Clinical trials: Skin Flaps
Camptodactyly
Treatment of Camptodactyly With Radial Longitudinal Flap Versus Full-Thickness Skin Graft
The goal of this randomized clinical trial is to compare two surgical techniques used for skin coverage after surgical correction of camptodactyly, a condition in which one or more fingers remain bent and cannot be fully…
- Trial name
- NCT07786701
- Testing
- Radial Longitudinal Flap, Full-Thickness Skin Graft
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- Associação de Assistência a Criança Deficiente
Best Tissue Constituent for Plantar Surface
Functional Outcome of Free Muscle Flaps Versus Free Skin Flaps for Post-traumatic Foot Plantar Surface Reconstruction
the investigators are trying to detect what is the best tissue constituent suitable for reconstruction of large post traumatic sof tissue defects of foot plantar surface
- Trial name
- NCT03152812
- Testing
- plantar surface reconstruction by free flaps
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- alhussein Ahmed Mahmoud El-Dahshan
Postoperative Bleeding, Skin Cancer Face
Tranexamic Acid in Nasal Mohs Reconstruction
This study will be a prospective randomized control trial to evaluate the effects of subcutaneously administered TXA among patients undergoing nasal Mohs reconstruction with local flaps at VUMC.
- Trial name
- NCT06057675
- Testing
- Treatment (tranexamic acid and 1% lidocaine with 1:100,000 epinephrine), Control (1% lidocaine with 1:100,000 epinephrine)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Breast Cancer, Exercise
The Effect of a Post-operative Exercise Programme Versus Standard Care on Physical Fitness of Patients With Breast Cancer Undergoing Deep Inferior Epigastric Perforator (DIEP) Flap Reconstruction Surgery
All patients undergoing mastectomy for breast cancer should be offered the option of reconstructive surgery. The Deep Inferior Epigastric Perforator Flap or DIEP reconstruction as it is commonly referred to, is becoming the…
- Trial name
- EXERCISE DIEP (NCT07672392)
- Testing
- Structured individualised 12-week post operative exercise programme
- Where
- Ireland
- Volunteers
- 78 people
- Sponsor
- Royal College of Surgeons, Ireland
Burn of Face, Head and/or Neck, Peeling
Histological Skin Changes of Different Peeling Agents in Surgically Subcutaneous Undermined Skin
The purpose of this study is to examine the histological skin changes induced by different peeling agents (Trichloroacetic acid 25% and 40% and phenol/croton oil) in subcutaneous undermined facial skin flaps.
- Trial name
- NCT02848209
- Testing
- TCA 20% Peeling, Phenol/croton oil Peeling, TCA 40% Peeling
- Where
- Spain
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Wounds and Injuries, Wound Infection
Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries
- Trial name
- FTFDT2 (NCT03880188)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Breast Cancer, Acquired Absence of Breast
Long-term Evaluation of Quality of Life and Aesthetic Outcomes After Autologous Breast Reconstruction Using the Profunda Artery Perforator (PAP) Flap
Breast reconstruction using autologous tissue is an important option for women undergoing mastectomy for breast cancer. The profunda artery perforator (PAP) flap is a reliable alternative when abdominal tissue is unavailable or…
- Conditions
- Breast Cancer, Acquired Absence of Breast, Autologous Breast Reconstruction
- Trial name
- QUALIPAP (NCT07728565)
- Where
- France
- Volunteers
- 264 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breast Carcinoma
Skin Sparing Mastectomy and Immediate Breast Reconstruction With Latissimus Dorsi Flap After Neoadjuvant Chemotherapy and Radiotherapy (M-RIC)
The aim of the study is to evaluate the feasibility and morbidity of skin sparing mastectomy and immediate breast reconstruction with latissimus dorsi flap after neoadjuvant chemotherapy and radiotherapy in invasive breast…
- Trial name
- M-RIC (NCT01199354)
- Testing
- Mastectomy, preservation of the skin envelope,followed by immediate reconstruction with autologous latissimus dorsi flap.
- Where
- 11 sites in France
- Volunteers
- 80 people
- Sponsor
- Clinique Clementville
Breast Cancer
BENEFIT OF MECHANICAL ISCHEMIC PRECONDITIONING ON TOLERANCE OF ADIPOSE TISSUE TO ISCHEMIA REPERFUSION OF TYPE DIEP (DEEP INFERIOR EPIGASTRIC PERFORATOR) FREE FLAPS.
Breast cancer is the most common cancer amongst women in terms of frequency, with more than 50 000 newly diagnosed cases per year in France. The average 5-year survival rate for women with breast cancer is around 85%.
- Trial name
- PRIMIDIEP (NCT05373069)
- Testing
- Mechanical ischemic preconditioning of diep-type flap
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breast Cancer, Perforator Flap
Deep Inferior Epigastric Artery Flap for Breast Reconstruction
Background: There is no consensus on the duration of prophylactic antibiotics for autologous breast reconstruction after mastectomy.
