Clinical trials: Skin Infections, Bacterial
Tinea Pedis, Athlete's Foot
Once a Day Topical Treatment for Athlete's Foot Fungus Inbetween the Toes in Males and Females
The topical cream, Sertaconazole (Ertaczo), has been FDA approved for the treatment of athlete's foot using twice a day dosing for 4 weeks.
- Conditions
- Tinea Pedis, Athlete's Foot, Foot Fungus, Ringworm
- Trial name
- NCT00856596
- Testing
- Sertaconazole nitrate cream 2%
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jamaica Hospital Medical Center
Hidradenitis Suppurativa (HS)
1726-nm Laser for Acne Inversa (Hidradenitis Suppurativa)
Hidradenitis suppurativa (HS) is a long-lasting skin condition that causes painful lumps, abscesses, and tunnels in areas such as the armpits and groin.
- Trial name
- WMCREI (NCT07155239)
- Testing
- AviClear Lase Treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wynn Medical Center
Fungal Infection, Inflammatory Skin Disease
Microbiota in Skin and Mucosa of Patients With Inflammatory Skin Diseases
The pathogeneses of many inflammatory diseases are not completely understood, yet, dysregulation of the human microbiota is increasingly being investigated as a possible contributing factor.
- Conditions
- Fungal Infection, Inflammatory Skin Disease, Yeast Infection Skin
- Trial name
- NCT04215458
- Testing
- sample collection (swap or tape strip)
- Where
- Denmark
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Coccidioidomycosis, Rheumatoid Arthritis
Risk of Coccidioidomycosis in Patients Receiving Anti-TNF and Other Biologic Agents for an Inflammatory Arthritis
The goal of the project is to study the risk of coccidioidomycosis (valley fever) in patients receiving anti-TNF and other biologic agents for inflammatory arthritis in Tucson, Arizona.
- Trial name
- NCT00796809
- Where
- United States
- Volunteers
- 598 people, healthy volunteers welcome
- Sponsor
- University of Arizona
HIV Infections, Chlamydia Trachomatis
Safety, Acceptability and Preliminary Effectiveness of PC-515 for Vaginal Use as a Possible Microbicide
The primary aims of the study were to assess the safety and acceptability of PC-515 when applied vaginally at least three times weekly for 12 months.
- Conditions
- HIV Infections, Chlamydia Trachomatis, Neisseria Gonorrhoeae, Trichomonas Vaginitis
- Trial name
- NCT00213031
- Testing
- Carraguard (PC-515)
- Where
- Thailand
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Population Council
Tinea Versicolor
A Study Comparing Ketoconazole Shampoo, 2% and Ketoconazole 2% Shampoo (RS) in the Treatment of Tinea Versicolor.
To demonstrate the efficacy, therapeutic equivalence and safety of Ketoconazole Shampoo, 2% (Taro Pharmaceuticals U.S.A., Inc.) and Ketoconazole 2% Shampoo (Reference Standard) in the treatment of tinea versicolor.
- Trial name
- NCT06305637
- Where
- United States
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Onychomycosis
Chart Review of the Efficacy of the GenesisPlus 1064 nm Nd:YAG Laser in the Treatment of Onychomycosis
The purpose of this study is to determine if toenail onychomycosis can be reduced by means of exposure to laser energy from the Cutera® GenesisPlus 1064 Nd:YAG laser system.
- Trial name
- NCT02445495
- Testing
- GenesisPlus 1064 nm Nd:YAG laser
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jason K Rivers, MD, FRCPC, FAAD
Ankle Injuries, Instability; Ankle (Ligaments) (Old Injury)
A Morphological Study in Volleyball Athletes With Cronic Ankle Instability
The former purpose of this study to investigate the effect of transverse abdominis, lumbar multifidus, vastus lateralis, lateral gastrocnemius, anterior talofibular ligament of morphology on explosive power and balance…
- Conditions
- Ankle Injuries, Instability; Ankle (Ligaments) (Old Injury), Radiological Devices Associated With Adverse Incidents, Diagnostic and Monitoring Devices, Athlete Foot
- Trial name
- NCT05746663
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Atopic Dermatitis, Psoriasis
Identification of Cutaneous and Blood Biomarkers Predictive of Response to Systemic Treatments During Chronic Inflammatory Skin Diseases
Chronic inflammatory skin diseases constitute a heterogeneous group of pathologies. They affect the skin but also other organs (joints, lungs, muscles, etc.). Their prognosis and response to treatments is extremely variable.
