Clinical trials: Skin Tests
Tuberculosis
Local Anesthesia and Tuberculin Skin Test in Infants and Children
The use of local anaesthesia efficiently reduces pain due to needle puncture. However, when tuberculin skin test is performed it is the skin reaction to tuberculin injection that is studied.
- Trial name
- NCT00309673
- Testing
- lidocaine / Prilocaine
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Scleroderma, System; Sclerosis
Rehabilitation Program in Patients With Scleroderma
Scleroderma (or Systemic Sclerosis - SSc) is one of the most neglected diseases worldwide, according to the World Health Organization.
- Conditions
- Scleroderma, System; Sclerosis, Muscle Strain, Physical Disability
- Trial name
- NCT05041868
- Testing
- Treatment
- Where
- Brazil
- Volunteers
- 104 people
- Sponsor
- Centro Universitário Augusto Motta
Skin Lesion, Skin Lesions
Assessment of EF192A Potential Sensitization and Accumulated and Primary Irritability in Controlled/Maximized Conditions
The investigational product constitutes a medical device that is freely accessible to consumers and, as such, must be safe under real or reasonably foreseeable conditions of use and its safety must be tested before being placed…
- Conditions
- Skin Lesion, Skin Lesions, Skin Care
- Trial name
- Spray A (NCT06731062)
- Testing
- EF192A, Saline solution
- Where
- Brazil
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Eurofarma Laboratorios S.A.
Breast Cancer Female
Cognitive Rehabilitation Following Breast Cancer Treatment
The goal of this proposed project is to evaluate the feasibility and preliminary effect of metacognitive strategy training to improve activity performance, cognition, and quality of life in breast cancer survivors with…
- Trial name
- NCT06545045
- Testing
- Metacognitive Strategy Training (MCST), Inactive Control Group
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Missouri-Columbia
Dry Skin, Sensitive Skin
A Clinical Study to Assess the Safety, In-use Tolerability of Test Product in Healthy Adult Subjects With Dry and Sensitive Skin.
This is open-label, interventional, prospective, safety in-use tolerability study of test product "No Rays, Thanks Mineral Sunscreen" in healthy adult human subjects with dry and sensitive skin.
- Trial name
- NCT06489600
- Testing
- No Rays, Thanks Mineral sunscreen
- Where
- India
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Diabetic Foot Ulcer
Non-Invasive Testing to Evaluate Wound Healing in Diabetes
Normal group: We will collect normative data from healthy individuals to include baseline data, screening, and images. Up to 500 people will be enrolled and can include normal healthy volunteers, staff and students/trainees.
- Trial name
- NCT04232631
- Testing
- SnapshotNIR, Kent Imaging
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Exercise Training, Breast Cancer
Moderate-Intensity Exercise and Pain Sensitization in Breast Cancer Survivors: A Case-Based Study
The aim of this study was to evaluate the feasibility, safety, and acceptability of a supervised, combined moderate-intensity aerobic and resistance training program designed to reduce pain sensitization in BCS with persistent…
- Conditions
- Exercise Training, Breast Cancer, Pain Management
- Trial name
- NCT07128030
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Universidad Rey Juan Carlos
Lipedema
Validity and Reliability of the Turkish Duke Activity Status Index in Women With Lipedema
This study aims to evaluate the validity and reliability of the Turkish version of the Duke Activity Status Index (DASI) in women with lipedema.
- Trial name
- DASI-LIP (NCT07803913)
- Testing
- Duke Activity Status Index (DASI)
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istanbul University - Cerrahpasa
Wound Healing
Patch Test of Benzalkonium Chloride Disinfectant Spray
The aim of the study is to evaluate the irritation potential of benzalkonium chloride disinfectant spray when placed in contact with normal human skin.
- Trial name
- NCT01762982
- Testing
- 0.13% Benzalkonium Chloride, SLS Solution, Normal Saline Water
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pemphigus
Treatment of Pemphigus Patients With Rituximab 1000mgX2 and Assessment of Immune Status Via Cylex
The purpose of this study is to determine whether Rituximab, in the same doses as used in rheumatoid arthritis patients, will benefit pemphigus patients.
- Trial name
- NCT01338103
- Testing
- Rituximab
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Rabin Medical Center
Breast Cancer
Mindfulness Based Couples Therapy
The goal of this study is to explore the effects of a Mindfulness Based Couples Intervention on relationship satisfaction with quality of life and immune system function among breast cancer survivors and their partners.
- Trial name
- NCT02349217
- Testing
- Mindfulness-Based Relationship Enhancement (MBRE), Self-Help Materials, Pain Assessment
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8
Testing the Addition of Navitoclax to the Combination of Dabrafenib and Trametinib in People Who Have BRAF Mutant Melanoma
This phase I/II trial studies the side effects and best dose of dabrafenib, trametinib, and navitoclax and to see how well they work in treating patients with BRAF mutant melanoma or solid tumors that has spread from where it…
- Conditions
- Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8, Malignant Solid Neoplasm, Metastatic Melanoma
- Trial name
- NCT01989585
- Testing
- Biopsy Procedure, Biospecimen Collection, Computed Tomography
- Where
- 49 sites in United States
- Volunteers
- 75 people
- Sponsor
- National Cancer Institute (NCI)
Allergy to Grass Pollen
Biological Standardization of Lolium Perenne Allergen Extract
The objective of this study is to determine the biologic activity of a Lolium perenne allergen extract in histamine equivalent prick (HEP) units, in order to be used as in-house reference preparation (IHRP).
- Trial name
- NCT01394289
- Testing
- Lolium allergen extract
- Where
- 2 sites in Spain
- Volunteers
- 31 people
- Sponsor
- Laboratorios Leti, S.L.
Rheumatoid Arthritis, Fibromyalgia, Secondary
Protocol for a Diagnostic Test Accuracy of Histological Muscle and Skin Biopsies of Rheumatoid Arthritis Patients Revealing Objective Chronic Widespread Pain Phenomena Related to Fibromyalgia
Background: Chronic widespread pain is challenging in the management of the patient with rheumatoid arthritis (RA), affecting approximately one third of this patient population.
- Conditions
- Rheumatoid Arthritis, Fibromyalgia, Secondary, Widespread Chronic Pain, Muscle Disorder
- Trial name
- NCT06305026
- Testing
- Muscle- and skin biopsies
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Menopause, Healthy Female Participants
A Study to Assess the Skin Irritation and Sensitization of Estradiol/Levonorgestrel TDS in Healthy Postmenopausal Subjects
The two products used in this study are transdermal patches that contain selegiline. The test drug is the Estradiol/Levonorgestrel Transdermal Delivery System (TDS). The comparator drug is the Climara Pro® TDS.
- Trial name
- NCT07794150
- Testing
- Estradiol/Levonorgestrel Transdermal System
- Where
- 2 sites in United States, India
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Corium Innovations, Inc.
Triple Negative Breast Cancer, Triple Negative Breast Neoplasms
Image-based AI Predictive Biomarkers for Precision Neoadjuvant Triple-negative Breast Cancer Treatment
Pear Bio has developed an organ-on-a-chip device together with a computer vision pipeline through which the response of an individual patient's tumor to different chemotherapy regimens can be tested simultaneously ex vivo.
- Trial name
- PEAR-TNBC (NCT05435352)
- Testing
- Core needle biopsy
- Where
- 3 sites in United Kingdom
- Volunteers
- 34 people
- Sponsor
- Ourotech, Inc.
Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8
Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors
This phase I trial tests the safety, side effects, and best dose of ZEN003694 when given together with abemaciclib in treating patients with NUT carcinoma, breast cancer or other solid tumors that have spread from where it first…
- Conditions
- Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma, Metastatic Malignant Solid Neoplasm
- Trial name
- NCT05372640
- Testing
- Abemaciclib, BET Bromodomain Inhibitor ZEN-3694, Biopsy Procedure
- Where
- 7 sites in United States
- Volunteers
- 45 people
- Sponsor
- National Cancer Institute (NCI)
Breast Cancer
Effects of a Group Residential Retreat on Cancer Outcomes
The goal of this behavioral research study is to compare 2 different types of residential group programs to help researchers learn if and how well these groups may help to improve physical and emotional well-being in patients…
- Trial name
- NCT02429544
- Testing
- Residential Program, Questionnaires, Electroencephalogram (EEG)
- Sponsor
- M.D. Anderson Cancer Center
Allergy
Virtual Reality During Skin Prick Test
Skin prick testing (SPT) is a cornerstone diagnostic procedure for identifying allergic sensitizations in pediatric patients. Despite being minimally invasive, it often provokes considerable anxiety, fear, and pain, potentially…
- Trial name
- NCT06952192
- Testing
- Virtual reality
- Where
- Italy
- Volunteers
- 108 people
- Sponsor
- Federico II University
Breast Cancer
A Phase II Trial Testing Oral Administration of Lucitanib in Patients With Fibroblast Growth Factor Receptor (FGFR)1-amplified or Non-amplified Estrogen Receptor Positive Metastatic Breast Cancer
The aim of the study is to evaluate the objective response rate (ORR) of single agent lucitanib in metastatic breast cancer patients with FGFR1-amplified, FGFR1-non amplified with 11q amplification, or FGFR1-non amplified without…
- Trial name
- FINESSE (NCT02053636)
- Testing
- lucitanib
- Where
- 29 sites in Australia, Belgium and 7 more
- Volunteers
- 76 people
- Sponsor
- Institut de Recherches Internationales Servier
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