Clinical trials: Skin Ulcer
Pressure Ulcer
CMAP Refinement for Pressure Injury Prevention
For Veterans with spinal cord injury who use a wheelchair, pressure injuries related to sitting are a significant daily threat to well-being.
- Trial name
- NCT04309864
- Testing
- Use of CMAP app for education (in-hospital), Use of CMAP app (in-home)
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Skin Physiology, Spinal Cord Injuries
Intelligent Underwear (IU) in Paraplegics
Pressure injuries are a major problem in patients with no or limited mobility and sensation such as paraplegics. Changes in skin physiology like changes in skin perfusion, oxygenation and humidity may explain and help to detect…
- Conditions
- Skin Physiology, Spinal Cord Injuries, Pressure Injury
- Trial name
- ProTex (NCT04008160)
- Testing
- ProTex
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Swiss Paraplegic Research, Nottwil
Pressure Ulcer, Pressure Injury
IDEAL SKIIN CARES Bundle to Prevent Pressure Injury
The study will be a multi-center, triple-blinded, cluster randomized controlled trial (c-RCT) conducted with a three-arm parallel design and a 1:1:1 allocation ratio.
- Conditions
- Pressure Ulcer, Pressure Injury, Bed Sore, Pressure Sore
- Trial name
- IdealSkinCares (NCT06369688)
- Testing
- IDEAL SKIIN CARES bundles, IDEAL SKIIN CARES bundles workshop, Respiratory care workshop
- Volunteers
- 1,620 people, healthy volunteers welcome
- Sponsor
- Baqiyatallah Medical Sciences University
Blister, Wound of Skin
Safety, Tolerability, and Pharmacokinetics of Ascending Topical Doses of TCP-25 Applied to Epidermal Suction Blister Wounds, Non-Healing Leg Ulcers and Patients With Dystrophic Epidermolysis Bullosa.
This is a three-part, Phase I, first-in-human study designed to evaluate the safety, tolerability, and potential systemic exposure of multiple topical doses of TCP-25.
- Conditions
- Blister, Wound of Skin, Epidermolysis Bullosa, Varicose Ulcer of Lower Limb
- Trial name
- NCT05378997
- Where
- Sweden
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Xinnate AB
Chronic Diabetic Foot Ulcers
Nu-3 Topical Gel for Treatment of Diabetic Foot Ulcer
A PHASE 2a, MULTI-CENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED DOSE ESCALATING STUDY TO EVALUATE THE SAFETY AND TOLERABILITY OF TOPICALLY APPLIED BISPHOSPHOCIN NU-3 GEL TO CLINICALLY NONINFECTED CHRONIC DIABETIC FOOT…
- Trial name
- NCT05276401
- Testing
- 5% Bisphosphocin Topical Gel, 10% Bisphosphocin Topical Gel
- Where
- 5 sites in United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Lakewood-Amedex Inc
Ulcer
Using of Irradiated Amnion Dressing for the Treatment of Skin Ulcer
To evaluate the using of a commercial product of dried human amniotic membrane sterilized by gamma irradiation for the treatment of skin ulcer.
- Trial name
- NCT03440528
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Egyptian Atomic Energy Authority
Epidermolysis Bullosa, Chronic Skin Ulcer
Uses of Irradiated Human Amniotic Membrane in the Treatment of Dystrophic Epidermolysis Bullosa Patients
To evaluate the effect of human amniotic membrane as a weekly dressing on chronic wounds in Epidermolysis Bullosa (EB) patients.
- Trial name
- NCT03942250
- Testing
- REGE pro dressing
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Egyptian Atomic Energy Authority
Foot Ulcer Chronic, Skin Ulcer Venous Stasis Chronic
Effectiveness of Autologous Platelet Rich Plasma in the Treatment of Chronic Non-Healing Wounds
This investigation plans to initiate the healing of chronic wounds by providing a concentrated platelet and growth factor therapy directly to the wound site by topical delivery.
- Conditions
- Foot Ulcer Chronic, Skin Ulcer Venous Stasis Chronic, Pressure Ulcer
- Trial name
- NCT02307448
- Testing
- Platelet Rich Plasma, Standard of Care
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- ACR Biologics, LLC
Chronic Skin Ulcer, Diabetic Foot
Plasma and Scarring of Diabetic Ulcers
Diabetic foot is defined by World Health Organization as a syndrome in which the presence of neuropathy, ischemia and infection cause tissue damage or ulcers from minor trauma.
