Clinical trials: Skin Irritation
Sensitivity, Contact
Dermatological Assessment of Primary Dermal Irritability Accumulated and Sensitization
This is a clinical study for health care product safety assessment. The research will be conducted with 92 subjects, aged 18 to 59 years.
- Trial name
- NCT04248556
- Testing
- Health care product
- Where
- Brazil
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Herbarium Laboratorio Botanico Ltda
Skin Manifestations
Standard TDS Irritation Study: Trained Skin Grader vs. Digital Imaging
The purpose of this study is to (1) collect trained observer scores and digital images of skin irritated by generic and RLD Lidocaine 5% delivered via TDS, and (2) assess performance of an automated system for predicting scores…
- Trial name
- TDS_TSG_DI (NCT02787356)
- Testing
- TDS Lidocaine 5%; generic, TDS Lidocaine 5%; RLD
- Volunteers
- healthy volunteers welcome
- Sponsor
- SRI International
Acne Vulgaris
A Study That Evaluates the Decrease in Irritation When Using Additional Acne Treatment Products
This study is to see if there's any difference in the amount of facial irritation when two acne products are used together on one side of the face, compared to one acne treatment product used alone on the other side of the face.
- Trial name
- NCT01313728
- Testing
- Dapsone plus Tretinoin Gel, Tretinoin Gel
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Dermatitic Reaction of Face
Skin Irritation Test of Ten Products
Evaluation of cutaneous tolerance of ten products by primary irritant patch test
- Trial name
- NCT05245383
- Testing
- ten products (S01~S10) and two blank (BK1, BK2)
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Skin Irritability
Dermatological Evaluation of Topical Compatibility, Primary Skin Irritability, Accumulated Skin Irritability, and Dermal Sensitisation
Check the safety under normal conditions of use through the verification of emergence signs of irritability and sensitisation of the genital mucosa.
- Trial name
- DERM EV TOPIC (NCT03007498)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Kley Hertz S/A
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Skin and Connective Tissue Diseases
Skin Irritation Test of LEO 80185 Gel in Healthy Japanese Subjects
The purpose of the study is to investigate skin irritation of LEO 80185 gel, gel vehicle and Liquid Paraffin in healthy Japanese male subjects.
- Trial name
- NCT02379793
- Testing
- LEO 80185 gel, vehicle, liquid paraffin
- Where
- Japan
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- LEO Pharma
Tissue Adhesives
Quantifying Adhesive Residue on Skin Following Removal of Maxillofacial Prosthetic Adhesives: An In Vivo Study
This pilot interventional in vivo study aims to quantitatively evaluate and compare the amount of adhesive residue left on the skin following removal of extraoral maxillofacial prosthetic adhesives.
- Trial name
- ARMS (NCT07647458)
- Testing
- Secure Adhesive Regular,, Secure Adhesive Extra Strength, Daro Adhesive Regular
- Where
- India
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Amrita Vishwa Vidyapeetham
Dermatitis, Contact, Dermatitis, Occupational
Efficacy of Glycerol, Two Topical Steroids, and a Topical Immune Modulator Against Skin Irritation
The purpose of this study is to compare the efficacy of glycerol ointment, triamcinolone acetonide ointment, clobetasol ointment and tacrolimus ointment on irritated skin in a cumulative skin irritation test model using healthy…
- Trial name
- WA+TR_1 (NCT00779792)
- Testing
- clobetasol, triamcinolone acetonide, tacrolimus
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Pain, Healthy Volunteers
A Study to Learn About Whether BAYH006689 Causes Skin Irritation When Applied as a Topical Gel in Healthy Participants
Researchers are looking for a better way to treat muscle and joint pains. Researchers have seen that medicines which help reduce pain and inflammation could be safer when applied directly to the skin, called topical application…
- Trial name
- NCT06511973
- Testing
- Naproxen (BAYH006689), A solution of 0.9% Saline, A solution of 0.2% SLS
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Bayer
Constipation-predominant Irritable Bowel Syndrome
Cheno Effect on Transit in Health and IBS-C
The study hypothesis is that the naturally occurring bile acid, chenodeoxycholic acid, induces acceleration of colonic transit in health and in patients with constipation-predominant Irritable Bowel Syndrome (IBS-C).
