Clinical trials: Skin Physiology
Cancer-related Fatigue, Breast Cancer
Telehealth Exercise Program Evaluating Fatigue and Physical Function in Rural Cancer Survivors
This study investigates the efficacy of a telehealth exercise program designed specifically for rural cancer survivors with cancer-related fatigue (CRF).
- Conditions
- Cancer-related Fatigue, Breast Cancer, Prostate Cancer
- Trial name
- NCT07001241
- Testing
- Telehealth Exercise Program
- Where
- 2 sites in United States
- Volunteers
- 134 people
- Sponsor
- University of Colorado, Denver
Breast Cancer, Breast Cancer Female
Lymphedema Severity on Shoulder Joint Function and Muscle Activation Patterns in Breast Cancer Survivors
Breast cancer-related lymphedema (BCRL) is a common complication affecting the upper extremity following breast cancer treatment.
- Trial name
- NCT05934695
- Testing
- Lymphedema severity stratification
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ahram Canadian University
Scleroderma
Brain Boost Program to Improve Cognitive Function in People With Systemic Sclerosis
The purpose of this study is to examine whether an 8-week online educational group-based program tailored to people with systemic sclerosis can help improve cognitive function and well-being.
- Trial name
- NCT06880627
- Testing
- Brain Boost group, Waitlist group
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Michigan
Breast Cancer
Gonadotropin-Releasing Hormone Agonist for the Preservation of Ovarian Function During Chemotherapy in Premenopausal Breast Cancer
The study is a prospective randomized control clinical trial which is sponsored by the researchers. The purpose of this study is to determine the effectiveness of Gonadotropin-Releasing hormone agonist on ovarian function for…
- Trial name
- POF (NCT02483767)
- Testing
- goserelin, standard chemotherapy
- Volunteers
- 98 people
- Sponsor
- Peking Union Medical College Hospital
Rosacea
Rosacea and Ivermectin
The primary hypothesis is that weekly digital interactions and routine measurement of Transepidermal Water Loss (TEWL) rates and Subcutaneous hydration levels will promote patient adherence to maintenance ivermectin therapy and…
- Trial name
- NCT04275999
- Testing
- ivermectin, digital interaction, GPSkin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Wake Forest University Health Sciences
Breast Cancer, Cognitive Impairment
Relationships Among Cognitive Function, Lifestyle, and Exercise After Cancer Treatment
The purpose of this study is to examine relationships among lifestyle behaviors (i.e., physical activity, sleep), cognitive function (i.e., memory, processing speed, and executive function), and quality of life in breast cancer…
- Trial name
- ReFLECT (NCT02523677)
- Where
- United States
- Volunteers
- 456 people
- Sponsor
- University of Illinois at Urbana-Champaign
Locally Advanced Breast Cancer, Breast Cancer
Using Bio Markers to Predict Disease Recurrence and Cognitive Function in High Risk Breast Ca
Women with breast cancer undergo treatments that decrease the chance of recurrence of cancer, but are associated with several side effects, including declines in memory and attention and other thinking abilities.
- Trial name
- Cyto-Cog (NCT00756132)
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Psoriasis
Pythagorean Self-Awareness Intervention on Psoriasis Patients.
This one-arm, pilot, non-randomized, study was conducted at the Specialized Psoriasis Unit of Andreas Syggros Hospital in Athens, Greece.
- Trial name
- PSAIPSORIASI (NCT06691763)
- Testing
- Pythagorean Self-Awareness Intervention for stress management and health promotion
- Where
- Greece
- Volunteers
- 21 people
- Sponsor
- National and Kapodistrian University of Athens
Psoriatic Arthritis, Foot Arthritis
Effect of Custom Foot Orthoses in Patients With Psoriatic Arthritis
Foot involvement is a major concern in psoriatic arthritis (PsA). The patients could experience severe levels of foot pain and disability and reduced mobility and quality of life.
