Clinical trials: Skin Tests
Immune Thrombocytopenia
This Clinical Study is to Test Efficacy and Safety of BT595 in Chronic Primary Immune Thrombocytopenia (ITP)
The main purpose of this study is to assess the efficacy and safety of BT595 in adult subjects with chronic ITP. The primary objective of this study is to determine the rate of subjects with a response.
- Trial name
- NCT02859909
- Testing
- BT595
- Where
- 22 sites in Bulgaria, Czechia and 4 more
- Volunteers
- 34 people
- Sponsor
- Biotest
Acne, Post-inflammatory Hyperpigmentation
Clinical Efficacy of the Product in the Management of Facial Post Inflammatory Hyperpigmentation (PIHP) Subjects
Double-blind, randomized, clinical study is designed to evaluate the efficacy of Niacinamide A in the management of facial Post Inflammatory Hyper Pigmentation (PIHP) in healthy female and male subjects with moderate to severe…
- Trial name
- NCT06822335
- Where
- Mauritius
- Volunteers
- 65 people
- Sponsor
- Cosmetique Active International
Erythema, Edema
Human Repeat Insult Patch Test to Evaluate Personal Lubricants
The purpose of this test is to evaluate the sensitizing potential of a personal lubricant, as a result of repeated occlusive patch.
- Trial name
- HRIPT (NCT02737631)
- Testing
- "Chameleon" Personal Lubricant
- Where
- United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Skin Sensitisation
Skin Sensitization Test (Modified Draize-95 Test)
Skin Sensitization Test (Modified Draize-95 Test) to Support a Low Dermatitis Potential Claim for a Blue Non Sterile Powder Free Nitrile Examination Gloves.
- Trial name
- NCT03886987
- Testing
- Blue Non Sterile Powder Free Nitrile Examination Gloves
- Where
- United States
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Central Medicare Sdn. Bhd.
Eczema
A 47 Hour Occlusive Cutaneous Skin Patch Test on Adult Subjects With Dry/Atopic Skin
This is an open label, non-comparative investigation to determine the tolerance of Eczema Repair Emollient on healthy subjects with dry/atopic and very dry/atopic skin.
- Trial name
- NCT02620293
- Testing
- Eczema Repair Emollient
- Where
- Germany
- Volunteers
- 33 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Allergy to Mites
Biological Standardization of Blomia Tropicalis Allergen Extract
The objective of this study is to determine the biologic activity of a Blomia tropicalis allergen extract in histamine equivalent prick (HEP) units, in order to be used as in-house reference preparation (IHRP).
- Trial name
- NCT01597752
- Testing
- Four different concentrations of Blomia tropicalis allergen extract, positive control and negative control
- Where
- 2 sites in Spain
- Volunteers
- 20 people
- Sponsor
- Laboratorios Leti, S.L.
Dermatitis, Atopic
A Study to Test the Long-term Safety of BI 655130 in Patients With Atopic Eczema Who Took Part in Study 1368-0032
To assess the long term safety and efficacy of treatment with BI 655130 in patients with AD who have completed and have responded to treatment in the parent study 1368-0032
- Trial name
- NCT04086121
- Testing
- Spesolimab
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 14 people
- Sponsor
- Boehringer Ingelheim
Irritation/Irritant, Sensitisation
Human Skin Safety Testing of a Mitopure Topical Product Using a Human Repeat Insult Patch Test (HRIPT) in Healthy Volunteers
The objective of this study is to investigate the irritation and sensitization potential of multiple topically applied test articles (containing different concentrations of Mitopure), in a shared panel of healthy volunteers by…
- Trial name
- GLOW-Safety (NCT05079607)
- Testing
- Mitopure Topical Formula 1, Mitopure Topical Formula 2
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Hypersensitivity
Study to Determine Skin Irritation Potential of an Antifungal Cream Containing Trolamine After Repeated Skin Application (Cumulative Irritation Patch Test)
In this study researchers want to study the potential skin reaction after repeated application of an antifungal cream containing trolamine.
- Trial name
- NCT04531813
- Testing
- Butenafine HCl 1% (BAY1896425), Positive Control-Sodium lauryl sulfate (SLS), Negative Control
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bayer
Advanced Solid Tumor
A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors
This study will evaluate the safety, efficacy, optimal dose, and pharmacokinetics (PK) of BNT326 as monotherapy (Part 1) and as combination treatment with immunotherapeutic agents (Part 2) in participants with histologically or…
- Trial name
- NCT07070232
- Testing
- BNT326, Pumitamig, Itraconazole
- Where
- 77 sites in United States, Australia and 7 more
- Volunteers
- 1,438 people
- Sponsor
- BioNTech SE
Antimicrobial Effectiveness
Topical Antimicrobial Effectiveness Testing
The primary objective of this study is to measure the antimicrobial effectiveness of ChloraPrep one-Step.
