Clinical trials: Skin Graft
Burn Injury
Exercise in Burn Survivors: Cooling Modalities
This project will identify the efficacy of cooling modalities aimed to attenuate excessive elevations in skin and internal body temperatures during physical activity in well-healed burn survivors.
- Trial name
- NCT04512976
- Testing
- Control (no cooling modalities), Water Spray Only, Fan Only
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Burns
The Dermisgraft Epithelialization and Late Scar Healing
Study Synopsis Title; The dermis graft: epithelialization and late scar evaluation A Clinical Prospective multicenter trial Objectives; The objective of this study is to compare a dermal graft with a conventional split thickness…
- Trial name
- NCT05189743
- Testing
- Skin transplantation to heal burn injuries
- Where
- Sweden
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Burn Scar
Fat Grafting in Skin-grafted Deep Burn Scars
fat grafting in human skin-grafted immature burn scars histological, clinical and photographic follow-up
- Trial name
- NCT03627650
- Testing
- lipofilling/ fat grafting
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Skin Graft Wounds
Comparison of Dressing Materials of Donor Site of Split-thickness Skin Graft; Paraffin Mesh Gauze vs Povidone-Iodine Foam at SMBB Institute of Trauma Karachi
The goal of this clinical trial is to learn if povidone-iodine foam dressing is better in achieving complete reepithelialization of donor site wounds after harvest of split-thickness skin graft as paraffin mesh gauze.
- Trial name
- NCT07257991
- Testing
- Povidine-iodine foam dressing for donor site of Split-thickness skin graft, Paraffin mesh gauze dressing for donor site of Split-thickness skin graft
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Shaheed Mohtarma Benazir Bhutto Institue of Trauma
Peyronie's Disease
Investigation of Surgery, Collagenase, and Restorex for the Improvement of Peyronie's
The purpose of this study is to compare key clinical outcomes of collagenase clostridium histolyticum injections versus surgery for the management of Peyronie's Disease.
- Trial name
- iSCRIP (NCT04786106)
- Testing
- Collagenase Clostridium Histolyticum 0.9 MG [Xiaflex] (CCH), Penile Plication Surgery, Incision and Grafting (I&G) Surgery
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Charitable Union for the Research and Education of Peyronie's Disease
Cicatrix, Wound Healing
Investigation of the Accelerated Healing and Anti-scarring Potential of Avotermin (Juvista) in Split Skin Graft Donor Sites
The purpose of this study is to investigate the accelerated-healing potential of injection or injection plus topical application of Juvista to minor split skin grafts (SSG).
- Trial name
- NCT00984503
- Testing
- Avotermin
- Where
- United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Renovo
Wounds and Injuries
Feasibility Study for Fibroblast Autologous Skin Grafts
This research is being done to determine if investigators can change skin from one type to another. Specifically, investigators are interested in making normal skin into the thicker skin found on our palms and soles.
- Trial name
- NCT01964859
- Testing
- autologous skin fibroblasts, Filler Product
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Burns, Skin Graft Complications
Suprathel Versus Xeroform for the Management of Skin Graft Donor Sites
The investigators aim to study whether Suprathel, a synthetic temporary skin substitute developed by PolyMedics Innovations GmBH aids in the management of patient pain and wound healing when compared to the current standard…
- Conditions
- Burns, Skin Graft Complications, Skin; Deformity
- Trial name
- Suprathel (NCT04014400)
- Testing
- Suprathel or Xeroform donor site application
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Head and Neck Cancer, Surgery--Complications
Tumescence in HNC Skin Graft Reconstruction
Our primary objective is to determine if the use of tumescence has a meaningful effect on STSG uptake at the recipient site. This is an important outcome because poor graft uptake results in the need for prolonged local wound…
- Conditions
- Head and Neck Cancer, Surgery--Complications, Graft Failure
- Trial name
- NCT04967391
- Testing
- Tumescence During STSG Harvest
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Skin Graft Scar, Split-Thickness Skin Graft (STSG)
Efficacy and Safety Evaluation of EASYEF® in Acute Wound (Split-thickness Skin Graft Donor Site)
This study is a prospective study, randomized, using control, open-label, single-center to evaluate the efficacy and safety of EASYEF® in acute wound (split-thickness skin graft donor site).
