Clinical trials: Skin Pigmentation
Healthy
Pigment-Tan-Safety Study of a Light-based Home Device for Hair Removal in Adult Subjects
This studies was designed to investigate the importance of skin type and UV-exposure on side effects after exposure to an Intense Pulsed Light Home-use device.
- Trial name
- NCT01763723
- Testing
- IPL-home use device
- Where
- Denmark
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Pigmentation, Oxidative Stress
A Study to Evaluate the Ability of Sunscreen Products to Modulate the Effects of Deep UVA +/- HEV Blue Light Induced Pigmentation and Biomarkers of Cutaneous Oxidative Stress
To assess the level of sub pigmentation following an acute exposure to a Deep Ultraviolet A and high energy Blue Light wavelengths (380-420 nm).
- Trial name
- NCT07695753
- Testing
- Sunscreen application #1, Sunscreen application #2
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Kenvue Brands LLC
Pigmentation, Gingiva
Post Gingival Depigmentation Assessment: Comparison of Surgical Stripping vs (Er,Cr:YSGG) Laser
The appearance and health of the gingiva significantly contribute to an aesthetically pleasing smile. Pink gingiva indicates healthy gums and is generally preferred over dark or mixed colors.
- Trial name
- NCT06075641
- Testing
- Gingival depigmentation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Visible Light Exposure on Healthy Back Skin
Agents Effect Under Visible Light on Caucasian, Asian and Darker Skin Types
The study intends to get knowledge on pigmentation induced by visible light on Asian/Chinese skin type and darker skin type, and to evaluate and to compare with a non-treated control zone and between them, the efficacy of…
- Trial name
- VLAD (NCT07462845)
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Melasma
Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes in the Treatment of Melasma
Melasma is a refractory skin disease with a complex pathogenesis and difficult treatment. Research has found that mesenchymal stem cell-derived exosomes have effects such as anti-wrinkle formation, anti-inflammation, antioxidant…
- Trial name
- NCT06677931
- Testing
- 1565 non-ablative fractional laser combined with umbilical cord mesenchymal stem cell-derived exosomes.
- Where
- 2 sites in China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Vitiligo
The Investigation on the Expression of High Mobility Group Protein Box-1 (HMGB1) in Peripheral Blood of Vitiligo Patients and Healthy Controls According to Clinical Features, Treatment and Disease Activity
Vitiligo is an acquired depigmented disorder that causes white spots on the skin due to the loss of melanocytes. It is a common disease which accounts for 0.5-1% of the whole population.
- Trial name
- NCT03741738
- Where
- South Korea
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Vitiligo
Assessment of Hypoxia Inducible Factor and Autophagy Related Genes in Patients With Non-Segmental Vitiligo
The present study will aim to evaluate: 1. The presence of Hypoxia Inducible Factor in vitiligo patient 2. Defect of Autophagy Related Genes in vitiligo patient 3.
- Trial name
- NCT06410898
- Testing
- Punch Biopsy 5mm
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sohag University
Vitiligo
Evaluation of Serum and Tissue Cathepsin L in Non-segmental Vitiligo Patients
Introduction Vitiligo is an autoimmune disease of the skin that targets pigment producing melanocytes and results in patches of depigmentation that are visible as white spots (Frisoli et al., 2020) Vitiligo is a relatively common…
- Trial name
- NCT06261073
- Testing
- blood sample and tissue biopsy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sohag University
Melasma
Efficacy of Radiofrequency Micro Needling for the Treatment of Melasma in Skin of Color.
The objective of this study is to test the effectiveness of radiofrequency microneedling (RFMN) as a treatment for melasma. The Investigator hypothesize that RFMN will be an effective treatment for melasma in skin of color…
- Trial name
- SylfirmX (NCT06616311)
- Testing
- Radiofrequency microneedling
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Tattoo; Pigmentation
Evaluating the Safety and Performance Characteristics of Ephemeral® Tattoo Ink in Healthy Subjects
An Open-Label, Single-Center, Prospective, Observational, Clinical Use Study Evaluating the Safety and Performance Characteristics of Ephemeral® Tattoo Ink in Healthy Subjects
- Trial name
- NCT05877833
- Testing
- Vibrancy Assessment
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ephemeral Solutions Inc.