- Conditions
- Breast Cancer, Perforator Flap, Anti-Infectives Adverse Reaction, Infections
- Trial name
- NCT05088239
- Testing
- prophylactic antibiotics duration
- Volunteers
- 108 people
- Sponsor
- Chiayi Christian Hospital
Breast Reconstruction
Secondary Breast Reconstruction With a Flap of Skin From the Back
The purpose of this study is to examine the different outcomes of breast reconstruction in women who are treated for breast cancer with mastectomy and subsequently have delayed breast reconstruction by one of two different…
- Trial name
- NCT02169011
- Testing
- Latissimus Dorsi Flap Reconstruction, TAP Flap Reconstruction
- Where
- 4 sites in Denmark, Norway
- Volunteers
- 50 people
- Sponsor
- Vejle Hospital
Breast Cancer
Preoperative Imaging in DIEP Flap Breast Reconstruction
The purpose of this study is to determine whether preoperative abdominal imaging using either CT angiogram (CTA), or MR angiogram (MRA) will impact perforator dissection time, cost, and patient outcomes in DIEP flap breast…
- Trial name
- NCT02111239
- Testing
- CTA, MRA
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Breast Cancer
Impact of Radiotherapy on Patients Undergoing DIEP Flap Breast Reconstruction
The investigators intend to undertake a study to investigate the effect of radiotherapy on deep inferior epigastric perforator flap reconstructions (DIEP).
- Trial name
- NCT03072316
- Testing
- 3D surface imaging, semi-structured interview, applanation tonometry
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Breast Cancer
Autologous vs. Implant-based Breast Reconstruction
Although breast reconstruction is an integral part of breast cancer treatment, there is little high-quality evidence to indicate which method is the most effective.
- Trial name
- GoBreast II (NCT06195865)
- Testing
- DIEP-flap, Implant
- Where
- 2 sites in Sweden
- Volunteers
- 250 people
- Sponsor
- Vastra Gotaland Region
Breast Cancer
CT-Angiography Prior to DIEP Flap Breast Reconstruction
This study will Investigate whether or not preoperative computed tomography (CT) angiography will lower operative times and post operative complications for breast reconstruction performed with a deep inferior epigastric artery…
- Trial name
- NCT02883387
- Testing
- Preoperative CT angiography, No Preoperative Imaging
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Colorado, Denver
Ingrown Toenail
P : Ingrown Toenail Patient I : Bird Flap Surgery C : Noel Winograd Method O : Recurrence, Complications, Functional Outcome, Pain,
The treatment of ingrown toenails is highly diverse, with numerous surgical techniques described in the literature alongside conservative approaches.
- Trial name
- ITN (NCT06862232)
- Testing
- Modified Winograd "Bird Flap" Technique, Classic Winograd Technique, Modified Noel Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Kutahya City Hospital
Skin Cancer Excision Site, Basal Cell Carcinoma
Impact of Dysport on PMFF Donor Scar
The purpose of this research study is to investigate the effect of pre-operative injections of Dysport (Abobotulinumtoxin-A, commonly known as "Botox") on the cosmetic appearance of and overall satisfaction with study…
- Conditions
- Skin Cancer Excision Site, Basal Cell Carcinoma, Squamous Cell Carcinoma, Melanoma
- Trial name
- NCT07720726
- Testing
- Abobotulinumtoxin-A, Control- Saline injection
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Vanderbilt University Medical Center
Disability or Chronic Disease Leading to Disablement, Pressure Ulcer
Treatment of Osteomyelitis-associated Pressure Ulcers by Surgical Flaps and Anti-bacterial Agents
People with neuromotor disability (i.e. following an inborn or acquired spinal cord, cerebral or peripheral neurological lesion) are at high risk of osteomyelitis-associated pressure ulcers.
- Conditions
- Disability or Chronic Disease Leading to Disablement, Pressure Ulcer, Osteomyelitis
- Trial name
- NCT05713149
- Testing
- Surgical flap and anti-bacterial agents
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Institut de Sante Parasport Connecte Synergies
Breast Neoplasms, Mammaplasty
ARTISS a Single-centre Randomised Control Study
The Influence of ARTISS on post-operative abdominal drainage and seroma formation in DIEP/MS-TRAM free flap breast reconstruction patients.
- Trial name
- ARTISS (NCT04931615)
- Testing
- ARTISS 4mL Fibrin Sealant Topical Solution (Frozen), no ARTISS
- Where
- United Kingdom
- Volunteers
- 135 people
- Sponsor
- Mid and South Essex NHS Foundation Trust
Breast Carcinoma
Evaluating Mechanical Properties of Post-Mastectomy Skin Flaps to Estimate Reconstruction Risks, the EMPOWER Study
This study evaluates the skin and surrounding soft tissue that is removed during an implant reconstruction after a mastectomy.
- Trial name
- NCT06584396
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- M.D. Anderson Cancer Center