Clinical trials: Skin Microbiome
Non Small Cell Lung Cancer, Microbiome
BioForte Technology for in Silico Identification of Candidates for a New Microbiome-based Therapeutics and Diagnostics
The goal of the project is to develop and validate the BioForte technology. Its main functionality should be to in silico determine candidates for novel microbiome-based therapeutics and diagnostics.
- Conditions
- Non Small Cell Lung Cancer, Microbiome, Metagenome, Immunotherapy
- Trial name
- NCT04136470
- Testing
- Collection of stool, blood (PBMC) and biopsy (FFPE)
- Where
- 10 sites in Poland
- Volunteers
- 130 people
- Sponsor
- Ardigen
Gastrointestinal Health
Colostrum and Gut Health
The primary objective of this study is to evaluate changes in participant-reported gastrointestinal function over a 16-week intervention period and a 4-week non-supplementation period (20 weeks total) following daily consumption…
- Trial name
- NCT07856979
- Testing
- Bovine Colostrum - Lower Dose, Bovine Colostrum - Higher Dose
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Bovita Labs, LLC
Healthy Volunteers
Evaluation of Changes to Skin Microbiome With Tape-Stripped Wounds
This single center, randomized, 15-day clinical trial is being conducted to assess the changes to the skin microbiome of induced wounds on the back in approximately 35 healthy adult subjects aged 18-55 years, with Fitzpatrick…
- Trial name
- NCT03365934
- Testing
- ADHESIVE BANDAGE #1, ADHESIVE BANDAGE #2, ADHESIVE BANDAGE #3
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Acne Vulgaris
A Botanical Skin Care Regimen on Mild to Moderate Acne and the Microbiome
The purpose of this study is to analyze changes in acne and changes in the gut and skin microbiome with the use of a multi-step botanical skin care regimen in those with mild to moderate acne.
- Trial name
- NCT05271487
- Testing
- Multi-Step Botanical Skin Care Regimen
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Papulopustular Rosacea
Evaluation of Topical Encapsulated Benzoyl Peroxide on the Skin Microbiome and Skin Biophysical Properties
The overall objective of this study is to assess how the use of the drug may shift the skin microbiome and skin biophysical properties.
- Trial name
- NCT05675501
- Testing
- Encapsulated Benzoyl Peroxide Cream
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Sol-Gel Technologies, Ltd.
Skin Microboime, Acne
Study of Skin Balancing Gel Cream Safety and Influence of Skin Microbiome on Acne Prone Skin
The purpose of this study is to assess the safety of the skin balancing gel cream and examine the effects it has on the skin microbiome of individuals with non-cystic acne prone skin.
- Trial name
- NCT05941065
- Testing
- Balancing gel cream
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Diaper Rash
Infant Microbiome in Diaper Rash
The objective of this study is to evaluate the microbiome composition of infant's (9-12 month) skin experiencing diaper rash in order to determine if the onset and severity of erythema associated with diaper rash is influenced by…
- Trial name
- NCT02893501
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Kimberly-Clark Corporation
Incontinence-associated Dermatitis
Reducing Skin Surface pH During Skin Occlusion: Changes to Skin Microbiome and Skin Parameters
The main aim of this exploratory research study is to investigate how exposure to a material with low pH affects the skin microbiome and skin parameters.
- Trial name
- NCT06363786
- Testing
- Test patches
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Essity Hygiene and Health AB
Skin Aging, Hair Care
A Pilot Study to Evaluate the Expanded Reach of Decentralized Digital Skin Health Clinical Studies
This is a randomized, decentralized, non-interventional clinical study. The primary objective of this study is to develop execution and efficiency metrics from completion of this study to inform on the potential design for future…
- Conditions
- Skin Aging, Hair Care, Skin Microbiome
- Trial name
- NCT07193290
- Testing
- Lifestyle Questionnaire, Self-portrait image (Face and Hair), Skin microbiome collection
- Where
- United States
- Volunteers
- 1,027 people, healthy volunteers welcome
- Sponsor
- Kenvue Brands LLC
Microbiome
Evaluation of Two Regimens, With Healthy Male and Female Babies, Ages 3-6 Months Old, Using Various Assessments.
