Clinical trials: Skin Pigmentation
Pancreatic Neoplasm, Peutz-Jeghers Syndrome
Cancer of the Pancreas Screening Study (CAPS 3)
The purpose of this study is to find the best and most sensitive screening modality (CT, MRI, EUS)for very small pre-cancerous pancreatic lesions and to treat these small lesions before they turn into cancer.
- Trial name
- CAPS 3 (NCT00438906)
- Testing
- Biopsy, Fine Needle Aspiration (FNA), Secretin (human synthetic) - ChiRhoClin
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Melasma
Effectiveness and Safety of Intradermal Tranexamic Acid Injection as An Adjunctive Treatment for Melasma in Skin Type IV - V
A double-blind, randomized, split-face controlled trial of 34 female patients with melasma was conducted. All subject were randomized to receive either intradermal tranexamic acid or placebo injection on the right or the left…
- Trial name
- NCT05236569
- Testing
- Tranexamic acid injection, Injection Water
- Where
- Indonesia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Picoseconds Laser, Melasma
A Comparative Study for Efficacy and Safety Between 4% Hydroquinone Cream With or Without Fractional Picosecond 1,064 nm Laser for the Treatment of Dermal or Mixed Type Melasma
A Comparative study for Efficacy and Safety Between 4% hydroquinone cream with or without Fractional Picosecond 1,064 nm Laser for the Treatment of Dermal or Mixed Type Melasma
- Trial name
- NCT03049059
- Testing
- Fractional Picosecond 1,064 nm laser, 4% hydroquinone cream
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mae Fah Luang University Hospital
Pressure Injuries, Pressure Ulcers, Bedsores, Decubitus Ulcer
Prevention of Pressure Injury (PI) in Hospitalised Infants, Children, and Young People (CYP) (Aged 0-19 Years)
What is the problem? Children and young people admitted to hospital can sometimes be harmed by what is called a pressure injury. Pressure injuries are sores (ulcers) that happen on areas of the skin that are under pressure.
- Trial name
- CYPPI (NCT07303569)
- Where
- United Kingdom
- Volunteers
- 542 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Pigmentation
Evaluation of the Efficacy and Safety of PiQo4 System for the Treatment of Pigmented Lesions
A total of at least 25 healthy subjects at a single site, aged 21-70 years old with congenital or acquired challenging/resistant, age/sun-related flat and benign facial pigmentation with or without hand pigmentation who wish to…
- Trial name
- NCT03565146
- Testing
- PiQo4 Laser System
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Focus Medical, LLC
Wrinkle, Skin Pigmentation
Prospective Study of Topical Vitamin C (THDA) Versus Topical Vitamin C (THDA) With Acetyl Zingerone
The purpose of this study is to asses the impact of topically applying a form of vitamin C known as tetrahexyldecyl Ascorbate (THDA) along with a novel anti-aging ingredient, acetyl zingerone, compared against applying THDA alone.
- Trial name
- NCT05779280
- Testing
- THDA + Acetyl Zingerone Topical Product, THDA
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Vitiligo
Role of NGAL in Vitiligo
Role of serum Neutrophil Gelatinase-associated Lipocalin in early detection of cardiovascular risk in patients with Vitiligo
- Trial name
- NCT05290077
- Testing
- NGAL
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Lentigo
The Effect of Topical Anesthetics on Patients' Pain and Operative Experience During Treatment With QSwitched Laser
This study will conduct a split-face and -body randomized control trial to compare lidocaine 2.5%/prilocaine 2.5% topical anesthetic (LPTA), lidocaine 7%/tetracaine 7% topical anesthetic (LTTA), and placebo vechicle (PV) on…
- Trial name
- NCT02427724
- Testing
- lidocaine 2.5%/prilocaine 2.5% topical anesthetic, lidocaine 7%/tetracaine 7% topical anesthetic, Q-switched 532nm Laser
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Lentigines
A Single-Center 2-Arm Study for Lentigines on the Hands
The purpose of this study is to evaluate the effectiveness and safety of two laser systems for improvement of lentigines on the hands.
