Clinical trials: Skin Diseases, Bacterial
Bronchogenic Carcinoma, Chronic Granulomatous Disease
Diagnostic Effectiveness of Virtual Bronchoscopy
This study will evaluate a new technique for examining the air passages of the lungs called "virtual bronchoscopy." It involves using computed tomography (CT) images of the chest to generate a 3-dimensional model of the walls of…
- Conditions
- Bronchogenic Carcinoma, Chronic Granulomatous Disease, Job's Syndrome, Mycobacterium Infection
- Trial name
- NCT00001515
- Testing
- virtual bronchoscopy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Blastomycosis
Amphotericin-B and Voriconazole for Pulmonary Blastomycosis
All patients with pulmonary blastomycosis requiring mechanical ventilation will have their blood concentrations measured for the antifungal drugs, amphotericin-B and voriconazole; as well as an analysis of the susceptibility of…
- Trial name
- BLASTO (NCT02283905)
- Testing
- amphotericin-B, voriconazole
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of Manitoba
Onychomycosis
A Trial to Evaluate the Safety and Efficacy of DBI-001 Gel, DBI-002 Gel, and Aqueous Gel in Subjects With Onychomycosis
This is a randomized, observer-blinded, Aqueous Gel-controlled trial examining the safety and efficacy of daily application of DBI-001 Gel vs. DBI-002 Gel vs. Aqueous Gel for 24 consecutive weeks in subjects with onychomycosis.
- Trial name
- NCT05491603
- Testing
- DBI-001, DBI-002, Aqueous Gel
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- DermBiont, Inc.
Skin Lesions, Melanocytic Nevi
Evaluating an Artificial Intelligence Tool to Help Primary Care Doctors Diagnose Skin Conditions.
This study aims to determine if an artificial intelligence (AI) medical device can help primary care doctors more accurately identify and manage various skin conditions.
- Conditions
- Skin Lesions, Melanocytic Nevi, Melanoma (Skin Cancer), Basal Cell Carcinoma of Skin
- Trial name
- LegitHealth PH (NCT07428941)
- Testing
- AI-based medical device for aided diagnosis in dermatological conditions
- Where
- Spain
- Volunteers
- 9 people
- Sponsor
- AI Labs Group S.L
Onychomycosis of Toenail
Comparison of Efficacy and Safety Between Methylene Blue-mediated Photodynamic Therapy and 5% Amorolfine Nail Lacquer for Toenail Onychomycosis Treatment
Study centre and address King Chulalongkorn Memorial Hospital Primary objective To compare the efficacy and the safety of methylene blue-mediated photodynamic therapy and 5% amorolfine nail lacquer for toenail onychomycosis in…
- Trial name
- NCT03098342
- Testing
- Methylene blue-mediated photodynamic therapy, Amorolfine 5% Nail Lacquer
- Where
- Thailand
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Hidradenitis Suppurativa (HS)
Exploration of Brain Functional Networks in Patients With Hidradenitis Suppurativa Using fMRI
The goal of this observational study is to learn whether adults with hidradenitis suppurativa (HS) have changes in resting brain activity and how these changes are related to disease severity, pain, sleep, mood, and quality of…
- Trial name
- NCT07755670
- Testing
- Routine Biologic Therapy for Hidradenitis Suppurativa
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Second Xiangya Hospital of Central South University
Onychomycosis
Topical Gel Anti-Fungal Agent for Tinea Unguium
The purpose of this study is to compare, in a controlled fashion, the response to two anti-fungal agents, naftifine or terbinafine, with vehicle in novel topical gel formulations in the treatment of subjects with distal subungual…
- Trial name
- NCT00253305
- Testing
- Organogel of naftifine, 2%, Organogel of terbinafine, 2%, Organogel of naftifine, 6%
- Where
- 5 sites in United States
- Volunteers
- 75 people
- Sponsor
- MediQuest Therapeutics
Diabetic Foot, Staphylococcus Aureus
Evaluation of the Antibiofilmogramme® Test During Diabetic Foot Infections
This is an observational study that does not change routine care. The primary objective of this study is to investigate the role of antibiogramme-antibiofilmogramme concordance (in terms of S.
- Trial name
- BioFilm PieDia (NCT02378493)
- Testing
- Antibiofilmogramme
- Where
- 6 sites in France
- Volunteers
- 33 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Hidradenitis Suppurativa, Atopic Dermatitis
A Study to Assess Molecular Changes in Adult Participants With Moderate to Severe Hidradenitis Suppurativa or With Moderate to Severe Atopic Dermatitis Receiving Subcutaneous Injections of Lutikizumab
Hidradenitis suppurativa (HS) and atopic dermatitis (AD) are chronic inflammatory skin diseases that lead to the development of skin lesions and symptoms such as pain and discomfort.
- Trial name
- NCT06524635
- Testing
- Lutikizumab
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- AbbVie
Bone and Joint Infections
Clinical Evaluation of Daptomycin Bone Penetration
Bone and joint infections are commonly due to Gram-positive bacteria. Treatment of these infections is difficult because of the need of prolonged duration of antimicrobial agents in combination with surgical procedure.
