Clinical trials: Skin Physiology
Gonadotropin Releasing Hormone Agonists, Ovarian Function
Gonadotropin-Releasing Hormone Agonists Benefit in Preserving the Ovarian Function in Premenopausal Breast Cancer Patients During Chemotherapy
The purpose of this study is to investigate the benefits of gonadotropin-releasing hormone agonist administration during chemotherapy on preserving ovarian function and Fertility in Premenopausal breast cancer patients, as…
- Conditions
- Gonadotropin Releasing Hormone Agonists, Ovarian Function, Premenopausal, Breast Cancer
- Trial name
- NCT07127315
- Testing
- Gonadotropin-releasing hormone agonist, Chemotherapy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Helwan University
Diabetic Neuropathy
NIR- and Multifrequent Impedance Spectroscopy on the Skin in Type 1 Diabetes
The aim of the study is to examine the suitability to detect diabetic neuropathy using NIR and impedance.
- Trial name
- NIR (NCT01707979)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lise Tarnow
Rheumatoid Arthritis, Healthy Control
Core Endurance, Finger Grip Strength, Fatigue, and Hand Function in Patients With Rheumatoid Arthritis
This study investigated the relationships between core endurance, finger grip strength, fatigue, and hand function in patients with rheumatoid arthritis.
- Trial name
- NCT07360496
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Breast Cancer
All-extremity Exercise During Breast Cancer Chemotherapy
Currently, there are 3.5 million breast cancer survivors in the United States and this number is expected to increase dramatically.
- Trial name
- NCT04914663
- Testing
- Exercise training
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Florida
Non Small Cell Lung Cancer, Advanced Solid Tumor
Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC
This is a First-in-Human Phase IA/IB/II open label dose escalation study of intravenous (IV) administration of ONC-392, a humanized anti-CTLA4 IgG1 monoclonal antibody, as single agent and in combination with pembrolizumab in…
- Conditions
- Non Small Cell Lung Cancer, Advanced Solid Tumor, Metastatic Melanoma, Metastatic Head and Neck Carcinoma
- Trial name
- PRESERVE-001 (NCT04140526)
- Testing
- ONC-392, Pembrolizumab, Docetaxel
- Where
- 37 sites in United States, Australia
- Volunteers
- 733 people
- Sponsor
- OncoC4, Inc.
Breast Cancer, Lymphedema
Morbidity Following the Diagnosis and Treatment of Patients With Breast Cancer
This study will examine the frequency and severity of problems in women with breast cancer during the first year after initial medical treatment, including: Physical impairments, such as loss of strength or flexibility, increased…
- Conditions
- Breast Cancer, Lymphedema, Physical Therapy, Shoulder
- Trial name
- NCT00027105
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Skin Physiology, Dermal Administration
Topical Application of Highly Concentrated Water-in-oil Emulsions
The purpose of this study is to I. determine the effect of repetitive application of newly developed silicone based formulations (placebo water-in-oil emulsions) on transepidermal water loss and other physiological skin…
- Conditions
- Skin Physiology, Dermal Administration, Emulsions
- Trial name
- NCT03876639
- Testing
- Application of emulsion, Measurement of physiological skin parameters, Tape stripping
- Where
- Austria
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Skin Barrier Function, Skin Soothing Effect
Mask Instant Clinical Study
The goal of this clinical study is to evaluate the soothing effect of the test product within 2 hours after a single application by measuring changes in multiple indicators before and after product use.
- Trial name
- NCT07896993
- Testing
- Test soothing facial mask
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Interstitial Lung Disease (ILD), Connective Tissue Disease-associated Interstitial Lung Disease
A Study to Test Tetrandrine Tablets for Connective Tissue Disease-Related Lung Disease
This study evaluates the efficacy and safety of tetrandrine tablets (60 mg, three times daily) compared to placebo in adult patients with connective tissue disease-related interstitial lung disease.
- Trial name
- NCT07319598
- Testing
- Tetrandrine Tablets
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Pulmonary Healthy Controls, Interstitial Lung Disease
Evaluation of Novel Lung Function Parameters in Patients With Interstitial Lung Disease (ILD)
Current diagnostic tools used in interstitial lung disease (ILD) do not meet the challenges set by the complex pathophysiology of this heterogenous group.
