Clinical trials: Skin Flaps
Breast Neoplasms
Delaying the Superficial Inferior Epigastric Artery (SIEA) Flap and Determining the Change in SIEA Diameter and Blood Flow
The purpose of this study is to determine whether delaying the superficial inferior epigastric artery (SIEA) flap results in widening of diameter and enhancing of blood flow of its donor artery.
- Trial name
- NCT01247129
- Testing
- Delay procedure of SIEA flap.
- Where
- Slovenia
- Volunteers
- 26 people
- Sponsor
- University Medical Centre Ljubljana
Post-Op Complication, Skin Flap Necrosis
Quantifying the Venous Congestion Curve of a Tissue Oximetry Device
The purpose of this research study is to measure rate of decline and pattern of tissue oxygenation using the device, ViOptix T.Ox. ViOptix probes will be secured to the arm and hand.
- Trial name
- NCT05592145
- Testing
- ViOptix
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Frey Syndrome
FDFG Versus SMAS Flap After Superficial Parotidectomy; Evaluation of Functional and Esthetic Outcome
After parotidectomy, Frey's syndrome and facial disfigurement are the most common encountered complications. Free dermal fat graft (FDFG) and the superficial musculoaponeurotic system (SMAS) flap, have very promising results.
- Trial name
- NCT05452837
- Testing
- FDFG, SMAS
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Menoufia University
Stage II Cutaneous Melanoma
COmparison of the Use of a PERforator Flap Versus Total Skin GRAft in the Management of Loss of Substance After Resection of Cutaneous Melanoma - Pilot Study
Melanoma is an aggressive and potentially fatal skin cancer and was the fifth most commonly diagnosed cancer among both men and women in the United States in 2022.
- Trial name
- COPERGRAM1 (NCT07354152)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Nantes University Hospital
Prophylactic Mastectomy
Prophylactic Mastectomy: Prospective Evaluation of the Correlation Between Skin Flap Thickness, Residual Glandular Tissue and Skin Necrosis by Imaging and Clinical Examination
Breast cancer is the most common form of cancer among women. Five to ten percent of all breast cancers are due to hereditary factors, with pathogenic variants in the breast cancer genes BRCA1/2 accounting for 2-5% of all breast…
- Trial name
- NCT05162677
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- Umeå University
Skin Necrosis, Breast Reconstruction
B4P Trial - BLOOM43 for Preconditioning
The goal of this clinical trial is to evaluate the use of the Plexaa preconditioning device (BLOOM43) in patients undergoing reconstructive breast surgery for breast cancer.
- Conditions
- Skin Necrosis, Breast Reconstruction, Breast Surgery
- Trial name
- NCT07340632
- Testing
- BLOOM43
- Volunteers
- 60 people
- Sponsor
- Plexaa Ltd
Breast Cancer, Breast Reconstruction
The Use of Laser-Assisted Indocyanine Green Dye Angiography to Predict Mastectomy Skin Flap Viability
In the investigators previous study of 51 breast reconstructions (32 patients), we compared three different assessments of vascular perfusion of tissue; clinical judgment, fluorescein dye angiography (FDA) and laser-assisted…
- Conditions
- Breast Cancer, Breast Reconstruction, Mastectomy
- Trial name
- ICG (NCT01554267)
- Testing
- Laser-Assisted ICG Dye Angiography (SPY System)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Stony Brook University
Breast Cancer
TAP vs QL for Postoperative Analgesia After DIEP Free Flap Breast Reconstruction
The purpose of this study is to compare the efficacy of Transversus abdominus plane (TAP) block and Quadratus Lumborum (QL) block on the quality of recovery after breast reconstruction with deep inferior epigastric perforator…
- Trial name
- NCT05301595
- Testing
- TAP block, QL Block
- Where
- Canada
- Sponsor
- Ottawa Hospital Research Institute
Breast Cancer, Breast Reconstruction
NIR Device for Assessment of Skin Flap Perfusion in Breast Surgery: A Pilot Interventional Study
The goal of this single-center, nonrandomized, interventional non-profit pilot study is to evaluate the feasibility and clinical utility of a non-invasive near-infrared spectroscopy (NIRS) imaging device for assessing skin-flap…
- Conditions
- Breast Cancer, Breast Reconstruction, Mastectomy
- Trial name
- ADisIRast (NCT07680296)
- Testing
- Snapshot NIR V3.0
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- National Research Council, Institute of Clinical Physiology, Italy
Breast Reconstruction, Breast Cancer
Successful Microsurgical Breast Reconstruction in Minimally Invasive Mastectomy
A retrospective chart review will be conducted to identify patients who received breast reconstruction surgery with DIEP flaps by a single plastic surgeon in one medical center between November 2018 and July 2022.
