Clinical trials: Skin Testing
Arthritis, Psoriatic
A Study to Test Different Doses of BI 730357 and Find Out Whether They Reduce Symptoms in People With Active Psoriatic Arthritis
This study is open to adults with active psoriatic arthritis who have tender and swollen joints. The purpose of this study is to find out whether a medicine called BI 730357 helps to reduce symptoms and to prevent damage to…
- Trial name
- NCT04680676
- Testing
- BI 730357
- Sponsor
- Boehringer Ingelheim
Lichen Planus
Mucosal and Nasal Involvement and Their Correlation With Smell and Taste Functions in Lichen Planus Patients
This study investigates smell and taste function in patients diagnosed with lichen planus, a chronic inflammatory condition affecting the skin and mucous membranes.
- Trial name
- LP-NOSE (NCT07570706)
- Testing
- Grup 1 - Lichen Planus Patients Intervention Name: Taste and Smell Testing, Oral and Nasal Examination, Nasal Endoscopy Intervention Description: Participants undergo taste and smell testing to assess
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Anxiety, Fear Anxiety
Effect of AI(Artificial Intelligence)-Based Storytelling Video on Anxiety and Fear During Skin Prick Test in Children
This study evaluates the effectiveness of an AI-generated therapeutic storytelling video on pre-procedural anxiety and fear levels in children aged 4 to 10 years undergoing their first Skin Prick Test (SPT).
- Conditions
- Anxiety, Fear Anxiety, Allergic Rhinitis, Asthma (Diagnosis)
- Trial name
- NCT07453615
- Testing
- AI-Generated Storytelling Video, Standard Clinic Care
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Antalya Training and Research Hospital
Advanced Cancer
A Study to Test the Safety and Effectiveness of Nivolumab Combined With Daratumumab in Patients With Pancreatic, Non-Small Cell Lung or Triple Negative Breast Cancers, That Have Advanced or Have Spread
The purpose of this study is to determine whether a combination of Nivolumab and Daratumumab is safe and effective when treating Pancreatic, Non-Small Cell Lung or Triple Negative Breast Cancers, that have advanced or have spread.
- Trial name
- NCT03098550
- Testing
- Nivolumab, Daratumumab
- Where
- 20 sites in United States, Australia and 7 more
- Volunteers
- 105 people
- Sponsor
- Bristol-Myers Squibb
Melanoma, Neoplasm Metastasis
ADI-PEG in Patients With Metastatic Melanoma
This is a study to determine the safety and toxicity of increasing doses of arginine deiminase combined to polyethylene glycol (ADI-PEG) in patients with nonresectable metastatic melanoma.
- Trial name
- NCT00029900
- Testing
- ADI PEG
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- FDA Office of Orphan Products Development
Skin Pigment, Skin Red
Skin Efficacy Testing of Astrion Products
This project aims to conduct safety and efficacy tests on the skin for the ingestion of Astrion Vitality Capsules, containing A. membranaceus and C. Asiatica roots, and the topical application of Astrion Vitality Cream.
- Trial name
- NCT06657352
- Testing
- ACS Topical Treatment Group, Oral Treatment + Topical Treatment Group, ACS Oral Treatment Group
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chia Nan University of Pharmacy ＆ Science
Breast Neoplasms, Breast Cancer
Testing BRCA 1/2 Mutation Using Next Generation Sequencing
Testing BRCA 1/2 mutation is important for patients with breast cancer, and Sanger sequencing is a standard method to identify BRCA 1/2 mutation.
- Trial name
- BRCANGS (NCT02151747)
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Severance Hospital
Psoriasis
Study to Test the Effectiveness of a New Treatment for Scalp Psoriasis
The purpose of this study is to test the effectiveness of DermiPsor's DPS-102 (test product) in patients with scalp Psoroasis. The study is also intended to assess the safety of the product.
- Trial name
- NCT01368887
- Testing
- DPS-102, Calcipotriol Monotherapy, Nicotinamide Monotherapy
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- DermiPsor, Ltd.
Metastatic Melanoma, Stage IIIB Cutaneous Melanoma AJCC v7
Imiquimod and Pembrolizumab in Treating Patients With Stage IIIB-IV Melanoma
This pilot early phase I trial studies the side effects and how well imiquimod and pembrolizumab work in treating patients with stage IIIB-IV melanoma. Imiquimod may stimulate the immune system.