- Conditions
- Atopic Dermatitis, Psoriasis, Hidradenitis Suppurativa, Lichen Planus
- Trial name
- ImmuneSkinBank (NCT06599411)
- Testing
- Sampling
- Where
- France
- Volunteers
- 830 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hidradenitis Suppurativa, Periodontal Diseases
Hidradenitis Suppurativa and Periodontal Diseases
Hidradenitis suppurativa or Verneuil's disease (HS) is a neglected and often overlooked chronic inflammatory skin disease. Nevertheless, it is frequent (1% of the general population) and deeply affects quality of life in patients…
- Trial name
- HSPDA (NCT03553888)
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Athlete Foot
Neurodynamics to Improve Jump Functionality in Trampoline Jump Gymnasts
The goal of neurodynamics is to restore homeostasis of peripheral nerves. In the current context there is varied evidence that links neurodynamics with clinical pain treatments or different pathologies, but little evidence…
- Trial name
- NCT04289857
- Testing
- Neurodynamic training
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Onychomycosis, Chronic Paronychia
A Pilot Study - Safety and Efficacy of Nailprotex® for Onychomycosis Treatment
This study was designed to demonstrate the efficacy of this product in non-dermatophyte (Scytalidium dimidiatum) onychomycosis and chronic paronychia treatment in Thai patients.
- Trial name
- NCT02464826
- Testing
- Nailprotex
- Where
- Thailand
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Non-dermatophyte Onychomycosis
Comparison Between Long-pulsed Nd:YAG, Amorolfine and Combination Treatment in Treating Non-dermatophyte Onychomycosis
This study aims to compare the efficacy and safety of amorolfine, long-pulsed Nd:YAG laser and the combination between amorolfine and long-pulsed Nd:YAG in treating the non-dermatophyte and mixed-infection onychomycosis.
- Trial name
- NCT02812043
- Testing
- 1,064nm Long-pulsed Nd:YAG, Amorolfine
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Tinea Pedis
Nitric Oxide Releasing Solution (NORS) Footbath to Treat Athlete's Foot
The purpose of this study is to determine the fungicidal efficacy of nitric oxide releasing solution footbath and it's effect on the clinical signs and symptoms associated with Tinea Pedis
- Trial name
- NCT02871011
- Testing
- Nitric Oxide, Water
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nitric Solutions Inc.
Rheumatoid Arthritis, Polyarticular Juvenile Idiopathic Arthritis
Comparison of PK and Tolerability of MSB11022 Administered by AI or PFS
The primary objective of this study is to demonstrate equivalence of the pharmacokinetic (PK) profile of MSB11022 administered by either an auto-injector (AI) or a pre-filled syringe (PFS) as single subcutaneous (s.c.) injection…
- Conditions
- Rheumatoid Arthritis, Polyarticular Juvenile Idiopathic Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis
- Trial name
- NCT04018599
- Testing
- 40 mg MSB11022
- Where
- 2 sites in United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Fresenius Kabi SwissBioSim GmbH
Acute Bacterial Skin and Skin Structure Infection (ABSSSI), Prosthetic Joints Infection (PJI)
Phase 1, Single-Dose and Multiple-Dose Continuous Intravenous Infusions of TNP-2092 for Injection in Healthy Chinese Participants
This is a phase 1, single-center, randomized, double-blind, placebo-controlled, dose-escalation clinical trial of single and multiple intravenous doses of TNP-2092 for injection in healthy Chinese participants.
- Trial name
- NCT06394518
- Testing
- TNP-2092 for injection
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- TenNor Therapeutics Inc.
Hyperthermia
Infrared Bioeffect System for the Treatment of Onychomycosis
Onychomycosis is a common nail plate infection caused by dermatophytes, non-dermatophytic molds, and yeasts. The disease is difficult to achieve self-healing and predisposed to secondary bacterial infections.
- Trial name
- NCT06036654
- Testing
- infrared thermotherapy instrument
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gao Xinghua
Onychomycosis, Dermatophytosis
Study Evaluating the Effect of Jublia on Dermatophytomas
This study will examine how Jublia affects dermatophytomas, which are difficult to treat with other therapeutic options.
- Trial name
- NCT03098615
- Testing
- Jublia (Efinaconazole 10% Topical Solution)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Hidradenitis Suppurativa
The Ohio State University Dermatology Biorepository
This study will create and extend a source of clinical specimens for the future study of inflammatory skin disorders.
- Trial name
- NCT03146676
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Onychomycosis
Evaluation of a Combination of Two Medical Devices and One Device Use in the Treatment of Toenail Onychomycosis
The goal of this clinical investigation is to evaluate the efficacy of the tested products in medium to moderate onychomycosis after 112 days of treatments.
- Trial name
- NCT06175013
- Testing
- Sérum PURIFIANT, Sérum PURIFIANT in association Sérum BOOSTER
- Where
- Mauritius
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Swiss Footcare Laboratories - Poderm Professional