Skin Pigmentation
Evaluation of a Tranexamoc Acid Treatment on Post-inflammatory Pigmentation in the Suction Blister Model
Post-inflammatory hyperpigmentation (PIH) is a common sequela of inflammatory dermatoses. PIH results from the overproduction of melanin or irregular pigment dispersion after skin inflammation.
- Trial name
- TRANEX (NCT05311033)
- Testing
- Exacyl
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Melasma
Cysteamine Compared to Hydroquinone in Melasma
Melasma is an acquired pigmentary disorder of symmetrical hyperpigmentation appearing as variable darkness macules and patches over the forehead, cheeks, and chin, even sun-exposed areas of the body.
- Trial name
- NCT05969587
- Testing
- 5% cysteamine cream, hydroquinone cream group
- Where
- Taiwan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Pigment; Lesion, Lesion; Vascular
Image Data Collection of Tanned Skin During Phototherapy Treatment Using a Multi-spectral Camera
This is a prospective, observational, single-center, image collection study. Any patient who arrived at the phototherapy clinic for the first time, regardless of this study, and is prescribed a total of 30 treatments can be…
- Trial name
- NCT05692544
- Testing
- Phototherapy treatment
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Acne, Acne Scars - Mixed Atrophic and Hypertrophic
AVAVA MIRIA General Use
A general protocol to treat a variety of dermatologic conditions and collect patient feedback. Primary outcome is the collection and analysis of patient questionnaires related to the overall experience of the device treatment.
- Conditions
- Acne, Acne Scars - Mixed Atrophic and Hypertrophic, Scars, Wrinkle
- Trial name
- NCT06868615
- Testing
- AVAVA
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- AVAVA, Inc.
Vitiligo Vulgaris
Online Health Survey of Patients With Vitiligo Vulgaris/ Online Survey of Pediatric Patients With Vitiligo
The study is an on-line survey posted on survey monkey that addresses some demographic and environmental issues that could potentially relate to vitiligo vulgaris onset or disease exacerbation.
- Trial name
- NCT01401374
- Where
- United States
- Volunteers
- 3,258 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Melasma
Oral Polypodium Leucotomos for Melasma
Primary Objective: To determine whether there is improvement in the melasma of participants taking oral Polypodium Leucotomos Secondary Objective: To determine whether oral Polypodium Leucotomos is well tolerated in study…
- Trial name
- NCT01162850
- Testing
- Polypodium Leucotomos
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Miami
Hyperpigmentation
Efficacy and Tolerability of Tested Formula After 3 Months of Treatment of Facial Hyperpigmentation of 3 Origins
The objective of this study is to evaluate the efficacy, cosmetic acceptability and improvement of the stigmatization of the tested product (2039125 03) used bis in die (BID) for 3 months in adult patients suffering from mild to…
- Trial name
- NCT06253468
- Testing
- tested product
- Where
- Singapore
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Vitiligo
PHNA, Efficacy of Tretinoin Cream on Post-phototherapy Hyperpigmentation
A randomized controlled split-face pilot study was planned to investigate the preventive effect of tretinoin 0.05% cream on hyperpigmentation during phototherapy in patients with vitiligo.
- Trial name
- NCT03933774
- Testing
- Tretinoin 0.05% cream
- Where
- South Korea
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Muscle Oxygenation, Skin Pigmentation
Muscle Oxygenation and Skin Pigmentation
The investigators plan to enroll 500 consecutive Subjects at a major trauma center for this study. For each patient, the body mass index (BMI), age, sex, diastolic pressure and mean arterial pressure (MAP) at time of…
- Trial name
- NCT00747162
- Testing
- Measure of muscle oxygenation, Skin pigmentation determination
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Emory University
Healthy
Effect of Skin Pigmentation and Race/Ethnicity Factors on the Accuracy of Masimo Pulse Oximeters
This study is designed to compare the accuracy of a noninvasive measurement of oxygen saturation compared to reference values obtained by a laboratory blood gas analyzer.
- Trial name
- NCT04889222
- Testing
- INVSENSOR00050, RD SET SpO2
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation