Clinical trials: Skin Irritation
Skin Irritability
Dermatological Evaluation of Topical Compatibility, Primary Skin Irritability, Accumulated Skin Irritability, and Dermal Sensitisation
Check the safety under normal conditions of use through the verification of emergence signs of irritability and sensitisation of the genital mucosa.
- Trial name
- DERM EV TOPIC (NCT02419248)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Kley Hertz S/A
Irritation/Irritant, Sensitisation
Human Skin Safety Testing of a Mitopure Topical Product Using a Human Repeat Insult Patch Test (HRIPT) in Healthy Volunteers
The objective of this study is to investigate the irritation and sensitization potential of multiple topically applied test articles (containing different concentrations of Mitopure), in a shared panel of healthy volunteers by…
- Trial name
- GLOW-Safety (NCT05079607)
- Testing
- Mitopure Topical Formula 1, Mitopure Topical Formula 2
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Dermatitis, Atopic
Skin Irritation Study of GSK2894512 Cream
GSK2894512 is a novel anti-inflammatory agent that is currently under development for the topical treatment of atopic dermatitis and chronic plaque psoriasis.
- Trial name
- NCT02637206
- Testing
- GSK2894512 Cream, Vehicle Cream, Empty Patch
- Where
- Japan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Radiation-induced Dermatitis
Study of ST266 Versus Saline in Treating Skin Irritation From Radiation
The objective of this study is to evaluate the safety and efficacy of ST266 in treating radiation burns of the skin in patients undergoing treatments for breast cancer and to compare ST266 treated burns with those treated with…
- Trial name
- NCT01714973
- Testing
- ST266
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Noveome Biotherapeutics, formerly Stemnion
Cumulative Irritation
14-Day Cumulative Irritation Patch Test in Subjects With Normal Skin
The objective of this study is to determine the ability of the study material to cause irritation to the skin of humans under controlled patch test conditions.
- Trial name
- NCT02309294
- Testing
- Novel lubricant Miami w/ fragrance, Novel lubricant Miami no fragrance, KY Liquid lubricant
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Irritation/Irritant, Sensitisation
Human Skin Safety Testing of 1 Mitopure Topical Products Using a Human Repeat Insult Patch Test (HRIPT) in Healthy Volunteers
The objective of this study is to investigate the irritation and sensitization potential of 1 topically applied test article containing Mitopure in a shared panel of healthy volunteers by means of repeated cutaneous patch…
- Trial name
- GLOW-Safety-4 (NCT07517874)
- Testing
- Mitopure Topical Formula 11
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Atopic Dermatitis
Safety and Efficacy Study of ImCOOH Cream in Patients Suffering From Moderate Atopic Dermatitis
Atopic dermatitis is one of the most common skin diseases, with a lifetime prevalence of up to 20%, and an increasing number of cases.
- Trial name
- NCT00583895
- Testing
- 10% ImCOOH cream
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Valletta Health B.V.
Healthy
A 21 Day Irritation Study in Healthy Volunteers With Diacerein 1% Ointment
Single center, randomized, controlled, evaluator blinded, within-subject study to evaluate the irritation potential of diacerein1% ointment on normal skin of healthy volunteers, using a cumulative irritancy patch test (CIPT)…
- Trial name
- NCT03472534
- Testing
- diacerein 1% ointment
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Castle Creek Pharmaceuticals, LLC
Acne Vulgaris
A Study to Evaluate the Irritation Potential of Tazarotene Foam on Skin in Healthy Volunteers
The purpose of this study is to evaluate the irritation level of tazarotene foam after 21 days of exposure on the skin of healthy volunteers.
- Trial name
- NCT01112787
- Testing
- Tazarotene Foam, Vehicle Foam, Sodium Laural Sulfate
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Skin Irritability, Skin Sensitization
Safety Dermatological Assessment of Topical Use Product Through Dressings Predictive Studies for Evaluation of Photoirritation and Dermal Photosensitivity
The purpose of this study is to prove the product tested does not cause photoirritation or photosensitization reactions when exposed to sun light.
- Trial name
- SAF DER ASSESS (NCT02441608)
- Testing
- KL029 Intimate Lubricant Gel
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Kley Hertz S/A
Skin Barrier to Water Loss, Skin Health
Apple Peptide Complex for Post-Surgical and Aesthetic Skin Recovery
This clinical study evaluates a topical botanical formulation for supporting skin recovery following invasive and non-invasive aesthetic procedures.
