a minor perineal tear (grade 1). In about 3% to 4% the perineal tear is major and involve the external (grade 3) and the internal anal…
- Trial name
- NCT03983343
- Testing
- exofin®
- Where
- Israel
- Volunteers
- 182 people
- Sponsor
- HaEmek Medical Center, Israel