- Conditions
- Metastatic Melanoma, Stage IIIB Cutaneous Melanoma AJCC v7, Stage IIIC Cutaneous Melanoma AJCC v7, Stage IV Cutaneous Melanoma AJCC v6 and v7
- Trial name
- NCT03276832
- Testing
- Imiquimod, Biopsy, Pembrolizumab
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Mayo Clinic
Tuberculosis
Study of Pre-clearance of Latent Tuberculosis Infection And BCG Revaccination
The purpose of this research is to further study the tuberculosis (TB) vaccine, Bacillus Calmette Guérin (BCG). The goal of this study is to evaluate whether the BCG vaccine is more effective in preventing TB in adults if it is…
- Trial name
- NCT01119521
- Testing
- BCG strain Danish, Isoniazid
- Where
- South Africa
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Facial Photoaging, Deepening of Facial Wrinkles
Regenmedic Cream 2.0 12-week Long-term Clinical Test
The goal of this study is to evaluate the anti-wrinkle, firming, moisturizing and repairing efficacy of a test facial cream after single use and 12 weeks of continuous use via clinical evaluation, instrumental measurement, image…
- Conditions
- Facial Photoaging, Deepening of Facial Wrinkles, Skin Laxity, Decreased Skin Elasticity
- Trial name
- NCT07874113
- Testing
- Test facial cream (topical skin care product)
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Malaria
Clinical Performance Evaluation of Fyodor Urine Malaria Test (UMT)
The purpose of this study is to evaluate the clinical performance of the one-step Fyodor Urine Malaria Test (UMT), to determine its accuracy (sensitivity and specificity) for the diagnosis of Plasmodium falciparum malaria in…
- Trial name
- NCT01921413
- Testing
- Urine Malaria Test
- Where
- Nigeria
- Volunteers
- 1,893 people, healthy volunteers welcome
- Sponsor
- Fyodor Biotechnologies Inc
Melanoma
Vaccine Therapy in Treating Patients With Stage IV or Relapsed Malignant Melanoma
RATIONALE: Vaccines made from peptides may make the body build an immune response to kill tumor cells. PURPOSE: Phase I/II trial to study the effectiveness of vaccine therapy in treating patients who have stage IV, or relapsed…
- Trial name
- NCT00005617
- Testing
- dendritic cell-MART-1 peptide vaccine, leukapheresis
- Where
- United States
- Sponsor
- Jonsson Comprehensive Cancer Center
Healthy
A 6-Week Study to Evaluate the Photoallergic Potential of Diacerein 1% Ointment in Healthy Volunteers
A study in healthy male and female adult volunteers to determine the potential of diacerein 1% ointment to induce a photoallergic skin reaction using a controlled photopatch testing procedure.
- Trial name
- NCT03473197
- Testing
- Diacerein 1% ointment
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Castle Creek Pharmaceuticals, LLC
Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
This phase III trial compares the effectiveness of fractionated stereotactic radiosurgery (FSRS) to usual care stereotactic radiosurgery (SRS) in treating patients with cancer that has spread from where it first started to the…
- Conditions
- Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma, Metastatic Digestive System Carcinoma, Metastatic Lung Non-Small Cell Carcinoma
- Trial name
- NCT06500455
- Testing
- Computed Tomography, Fractionated Stereotactic Radiation Therapy, Magnetic Resonance Imaging
- Where
- 270 sites in United States, Canada and 2 more
- Volunteers
- 274 people
- Sponsor
- NRG Oncology
Varicella Zoster Virus Infection, Herpes Simplex Virus Infection
Palatability Testing of a New Paediatric Formulation of Valacyclovir
Palatability testing of a new paediatric formulation of valacyclovir in children 4-12 years of age and at least one of their parents.
- Trial name
- VALID-0 (NCT01682109)
- Testing
- Valacyclovir
- Where
- Netherlands
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Cutaneous Leishmaniasis, Skin Diseases, Parasitic
Accuracy of a Rapid Diagnostic Test for Cutaneous Leishmaniasis in Morocco
The aim of this study is to estimate the accuracy of CL Detect Rapid Test™ compared to a composite reference standard test (Direct examination of skin smears + PCR test) in patients with clinically suspected Cutaneous…
- Conditions
- Cutaneous Leishmaniasis, Skin Diseases, Parasitic, Neglected Diseases
- Trial name
- NCT02979002
- Where
- 9 sites in Morocco
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- National School of Public Health, Morocco
Knee Pain, Chronic Osteoarthritis
ROSA Total Knee Investigational Testing Authorization Study
This is a prospective, single-center clinical study designed to facilitate the collection and evaluation of workflow efficiency, patient pain and function, and adverse event data.
- Conditions
- Knee Pain, Chronic Osteoarthritis, Avascular Necrosis of Femoral Condyle, Moderate Varus, Valgus or Flexion Deformities
- Trial name
- NCT03970629
- Testing
- PERSONA Total Knee
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Skin Care
To Evaluate Skin Irritation and Skin Sensitisation of Developmental Cosmetic Facial Products
The aim of this study is to assess irritant or allergic response of 3 developmental cosmetic facial products following a conventional human repeated insult patch test methodology for 6 weeks.
- Trial name
- NCT04007159
- Testing
- Serum, Lotion, Cream
- Where
- Brazil
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Breast Cancer
Radiation Therapy in Treating Women Who Have Undergone Breast Conservation Surgery and Systemic Therapy for Early Breast Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Specialized radiation therapy, such as intensity-modulated radiation therapy, that delivers a high dose of radiation directly to the tumor may kill more…
- Trial name
- NCT00818051
- Testing
- intensity-modulated radiation therapy
- Where
- United Kingdom
- Volunteers
- 840 people
- Sponsor
- Institute of Cancer Research, United Kingdom
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