Clinical trials: Skin Flaps
Breast Cancer Surgery, Reconstruction Breast Surgery
Improvement in Breast Skin Sensibility After Breast Reconstruction: a Comparison of 3 Surgical Techniques
The goal of this clinical trial is to learn if nerve sutures in free flap breast reconstruction can optimize sensibility in the reconstructed breast in patients opting for DIEP flap breast reconstruction due to breast cancer or…
- Conditions
- Breast Cancer Surgery, Reconstruction Breast Surgery, Sensitization, DIEP Flap Breast Reconstruction
- Trial name
- S-DIEP (NCT06930378)
- Testing
- Nerve Suture
- Where
- Switzerland
- Volunteers
- 63 people
- Sponsor
- Patricia Esther Engels
Cancer
Objective Flap Assessment During Reconstructive Surgery
The main purpose of this study is to test the ergonomics of an investigational imaging system that can take pictures of blood vessels under the skin.
- Trial name
- NCT00952107
- Testing
- FLARE imaging system
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Beth Israel Deaconess Medical Center
Breast Cancer, Oncoplastic Breast Surgery
Scarless Advanced Breast Extended Oncoplasty: The ScarABEO Study
Breast conserving surgery followed by radiotherapy is the gold standard treatment for early breast cancer. Cases with unfavorable tumor volume to breast volume ratio or challenging localizations are at higher risk of margin…
- Conditions
- Breast Cancer, Oncoplastic Breast Surgery, Oncoplastic Breast-conserving Surgery, Chest Wall Perforator Flap
- Trial name
- ScarABEO (NCT06906237)
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Istituto Oncologico Veneto IRCCS
Decubitus Ulcer
Case Series Assessing TissuGlu® Surgical Adhesive in Flap Surgery for Decubitus Repair
To evaluate the impact of a high strength lysine-based adhesive (TissuGlu® Surgical Adhesive) on complications and revision rates in large flap surgery for decubitus repair.
- Trial name
- NCT03482999
- Testing
- TissuGlu Surgical Adhesive
- Volunteers
- 50 people
- Sponsor
- Cohera Medical, Inc.
Breast-cancer
Seroma Formation After Modified Radical Mastectomy With Flap Fixation Technique in Breast Cancer Patients
The goal of this clinical trial is to evaluate the effectiveness of mastectomy flap fixation in breast cancer patients. The main questions it aims to answer are: To compare seroma formation after mastectomy flap fixation with…
- Trial name
- NCT06243796
- Testing
- Flap fixation technique
- Where
- Thailand
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nakhon Phanom Hospital
Breast Cancer, Blood Loss, Surgical
Role of TXA in Patients Undergoing Breast Free Flap Reconstruction
Tranexamic acid (TXA) is a synthetic, competitive lysine receptor inhibitor on plasminogen. It ultimately stabilizes the fibrin matrix, therefore used as a hemostatic agent for various indications.
- Trial name
- NCT06428682
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Virginia
Lymphedema, Breast Neoplasm
Immediate Axillary Plasty With a Pedicled Muscle Flap for Breast Cancer Related Lymphedema Prevention
The purpose of this comparable cohort study is to evaluate the efficacy and safety of immediate axillary plasty with pedicled partial Latissimus Dorsi muscle flap for lymphedema prevention in breast cancer patients who are…
- Trial name
- NCT02318615
- Testing
- Immediate Axillary Plasty
- Volunteers
- 450 people
- Sponsor
- Peking University People's Hospital
Ischemia
Skin Flap Visible Light Spectroscopy (VLS) Oximetry for Monitoring Free-Flap Ischemia During Breast Reconstruction and Recovery
The purpose of the study is to understand the relevance of tissue oximetry measures of tissue flaps during surgery and during recovery, and to determine if T-Stat is a reliable and early method of detecting compromised flaps.
- Trial name
- NCT01173133
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Spectros Corporation
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Matrix Rotation Flap Versus Single Incision Lateral Sulcus Mammoplasty
The study seeks to compare the single-incision lateral mammoplasty technique with the matrix rotation flap in patients with breast carcinoma.
