Clinical trials: Skin Diseases, Bacterial
Bacterial Infections, Gram-Positive Bacterial Infections
What is the Prevalence of Methicillin-Resistant Staphylococcus Aureus in Skin and Soft Tissue Infections Presenting to the Emergency Departments of a Canadian Academic Health Care Center?
Staphylococcus aureus is the most common bacteria responsible for skin, bone, and muscle infections. Recent studies from the United States have suggested that a type of this bacterium called methicillin resistant S.
- Conditions
- Bacterial Infections, Gram-Positive Bacterial Infections, Staphylococcal Infections
- Trial name
- CA-MRSA (NCT00736554)
- Where
- Canada
- Volunteers
- 152 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Pneumonia, Bloodstream Infection
Clinical Outcomes in Patients With Infection by Resistant Microorganism
The goal of this individual patient data meta-analysis is to estimate the attributed and the associated health burden related to bloodstream infections, pneumonia, skin and soft tissue infections, surgical site infections and…
- Conditions
- Pneumonia, Bloodstream Infection, Urinary Tract Infections, Skin Infection
- Trial name
- NCT05880069
- Testing
- Pathogen resistant phenotype
- Where
- Spain
- Volunteers
- 5,000 people
- Sponsor
- Hospital Universitario Virgen Macarena
Hidradenitis Suppurativa (HS)
MAIT Cells in Hidradenitis Suppurativa
Hidradenitis Suppurativa (HS) is a chronic, debilitating inflammatory skin disease characterized by painful, purulent lesions primarily in skin folds. Its pathogenesis remains poorly understood.
- Trial name
- HS-MAIT (NCT07388446)
- Testing
- Collect lesional biopsies, Collect score from Bristol stool scale
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Hospices Civils de Lyon
Staphylococcus Aureus, Staphylococcal Skin Infections
Rapid Test to Detect Staphylococcus Aureus in Blood and Wound Infections
The purpose of this study is to determine whether the Cepheid GeneXpert system accurately detects Methicillin-Resistant and -Susceptible Staphylococcus aureus in blood cultures and wound swabs.
- Conditions
- Staphylococcus Aureus, Staphylococcal Skin Infections, Bacteremia
- Trial name
- NCT01198262
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Michael E. DeBakey VA Medical Center
Tinea Capitis
A Study Of Diflucan In Children With Ringworm Of The Scalp
The purpose of this study is to evaluate the safety and efficacy of fluconazole for the treatment of tinea capitis in pediatric patients aged 3 to 12 years.
- Trial name
- NCT00645242
- Testing
- fluconazole
- Where
- 31 sites in United States, Puerto Rico
- Volunteers
- 185 people
- Sponsor
- Pfizer
Onychomycosis
Study to Evaluate the Efficacy and Safety of P-3058 10% Nail Solution in the Treatment of Toenail Onychomycosis
The purpose of this study is to determine whether P-3058 nail solution is a safe and effective treatment for onychomycosis.
- Trial name
- NCT02549001
- Testing
- P-3058 10%, vehicle of P-3058 10%, amorolfine 5%
- Where
- 13 sites in Belgium, Bulgaria and 11 more
- Volunteers
- 953 people
- Sponsor
- Polichem S.A.
Tinea Corporis
An Open Label Pharmacokinetic Study of Naftin for Tinea Corporis
This is an open label, multi-center, multi-application pharmacokinetic study in pediatric subjects with tinea corporis.
- Trial name
- NCT02466867
- Testing
- Naftin® Cream, 2% (younger pediatric cohort), Naftin® Cream, 2% (older pediatric cohort)
- Where
- 3 sites in United States, Dominican Republic and 1 more
- Volunteers
- 27 people
- Sponsor
- Merz North America, Inc.
Hidradenitis Suppurativa
A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa
Hidradenitis suppurativa (HS) is a chronic and often painful inflammatory skin disease which includes the forming of lumps, abscesses and scars in areas of the skin such as under the breasts, under armpits, inner thighs, groin…
- Trial name
- Intrepid (NCT06468228)
- Testing
- Lutikizumab
- Where
- 279 sites in United States, Argentina and 42 more
- Volunteers
- 1,400 people
- Sponsor
- AbbVie
Osteoarthritis, Hip, Rheumatic Arthritis
AESCULAP® Plasmafit® Cementless Acetabular System With Vitelene® Vitamin E Stabilized Highly Crosslinked Polyethylene
Objectives of this study is evaluate effectivness of AESCULAP® Plasmafit® Plasmafit Cementless Acetabular System With Vitelene® Vitamin E Stabilized Highly Crosslinked Polyethylene compare to the sane sistem without Vitamin E…
- Conditions
- Osteoarthritis, Hip, Rheumatic Arthritis, Degenerative Osteoarthritis
- Trial name
- NCT05291130
- Testing
- Plasmafit® Vitelene® Vitamin E
- Where
- Russia
- Volunteers
- 400 people
- Sponsor
- Federal State Budgetary Organization, Federal Center for Traumatology, Orthopedics and Arthroplasty
Inflammatory Rheumatism, Polymyalgia Rheumatica
PRediction Of DIverse Glucocorticoids toxIcity OUtcomeS
To date, there is no available tool that allows, at individual level, determination of the probability to develop clinically relevant complications of prolonged glucocorticoid therapy.
- Conditions
- Inflammatory Rheumatism, Polymyalgia Rheumatica, Giant Cell Arteritis, Idiopathic Inflammatory Myopathies
- Trial name
- PRODIGIOUS (NCT04664465)
- Where
- 12 sites in France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Brest
Hidradenitis Suppurativa
Study to Evaluate of the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa
The purpose of this study is to evaluate the efficacy and safety of Ruxolitinib cream in participants with Hidradenitis Suppurativa.
- Trial name
- NCT05635838
- Testing
- Ruxolitinib cream, Vehicle cream
- Where
- 20 sites in United States, Canada
- Volunteers
- 69 people
- Sponsor
- Incyte Corporation
Adenovirus, Anesthesia
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Understudied drugs will be administered to children per standard of care as prescribed by their treating caregiver and only biological sample collection during the time of drug administration will be involved.
- Conditions
- Adenovirus, Anesthesia, Anxiety, Anxiolysis
- Trial name
- PTN_POPS (NCT01431326)
- Testing
- The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada and 3 more
- Volunteers
- 3,520 people
- Sponsor
- Daniel Benjamin
Tinea Capitis
Safety and Efficacy of NAFT900 in Children With Tinea Capitis
A Double-Blind, Randomized, Vehicle-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of NAFT-900 in Children Aged 6 to < 13 Years with Tinea Capitis
- Trial name
- NCT02658292
- Testing
- Naftifine hydrochloride foam, 3%, Vehicle
- Sponsor
- Merz North America, Inc.
Chronic Renal Failure
Detection of Latent Tuberculosis in Hemodialysis Patients
This study aims to compare the performance of the tuberculin skin test, used for more than 50 years as a diagnostic tool for latent tuberculosis infection, with 2 blood tests which have recently become commercially available…
- Trial name
- NCT00695734
- Where
- Switzerland
- Volunteers
- 62 people
- Sponsor
- University Hospital, Geneva
Dermatophyte Infection, Terbinafine Adverse Reaction
Comparison of Efficacy of Double Dose Oral Terbinafine Vs Itraconazole in Treatment of Dermatophyte Infections of Skin.
Study would be conducted to compare the efficacy and safety of double than usual dose oral terbinafine versus itraconazole in treatment of dermatophyte infections of skin in patient presenting at dermatology department of Pak…
- Conditions
- Dermatophyte Infection, Terbinafine Adverse Reaction, Itraconazole Adverse Reaction
- Trial name
- NCT04880980
- Testing
- Terbinafine Pill, Itraconazole capsule
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Pak Emirates Military Hospital
Hidradenitis Suppurativa
Evaluate the Efficacy of TIRZEPATIDE for the Treatment of Moderate to Severe HS Hidradenitis Suppurativa
The purpose of this study is to determine the clinical efficacy and safety of tirzepatide in subjects with moderate to severe hidradenitis suppurativa.
- Trial name
- NCT06301256
- Testing
- TIRZEPATIDE
- Volunteers
- 20 people
- Sponsor
- Florida Academic Centers Research and Education, LLC
Hidradenitis Suppurativa
Hidradenitis Suppurativa Study of Izokibep
Izokibep is a small protein molecule that acts as a selective, potent inhibitor of interleukin 17A, to which it binds with high affinity.
- Trial name
- NCT05905783
- Testing
- Izokibep
- Where
- 98 sites in United States, Canada and 6 more
- Volunteers
- 258 people
- Sponsor
- ACELYRIN Inc.
Hidradenitis Suppurativa
Aviclear for Hidradenitis Suppurativa (HS)
The objective is to evaluate the safety and efficacy of the Cutera 1726 nm laser system (also referred to as AviClear) for the treatment of HS.
- Trial name
- NCT06801795
- Testing
- AviClear
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Miami
Eumycetoma
Eumycetoma Long-term Post-Treatment Follow-Up Study
To assess the long-term recurrence rate of eumycetoma in clinical trial participants treated in the phase II DNDi-FOSR-04-MYC clinical trial.
- Trial name
- NCT06514183
- Testing
- Clinical diagnosis of recurrence
- Where
- Sudan
- Volunteers
- 51 people
- Sponsor
- Drugs for Neglected Diseases
Hidradenitis Suppurativa
A Study to Test the Efficacy, Safety and Pharmacokinetics of Bimekizumab in Subjects With Moderate to Severe Hidradenitis Suppurativa.
Hidradenitis suppurativa (HS) is a painful, long-term skin condition that causes abscesses and scarring on the skin.
- Trial name
- NCT03248531
- Testing
- Bimekizumab, Adalimumab
- Where
- 31 sites in United States, Australia and 6 more
- Volunteers
- 90 people
- Sponsor
- UCB Biopharma SRL