- Trial name
- NCT05075343
- Testing
- Custom foot orthoses
- Where
- 2 sites in Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Patrick Boissy
Atopic Eczema/Dermatitis (Non-Specific)
Skin bioMARkers for Atopic Eczema Therapy Evaluation
The study aims to investigate two new non-invasive technologies for assessing skin properties to identify and validate a range of safety biomarkers that may be considered useful as primary outcome measures for evaluating the…
- Trial name
- SMART (NCT04194814)
- Testing
- crisaborole (2%) ointment, betamethasone valerate 0.1% cream
- Where
- United Kingdom
- Volunteers
- 37 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Polycystic Ovary Syndrome
Metformin Treatment in Polycystic Ovary Syndrome (PCOS)
PCOS occurs when a woman does not release an egg regularly each month, causing her periods to be irregular. Women with PCOS can also have increased hair growth on the face and body, acne, head balding, infertility, pre-diabetes…
- Trial name
- NCT02198417
- Testing
- Metformin ER
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Gonadotropin Releasing Hormone Agonists, Ovarian Function
Gonadotropin-Releasing Hormone Agonists Benefit in Preserving the Ovarian Function in Premenopausal Breast Cancer Patients During Chemotherapy
The purpose of this study is to investigate the benefits of gonadotropin-releasing hormone agonist administration during chemotherapy on preserving ovarian function and Fertility in Premenopausal breast cancer patients, as…
- Conditions
- Gonadotropin Releasing Hormone Agonists, Ovarian Function, Premenopausal, Breast Cancer
- Trial name
- NCT07127315
- Testing
- Gonadotropin-releasing hormone agonist, Chemotherapy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Helwan University
Schizophrenia
A Neurobiological Study on Heterogeneity of Schizophrenia: Genetic Variations and Neurobiological Differentiations
Schizophrenia (SCH) is a devastating brain disorder with grave personal, family and social cost. SCH is a complex and heterogeneous (both genetic and clinical) disorder with oligogenetic endowed vulnerability risk of disease…
- Trial name
- SONPOS (NCT01075373)
- Where
- Taiwan
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Breast Cancer, Sarcoma
Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
This is a phase 2a, randomized, double-blinded, placebo-controlled pilot clinical trial determining the impact of riluzole therapy on circulating brain derived neuropathic factor (BDNF) levels in cancer survivors (recently…
- Conditions
- Breast Cancer, Sarcoma, Gastric Cancer, Lung Cancer
- Trial name
- NCT06580002
- Testing
- Riluzole
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of California, Irvine
Systemic Sclerosis (SSc), Hand Function
Hand ScleroDerma Lived Experience Scale in Individuals With Systemic Sclerosis
The aim of this study was to examine the Turkish validity and reliability of the Hand scleroDerma lived Experience Scale (HAnDE Scale) Questionnaire in individuals with SSc.
- Trial name
- NCT06658483
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Pamukkale University
Skin Physiology, Dermal Administration
Topical Application of Highly Concentrated Water-in-oil Emulsions
The purpose of this study is to I. determine the effect of repetitive application of newly developed silicone based formulations (placebo water-in-oil emulsions) on transepidermal water loss and other physiological skin…
- Conditions
- Skin Physiology, Dermal Administration, Emulsions
- Trial name
- NCT03876639
- Testing
- Application of emulsion, Measurement of physiological skin parameters, Tape stripping
- Where
- Austria
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Rheumatoid Arthritis
Meditation Effects on Brain Function in Rheumatoid Arthritis
The purpose of this study is to determine the neural mechanisms supporting meditation-based pain relief in rheumatoid arthritis (RA) patients.
- Trial name
- NCT03975595
- Testing
- Meditation Intervention A, Meditation Intervention B
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Johns Hopkins University
Rheumatoid Arthritis, Stiffness, Aortic
Methotrexate, Blood Pressure and Arterial Function in Rheumatoid Arthritis
The investigators will study the effects of methotrexate on blood pressure, arterial stiffness and endothelial function in patients with rheumatoid arthritis.
- Conditions
- Rheumatoid Arthritis, Stiffness, Aortic, Endothelial Dysfunction, Cardiovascular Risk Factor
- Trial name
- NCT03254589
- Testing
- Methotrexate, Sulfasalazine, Other DMARDs
- Where
- Australia
- Volunteers
- 124 people
- Sponsor
- Flinders University
Systemic Lupus Erythematosus (SLE), Visual Function
Study on Early Visual Dysfunction in Patients With Systemic Lupus Erythematosus
OCT, OCTA, fundus photography, and fundus autofluorescence ( FAF ) were used to observe the fundus physiological indexes of normal subjects and SLE patients, to explore the differences of subclinical retinal damage in SLE…
- Trial name
- NCT07679776
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Osteoarthritis, Avascular Necrosis
Post-PMA Approval Study: 10 Year Follow-Up IDE Subjects
primary endpoint of this Study is maintenance of "at least good clinical status" for a period of 10 years following initial implantation among Cormet procedures enrolled inthe pre-market IDE.
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis
- Trial name
- PAS:IDE (NCT00721994)
- Testing
- Cormet Hip Resurfacing System
- Where
- 5 sites in United States
- Volunteers
- 231 people
- Sponsor
- Corin