- Conditions
- Chronic Skin Ulcer, Diabetic Foot, Plasma Protein; Transport Protein
- Trial name
- NCT04145154
- Testing
- Application of platelet rich plasma in chronic wounds of diabetic origin
- Where
- Mexico
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidad de Guanajuato
Pressure Ulcer, Skin Lesion
Prevention of Skin Damage in the Patient in Prone Position: Development of Education Interventions Based on a Training Needs Assessment Study.
This is study 1 of 3 - of the overall project: The ProneTection Quality Improvement Project. The three aims of this study, study 1 are: 1.
- Conditions
- Pressure Ulcer, Skin Lesion, Acute Respiratory Distress Syndrome
- Trial name
- NCT05238870
- Testing
- Interviews for the needs analysis. No intervention.
- Where
- 2 sites in Belgium
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Ghent
Xerosis Cutis, Dry Skin
Enhancing SKIN Health and Safety in Aged CARE
Aged long-term care receivers are affected by various adverse skin conditions like pressure ulcers, incontinence-associated dermatitis, dryness, intertrigo and many more.
- Conditions
- Xerosis Cutis, Dry Skin, Pruritus, Pressure Ulcer
- Trial name
- SKINCARE (NCT03824886)
- Testing
- Implementation of skin care algorithm
- Where
- 2 sites in Germany
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- PD Dr. Jan Kottner
Pressure Ulcer
Preventing Pressure Ulcers With Repositioning Frequency and Precipitating Factors
The purpose of this study is to determine whether repositioning frequency can be extended for nursing home (NH) residents who are low, moderate, and high risk for pressure ulcer (PrU) development.
- Trial name
- NCT02996331
- Testing
- 2 hour repositioning, 3 hour repositioning, 4 hour repositioning
- Where
- United States
- Volunteers
- 2,113 people, healthy volunteers welcome
- Sponsor
- Duke University
Ulcer, Skin Ulcer
Epidermal Grafting in Wound Healing
Split thickness skin grafting is the normal standard of care for wound closure. However, this is an invasive procedure and associated with pain also there can be additional donor site morbidity.
- Conditions
- Ulcer, Skin Ulcer, Wounds and Injuries
- Trial name
- EPIGRAAFT (NCT02535481)
- Testing
- Epidermal grafting, Split thickness skin grafting
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University College, London
Ulcer Foot, Chronic Skin Ulcer
Platelet Rich Plasma (PRP) Bio Stimulant Gel Dressing in Treating Chronic Non Healing Leg and Foot Ulcers: Cost and Effectiveness
Background Chronic non-healing ulcer is a common problem met in clinical practice and represents a burden to the patients. Chronic ulcer lacks growth factors (GFs) to promote the healing process and is frequently followed by…
- Conditions
- Ulcer Foot, Chronic Skin Ulcer, Non-Healing Ulcer of Skin
- Trial name
- NCT04065594
- Testing
- PRP dressing, conventional ordinary dressing
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Acne, Actinic Keratosis
Potential Research Study Participant Registry
The purpose of the potential research study participant registry is to keep potential research subjects informed about any future research studies in which they may meet the criteria for enrollment.
- Conditions
- Acne, Actinic Keratosis, Dysplastic Nevi, Eczema
- Trial name
- NCT00710489
- Where
- United States
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Difficult to Healing of Skin Ulcers
UC-MSCs Gel Treatment Difficult Healing of Skin Ulcers
This study for a six-month trials, Randomized, open, and parallel comparison before and after its own, Stage test includes screening stage, treatment period and follow-up period.
- Trial name
- UC-MSCs (NCT02685722)
- Testing
- UC-MSCs Gel group, Gel group
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Non-pressure Chronic Ulcer of Skin, Not Elsewhere Classified
To Study the Effect of Organic Light Emitting Diodes (OLED) on Cultured Fibroblast
Chronic ulcers is a common clinical problem. Diabetes or peripheral vascular occlusion is major reason leading to chronic wound healing.
- Trial name
- NCT01724710
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Healthy, Skin Ulcer
Pathophysiology of Chronic Wounds
This study will compare blood from healthy volunteers and with wound fluid and tissue samples from patients with acute and chronic wounds enrolled in other NIH studies.
- Trial name
- NCT00006437
- Where
- United States
- Volunteers
- 999 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)