Clinical trials: Skin Resurfacing
Actinic Keratoses, Aging
Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia
This study is following up on previous studies that have demonstrated that geriatric subjects respond different to ultraviolet B (UVB) light than young subjects.
- Conditions
- Actinic Keratoses, Aging, Non-Melanoma Skin Cancer
- Trial name
- NCT03906253
- Testing
- Fractionated Laser Resurfacing
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Wright State University
Acne, Scar
Fractional Resurfacing Device for Treatment of Acne Scarring
The purpose of this research study is to evaluate the safety and effectiveness of a new investigational laser device for treatment of acne scarring, for improvement in the appearance of surface texture and topography (recessed or…
- Trial name
- NCT00585286
- Testing
- 10,600 nm fractional carbon dioxide laser system
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, Irvine
Osteoarthritis, Rheumatoid Arthritis
A Clinical Investigation of Recovery Following Hip Resurfacing or Total Hip Arthroplasty
The primary purpose of this study is to compare early functional outcomes in patients undergoing hip resurfacing and total hip arthroplasty with the M2a-Magnum™ using more objective measures of function.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Arthritis, Traumatic Arthritis
- Trial name
- NCT00585988
- Testing
- Hip Resurfacing System, M2a-Magnum™ Large Metal Articulation
- Sponsor
- Biomet Orthopedics, LLC
Skin Resurfacing
Unipolar Microplasma Radiofrequency Device: In-vivo Histologic Study
Prospective, Open-Label, Single-Center Pilot Study. The study is aimed to evaluate the histologic effects of a unipolar microplasma electrode pin radiofrequency device (Alma Lasers OPUS system) on the abdominal skin.
- Trial name
- NCT04153071
- Testing
- OPUS system
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Alma Lasers
Skin Laxity
Assess Efficacy of a Nanodiamond Periprocedural Skin Care Regimen for Ablative Resurfacing
The primary objective of this study is to evaluate the efficacy and tolerability of Pavise Extracellular Matrix Restore (ECMR), compared with standard acute post-operative care, when used as the primary occlusive treatment…
- Trial name
- NCT07462533
- Testing
- Pavise Serum, Co2/Er:YAG
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Osteoarthritis, Avascular Necrosis
Cormet Post-PMA Study: New Enrollment
The primary objective of this study is to evaluate the performance of the Cormet Hip Resurfacing implant system in the post-approval environment.
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis
- Trial name
- PASNew (NCT00722007)
- Testing
- Cormet Hip Resurfacing
- Where
- 6 sites in United States
- Volunteers
- 147 people
- Sponsor
- Corin
Subjects With Severe, Refractory Sclerotic Skin Changes
Ablative Fractional Laser for Sclerotic GVHD-Associated Joint Contractures
Graft versus host disease (GVHD) is a common complication of allogeneic stem cell transplant.Chronic GVHD is characterized by skin thickening and tightening.
- Trial name
- NCT02881047
- Testing
- CO2 Laser, Ultrasound, Skin Biopsy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Post-Acne Atrophic Scars, Carbon Dioxide Lasers
PRP Plus Fractional CO₂ Laser for Acne Scars
This randomized controlled trial aims to evaluate whether adding platelet-rich plasma (PRP) to fractional CO₂ laser resurfacing improves the treatment of moderate-to-severe acne scars compared with laser alone.
- Conditions
- Post-Acne Atrophic Scars, Carbon Dioxide Lasers, Platelet-Rich Plasma
- Trial name
- PRPLT (NCT07352215)
- Testing
- Fractional CO₂ Laser + Platelet-Rich Plasma (PRP), Fractional CO₂ Laser Only
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Gujranwala medical college District Headquarters Hospital, Gujranwala
Skin Aging, Transepidermal Water Loss
Microneedle Versus Fractional CO₂ Laser for Skin Aging Treatment With Stem Cell Secretome in Indonesian Adult Women
Evidences regarding the effectiveness of adipose-derived mesenchymal stem cells (ADMSCs) secretome to alleviate skin aging have been extensively available, yet no studies hitherto directly investigated the best administration…
- Trial name
- NCT05508191
- Testing
- Fractional CO₂ Laser, Microneedle
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shannaz Nadia Yusharyahya
Rheumatoid Arthritis, Osteoarthritis
A Single Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery
The purpose of this study is to monitor the performance and determine the metal ion release of the DePuy ASR™ System in the treatment of patients with hip joint disease requiring hip resurfacing surgery.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders
- Trial name
- NCT00872794
- Testing
- DePuy ASR™ Hip System
- Where
- South Africa
- Volunteers
- 50 people
- Sponsor
- DePuy International
Wrinkle
Safety and Efficacy of the BTL-754 Device for Laser Skin Resurfacing Treatment of the Face
This study will evaluate the clinical safety and the performance of the BTL-754 device (equipped with the 754-4 applicator) for reduction of facial wrinkles by the means of laser skin resurfacing treatment.