- Trial name
- SLIM (NCT07022509)
- Testing
- proceduder surgery, Technique surgery
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Batterjee Medical College
Breast Cancer, Breast Reconstruction
Incorporating Robotic Surgery in Both Mastectomy and DIEP Flap Reconstruction
A prospective study will be conducted to assess the outcomes of patients who underwent concurrent robotic-assisted mastectomy and robotic-assisted free DIEP flap harvest for breast reconstruction between March 2020 and June 25…
- Trial name
- NCT05945914
- Testing
- Oncoplastic Entirely Robot-Assisted Approach (OPERA)
- Where
- Taiwan
- Volunteers
- 9 people
- Sponsor
- Chang Gung Memorial Hospital
Breast/Surgery
Nipple-sparing Mastectomy in Combined With Buried Flap Monitoring
1. Learning curve of ms-Tram and DIEP breast reconstructions surgery are important to guide the training of new surgeon. 2. Buried flap post operative monitoring without implantable doppler was seldom studied, a validated…
- Trial name
- NCT05560633
- Testing
- No intervention
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Perfusion; Complications
The Effect of Nitroglycerin Ointment, Fluorescent Angiography, and Incisional Negative Pressure Wound Therapy on Mastectomy Skin Flap Perfusion-Related Problems
This is a randomized study using a variety of techniques to compare and examine blood flow to the remaining skin after mastectomy. All treatments being used are considered standard of care and are not experimental.
- Trial name
- NCT03716050
- Testing
- Nitroglycerin, Negative Pressure Wound Therapy/ Wound VAC, Fluorescent Angiography with indocyanine-green (not to exceed 5mg/kg)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Wake Forest University Health Sciences
Pressure Ulcer
A Randomized, Prospective Clinical Trial of Immediate Flap Closure Versus Wound Care for Management of Late-stage Pressure Ulcers
The purpose of this study is to compare the number of and degree of pressure ulcers healed, as measured by intact skin at the original ulcer site at 6 months of follow-up in patients randomized to immediate operative closure…
- Trial name
- NCT02272881
- Testing
- surgical reconstruction, wound management
- Sponsor
- Santa Barbara Cottage Hospital
Breast Reconstruction, Breast Cancer
Optimizing Postoperative Recovery After Breast Reconstruction With Autologous Tissue (BestDIEP)
Women who have their breast reconstructed with autologous tissue seem to be more satisfied with their breast. However, autologous breast reconstruction entails a bigger operation, and the usage of more health care resources, than…
- Trial name
- BestDIEP (NCT05363189)
- Testing
- Venous augmentation, Traditional ERAS (enhanced recovery after surgery) protocol, Sahlgrenska recovery protocol
- Where
- Sweden
- Volunteers
- 380 people
- Sponsor
- Vastra Gotaland Region
Breast Neoplasms
Women Underwent TRAM Surgery: Its Influence on Abdominal Muscle Function and the Effects of Therapeutic Exercises
The unilateral transverse rectus abdominis musculocutaneous (TRAM) flap is a major operation widely used for breast reconstruction.
- Trial name
- NCT04886921
- Testing
- Abdominal muscle training
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Pressure Ulcer
Comparing Different Surgical Techniques for Coverage of Pressure Ulcer
The Plastic, Reconstructive and Aesthetic Surgery department of Montpellier was born out of the Wound and Healing department, the first unit of this type to be created in Europe.
- Trial name
- NCT04446936
- Testing
- Flap covering for pressure ulcer
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Carcinoma
PARTial BREast RECONstruction With Chest Wall Perforator Flap
The goal of this observational study is to ascertain the outcomes following partial breast reconstruction using chest wall perforator flaps after breast conservation surgery.
- Conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Carcinoma, Breast Neoplasms, Breast Surgery
- Trial name
- PartBreCon (NCT06728527)
- Where
- United Kingdom
- Volunteers
- 1,001 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Breast Tumor, Perforator Flap
Outcomes of Local Perforator Flaps in Oncoplastic Surgery
This is a single center experience of using local perforator flaps in partial breast reconstruction for breast tumors while evaluating cosmetic outcomes, patient satisfaction and well-being using a validated self-administered…
- Conditions
- Breast Tumor, Perforator Flap, Breast Cancer, Oncoplasty
- Trial name
- NCT05389605
- Testing
- No intervention was undertaken
- Where
- Pakistan
- Volunteers
- 25 people
- Sponsor
- Aga Khan University
Breast Cancer
Influence of the Superficial Inferior Epigastric System in Deep Inferior Epigastric Perforator (DIEP) Flaps
The purpose of this study is to determine in-vivo the effects the contralateral superficial inferior epigastric vascular system has on the perfusion of Zone IV of deep inferior epigastric perforator flaps.
- Trial name
- NCT01464970
- Testing
- Both Superficial Inferior Artery and Vein Clamped, Superficial Inferior Epigastric Vessels both unclamped, SIE Artery Unclamped, Vein Clamped
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- NHS Greater Glasgow and Clyde
Disorders of Skin Grafts and Flaps
Predicting Breast Flap Necrosis by Spatial Frequency Domain Imaging
The current surgical procedure for breast diseases places an emphasis on the conservation of breast skin in order to provide more optimal reconstruction.
- Trial name
- NCT02273076
- Testing
- Spatial Frequency Domain Imaging
- Where
- United States
- Sponsor
- University of California, Irvine