Clinical trials: Skin Tone
Pigmentation, Redness
Photoprotection Efficacy With Sunscreen Formulas Containing the Cyclic Merocyanine Long-UVA Absorber MCE Under Long-UVA Exposure
To evaluate the photo-protector effect of BC_3 (E212657) formulated in SPF compared to SPF alone on long-UVA induced pigmentation in healthy volunteers.
- Trial name
- NCT04865094
- Testing
- cyclic merocyanine
- Where
- Romania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Skin Pigmentation, Healthy Volunteers
Efficacy of Cosmetic Products in Preventing Pigmentation Induced by High Energy Visible Light (HEVL) [400-450nm]
The goal of this double-blind, randomized clinical trial is to evaluate the efficacy of anti-pigmentation cosmetic products in preventing skin pigmentation induced by High Energy Visible Light (HEVL) [400-450nm] in healthy…
- Conditions
- Skin Pigmentation, Healthy Volunteers, Hyperpigmentation
- Trial name
- NCT07537595
- Testing
- Treated and exposed zones (cosmetic topical products applied), Untreated and exposed zone (no product applied)
- Where
- Romania
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Sunscreening Agent
Sun Protection Factor Assay
To evaluate the Sun Protection Factor efficacy on human skin.
- Trial name
- SPF Assay (NCT02822313)
- Testing
- Coppertone (BAY987518)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Bayer
Melanosis
A Pilot Study Testing 1064nm Q-switch Laser Versus Glycolic Acid Peels for the Treatment of Melasma
The purpose of this study is to find out the safety and effectiveness of 1064 Q-Switch Laser Therapy compared to Glycolic Acid Chemical Peels for the treatment of melasma.
- Trial name
- NCT01976273
- Testing
- 1064nm Q-switch Laser, Glycolic Acid Peels
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Stress, Skin Imperfections
Effects Of A Probiotic Formulation On Stress and Skin Health in Younger Adult Females
The goal of this clinical trial is to test to efficacy of a probiotic blend on stress and skin appearance in young females. It is hypothesized that those taking the probiotic blend will have decreased levels of perceived stress…
- Conditions
- Stress, Skin Imperfections, Skin Fine Lines
- Trial name
- Cosmebiome (NCT06057883)
- Testing
- Probiotic
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Sunscreening Agents
Sun Protection Factor Assay (SPF Assay 205/2016)
To evaluate the Sun Protection Factor efficacy on human skin.
- Trial name
- NCT02936557
- Testing
- BAY987521
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Bayer
Visible Light Exposure on Healthy Back Skin
Evaluation of the Photoprotection Efficacy of Three Sunscreen Products Under Visible Light Exposure.
To evaluate the protective effect of three sunscreens products on the pigmentation caused by visible light in comparison to an untreated control zone in healthy volunteers.
- Trial name
- NCT06796205
- Testing
- Treated zones exposed with Visible Light source, Untreated zone exposed with Visible Light source
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Vitiligo, Healthy
The Gut and Skin Microbiome in Vitiligo Disease Progression
Investigators plan to perform a pilot study that aims to characterize the microbiome of human vitiligo patients with both active and stable disease and compare this to the microbiome of age and sex matched controls.
- Trial name
- NCT03577327
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Benign Pigmented Lesions
Picosecond Laser for Ttreatment of Benign Pigmented Lesions
The purpose of this study is to determine whether Pico laser is effective and safe in the treatment of benign pigmented lesions.
- Trial name
- NCT02146820
- Testing
- GentleMax system
- Where
- 2 sites in United States, China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Sun Damaged Skin
Photoprotective Effects of a SPF50+ Sunscreen on Skin Genotoxicity Induced by Repeated Chronic Outdoor Sun Exposure
Between 2 and 3 million non-melanoma skin cancers and 132,000 melanoma skin cancers occur globally each year. Sun protection continues to be a major public health issue and has always been a priority research area for Pierre…
- Trial name
- NCT05926791
- Testing
- Cosmetic product
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Sunscreening Agent
Sun Protection Factor Assay
To evaluate the Sun Protection Factor efficacy on human skin.
