Clinical trials: Skin Disease, Infectious
Leishmaniasis
Safety and Drug Absorption of Orally Administered Oleylphosphocholine (OlPC) in Healthy Adults
The goal of this interventional study is to assess the safety and tolerability of OlPC and to characterize the pharmacokinetics (PK) of OlPC following single, ascending doses administered orally in healthy-fed subjects.
- Trial name
- NCT06124144
- Testing
- Oleylphosphocholine
- Where
- Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Scabies
Escalated Therapy of Scabies With INFECTOSCAB 5% (Permethrin)
The ETSKABI study is a prospective, open-label, multicenter, initially single-armed and in case of treatment failure subsequently three-armed randomized clinical trial.
- Trial name
- ETSKABI (NCT04814511)
- Testing
- InfectoScab 5 % Creme, Permethrin 10 % Creme, Driponin 3 mg Tabletten
- Where
- 8 sites in Germany
- Volunteers
- 183 people
- Sponsor
- Infectopharm Arzneimittel GmbH
Chronic Cavitary Pulmonary Aspergillosis
Efficacy Of Itraconazole In Chronic Cavitary Pulmonary Aspergillosis
The purpose of this study is to determine whether there itraconazole is effective in the treatment of chronic cavitary pulmonary aspergillosis
- Trial name
- ITRACONASP (NCT01259336)
- Testing
- Itraconazole, treatment in cavitary pulmonary aspergillosis
- Where
- India
- Volunteers
- 31 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Cellulitis
Use of Corticosteroids in Children With Cellulitis
The aim of this study is to evaluate the efficacy of addition of corticosteroid therapy to antibiotic treatment during the first 48 hours of admission to the hospital in patients with cellulitis and its impact in the duration of…
- Trial name
- NCT02087527
- Testing
- Dexamethasone, Normal Saline
- Where
- Argentina
- Volunteers
- 19 people
- Sponsor
- Hospital General de Niños Pedro de Elizalde
Tinea
Efficacy Study to Evaluate the Effect of Nitric Oxide on the Treatment of Tinea Pedis (Athlete's Foot)
The purpose of this study is to determine the fungicidal efficacy of nitric oxide and it's effect on the clinical signs and symptoms associated with Tinea Pedis
- Trial name
- NCT00771342
- Testing
- Nitric Oxide, Nitrogen
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Nitric BioTherapeutics, Inc
Onychomycosis
Clinical Trial on Onychomycosis With P-3058 Nail Solution in Pediatric Population
Pediatric patients affected by mild-to-moderate distal subungual onychomycosis (DSO) or affected by white superficial onychomycosis (WSO), due to dermatophytes, will be treated topically with P-3058 nail solution according to the…
- Trial name
- NCT02547701
- Testing
- P-3058
- Where
- 5 sites in Belgium, Germany and 3 more
- Volunteers
- 20 people
- Sponsor
- Polichem S.A.
Lymphedema, Cellulitis
Evaluation of Antibacterial Soap for Treatment of Lymphedema in a Filariasis-Endemic Area
Introduction. Lymphatic filariasis is a devastating mosquito-transmitted parasitic disease that causes lymphedema or elephantiasis of the leg in 15 million persons, the majority of whom are women.
- Trial name
- NCT00139100
- Testing
- antimicrobial agent in soap
- Where
- Haiti
- Volunteers
- 200 people
- Sponsor
- Centers for Disease Control and Prevention
Cutaneous Leishmaniasis
High Dose Fluconazole in Cutaneous Leishmaniasis in Bahia and Manaus
The purpose of this study is to evaluate the therapeutic response to fluconazole in patients with cutaneous leishmaniasis caused by and L.(V.)guyanensis and L.(V.) braziliensis.
- Trial name
- NCT01953744
- Testing
- Fluconazole, Meglumine Antimoniate
- Where
- Brazil
- Volunteers
- 53 people
- Sponsor
- Hospital Universitário Professor Edgard Santos
Diabetic Foot Ulcer
Safety and Efficacy of an Antibiotic Sponge in Diabetic Patients With a Mild Infection of a Foot Ulcer
The purpose of this study is to determine whether the gentamicin-collagen sponge when combined with standard of daily wound care is safe and effective in treating mildly infected skin ulcers compared to treatment with an oral…
- Trial name
- NCT00593567
- Testing
- gentamicin-collagen sponge, Levofloxacin
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Innocoll
Herpes Labialis, Herpes Simplex Virus
A Randomized Double-Blind Control-Comparison Crossover Trial of Oral Glutamine to Suppress Frequently Recurrent Herpes Labialis
Background: A cold sore is usually a blistering rash on or near the lips, caused by infection with herpes simplex virus. After the first infection, the virus goes into a dormant (inactive) state, but it can continue to cause cold…
- Trial name
- NCT00913692
- Testing
- Glutamine, Glycine
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Genital Warts
Study of Imiquimod Cream Prior to Ablative Therapy in External Ano-Genital Warts
The purpose of this study is to compare the recurrence rate following total clearance of external genital warts (EGWs) when clearance has been obtained by imiquimod (3 applications per week for 4 weeks) followed by ablative…
- Trial name
- NCT00189293
- Testing
- Imiquimod, vehicle cream
- Where
- 12 sites in Italy
- Volunteers
- 128 people
- Sponsor
- MEDA Pharma GmbH & Co. KG
Recurrent Pityriasis Versicolor
Vitamin D Level in Recurrent PV
Serum Samples will be taken from patients with recurrent Pityriasis Versicolor for the evaluation of vitamin D level.