- Trial name
- NCT05335720
- Testing
- rhEGF
- Where
- Indonesia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- PT. Daewoong Infion
Skin Graft
Donor Site Healing Response to Low Level Laser Therapy Following Skin Graft Surgery
PURPOSE: The purpose of the study is to evaluate the effect of (LLLT) on donor site wound healing following skin graft surgery. BACKGROUND: The skin graft is a beneficial reconstructive technique for accelerating wound healing…
- Trial name
- NCT05907915
- Testing
- low level laser therapy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Skin Aging
Autologous Fibroblast Grafts in Facial Skin Regeneration
The purpose of this study is to evaluate the presence of skin changes after grafting of autologous fibroblasts by means of biophysical, histological, immunohistological, gene expression, glycosaminoglycan, and sensitivity…
- Trial name
- NCT01490554
- Testing
- autologous fibroblasts grafts
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Healthy Individuals, Diabetes
Heidelberg In Vivo Confocal Microscopy to Evaluate the Ocular Surface Disorders of Healthy and Diseased Individuals
In vivo confocal microscopy (IVCM) has been used in clinical settings for more than 25 years, and is noninvasive, rapid and easily repeatable technique to investigate ocular surface disorders.
- Conditions
- Healthy Individuals, Diabetes, Hypertension, Fabry Disease
- Trial name
- NCT04025801
- Where
- Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Graft Healing
Full-Thickness Skin Graft Sizing and Scar Quality
This study will compare three different full-thickness skin graft sizes (90%, 100%, and 110% of the surgical defect size) in patients undergoing reconstruction of nasal or ear surgical defects.
- Trial name
- NCT07896317
- Testing
- Full-Thickness Skin Graft Sizing
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Skin Pigmentation Over Contour Deformities of Face, Trauma, Rhomberg Disease
Long Term Effects on Skin Hyper Pigmentation With and Without Mesenchymal Stem Cell Enriched Adipose Tissue Grafting for "Contour Deformities With Pigmentary Changes on Face"
MSCs one injected along with fat, regulate pigmentation over the contour defects of face
- Trial name
- MSCs (NCT03564808)
- Testing
- MSC
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University
Skin Cancer, Basal Cell, Skin Cancer
A Comparison of Skin Grafts Versus Local Flaps for Facial Skin Cancer From the Patient Perspective: A Feasibility Study
A prospective single-centered feasibility study will be conducted. The purpose of the feasibility study is to define the variables to be included in a subsequent pilot study, assess the feasibility of conducting a prospective…
- Conditions
- Skin Cancer, Basal Cell, Skin Cancer, Skin Cancer, Non-Melanoma, Skin Cancers - Squamous Cell Carcinoma
- Trial name
- NCT04805905
- Testing
- FACE-Q patient reported outcome
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McMaster University
Wound
Juvidex (Mannose-6-Phosphate) in Accelerating the Healing of Split Thickness Skin Graft Donor Sites
The objective of this study is to compare the efficacy of two concentrations of Juvidex with placebo on the healing of split thickness skin graft donor sites
- Trial name
- NCT00664352
- Testing
- Mannose-6-Phosphate (Juvidex), Mannose-6-Phophate (Juvidex)
- Where
- United Kingdom
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Renovo
Diabetic Foot, Foot Ulcer; Diabetic
Study of Amniotic Membrane Graft in the Management of Diabetic Foot Ulcers
This is comparison trial comparing human amniotic membrane to standard wound care for non healing diabetic foot wounds over a 12 weeks period
- Trial name
- NCT02399826
- Testing
- Offloading, Dressing Application
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lower Extremity Institute for Research and Therapy
Diabetic Foot Ulcer
Omega3 Wound Fish Skin Graft in the Treatment of DFUs
The purpose of this clinical evaluation is to collect patient outcome data on a commercially available 510K FDA-approved product that is derived from minimal processing of Atlantic cod fish skin: KerecisTM Omega3 Wound.
- Trial name
- NCT04133493
- Testing
- Kerecis Omega3 Wound, Fibracol
- Where
- 5 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kerecis Ltd.
Burn Injury
Cardiovascular Responses in Burn Survivors During Exercise
This project will identify the efficacy of cooling modalities aimed to attenuate excessive elevations in skin and internal body temperatures, and associated indices of cardiovascular stress, during physical activity in…
- Trial name
- NCT06709781
- Testing
- Control (no cooling modalities), Water Spray
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center