- Trial name
- SPF Assay (NCT02822261)
- Testing
- Coppertone (BAY987516)
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Bayer
Real Life Pigmentation
Photoprotection Efficacy With Sunscreen Formulas Containing the Cyclic Merocyanine Long-UVA Absorber MCE, Under Real Sun Exposure
To evaluate the photo-protector effect of BC_3 (E212657) formulated in SPF30 compared to SPF30 alone on real sun exposure induced pigmentation in healthy volunteers
- Trial name
- NCT04865055
- Testing
- cyclic merocyanine
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Sunscreening Agents
Sun Protection Factor Assay (SPF Assay 202/2016)
To evaluate the Sun Protection Factor efficacy on human skin.
- Trial name
- NCT02930785
- Testing
- BAY987517
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Bayer
Vitiligo
Determining the Tolerance of Depigmented Skin to Targeted Phototherapy Using UVB in Patients With Vitiligo
The purpose of this study is to determine if vitiligo patients develop tolerance to ultraviolet light therapy, a type of treatment available for vitiligo.
- Trial name
- NCT00367224
- Testing
- 6 to 9 ultraviolet B treatments, Skin biopsies
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Visible Light Exposure on Healthy Back Skin
Photoprotection Efficacy of Different Topical Agents Under Visible Light Exposure
To evaluate the protective effect of seven sunscreens on the pigmentation induced by visible light in comparison to an untreated control zone in healthy volunteers
- Trial name
- NCT06796153
- Testing
- Visible Light Exposure - Treated zones, Visible Light Exposure - Untreated zone
- Where
- Romania
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Vitiligo
Evaluation of Serum and Tissue Cathepsin L in Non-segmental Vitiligo Patients
Introduction Vitiligo is an autoimmune disease of the skin that targets pigment producing melanocytes and results in patches of depigmentation that are visible as white spots (Frisoli et al., 2020) Vitiligo is a relatively common…
- Trial name
- NCT06261073
- Testing
- blood sample and tissue biopsy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sohag University
Vitiligo
Evaluation of the Efficacy and the Cutaneous Acceptability of a Dermocosmetic Product in the Repigmentation of Vitiligo
Study in proof of concept; Double blind study; Comparative study, versus placebo in intra-individual Three parallel groups testing different dosages / combinations of treatments Randomized.
- Trial name
- NCT04171427
- Testing
- Lithium liposome
- Where
- Tunisia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Laboratoire Dermatologique ACM
Skin Ageing, Skin
Skin Type Determination Using Image Artificial Intelligence
Skin color, how easily a person burns or tans in the sun (skin phototype), and the amount of chronic sun damage in the skin are important factors in skin health.
- Trial name
- SPAI (NCT07765303)
- Testing
- Skin imaging and skin characteristic assessment
- Where
- 13 sites in Australia, Brazil and 9 more
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Region Skane
Vitiligo
T Central Memory Cells in Early Localized Non-Segmental Vitiligo
Assessing the level of circulating TCMs (cluster of differentiation (CD) 8+, CD3+,C- chemokine receptor (CCR)7, cluster of differentiation 45 receptor (CD45R) cells) in early localized vitiligo cases prior to treatment and after…
- Trial name
- NCT05706636
- Testing
- oral mini pulse, Topical cream, targeted phototherapy
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Vitiligo
Stress Response Pathways in Vitiligo
The purpose of this study is to investigate stress response pathways in tissues and melanocytes from patients with vitiligo. Investigators are collecting evidence of UPR and stress response activation in tissues and melanocytes…
- Trial name
- NCT02797574
- Testing
- Punch Biopsy at a Lesional Site, Punch Biopsy at a Non- Lesional site
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health