- Trial name
- NCT06158438
- Testing
- BTL-754-4 Treatment
- Where
- Bulgaria
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Scar, Hidradenitis Suppurativa
Fractional CO2 Laser Fenestration and Steroid Delivery in HS Lesions
Assess the efficacy of fractional ablative CO2 therapy combined with topical steroids in HS patients with Hurley stage I or stage II disease.
- Trial name
- NCT05580029
- Testing
- Triamcinolone Topical, Fractional Ablative CO2 Therapy, EMLA 5% cream
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Rheumatoid Arthritis, Osteoarthritis
Multi-Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Resurfacing and Primary Total Hip Replacement
The purpose of this study is to monitor the performance of a large metal-on-metal bearing from the DePuy ASR™ System in the treatment of patients with hip joint disease requiring hip resurfacing surgery or a total hip…
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders
- Trial name
- NCT00872547
- Testing
- DePuy ASR™ Hip System, DePuy ASR™ XL Head / ASR™ Acetabular Cup System
- Where
- 8 sites in Austria, Czechia and 6 more
- Volunteers
- 329 people
- Sponsor
- DePuy International
Skin Disorders
Tolerability of Using a Post-Treatment Topical Adjuvant Combination Following Fractional Radiofrequency Ablation
The purpose of this study is to compare the tolerability of the application of a combination of a serum containing human bone marrow stem cell derived growth factor (SCR Complex) and cytokines and a botanical lipid-based…
- Trial name
- NCT02896569
- Testing
- Topical combination therapy
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Osteoarthritis, Rheumatoid Arthritis
A Clinical Investigation of the Copeland™ Humeral Resurfacing Head
The purpose of this study is to perform a five-year, prospective evaluation of the Copeland™ Humeral Resurfacing Head Prosthesis for outcome and durability.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Avascular Necrosis, Humeral Fractures
- Trial name
- NCT00698750
- Volunteers
- 34 people
- Sponsor
- Biomet Orthopedics, LLC
Skin Texture, Pigmented Lesions
Nonablative Fractional Diode Laser for Treatment of Skin Resurfacing and Pigmented Lesions
This study is intended to evaluate the efficacy and safety of a new diode fractional laser for skin resurfacing and treatment of pigmented lesions.
- Trial name
- NCT04203745
- Testing
- Nonablative Fractional Diode Laser
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Freckles
Efficacy and Safety of Fractional Carbon Dioxide Laser for Treatment of Facial Freckles.
Freckles are clusters of melanin in the superficial epidermis. They affect mostly face and sun exposed areas, and appear as flat brown or red macules that fade in winter, usually in a fair complexion patient, but may be present…
- Trial name
- NCT01545869
- Testing
- Fractional carbon dioxide laser
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Wrinkle, Rhytides
Healing Study of Fractional Skin Resurfacing and Tissue Histopathology After Ellacor Treatment
The goal of this study is to observe the healing of skin after ellacor® treatment at different timepoints, depths and coring densities.
- Conditions
- Wrinkle, Rhytides, Histopathology
- Trial name
- NCT06502470
- Testing
- ellacor® Micro-Coring procedure
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Cytrellis Biosystems, Inc.
Cartilage Disease
BioPoly® RS Partial Resurfacing Patella Registry Study
The data registry will increase the knowledge of outcomes for treatment of focal cartilage defects of the patella treated with the BioPoly RS Patella Implant and will allow monitoring of the clinical safety and performance of the…
- Trial name
- NCT02991300
- Testing
- BioPoly RS Partial Resurfacing Patella Implant
- Where
- 2 sites in United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- BioPoly LLC
Rhytids, Skin Laxity
Safety and Efficacy of 2910 nm Fiber Laser Resurfacing and Laser-Coring
The primary objective of this clinical trial is to evaluate the safety and effectiveness of the 2,910 nm mid-infrared erbium-doped fluoride fiber glass laser (UltraClear, Acclaro Medical) for non-invasive dermatological aesthetic…
- Trial name
- NCT07254884
- Testing
- 2,910 nm mid-infrared erbium-doped fluoride fiber glass laser (UltraClear, Acclaro Medical)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- FA Corporation