Clinical trials: Skin Resurfacing
Skin Cancer
Post Excision/Mohs Scar Laser Resurfacing
The purpose of this study is to evaluate the potential benefits of treating a surgical scar post excision with an ablative fractionated CO2 laser with the goal of decreasing the appearance and size of the scar.
- Trial name
- NCT02130297
- Testing
- Laser Treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Rheumatoid Arthritis
Transplantation of Bone Marrow Derived Mesenchymal Stem Cells in Affected Knee Osteoarthritis by Rheumatoid Arthritis
Osteoarthritis of the knee is one of the most common causes of disability among elderly. Arthritis rheumatoid is an autoimmune disease which causes multi articular arthritis, such as knee osteoarthritis.
- Trial name
- NCT01873625
- Testing
- mesenchymal cell transplantation
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Royan Institute
Avascular Necrosis of Hip, Osteoarthritis, Hip
Metasul Monoblock Component™ Cup in a Hip Resurfacing Application With the Durom® Hip Resurfacing Femoral Component
The Zimmer Hip Resurfacing System Post-Market Clinical Follow-up study will examine the safety and efficacy of this device in the young and/or active patient with advanced hip disease.
- Conditions
- Avascular Necrosis of Hip, Osteoarthritis, Hip, Rheumatoid Arthritis, Inflammatory Arthritis
- Trial name
- MMC (NCT03681639)
- Testing
- Serum Metal ion levels determined to monitor changes in chromium and cobalt levels
- Where
- Germany
- Volunteers
- 45 people
- Sponsor
- Zimmer Biomet
Stable Vitiligo
Efficiency of Fractional-Laser Resurfacing Followed by Topical Tacrolimus 0.03% Cream vs Tacrolimus Alone in Vitiligo
The aim the clinical trial was to find out whether fractional CO₂ laser sessions in combination with application of daily topical tacrolimus 0.03% would enhance the action of the drug and pose as a possible combination treatment…
- Trial name
- NCT03535051
- Testing
- fractional carbon dioxide laser, Tacrolimus Oint 0.03%
- Volunteers
- 27 people
- Sponsor
- Kasr El Aini Hospital
Skin Graft Disorder, Disorder of Skin Donor Site
Wound-healing Improvement by Resurfacing Split-Thickness Skin Donor Sites With Thin Split-thickness Grafting
Split-thickness skin grafting remains fundamental treatment of patients with deep burns and other traumatic injuries. However, the split-thickness skin graft (STSG) donor site dressing has been controversial until now.
- Conditions
- Skin Graft Disorder, Disorder of Skin Donor Site, Wound Healing Disturbance of
- Trial name
- NCT01974583
- Testing
- regrafted with thin split-thickness skin graft, covered with the occlusive hydrocellular dressing, covered with paraffin gauze
- Volunteers
- 192 people
- Sponsor
- Tang-Du Hospital
Skin Quality Improvement, Photo-aged Skin
Fractional CO2 Laser-assisted Delivery of Hyaluronic Acid, Ascorbic Acid and Sodium DNA For Enhancing Facial Skin Quality in Individuals Over the Age of 30
Evaluate the effectiveness of topical hyaluronic acid, ascorbic acid, and sodium DNA following ablative fractional laser treatment in objectively reversing facial skin alterations induced by photoaging.
- Conditions
- Skin Quality Improvement, Photo-aged Skin, Drug Delivery Systems
- Trial name
- FCLADHAAASDFSQ (NCT07376148)
- Testing
- topical hyaluronic acid, ascorbic acid, and sodium DNA following ablative fractional laser treatment
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Wounds
Efficacy Study of GLYC-101 to Evaluate Outcomes After Post-laser Ablation
Study is intended to evaluate safety and efficacy parameters in patients treated with GLYC-101 gel or placebo after laser ablation.
- Trial name
- NCT00656474
- Testing
- GLYC-101 gel (1.0 %)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- TR Therapeutics
Rheumatoid Arthritis, Osteoarthritis
A Multi-centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery
The purpose of this study is to monitor the performance and determine the metal ion release of the DePuy ASR™ System in the treatment of patients with hip joint disease requiring hip resurfacing surgery.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders
- Trial name
- NCT00208377
- Testing
- DePuy ASR Hip System
- Where
- 3 sites in Australia, Germany and 1 more
- Volunteers
- 228 people
- Sponsor
- DePuy International
Acquired Absence of Lower Limb, Scar Condition and Fibrosis of the Skin
LASER Pilot Project
Veterans who use prosthetic limbs commonly suffer from skin problems such as scars that create discomfort and pain to the point that wearing the prosthesis is no longer tolerable.
- Trial name
- LASER (NCT05966636)
- Testing
- Fractional CO2 Laser Ablative Resurfacing
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Melasma, Acne Scars - Mixed Atrophic and Hypertrophic
Comparative Effects Of Trichloroacetic Chemical Peel And Fractional Laser
More than aesthetics, the search for orofacial harmonization treatments has increased when the negative emotional impact of some facial conditions such as melasma and acne scars is recognized.