- Trial name
- Chenotransit (NCT00912301)
- Testing
- Sodium chenodeoxycholate (NaCDC)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Healthy
Cumulative Irritation Test of PAC-14028 in Healthy Volunteers
The purpose of this study is to determine the cumulative irritation potential of the products listed by the Sponsor.
- Trial name
- NCT01638117
- Testing
- PAC14028-Vehicle, PAC14028-0.1, PAC14028-0.3
- Where
- South Korea
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Amorepacific Corporation
Acne Vulgaris, Allergic Rhinitis
MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use
The specific aim of this proposed pilot study is to compare two standardized processes (paper and electronic) to deliver a customized MedlinePlus health information prescription.
- Conditions
- Acne Vulgaris, Allergic Rhinitis, Anxiety, Asthma
- Trial name
- NCT01050465
- Testing
- health information prescription
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Osteoporosis, Postmenopausal
A Multiple-Dose Study to Evaluate Skin Irritation and Sensitization of Teriparatide Administered Transdermally in Healthy Postmenopausal Women
This study is a Phase 1, multi-center, 2-part, subject- and investigator-blind, randomized, placebo-controlled, multiple dose study of transdermal teriparatide (80-µg dose) in healthy postmenopausal women.
- Trial name
- NCT01250145
- Testing
- LY333334
- Where
- 5 sites in United States, Germany and 1 more
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
IBS - Irritable Bowel Syndrome
The Prevalence of Irritable Bowel Syndrome Using Rome IV Criteria in Medical Student and The Related Factors
A cross-sectional study of 350 medical student Universitas Indonesia from first grade until fifth grade was done during November-December 2016. This study used stratified randomized sampling.
- Trial name
- IBS (NCT03178877)
- Testing
- No intervention
- Where
- Indonesia
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Psoriasis
A Study to Evaluate the Irritation Potential of GSK2894512 Cream on Skin in Healthy Subjects
This study is conducted to assess the potential of topically-applied GSK2894512 cream at 3 concentrations (0.5%, 1%, and 2%) to induce skin irritation at the site of application in healthy subjects.
- Trial name
- NCT01984775
- Testing
- GSK2894512 cream, Vehicle cream, Positive control
- Where
- 2 sites in United States, Germany
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Hygiene
Lactacyd Radiance (Lactic Acid) Prophetic Patch Test
Primay objective: To evaluate the potential of the products in eliciting adverse skin reaction.
- Trial name
- NCT00679562
- Testing
- Lactic Acid, Distilled water
- Where
- Thailand
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sanofi
Irritation/Irritant, Sensitisation
Human Skin Safety Testing of Mitopure Topical Products Using a Human Repeat Insult Patch Test (HRIPT) in Healthy Volunteers
The objective of this study is to investigate the irritation and sensitization potential of multiple topically applied test articles (containing different concentrations of Mitopure), in a shared panel of healthy volunteers by…
- Trial name
- GLOW-Safety-2 (NCT06884215)
- Testing
- Mitopure Topical Formula 3, Mitopure Topical Formula 4
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Healthy Volunteers
A Study to Evaluate Skin Irritation and Photo Irritation of JNJ 10229570-AAA on Intact Skin of Japanese Healthy Male Participants
The purpose of this study is to evaluate skin irritation and photo irritation of JNJ 10229570-AAA on intact skin of Japanese healthy male participants.
- Trial name
- NCT01494714
- Testing
- JNJ 10229570-AAA 1.2% cream, JNJ 10229570-AAA 2.4% cream, JNJ 10229570-AAA 3.6% cream
- Where
- 2 sites in Japan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Janssen Pharmaceutical K.K.
Cumulative Irritation and Sensitization
Study Will Assess Skin Irritation and Sensitization for HP-1050 Patch
A randomized, evaluator-blinded study to assess skin irritation and skin sensitization of HP-1050 transdermal system (HP-1050) in comparison to XULANE patch in healthy female volunteers.
- Trial name
- NCT04624867
- Testing
- HP-1050 Patch
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Noven Pharmaceuticals, Inc.