- Trial name
- NCT05067699
- Testing
- Human 25-Hydroxyvitamin D3 (HVD3) ELISA Kit (96 well)
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Kasr El Aini Hospital
Sporotrichosis, Chromomycosis
A Study on Rare Dermatological Infections Conducted at Three Major Reference Hospitals in Costa Rica.
In Costa Rica there are some descriptive studies of some of these rare infectious diseases (sporotrichosis, chromomycosis and mycetomas); however, there are no recent published reports.
- Conditions
- Sporotrichosis, Chromomycosis, Actinomycosis, Nocardiosis
- Trial name
- NCT06523998
- Where
- 3 sites in Costa Rica
- Volunteers
- 95 people
- Sponsor
- Caja Costarricense de Seguro Social
Herpes Simplex, Herpes Zoster
Activation of Alternative Cellular Energy (ACE) Pathway in the Therapy of Herpes Virus Infections
The research question to be addressed is whether indirect phototherapy based activation of the body's alternative cellular energy (ACE) pathway will lead to expedited healing of active herpes simplex virus (HSV) and herpes zoster…
- Trial name
- NCT00642785
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Institute of Progressive Medicine
Herpes Simplex
Phase III Randomized Study of Oral Acyclovir in Infants With Herpes Simplex Virus Infection Involving the Central Nervous System
OBJECTIVES: I. Determine the efficacy of long term suppressive therapy with oral acyclovir in infants with herpes simplex virus infection involving the central nervous system. II.
- Trial name
- NCT00006132
- Testing
- acyclovir
- Where
- 28 sites in United States, Canada
- Volunteers
- 132 people
- Sponsor
- National Center for Research Resources (NCRR)
Hidradenitis Suppurativa
Pathophysiological Basis of Hidradenitis Suppurativa
HS is a chronic inflammatory disease manifested by recurrent inflammatory nodules, abscesses and tunnels under the skin. This disease is characterized by an inflammatory process that takes place in hair follicles, sebaceous…
- Trial name
- NCT06370052
- Testing
- excision
- Volunteers
- 50 people
- Sponsor
- Clinical Hospital Center Rijeka
Herpes Simplex, HIV Infections
A Phase I/II Study of the Safety and Efficacy of Topical 1-(S)-(3-Hydroxy-2-Phosphonylmethoxypropyl)Cytosine Dihydrate (Cidofovir; HPMPC) in the Treatment of Refractory Mucocutaneous Herpes Simplex Disease in Patients With AIDS
To evaluate the safety and tolerance of topical cidofovir (HPMPC) therapy for refractory mucocutaneous herpes simplex virus disease in AIDS patients.
- Trial name
- NCT00002116
- Testing
- Cidofovir
- Where
- 9 sites in United States, Canada
- Volunteers
- 30 people
- Sponsor
- Gilead Sciences
Skin Diseases, Infectious
China Registration Study in Patients With Skin Infections
The objectives of this study is to evaluate the Safety and Efficacy of Intravenous Daptomycin (Cubicin®)Compared with that of Comparator (Vancomycin or Vancomycin Followed by Semi-synthetic Penicillin-cloxacillin) in the…
- Trial name
- NCT00772447
- Testing
- Daptomycin, Vancomycin
- Where
- 13 sites in China
- Volunteers
- 265 people
- Sponsor
- AstraZeneca
Systemic Lupus Erythematosus
Randomized Study of Oral Contraceptives or Hormone Replacement Therapy in Women With Systemic Lupus Erythematosus
OBJECTIVES: I. Determine the effect of oral contraceptives containing low-dose synthetic estrogens and progestins on disease activity in premenopausal women with inactive, stable, or moderate systemic lupus erythematosus (SLE).
- Trial name
- NCT00006133
- Testing
- estradiol, ethinyl estradiol, medroxyprogesterone
- Where
- 17 sites in United States
- Volunteers
- 970 people
- Sponsor
- National Center for Research Resources (NCRR)
Latent Tuberculosis Infection, Tuberculosis
Prospective Comparison of the Tuberculin Skin Test and Interferon-Gamma Release Assays in Diagnosing Infection With Mycobacterium Tuberculosis and in Predicting Progression to Tuberculosis
This is a prospective cohort study of persons tested for latent tuberculosis infection at either high risk for exposure to Mycobacterium tuberculosis or high risk for progression to tuberculosis disease.
- Trial name
- NCT01622140
- Where
- 10 sites in United States
- Volunteers
- 21,334 people
- Sponsor
- Centers for Disease Control and Prevention
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.