- Trial name
- NCT05943873
- Where
- Taiwan
- Volunteers
- 63 people
- Sponsor
- Chang Gung Memorial Hospital
Head and Neck Cancer
Free Skin Grafting to Reconstruct Donor Sites After Radial Forearm Flap Harvesting
Reconstruction of the donor site after radial forearm flap harvesting is a common procedure in maxillofacial plastic surgery. Unfortunately, free skin graft transplantation faces wound healing impairments such as necrosis…
- Trial name
- NCT05137639
- Testing
- Platelet-rich fibrin (PRF)
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Breast Cancer, Mastectomy; Lymphedema
OPERA - Incorporating Robotic Surgery in Both Mastectomy and DIEP Flap Reconstruction
Current breast cancer surgery is achieving minimally invasive approach to reduce incision while providing better surgical vision and freedom in mastectomy.
- Trial name
- NCT06415526
- Testing
- OPERA
- Where
- Taiwan
- Volunteers
- 14 people
- Sponsor
- Chang Gung Memorial Hospital
Diabetic Foot Ulcer, Venous Leg Ulcer
PLASOMA Ultimate Safety & Efficacy Study
The purpose of the PULSE study are the followingL A.To perform post market clinical follow up (PMCF) on safety and efficacy: 1. Safety: To confirm transient short-terms side effects and verify long-term/outstanding risks. 2.
- Conditions
- Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer, Burn Wound
- Trial name
- PULSE (NCT04828304)
- Testing
- PLASOMA
- Where
- 6 sites in Netherlands
- Volunteers
- 101 people
- Sponsor
- Plasmacure
Ductal Breast Carcinoma in Situ, Lobular Breast Carcinoma in Situ
Stereotactic Image-Guided Navigation During Breast Reconstruction in Patients With Breast Cancer
Many hospitals, including the Ohio State University Medical Center, will take pictures of the blood vessels in a patient's abdomen before they decide to perform a breast reconstruction using the patient's own tissue.
- Conditions
- Ductal Breast Carcinoma in Situ, Lobular Breast Carcinoma in Situ, Recurrent Breast Cancer, Stage IA Breast Cancer
- Trial name
- NCT01729832
- Testing
- breast reconstruction, intraoperative imaging
- Sponsor
- Ohio State University Comprehensive Cancer Center
Breast Cancer
Nerve Coaptation in DIEP Flap Breast Reconstruction
The sensory recovery of the breast remains an undervalued aspect of breast reconstruction and surgical reinnervation is not regarded as a priority by most reconstructive surgeons.
- Trial name
- NCT03428789
- Testing
- Sensory nerve coaptation
- Where
- Netherlands
- Volunteers
- 81 people
- Sponsor
- Maastricht University Medical Center
Surgical Wound
Single-Use Negative Pressure Wound Therapy for Free Flap Donor Sites
Various management options for free flap donor sites that require split thickness skin grafting exist. None has proven superior from both a patient care and a cost standpoint.
- Trial name
- NCT03340025
- Testing
- PICO Single Use Negative Pressure Wound Therapy System, xeroform gauze
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Skin Flaps, Lung Cancer
Reminder Messages for Lung Cancer Screening
To test lung cancer screening reminder messages to help adults who 1) 50 to 80 years of age, 2) smoke or have smoked, and 3) do not have history of lung cancer by self-report.
- Trial name
- NCT05952778
- Where
- United States
- Volunteers
- 133 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer
Retrospective and Prospective Evaluation of Scapulohumeral Comfort, Aesthetic Result and Quality of Life
The dorsalis major flap is an interesting therapeutic option in breast reconstruction because of reliability and reproducibility.
- Trial name
- QUARLAMI (NCT05316389)
- Testing
- Breast reconstruction
- Where
- France
- Volunteers
- 190 people
- Sponsor
- Institut Cancerologie de l'Ouest
Breast Cancer
WashU DIEP Flap Video and Patient Understanding Improvement
Patients will complete a survey before and after watching the WashU DIEP Flap Video at their pre-operative standard of care visit, and a third survey at their post-operative standard of care visit.
- Trial name
- NCT06864754
- Testing
- WashU DIEP Flap Video
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Washington University School of Medicine
Breast Cancer
Sensory Nerve Coaptation in DIEP Flap Breast Reconstruction
Restoring the sensation of the breast becomes increasingly recognized as a critical part of autologous breast reconstruction. A prospective study was conducted of all patients who underwent either innervated or non-innervated…
- Trial name
- NCT04093999
- Testing
- Sensory nerve coaptation
- Where
- Netherlands
- Volunteers
- 126 people
- Sponsor
- Maastricht University Medical Center