- Trial name
- DAPTO-HUS (NCT01306825)
- Where
- 3 sites in France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Strasbourg, France
Acute Radiation Dermatitis
Bacterial Cellulose-monolaurin Hydrogel for Acute Radiation Dermatitis
Acute radiation dermatitis (ARD) is almost universally experienced by patients with cancer during or after radiation therapy. This condition potentially leads to detrimental clinical outcomes as it adversely affects adherence to…
- Trial name
- NCT05079763
- Testing
- Bacterial cellulose-monolaurin hydrogel
- Where
- Philippines
- Volunteers
- 54 people
- Sponsor
- University of the Philippines
Diabetic Foot Ulcer, Pseudomonas Aeruginosa Infection
Bacteriophage Therapy TP-102 in Diabetic Foot Ulcers
This is a Phase I/IIa trial designed to evaluate topical bacteriophage therapy in patients with diabetic foot ulcers.
- Conditions
- Diabetic Foot Ulcer, Pseudomonas Aeruginosa Infection, Staphylococcus Aureus Infection, Acinetobacter Infection
- Trial name
- REVERSE (NCT04803708)
- Testing
- TP-102
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- Technophage, SA
Chronic Urticaria, Idiopathic, Hidradenitis
Evaluate Safety and Pharmacokinetics of INF904 in Subjects With Moderate to Severe Chronic Spontaneous Urticaria or Hidradenitis Suppurativa
The study duration for an individual subject includes screening (14 days), the treatment period (28 days) and the observational follow-up period of 28 days, in total 70 days ± 6 days.
- Conditions
- Chronic Urticaria, Idiopathic, Hidradenitis, Hidradenitis Suppurativa
- Trial name
- NCT06555328
- Testing
- CSU lower dose treatment, CSU high dose treatment, CSU non responders IgE - high dose treatment
- Where
- 29 sites in United States, Bulgaria and 4 more
- Volunteers
- 73 people
- Sponsor
- InflaRx GmbH
Tinea Pedis
A Study Comparing the Efficacy of TA103 and the Placebo Control in the Treatment of Interdigital Tinea Pedis.
To evaluate and compare the safety and efficacy of TA103 in the treatment of tinea pedis.
- Trial name
- NCT04883593
- Testing
- TA103
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Rheumatic Heart Disease, Rheumatic Fever
The Genetic Basis of Acquired Heart Disease in Africa
Background: An acquired heart disease is one that a person gets after they are born. Two of these are rheumatic heart disease (RHD) and endomyocardial fibrosis (EMF).
- Conditions
- Rheumatic Heart Disease, Rheumatic Fever, Endomyocardial Fibrosis, Acquired Heart Disease
- Trial name
- NCT02124109
- Where
- 2 sites in Nigeria, Uganda
- Volunteers
- 736 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Hidradenitis Suppurativa
A Small Clinical Study: Photodynamic Therapy to Treat Hidradenitis Suppurativa
This study will investigate the efficacy of Photodynamic Therapy (PDT), which is the therapeutic use of photochemical reactions, in treating hidradenitis suppurativa (HS), a chronic inflammatory condition affecting areas of skin…
- Trial name
- NCT00395187
- Testing
- Photodynamic Therapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Kansas
Moderate to Severe Plaque Psoriasis, Psoriatic Arthritis
A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)
Primary purpose of the study is to assess the concentration of bimekizumab in mature human breast milk.
- Conditions
- Moderate to Severe Plaque Psoriasis, Psoriatic Arthritis, Axial Spondyloarthritis, Hidradenitis Suppurativa
- Trial name
- BE CARING (NCT06888193)
- Testing
- Bimekizumab
- Where
- 14 sites in United States, Canada and 3 more
- Volunteers
- 20 people
- Sponsor
- UCB Biopharma SRL
Pityriasis Versicolor
The Comparative Assessment of Mycological Efficacy, Safety, Recurrence, and Cost-effectiveness of Selenium Sulfide 1.8% Shampoo Versus Ketoconazole 2% Shampoo in Pityriasis Versicolor: a Double-blind Randomized Controlled Trial
There are several topical treatment for Pityriasis Versicolor including ketoconazole and selenium sulfide. Ketoconazole is a broad spectrum anti-fungal drug from imidazole group that has been reported to be effective in PV.
- Trial name
- NCT04007237
- Where
- Indonesia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Spondyloarthritis, Ankylosing Spondylitis
Effect of a Low Starch Diet in Patients With Ankylosing Spondylitis
The aim of this study is to explore the effect of a low starch diet (reduction of at least 40%) in the gut bacteria modulation, especially Klebsiella pneumoniae, and its relation to disease activity, functional impairment and…
- Trial name
- NCT04386538
- Testing
- Low Starch Diet (LSD), General healthy eating
- Where
- Portugal
- Volunteers
- 150 people
- Sponsor
- Universidade do Porto
Tinea Pedis
Evaluate Safety and Efficacy of Naftifine Hydrochloride Gel 2% and Naftin® Gel 2% in Tinea Pedis
To compare the efficacy and safety of the test formulation Naftifine Hydrochloride Gel 2% to Naftin® (Naftifine Hydrochloride) Gel 2%
- Trial name
- NCT02335255
- Testing
- Naftifine Hydrochloride Gel 2%, Naftin® Gel 2%
- Volunteers
- 1,519 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.