- Conditions
- Skin Barrier to Water Loss, Skin Health, Skin Discoloration, Skin Irritation
- Trial name
- APC-SKIN (NCT07807085)
- Testing
- Apple Peptide Complex Post-Aesthetic Care Protocol
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Grow Out Oils Clinical Aromatherapy Company
Skin Care
Evaluation of Skin Irritancy and Sensitization of a Liquid Bandage
The investigational product constitutes a medical device that is freely accessible to consumers and, as such, must be safe under real or reasonably foreseeable conditions of use and its safety must be tested before being placed…
- Trial name
- NCT05876546
- Testing
- Liquid bandage, Saline Solution
- Where
- 2 sites in Brazil
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Eurofarma Laboratorios S.A.
Atrophic Vaginitis
A Comparison of Estradiol Vaginal Cream to Estrace® Cream in 350 Postmenopausal Females With Atrophic Vaginitis
The purpose of this study is to determine the therapeutic equivalence of Mylan's estradiol vaginal cream to Estrace® cream and superiority of both products to placebo.
- Trial name
- NCT02195986
- Testing
- Estradiol Vaginal Cream, 0.01%, Estrace® 0.01% cream
- Where
- 21 sites in United States
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Acne Vulgaris
Evaluation of Irritation by Two Facial Gels Applied to Opposite Sides of the Face
A study to compare the skin irritation potential of two marketed gels for acne treatment, each applied to half of the face of healthy volunteers.
- Trial name
- NCT00919191
- Testing
- Tretinoin gel, Adapalene and Benzoyl peroxide
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Sensitivity, Contact
Dermatological Assessment of Primary Dermal Irritability Accumulated and Sensitization
This is a clinical study for health care product safety assessment. The research will be conducted with 92 subjects, aged 18 to 59 years.
- Trial name
- NCT04248556
- Testing
- Health care product
- Where
- Brazil
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Herbarium Laboratorio Botanico Ltda
Skin Irritation
Repeat Insult Patch Test of Skin Irritation/Sensitization for Cetaphil Dermacontrol Oil Control Moisturizer SPF 30
Determine if Cetaphil DermaControl Oil Control Moisturizer SPF 30 proves to be a contact sensitizer or irritant in certain individuals
- Trial name
- NCT01887808
- Testing
- Cetaphil DermaControl Oil Control Moisturizer SPF 30
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Pain
A Safety Study to Investigate the Skin Irritancy Potential of Diclofenac-Menthol Gel
This research study is being conducted to investigate the skin irritancy potential of a new medication which contains two active ingredients (diclofenac and menthol) together in a gel formulation and is being developed to treat…
- Trial name
- NCT02169154
- Testing
- 1% Diclofenac Sodium, 3% Menthol, 0.09% Menthol
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Hypersensitivity
Study to Determine Skin Irritation Potential of an Antifungal Cream Containing Trolamine After Repeated Skin Application (Cumulative Irritation Patch Test)
In this study researchers want to study the potential skin reaction after repeated application of an antifungal cream containing trolamine.
- Trial name
- NCT04531813
- Testing
- Butenafine HCl 1% (BAY1896425), Positive Control-Sodium lauryl sulfate (SLS), Negative Control
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bayer
Hygiene
Lactacyd Radiance (Lactic Acid) Prophetic Patch Test
Primay objective: To evaluate the potential of the products in eliciting adverse skin reaction.
- Trial name
- NCT00679562
- Testing
- Lactic Acid, Distilled water
- Where
- Thailand
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sanofi
Skin Lesion, Skin Lesions
Assessment of EF192A Potential Sensitization and Accumulated and Primary Irritability in Controlled/Maximized Conditions
The investigational product constitutes a medical device that is freely accessible to consumers and, as such, must be safe under real or reasonably foreseeable conditions of use and its safety must be tested before being placed…
- Conditions
- Skin Lesion, Skin Lesions, Skin Care
- Trial name
- Spray A (NCT06731062)
- Testing
- EF192A, Saline solution
- Where
- Brazil
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Eurofarma Laboratorios S.A.