This study is to assess the impact of two skincare regimens on the cutaneous microbiome and skin physiology of healthy male and female infants, ages 3-6 months using clinical, instrumental, D-Squame tape, microbiome and parental…
- Trial name
- Microbiome (NCT03457857)
- Testing
- Cleanser, Cleanser and Lotion
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Atopic Dermatitis
Continued Safety Evaluation of FB-401 in Children, Adolescents and Adults (2 Years and Older) With Mild to Moderate Atopic Dermatitis Previously Enrolled in the FB401-01 Study
The purpose of this study is to evaluate the continued safety and tolerability of FB-401 in subjects 2 years of age or older with mild to moderate atopic dermatitis.
- Trial name
- NCT04936113
- Testing
- FB-401
- Where
- 8 sites in United States
- Volunteers
- 36 people
- Sponsor
- Forte Biosciences, Inc.
Skin Microbiome, Undercast Materials
Observational Study to Evaluate the Influence of Undercast Material Types on Skin Microbiome
This clinical study will evaluate the clinical performance and the safety of the CE-marked casting and padding materials when used in routine fracture care without any additional invasive methods and within the intended use.
- Trial name
- Microbiome II (NCT05347927)
- Testing
- water resistante padding, non water resistante padding
- Where
- 3 sites in Netherlands
- Volunteers
- 108 people
- Sponsor
- BSN Medical GmbH
Microbiota, Eczema
Infant Restore: Efficacy of Microbiome Analysis and Education
The goal of this clinical trial is to learn if a microbiome analysis, education, and recommendation program can improve gut health, reduce future health risks, and empower parents in their children's health in infants aged 0-3…
- Conditions
- Microbiota, Eczema, Microbiome, Gut Microbiome
- Trial name
- NCT06424691
- Testing
- Tailored Recommendations, Consult Call, Email Series
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Seeding Inc
Acne Vulgaris
Oral Probiotics on the Microbiome and Lipidome in Acne Vulgaris
The purpose of this study is to determine how probiotics affect sebum production and gut health in those with acne vulgaris.
- Trial name
- NCT04596748
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Hair Thinning
The Effects of an Oral Hair Supplement on Hair Density, Growth, and Microbiome
The purpose of this study is to assess how an oral herbal supplement influences hair density, shine, growth, and microbiome.
- Trial name
- NCT06146166
- Testing
- Oral herbal supplement
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Atopic Dermatitis
Evaluation of FB-401 in Children, Adolescents and Adults (2 Years and Older) With Mild to Moderate Atopic Dermatitis
The purpose of this study is to evaluate the potential improvement in atopic dermatitis signs and symptoms following the application of FB-401 in patients 2 years or older with mild to moderate atopic dermatitis.
- Trial name
- NCT04504279
- Testing
- FB-401
- Where
- 15 sites in United States
- Volunteers
- 154 people
- Sponsor
- Forte Biosciences, Inc.
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Microbiota
Clinical Trial to Assess the Effects of Topical Lotions on Changes in the Skin Microbiome and Associations With Itch
This was a multi-center, 14-day clinical use study with a 7-day regression period, being conducted to assess the changes in the skin microbiome with two moisturizers in female and male subjects 16-50 years of age with mild to…
- Trial name
- NCT03673059
- Testing
- OTC Eczema Moisturizer Regimen, Cosmetic Moisturizer Regimen
- Where
- 2 sites in United States
- Volunteers
- 91 people
- Sponsor
- Johnson & Johnson Consumer Products Company Division of Johnson & Johnson Consumer Companies, Inc.
Sensitive Skin
A Clinical Investigation of a Topical Moisturizer on Skin Barrier Function in Adults With Sensitive Skin
The purpose of this research study is to evaluate whether a marketed moisturizing cream can improve skin barrier function (how well the outer layer of the skin keeps moisture in and protects the skin), skin hydration, skin…
- Trial name
- NCT07811531
- Testing
- White petrolatum, Investigational moisturizer
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Good Molecules, LLC
Acne Vulgaris, Acne
Safety, Tolerability, and Immunogenicity of ORI-A-ce001 for the Treatment of Acne Vulgaris
Acne vulgaris, or acne, is one of the most prevalent diseases worldwide, with skin conditions being one of the top causes of years lived with disability and non-fatal disease burden.
- Trial name
- OREA (NCT05131373)
- Testing
- ORG101 - Experimental 1
- Where
- 6 sites in Germany
- Volunteers
- 38 people
- Sponsor
- Sanofi Pasteur, a Sanofi Company