- Trial name
- NCT01314703
- Testing
- ChloraPrep One-Step, 70% isopropyl alcohol
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- C. R. Bard
Psoriasis
This Study is Done in Patients With Plaque Psoriasis and Tests How Well They Tolerate BI 730357 and How Effective it is
The primary objective is based on Week 12 co-primary endpoints of PASI (Psoriasis Area and Severity Index) 75 and sPGA (Static Physician's Global Assessment) 0/1, and overall safety Secondary objectives of Part 1 are to evaluate…
- Trial name
- NCT03635099
- Testing
- BI 25 mg (fasted), BI 50 mg (fasted), BI 100 mg (fasted)
- Where
- 34 sites in United States, Canada and 1 more
- Volunteers
- 274 people
- Sponsor
- Boehringer Ingelheim
Pain
A Study to Assess Therapeutic Equivalence Between Test EMLA Patch With Marketed EMLA Patch in Healthy Subjects.
A double-blind, randomized, 2-period, placebo-controlled, single-center, crossover study, efficacy study demonstrating the therapeutic equivalence of the test cellulose disc (matrix) in EMLA patch and the current commercial…
- Trial name
- EMLA (NCT03313336)
- Testing
- EMLA test patch, EMLA current reference patch
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Atopic Dermatitis
CT 327 in the "Atopy Patch Test" Model
A Randomized, Double-Blind, Phase I, Single-Center Study on the Efficacy and Safety of CT 327 in the Atopy Patch Test model.
- Trial name
- CT327 AD01-09 (NCT01368315)
- Testing
- CT327 application, Active comparator, No intervention
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Creabilis SA
Allergic Contact Dermatitis
Bioequivalence of Ethylenediamine Dihydrochloride Study
The purpose of this study is to compare the allergen ethylenediamine dihydrochloride when prepared using methylcellulose versus preparation using polyvinylpyrrolidone.
- Trial name
- NCT01798589
- Testing
- Ethylenediamine dihydrochloride allergen patch
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Allerderm
Hyperpigmentation
Efficacy and Tolerability of the Tested Formula After 3 Months in Treatment of Facial Hyperpigmentation of 3 Origins
The objective of this study is to evaluate the efficacy, cosmetic acceptability and improvement of the stigmatization of the tested product (2039125 03) used bis in die (BID) for 3 months in adult patients suffering from mild to…
- Trial name
- NCT06268496
- Testing
- serum formula 2039125 03
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Systemic Lupus Erythematosus
A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)
This study is open to adults with systemic lupus erythematosus (SLE). The purpose of this study is to find out whether a medicine called BI 3000202 helps people with SLE.
- Trial name
- NCT07409181
- Testing
- BI 3000202
- Where
- 139 sites in United States, Argentina and 19 more
- Volunteers
- 405 people
- Sponsor
- Boehringer Ingelheim
Pressure Ulcers
A Test of the Investigational SEM Scanner
The objective of this study is to establish required data for SEM Scanner analysis of the readings given by the SEM Scanner in the target patient population..
- Trial name
- NCT01965444
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Bruin Biometrics, LLC
Allergic Rhinitis, Conjunctivitis
Efficacy of the Anti-Bet v 1 Monoclonal Antibodies (Given Subcutaneously) to Reduce Allergic Rhinitis and Conjunctivitis Symptoms and Skin Test Reactivity Upon Exposure to Birch Allergen in Adult Participants
Primary objective: To assess the efficacy of a single dose of the anti- Bet v 1 monoclonal antibodies (mAb(s ) in the reduction of allergic nasal symptoms during an out-of-season birch allergen environmental exposure unit (EEU)…
- Trial name
- NCT05430919
- Testing
- REGN5713, REGN5714, REGN5715
- Where
- 3 sites in Canada
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
Non-Transfusion Dependent Beta-Thalassemia (NTDT)
A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body
This study is researching an experimental drug called REGN7999 (called "study drug"). The study is focused on patients with non-transfusion dependent beta-thalassemia.
- Trial name
- FERVENT-1 (NCT06421636)
- Testing
- REGN7999
- Where
- 26 sites in United States, Georgia and 7 more
- Volunteers
- 19 people
- Sponsor
- Regeneron Pharmaceuticals