- Conditions
- Pulmonary Healthy Controls, Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis, Non-specific Interstitial Pneumonia
- Trial name
- NCT02827734
- Testing
- multiple breath washout tests, impulse oscillometry, body plethysmography
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Breast Cancer, Chemotherapy Effect
Improving Cognitive Function Through High-intensity Interval Training in Breast Cancer Patients Undergoing Chemotherapy
The purpose of this research is to determine whether a 16-week high intensity interval training (HIIT) exercise program will improve brain health among women undergoing chemotherapy and also improve cardiovascular (heart)…
- Conditions
- Breast Cancer, Chemotherapy Effect, Exercise Therapy, Cognitive Change
- Trial name
- CLARITY (NCT04724499)
- Testing
- High-Intensity Intervals Training, Attention Control
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dana-Farber Cancer Institute
Rheumatoid Arthritis
Effects of Underwater Ultrasound Therapy on Hand Function and Quality of Life in Patients With Rheumatoid Arthritis
In this randomized, double-blind, placebo-controlled study the effects of underwater ultrasound (US) therapy were investigated in 48 patients with moderately active rheumatoid arthritis (disease activity score in 28 joints…
- Trial name
- NCT02706028
- Testing
- underwater ultrasound
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- Petz Aladar County Teaching Hospital
Arthritis, Osteoarthritis
Program Evaluation of People With Arthritis Can Exercise
The purpose of this study is to evaluate the health and arthritis-specific benefits of participation in the Arthritis Foundation People with Arthritis Can Exercise program and to collect information to improve community-based…
- Conditions
- Arthritis, Osteoarthritis, Rheumatoid Arthritis
- Trial name
- NCT00153309
- Testing
- People with Arthritis Can Exercise
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- Centers for Disease Control and Prevention
Diabetic Neuropathies
Effect of Customized Software for Foot-related Exercises (SOPeD) for Prevention and Treatment in People With Diabetic Neuropathy
The main objective of this trial is to investigate the effect of a customized foot-related exercises software (SOPeD) in diabetic neuropathy status, functional outcomes and gait biomechanics in people with diabetic neuropathy.
- Trial name
- FOCA-I (NCT04011267)
- Testing
- Physical therapy by foot-ankle segmental and functional exercises
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- University of Sao Paulo General Hospital
Gastrointestinal Cancer, Head and Neck Cancer
Microvascular Function in Patients Undergoing 5-Fluorouracil Chemotherapy
The primary aim of this study is to investigate potential differences in vascular function between patients receiving 5-Fluorouracil (5-FU) chemotherapy, patients receiving chemotherapies other than 5-FU, cancer survivors who…
- Conditions
- Gastrointestinal Cancer, Head and Neck Cancer, Breast Cancer, Chemotherapy Effect
- Trial name
- NCT04042298
- Testing
- Arterial blood pressure, Skin microcirculatory blood flow, Brachial artery blood flow
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Atopic Dermatitis (AD)
Effect of Partially Hydrolyzed Formula With Synbiotics on Skin Barrier Function
The main purpose of this study is to assess the efficacy of a partially hydrolyzed formula with synbiotics in halting one of the first steps of the allergic march (atopic dermatitis) in infants at risk of allergy.
- Trial name
- SPHINX (NCT06943469)
- Testing
- Test formula, Control formula
- Where
- 25 sites in Belgium, France and 3 more
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Rheumatoid Arthritis
Long-Term Assessment of Safety and Physical Function With AMG 108 in RA
The purpose of this study is to assess long-term safety of SC AMG 108 in the treatment of RA
- Trial name
- NCT00369473
- Testing
- AMG 108
- Volunteers
- 690 people
- Sponsor
- Amgen
Psoriatic Arthritis
Comparison of Hand Functions and Wrist Proprioception in Patients With and Without Psoriatic Arthritis
The purpose of this study is to assess hand functions and wrist joint position sense in patients with and without PsA.
- Trial name
- NCT04553302
- Testing
- This study does not contain any intervention.
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Melissa Köprülüoğlu
Age Related Macular Degeneration, Cognition Disorders
The Zeaxanthin and Visual Function Study
To evaluate if supplementation of zeaxanthin (with or without Lutein) is beneficial to patients with early and moderate Atrophic Age Related Macular Degeneration.
- Trial name
- ZVF (NCT00564902)
- Testing
- 3R 3'R Zeaxanthin, Lutein, Lutein and Zeaxanthin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Chrysantis, Inc.
Rheumatoid Arthritis
STudying Ageing in Rheumatic Diseases (STAR)
The primary objective of the STAR study is to investigate how measures of disease activity and measures for cognition, physical activity and performance behave in ageing population controls and patients with rheumatoid arthritis…
- Trial name
- NCT05463666
- Testing
- Rheumatoid arthritis
- Where
- Netherlands
- Volunteers
- 840 people
- Sponsor
- Maastricht University Medical Center