Clinical trials: Skin Closure
Pressure Sore
NPWTi on Closure of Chronic Pressure Sores
The primary objective of this study is to assess the effectiveness of the Negative Pressure Wound Therapy system with instillation therapy (NPWTi) on closure of chronic pressure sores.
- Trial name
- NCT05598398
- Testing
- V.A.C.Ulta™ Negative Pressure Wound Therapy System, Standard of Care (Wet-to-dry dressings)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Northwestern University
Keloid
A Randomized Clinical Study Comparing Two Closure Techniques of Excised Keloids
This investigator initiated study, single-blinded, parallel, randomized study will be conducted in subjects with 2 or more keloids similar in size and duration on a similar area of the body.
- Trial name
- NCT00519493
- Testing
- Suture, Clozex
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Miami
Contusions, Incision
Dermal Wound Closure Using Silkam®
Assessment of performance of Silkam® suture material for skin closure. A prospective, single center, single arm, observational study in daily practice.
- Conditions
- Contusions, Incision, Laceration
- Trial name
- DERMASILK (NCT05225714)
- Where
- Spain
- Volunteers
- 161 people
- Sponsor
- Aesculap AG
Androgenetic Alopecia
Split Wound Comparison of Trichophytic Closure Techniques for Donor Site in Hair Transplantation
This study aim to compare cosmetic results between 3 trichophytic closure techniques for donor site (the trimming of upper, lower and both edge of linear incision) in hair transplantation.
- Trial name
- NCT01655602
- Testing
- Trichophytic closure upper edge trimming, Trichophytic closure lower edge trimming, Trichophytic closure both edge trimming
- Where
- Thailand
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Wound
Study of DERMABOND ProPen in Closure of Colectomy Wounds
2-octylcyanoacrylate (2-OCA) has been used extensively in clinical practice in trauma, plastic surgery, orthopaedic surgery, emergency medicine and paediatrics.
- Trial name
- NCT00978133
- Testing
- Dermabond ProPen (2-octylcyanoacrylate), Skin closure with skin staples
- Where
- Singapore
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Pressure Ulcer (PU), Pressure Ulcers, Bedsores, Decubitus Ulcer
Effectiveness and Costs of Pressure Ulcer Treatment and the Quality of Life of Patients With Pressure Ulcers Receiving Home-Based and Institutional Care
A study aimed at comparing the effectiveness of treatment, costs, and quality of life of patients with pressure ulcers in home care and institutional care.
- Conditions
- Pressure Ulcer (PU), Pressure Ulcers, Bedsores, Decubitus Ulcer, Quality of Life, INSTITUTIONAL CARE
- Trial name
- NCT07763106
- Testing
- residential home care treatment, long-term care treatment
- Where
- 3 sites in Poland
- Volunteers
- 80 people
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Diabetic Foot Ulcer
Comparing Synthetic Hybrid-Scale Fiber Matrix With Standard of Care in Treating Diabetic Foot Ulcers
The purpose of the following prospective, randomized, controlled clinical trial is to compare synthetic hybrid-scale fiber matrix (Restrata®, Acera Surgical, Inc.) with standard of care in treating diabetic foot ulcers in human…
- Trial name
- NCT04918784
- Testing
- Restrata®, Wound Dressing
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Acera Surgical, Inc.
Diabetic Foot Ulcers (DFU), Foot Ulcer Chronic
Evaluating the Durability of Closure for Diabetic Foot Ulcers Following a Randomized, Controlled, Modified Platform Trial.
Prospective long-term follow-up on durability of closure evaluated by photographic and thermal scanning.
- Conditions
- Diabetic Foot Ulcers (DFU), Foot Ulcer Chronic, Ulcer, Diabetic Foot Ulcer
- Trial name
- SCANX (NCT07360418)
- Testing
- Blue Drop Foot Scanner
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Applied Biologics, LLC
Breast Neoplasms
New Formula to Predict the Need for Reconstructive Coverage Following Mastectomy
Mastectomy is a cornerstone operative procedure in breast cancer treatment leaving a raw area behind with possibility of failure of primary closure sometimes with unavailability of facilities of reconstruction.
- Trial name
- NCT04677075
- Testing
- mastectomy
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Zagazig University
Breast Cancer
Dead Space Closure With Quilting Suture Versus Conventional Closure With Drainage
The objective of this study is to compare quilting suture of the "dead space" without drainage of the pectoral area to conventional closure with drainage to prevent post-operative seroma requiring intervention (aspiration or…
- Trial name
- QUISERMAS (NCT02263651)
- Testing
- Quilting suture without drainage, Conventional closure with drainage
- Where
- 6 sites in France
- Volunteers
- 320 people
- Sponsor
- University Hospital, Tours
Diabetic Foot, Ulcer Foot
SDRM® vs. Collagen for Diabetic Foot Ulcers
Supra SDRM® is FDA-cleared as a dressing for treating partial and full-thickness wounds. It is a dermal substitute that provides a barrier and an ECM-like structure to help accelerate wound healing.
