Clinical trials: Skin Sensitization
Cumulative Irritation and Sensitization
Study Will Assess Skin Irritation and Sensitization for HP-1050 Patch
A randomized, evaluator-blinded study to assess skin irritation and skin sensitization of HP-1050 transdermal system (HP-1050) in comparison to XULANE patch in healthy female volunteers.
- Trial name
- NCT04624867
- Testing
- HP-1050 Patch
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Noven Pharmaceuticals, Inc.
Irritation/Irritant, Sensitisation
Human Skin Safety Testing of 6 Mitopure Topical Products Using a Human Repeat Insult Patch Test (HRIPT) in Healthy Volunteers
The objective of this study is to investigate the irritation and sensitization potential of 6 different topically applied test articles containing Mitopure in a shared panel of healthy volunteers by means of repeated cutaneous…
- Trial name
- GLOW-Safety-3 (NCT07100912)
- Testing
- Mitopure Topical Formula 5, Mitopure Topical Formula 6, Mitopure Topical Formula 7
- Where
- United Kingdom
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Dermatitis
Prevalence of Skin Sensitization and Dermatitis Among Epoxy-exposed Workers in the Wind Turbine Industry.
The goal of this observational study it to learn about the prevalence of skin sensitization and dermatitis among epoxy-exposed workers in the wind turbine industry.
- Trial name
- EPOXY (NCT05891743)
- Testing
- Patch Test
- Where
- Portugal
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Siemens Gamesa Renewable Energy Blades, S.A.
Asthma, Eczema
Fish Oil Supplementation During Pregnancy for Prevention of Asthma, Eczema and Allergies in Childhood
The aim of this study is to prevent asthma and allergies in childhood by supplementation with fish oil (n-3 fatty acids) to the mother during pregnancy.
- Conditions
- Asthma, Eczema, Allergy
- Trial name
- NCT00798226
- Testing
- n-3 fatty acid, olive oil
- Where
- 2 sites in Denmark
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Copenhagen Studies on Asthma in Childhood
Sensitivity, Contact, Photosensitivity
Dermatological Assessment of Primary Dermal Irritability Accumulated, Sensitization, Photoallergy and Photosensitization of a Scar Gel
Evaluate the potential of Primary Dermal Irritability, Accumulated Dermal Irritability, Dermal Sensitization, Photoallergy and Photosensitization, of health products through the application of Patch Test, proving the safety of…
- Conditions
- Sensitivity, Contact, Photosensitivity, Phototoxicity
- Trial name
- NCT06723340
- Testing
- Scar gel
- Where
- Brazil
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Herbarium Laboratorio Botanico Ltda
Skin Irritability
Dermatological Evaluation of Topical Compatibility, Primary Skin Irritability, Accumulated Skin Irritability, and Dermal Sensitisation
Check the safety under normal conditions of use through the verification of emergence signs of irritability and sensitisation of the genital mucosa.
- Trial name
- DERM EV TOPIC (NCT02419248)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Kley Hertz S/A
Skin Sensitisation
Skin Sensitisation (Modified Draize-95 Test)
Skin Sensitization Test (Modified Draize-95) to Support a Low Dermatitis Potential Claim for a Powder Free Polychloroprene Surgical Gloves, Sterile.
- Trial name
- MDT-95 (NCT04402476)
- Testing
- Powder Free Polychloroprene Surgical Gloves, Sterile. Low Dermatitis Potential, tested for use with Chemotherapy drugs.
- Where
- Malaysia
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- PT. Medisafe Technologies
Irritation/Irritant, Sensitisation
Human Skin Safety Testing of a Mitopure Topical Product Using a Human Repeat Insult Patch Test (HRIPT) in Healthy Volunteers
The objective of this study is to investigate the irritation and sensitization potential of multiple topically applied test articles (containing different concentrations of Mitopure), in a shared panel of healthy volunteers by…
- Trial name
- GLOW-Safety (NCT05079607)
- Testing
- Mitopure Topical Formula 1, Mitopure Topical Formula 2
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Hyperalgesia, Secondary
Reliability of Measuring the Area and Intensity of Secondary Hyperalgesia Induced by High Frequency Stimulation
This study is designed to evaluate the method of assessing the and intensity areas of secondary hyperalgesia induced by High Frequency Stimulation (HFS).
- Trial name
- NCT03966508
- Testing
- High-frequency electrical stimulation
- Where
- Belgium
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Irritation/Irritant, Sensitisation
Human Skin Safety Testing of 1 Mitopure Topical Products Using a Human Repeat Insult Patch Test (HRIPT) in Healthy Volunteers
The objective of this study is to investigate the irritation and sensitization potential of 1 topically applied test article containing Mitopure in a shared panel of healthy volunteers by means of repeated cutaneous patch…
- Trial name
- GLOW-Safety-4 (NCT07517874)
- Testing
- Mitopure Topical Formula 11
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Skin Irritability, Skin Sensitization
Safety Dermatological Assessment of Topical Use Product Through Dressings Predictive Studies for Evaluation of Photoirritation and Dermal Photosensitivity
The purpose of this study is to prove the product tested does not cause photoirritation or photosensitization reactions when exposed to sun light.
- Trial name
- SAF DER ASSESS (NCT02441608)
- Testing
- KL029 Intimate Lubricant Gel
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Kley Hertz S/A
Healthy
Bovine Atelocollagen Skin Sensitization Test
Bovine atelocollagen skin testing of healthy adult volunteers to investigate the potential of allergy to atelocollagen medical device implants
- Trial name
- NCT05235087
- Testing
- Bovine atelocollagen intradermal injection
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- AscentX Medical, Inc.
Skin Care
Evaluation of Skin Irritancy and Sensitization of a Liquid Bandage
The investigational product constitutes a medical device that is freely accessible to consumers and, as such, must be safe under real or reasonably foreseeable conditions of use and its safety must be tested before being placed…
- Trial name
- NCT05876546
- Testing
- Liquid bandage, Saline Solution
- Where
- 2 sites in Brazil
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Eurofarma Laboratorios S.A.
Sensitivity, Contact
Dermatological Assessment of Primary Dermal Irritability Accumulated and Sensitization
This is a clinical study for health care product safety assessment. The research will be conducted with 92 subjects, aged 18 to 59 years.
- Trial name
- NCT04248556
- Testing
- Health care product
- Where
- Brazil
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Herbarium Laboratorio Botanico Ltda
Skin Irritation
Repeat Insult Patch Test of Skin Irritation/Sensitization for Cetaphil Dermacontrol Oil Control Moisturizer SPF 30
Determine if Cetaphil DermaControl Oil Control Moisturizer SPF 30 proves to be a contact sensitizer or irritant in certain individuals
- Trial name
- NCT01887808
- Testing
- Cetaphil DermaControl Oil Control Moisturizer SPF 30
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Asthma, Dermatitis, Atopic
Impact in Off-spring of Mothers After Perinatal Daily Intake of a Probiotic
A probiotic (Lactobacillus rhamnosus GG) supplement to pregnant women the last four weeks of pregnancy and three months after birth is expected to give a 40% reduction in risk of atopic sensitisation and allergic disease at two…
- Conditions
- Asthma, Dermatitis, Atopic, Rhinitis, Allergic, Perennial
- Trial name
- NCT00159523
- Testing
- Probiotic
- Where
- Norway
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Skin Lesion, Skin Lesions
Assessment of EF192A Potential Sensitization and Accumulated and Primary Irritability in Controlled/Maximized Conditions
The investigational product constitutes a medical device that is freely accessible to consumers and, as such, must be safe under real or reasonably foreseeable conditions of use and its safety must be tested before being placed…
- Conditions
- Skin Lesion, Skin Lesions, Skin Care
- Trial name
- Spray A (NCT06731062)
- Testing
- EF192A, Saline solution
- Where
- Brazil
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Eurofarma Laboratorios S.A.
Sensitivity, Contact
Dermatological Assessment of Primary Dermal Irritability Accumulated and Sensitization of Hyaluronic Nasal Spray
Evaluate the potential of Primary Dermal Irritability, Accumulated Dermal Irritability and Dermal Sensitization, of health products through the application of Patch Test, proving the safety of the product for topical use.
- Trial name
- NCT05508243
- Testing
- Hyaluronic Nasal Spray
- Where
- Brazil
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Herbarium Laboratorio Botanico Ltda
Skin Sensitization
Human Repeat Insult Patch Test of Wound Dressings
The purpose of this study is to determine whether contact sensitization occurs to the skin of normal healthy human subjects, by repetitive application of IV Clear™, Tegaderm CHG™ and Silicone Vehicle Control dressings.
- Trial name
- NCT01368146
- Testing
- IV Clear™, Tegaderm CHG™, Silicone Vehicle Control Dressing
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Covalon Technologies Inc.
Skin Care
To Evaluate Skin Irritation and Skin Sensitisation of Developmental Cosmetic Facial Products
The aim of this study is to assess irritant or allergic response of 3 developmental cosmetic facial products following a conventional human repeated insult patch test methodology for 6 weeks.
- Trial name
- NCT04007159
- Testing
- Serum, Lotion, Cream
- Where
- Brazil
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline