Clinical trials: Skin Injury
Venous Leg Ulcer
Randomized Controlled Trial for Treatment of Pain and Assessment of Wound Healing in Chronic Venous Leg Ulcers Using Near Infrared Laser Therapy
The laser emits an infrared light that heats the skin and underlying tissues with the purpose of temporary relief of minor muscle and joint pain, as well as stiffness associated with arthritis.
- Trial name
- NCT03716167
- Testing
- Summus Laser
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Acute Standardized Cutaneous Wounds (Punch-biopsy Wounds)
Topical GHK-Cu Gel for Acute Skin Wound Healing
This study will evaluate whether a topical gel containing GHK-Cu (a copper(II)-peptide complex) can safely speed up healing of small, standardized skin wounds in healthy adults compared with a matching vehicle gel.
- Trial name
- CuHeal (NCT07437586)
- Testing
- GHK-Cu Gel (Copper(II)-peptide complex)
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hudson Biotech
Liver Transplantation
A New Prediction Mode for Predicting the Risk of Pressure Injury in Patients Undergoing Liver Transplantation
Pediatric population is at a high-risk of pressure injury (PI). Patients undergoing liver transplantation are more prone to PIs compared with other types of surgery.
- Trial name
- PMPRPIULT (NCT05588271)
- Testing
- Exposures
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Surgical Site Infection (SSI)
Skin Adhesive Plus Intra-cuticular Suture Versus Suture Alone for Cesarean Skin Closure
The goal of this randomized control trial is to compare two skin closure techniques after cesarean section. Both techniques are currently in wide use but no comparison between the two was reasserted yet.
- Trial name
- NCT07483411
- Testing
- Dermabond
- Where
- Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Doron Kabiri
Sunburn, Ultraviolet Radiation Exposure
Test of Interventions to Prevent Skin Cancer Among Danes on Vacation in High UV Index Sunny Destinations
The aim of the study is to test a series of developed effective interventions targeting Danes going on vacation to sunny destinations to decrease sunburn by increasing use of shade, hats, protective clothing, and sunscreen to…
- Conditions
- Sunburn, Ultraviolet Radiation Exposure, Skin Cancer, Malignant Melanoma
- Trial name
- NCT03607578
- Testing
- Other: Control Group - Minimal Intervention, Experimental: Protection Routine 1, Experimental: Protection Routine 2
- Where
- Denmark
- Volunteers
- 1,548 people, healthy volunteers welcome
- Sponsor
- Brian Køster
Knowledge, Satisfaction
Deep Learning Model Detecting Pressure Injury
In the health care system, pressure injuries, which are among the quality indicators, are a serious patient safety problem that affects the length of hospital stay and the cost of care.
- Trial name
- NCT06641258
- Testing
- Control Group (Standard Procedure), Experimental Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Pressure Injury, Military Activity
Pressure Injury Prevention in AE and PFC
This study evaluates the effect of a multilayer skin dressing (Mepilex) placed on the sacrum or a fluid filled pad (LiquiCell) on risk factors for pressure injuries under conditions consistent with military long-distance…
- Trial name
- NCT03924622
- Testing
- Mepilex, LiquiCell
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Washington
Diabetic Foot Ulcer, Wound Healing
Tele-Exercise Platform for Plantar Wound Healing
The purpose of the study is design and use a telemedicine platform which integrates video-chat, pre-programmed interactive game-based foot, and ankle exercise modules, and real-time quantitative performance metrics displayed to…
- Conditions
- Diabetic Foot Ulcer, Wound Healing, Wound Care
- Trial name
- Tele-FootX (NCT06439667)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Wound Healing
Safety and Efficacy of Topical TolaSure on Skin Punch Biopsies in Healthy Participants
TolaSure is a topical gel for the promotion of wound healing. This phase I study will assess the safety, tolerability and clinical effect of TolaSure when applied to skin wounds created by punch biopsy in healthy participants.