- Conditions
- Melasma, Acne Scars - Mixed Atrophic and Hypertrophic, Resurfacing, Rejuvenation
- Trial name
- NCT07036302
- Testing
- 35% TCA combined with croton oil peel, Isolate 35% TCA peel, Erbium-YAG laser
- Where
- 2 sites in Brazil
- Volunteers
- 120 people
- Sponsor
- Jose Roberto Cortelli
Melasma
Oral Tranexamic Acid and Laser for Treatment of Melasma
Tranexamic acid and 1927 diode laser non-ablative fractionated laser for the treatment of Melasma.
- Trial name
- NCT03686787
- Testing
- Tranexamic Acid
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Laser and Skin Surgery Center of New York
Pain
S-Caine™ Peel (Skin Numbing Cream) to Treat Pain During Non-Ablative Facial Laser Resurfacing in Adults
Lasers are used for non-ablative resurfacing of facial rhytides, atrophic scars, and a variety of epidermal and dermal lesions. Pain associated with the non-ablative laser treatment has been described as moderate to severe.
- Trial name
- NCT00110747
- Testing
- S-Caine™ Peel (lidocaine and tetracaine topical cream 7%/7%)
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- ZARS Pharma Inc.
Facial Photo Damage, Periocular Fine Wrinkles
A Trial of Skin Care Protocols for Facial Resurfacing
The aims of the Skin Product Assessment Research study were to (1) develop an infrastructure and process for industry-sponsored, Plastic Surgery Educational Foundation (PSEF) research in facial aesthetic surgery and (2) test the…
- Conditions
- Facial Photo Damage, Periocular Fine Wrinkles, Perioral Fine Wrinkles
- Trial name
- SPAR (NCT01113606)
- Testing
- Obagi New-Derm System, Standard of Care
- Where
- 9 sites in United States
- Sponsor
- The Plastic Surgery Foundation
Face Rejuvenation, Neck Rejuvenation
Laser Treatment for Facial and Neck Rejuvenation
To assess the efficacy, safety, and patient satisfaction associated with the treatment of the face and neck with the 2,910nm mid-infrared UltraClear Laser System using both superficial epidermal ablation and deep ablative and…
- Trial name
- NCT05808842
- Testing
- CeraVe, CeraVe and Calecim
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Wounds
Efficacy Study of GLYC-101 to Evaluate Outcomes After Laser Ablation
The primary objectives of this study are to evaluate safety and efficacy of topically applied Glucoprime gel (GLYC-101, 0.1% and GLYC-101, 1.0%) in promoting wound healing in cosmetic surgery patients undergoing Carbon Dioxide…
- Trial name
- NCT00792688
- Testing
- GLYC-101 Gel (0.1%), GLYC-101 Gel (1.0%)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- TR Therapeutics
Osteoarthritis, Avascular Necrosis
Post-PMA Approval Study: 10 Year Follow-Up IDE Subjects
primary endpoint of this Study is maintenance of "at least good clinical status" for a period of 10 years following initial implantation among Cormet procedures enrolled inthe pre-market IDE.
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis
- Trial name
- PAS:IDE (NCT00721994)
- Testing
- Cormet Hip Resurfacing System
- Where
- 5 sites in United States
- Volunteers
- 231 people
- Sponsor
- Corin
Chemical Peeling
An Assessment of the Efficacy and Safety of Employing a Duosomal Chemical Peel for Aesthetic Enhancement in the Periocular and Facial Regions
This study will employ an experimental, prospective, longitudinal, and comparative before-and-after design. The objective is to assess the efficacy and safety of duosomal chemical peels as agents for enhancing the aesthetic…
- Trial name
- AESEDCPAEPFR (NCT07401342)
- Testing
- Duosomal chemical peel application
- Where
- Mexico
- Volunteers
- 12 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Pain
Comparison Study on Topical Anesthetic Agents (LMX4 and BLT) Prior to Fractional Skin Resurfacing
The purpose of this research study is to test which topical anesthesia: LMX4 (Lidocaine 4%) or BLT (Benzocaine 20%, Lidocaine 6%, and Tetracaine 4%) is more effective in reducing discomfort during treatment with the Fraxel DUAL…
- Trial name
- NCT01842373
- Testing
- LMX4, BLT
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Skin Texture Irregularities, Facial Skin Wrinkles
Safety & Efficacy Evaluation of a Radiofrequency & Laser/Light System for Improvement of Skin Texture
Evaluate the clinical performance, safety and efficacy, of a Radiofrequency and Laser/Light based device for the treatment of facial wrinkles.
- Trial name
- NCT01597323
- Where
- 3 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Skin Aging
Reduction in Symptoms After Laser Therapy With Acorn aHFS
This study evaluates the severity and duration of symptoms experienced after laser therapy comparing four post-procedure topical products.
- Trial name
- NCT06336135
- Testing
- autologous hair follicle derived secretome
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Acorn Biolabs Inc.