- Trial name
- NCT02763072
- Testing
- Enlighten Laser, Excel V Laser
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Skin Pigmentation, Healthy Volunteers
Efficacy of Cosmetic Products in Preventing Pigmentation Induced by High Energy Visible Light (HEVL) [400-450nm]
The goal of this double-blind, randomized clinical trial is to evaluate the efficacy of anti-pigmentation cosmetic products in preventing skin pigmentation induced by High Energy Visible Light (HEVL) [400-450nm] in healthy…
- Conditions
- Skin Pigmentation, Healthy Volunteers, Hyperpigmentation
- Trial name
- NCT07537595
- Testing
- Treated and exposed zones (cosmetic topical products applied), Untreated and exposed zone (no product applied)
- Where
- Romania
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Fruit and Vegetable Consumption
You Are What You Eat: A Randomised Controlled Trial of an Appearance-based Dietary Intervention
This study investigated whether illustration of the facial appearance benefits of fruit and vegetable consumption is able to motivate increased intake of this food group.
- Trial name
- NCT01511484
- Testing
- Information-only, Generic appearance intervention, Personalised appearance intervention
- Where
- United Kingdom
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Perception Lab
Visible Light Exposure on Healthy Back Skin
MELASYL EFFICACY UNDER PART OF VISIBLE LIGHT
The study intends to evaluate the efficacy of an anti-melanogenesis active in different concentrations under part of visible Light [400-450nm] exposures and under full visible light [400-700nm] exposures.
- Trial name
- BIOVI2 (NCT06937515)
- Testing
- Cosmetic topical products
- Where
- Romania
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Photoaging
Combination Versus Laser Treatment Only
Our objective is to determine the effects of (1) basic skin care regimen + "active" (Lytera 2.0) vs. (2) basic skin care regimen only, both groups combined with laser, on the appearance of skin tone and photo-aging on the face.
- Trial name
- NCT03661697
- Testing
- Laser Therapy, Basic Skin Care Regimen, Lytera
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Miami
Melasma
Efficacy and Safety of Using Combination of 755-nm Picosecond Alexandrite Laser and 2% Hydroquinone Compared With 2% Hydroquinone Alone for the Treatment of Melasma: a Randomized Split-face Controlled Trial
This study aims to assess the efficacy and safety of using combination of 755-nm picosecond alexandrite laser and 2% hydroquinone compared with 2% hydroquinone alone for the treatment of melasma: A randomized split-face…
- Trial name
- NCT04597203
- Testing
- 755-nm picosecond alexandrite laser with topical 2% hydroquinone, topical 2% hydroquinone
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mahidol University
POH
Evaluation of the Effectiveness of the PiQo4 System for Reduction of Infra-orbital Pigmentation
A total of 10 healthy subjects at a single site, aged 18-65 years old and Fitzpatrick skin type I-IV with mild to moderate infra-orbital hyperpigmentation on the background of epidermal and/or dermal pigmentation that wish to…
- Trial name
- NCT04214873
- Testing
- PiQo4 Laser System
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Focus Medical, LLC
Wrinkle, Pigmentation
Device for Improving Skin Quality and Texture on the Face and Neck
The goal of this clinical trial is to investigate the effect of the BTL-785F device (with BTL-785-4-4 tip on BTL-785-4 applicator) on the improvement of skin quality and texture on the face and neck in healthy adult volunteers.
- Conditions
- Wrinkle, Pigmentation, Skin Laxity, Skin Scarring
- Trial name
- NCT06645366
- Testing
- Treatment with BTL-785F
- Where
- 3 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Hyperpigmentation, Pediatric Dermatology
A Study on Pigmentation Disorders in Children
The descriptive cross-sectional study was undertaken at Kanti Children's Hospital during the period from January 2020 to June 2021.
- Trial name
- NCT06189768
- Where
- Nepal
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Nepal Health Research Council
Photodamage
Laser 360iQ: Optimal Light-laser Combination Therapy
To assess the safety and efficacy of light-laser combination therapy for the improvement of skin color, tone, texture and laxity
- Trial name
- NCT04519723
- Testing
- Assess the safety and efficacy of light-laser therapy using the Harmony XL and Dye-VL (500-600nm), Q-Switched 1064nm, Er:YAG 2940nm modules in combination .
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Alma Lasers Inc.
Vitiligo, Healthy
The Gut and Skin Microbiome in Vitiligo Disease Progression
Investigators plan to perform a pilot study that aims to characterize the microbiome of human vitiligo patients with both active and stable disease and compare this to the microbiome of age and sex matched controls.
- Trial name
- NCT03577327
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Urticaria Pigmentosa, Cutaneous Mastocytosis
Cutaneous Mastocytosis in Children: Analysis of Somatic and Germline Mutations
Pediatric mastocytosis is an orphan disease, which encompasses several clinically distinct entities including solitary mastocytoma, urticaria pigmentosa, diffuse cutaneous mastocytosis and the newly recognized mast cell…
- Trial name
- NCT02761473
- Testing
- skin biopsy, blood draw
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Minnesota