- Trial name
- NCT03620175
- Testing
- TolaSure Topical Gel
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- BioMendics, LLC
Pressure Injury, Orthopedic Surgery
The Effect of Pressure Wound Care Package on the Development of Operating Room Pressure Wound in Orthopedic Surgery
SUMMARY In a non-randomised (quasi-experimental) clinical study, it was aimed to determine the effect of the care package applied in the early postoperative period on operating theatre pressure sores, pain, fear of falling and…
- Trial name
- NCT05852236
- Testing
- Assigned Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Sehitkamil Devlet Hastanesi
Androgenetic Alopecia
Split Wound Comparison of Trichophytic Closure Techniques for Donor Site in Hair Transplantation
This study aim to compare cosmetic results between 3 trichophytic closure techniques for donor site (the trimming of upper, lower and both edge of linear incision) in hair transplantation.
- Trial name
- NCT01655602
- Testing
- Trichophytic closure upper edge trimming, Trichophytic closure lower edge trimming, Trichophytic closure both edge trimming
- Where
- Thailand
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Proteinuria, Kidney Injury
Inflammatory and Immune Profiling of Kidney Tissue Obtained From Patients With Newly Diagnosed Kidney Disease
This study will evaluate in patients with kidney disease, the role that certain inflammatory and immune mediators play in promoting kidney damage.
- Conditions
- Proteinuria, Kidney Injury, Chronic Kidney Disease
- Trial name
- NCT01156428
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- The Rogosin Institute
Episiotomy Wound
Steristrips Adhesive Tape Versus Subcuticular Suture for Episiotomy Repair in Primigravid Obese Women
This study will be done to question the superiority of using skin adhesive tape (® Steri-Strip) closure in wound pain and healing over the traditional running absorbable subcuticular suture technique in perineal repair after…
- Trial name
- NCT03702751
- Testing
- Adhesive tape, Continuous subcuticular skin suturing
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Visible Difference, Acceptance and Commitment Therapy
Acceptance-based Self-help for Individuals With Visible Difference and Social Anxiety
The acceptance and commitment therapy (ACT) model theoretically fits with treating appearance-related anxiety in individuals with a visible difference.
- Conditions
- Visible Difference, Acceptance and Commitment Therapy, ACT, Skin Condition
- Trial name
- NCT03205839
- Testing
- Acceptance-based self-help intervention
- Where
- United Kingdom
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Ultraviolet Rays; Injury, DNA Adduct Formation
Quantification of DNA Repair Products in the Urine After Ultraviolet Radiation of the Skin
Purpose of the experiment The investigators know that DNA damage is formed in the skin by sun exposure of the thymine-dimer type. Many of these injuries are repaired and excreted through the urine.
- Conditions
- Ultraviolet Rays; Injury, DNA Adduct Formation, DNA Damage, Radiation Induced, DNA Damage
- Trial name
- NCT05277961
- Testing
- Ultraviolet radiation
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Surgical Site Infection
Efficacy Study to Evaluate Antimicrobial Effectiveness of ZuraPrep™
The purpose of this pilot study is to evaluate antimicrobial properties of a single test product, a vehicle product and a reference product applied in two different areas when used as a patient preoperative skin preparation.
- Trial name
- ZX-ZP-0035 (NCT02221232)
- Testing
- Chloraprep, ZuraPrep, ZuraPrep Vehicle
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Osteoporosis
Danish Osteoporosis Prevention Study
Hypothesis: Use of hormone replacement therapy (HRT) decreases the incidence of fractures in early postmenopausal women. The project was initiated in 1990, and the inclusion ended in 1993.
- Trial name
- NCT00252408
- Testing
- Hormone replacement therapy
- Where
- Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pressure Injury
The Effect of Norepinephrine on the Development of Pressure Injury
Norepinephrine mainly increases mean arterial pressure among intensive care patients. It may be an essential risk factor in developing pressure injuries. However, there are still conflicting findings in the literature.
- Trial name
- NCT06860308
- Where
- Turkey (Türkiye)
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- Koç University