- Conditions
- Diabetic Foot, Ulcer Foot, Wound Heal
- Trial name
- NCT05883098
- Testing
- Wound debridement, Wound closure matrix application
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Polymedics Innovations Inc.
Surgical Site Infection (SSI)
Skin Adhesive Plus Intra-cuticular Suture Versus Suture Alone for Cesarean Skin Closure
The goal of this randomized control trial is to compare two skin closure techniques after cesarean section. Both techniques are currently in wide use but no comparison between the two was reasserted yet.
- Trial name
- NCT07483411
- Testing
- Dermabond
- Where
- Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Doron Kabiri
Compare Cosmetic Outcomes of Subcuticular Skin Closure Using Polypropylene and Polyglactin
Polypropylene Versus Polyglactin in Upper Limb Subcuticular Skin Closure
Polypropylene versus Polyglactin in Upper Limb Subcuticular Skin Closure
- Trial name
- NCT07582679
- Testing
- Upper limb wounds subcuticular skin closure with Polypropylene, Upper limb wounds subcuticular skin closure with Polyglactin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Shebin El-Kom Teaching Hospital
Surgical Wound Infections, Colorectal Surgery
Subcuticular Continuous Suture Versus Skin Staples to Reduce Surgical Site Infections in Colorectal Surgery Patients
A comparison of skin closure techniques (standard skin closure with staples versus a continuous (subcuticular) absorbable suture), to determine if this changes the rate of post operative wound infections in elective colorectal…
- Trial name
- NCT02143336
- Testing
- subcuticular suture, Skin staples
- Where
- 2 sites in Spain
- Volunteers
- 400 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Pneumonia, Pneumococcal, Diabetes Mellitus
Text Message-Based Nudges Prior to Primary Care Visits to Increase Care Gap Closure
Primary care visits are a key aspect of clinical care focused on helping patients to close care gaps related to preventive care such as vaccination, diabetes testing, statin therapy and cancer screening.
- Conditions
- Pneumonia, Pneumococcal, Diabetes Mellitus, Breast Cancer, Colorectal Cancer
- Trial name
- NCT05799976
- Testing
- Text message nudge
- Where
- United States
- Volunteers
- 29,334 people, healthy volunteers welcome
- Sponsor
- Mitesh Patel
Wound, Cardiac Arrhythmia
ZIPS Study - Zip Incision aPproximation vs. Suture
ZipLine Medical, Inc. has developed a novel, non-invasive skin closure device called "Zip Surgical Skin Closure" to replace sutures, staples and glue for closure of the skin layer for surgical incisions or laceration repair.
- Trial name
- ZIPS (NCT02213510)
- Testing
- Zip Surgical Skin Closure Device, Standard Suture Closure
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Diego
Foramen Ovale, Patent, Nickel Sensitivity
Investigation of Nickel Sensitization After Percutaneous Implantation of Patent Foramen Ovale Occluder
Percutaneous PFO closure has been established as a first-line therapy for preventing recurrent strokes in selected patients. The devices used for the specific purpose contain and release nickel, which is considered as the most…
- Conditions
- Foramen Ovale, Patent, Nickel Sensitivity, Dermatitis Contact Irritant, Metal Allergy
- Trial name
- INSPIRE (NCT04713683)
- Testing
- Percutaneous Patent Foramen Ovale Closure
- Where
- Greece
- Volunteers
- 96 people
- Sponsor
- National and Kapodistrian University of Athens
Surgical Site Infection
Surgical Site Infection Rates in Obese Patients After Cesarean Delivery
The aim of this study is to determine the surgical site infection rate and patient satisfaction for subcuticular versus interrupted mattress suture in closure of skin at Cesarean delivery in obese patients.
- Trial name
- NCT01713751
- Testing
- Interrupted suturing, Subcuticular suturing
- Volunteers
- 500 people
- Sponsor
- Ain Shams University
Pain, Postoperative, Irritation (Physical)
Comparison of Skin Incision Closure Material for the Transobturator Suburethral Sling Procedure
The purpose of this study is to compare different skin closure materials for the transobturator suburethral sling procedure. Currently the investigators are using monocryl suture material as the standard for skin closure.
- Conditions
- Pain, Postoperative, Irritation (Physical), Pelvic Pain
- Trial name
- NCT01313754
- Testing
- Vicryl Suture, Dermabond
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Loma Linda University
Wound Healing Disturbance of
HIP-STITCH (Wound Recovery After THA)
This prospective randomised trial will investigate the effect of four different suturing techniques (Monocryl, Vicryl Rapide with Indermil skin glue, Dermabond Prineo, and Stryker Zip) on the amount of aberrant wound recovery…
- Trial name
- NCT06275776
- Testing
- Ethicon Monocryl Smooth Suture, Ethicon Vicryl Rapide Braided Suture, Flexifuze Indermil Topical Skin Adhesive
- Where
- Netherlands
- Volunteers
- 236 people
- Sponsor
- Reinier Haga Orthopedisch Centrum