Clinical trials: Skin Ulcer Venous Stasis Chronic
Venous Ulcer, Pressure Ulcer
Safety and Efficacy of the Fruit-based Product OPAL A for the Treatment of Chronic Venous and Pressure Ulcers
The purpose of this study is to examine the safety and efficacy of the fruit-based product OPAL A for the treatment of chronic venous and pressure ulcers.
- Trial name
- NCT00933348
- Testing
- OPAL A
- Where
- Australia
- Volunteers
- 30 people
- Sponsor
- Phoenix Eagle Company
Venous Ulcers
Effect of Hyaluronic Acid ECM on Venous Ulcers
The purpose of this pilot study is to compare the incidence and rate of wound healing in subjects with venous ulcers treated with an extracellular matrix composed of hyaluronic acid plus compression therapy as compared to…
- Trial name
- NCT02930499
- Testing
- Hyalomatrix extra-cellular matrix, Mepilex wound dressing
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Calvary Hospital, Bronx, NY
Chronic Wounds, Diabetic Foot Ulcer
Subcutaneous Dexpanthenol Administration and Wound Epithelialization
Chronic wounds are wounds that do not heal properly over time and can significantly reduce quality of life. Common types include diabetic foot ulcers, venous leg ulcers, and arterial ulcers.
- Conditions
- Chronic Wounds, Diabetic Foot Ulcer, Venous Leg Ulcers, Arterial Ulcer
- Trial name
- DEXPAN-WOUND (NCT07395674)
- Testing
- Dexpanthenol, Standard Wound Care
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Dilara CANBAY OZDEMIR
Venous Leg Ulcer, Chronic Non-Healing Cutaneous Wounds
LUT017 Gel for Venous Leg Ulcers and Chronic Non-Healing Skin Wounds in Adults
This research study is investigating a new topical medication called LUT017, which is being developed to help heal chronic skin wounds, particularly those known as venous leg ulcers (VLUs).
- Conditions
- Venous Leg Ulcer, Chronic Non-Healing Cutaneous Wounds, VLU
- Trial name
- NCT07463365
- Testing
- LUT017 gel
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Antoni Ribas
Skin Ulcer
Bio-ConneKt Wound Dressing for Treatment of Chronic Leg Wounds: A Pilot Study
The purpose of this study is to assess the performance of the bio-ConneKt™ wound dressing and compare its performance with the standard of care at NFRMC Wound Therapy Services, for the treatment of chronic foot/leg ulcers…
- Trial name
- NCT02309684
- Volunteers
- 20 people
- Sponsor
- MLM Biologics Inc.,
Venous Insufficiency
Non-Invasive Management of Chronic Venous Insufficiency
The purpose of this study is: -item one to use two new non-invasive technologies to evaluate scarring and swelling associated with chronic venous insufficiency.
- Trial name
- NCT00950378
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Utah
Varicose Ulcer
Autologous Skin Substitute for Chronic Leg/Foot Ulcers.
A prospective, multicenter, randomised controlled phase II study in which patients with therapy resistant (arterio-) venous leg/foot ulcers are treated with Tiscover® (test group) or with AS210 (control group) to determine the…
- Trial name
- NCT02360358
- Testing
- Tiscover, AS210
- Where
- 5 sites in Netherlands
- Volunteers
- 8 people
- Sponsor
- Chantal Blok
Ulcer, Venous Ulcer
ECM and Blood Components for Wound Healing
The Extracellular Matrix (ECM) and Blood Components for Wound Healing feasibility study is a clinical trial approved by Health Canada to study the safety of extracellular matrix (ECM) and autologous blood products in wound…
- Conditions
- Ulcer, Venous Ulcer, Foot Ulcer, Diabetic
- Trial name
- NCT01909908
- Testing
- ECM, Blood Products, ECM in Blood Products
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Cook Group Incorporated
Diabetic Foot Ulcer, Venous Leg Ulcer
The Avelle® Negative Pressure Wound Therapy System on Chronic Wounds
This study seeks to demonstrate the performance of Negative Pressure Wound Therapy on chronic wounds such as diabetic foot ulcers and venous leg ulcers.
- Trial name
- SPACE (NCT05666570)
- Testing
- Avelle NPWT
- Where
- Colombia
- Sponsor
- ConvaTec Inc.
Ulcers, Wound - in Medical Care
Study on the Effectiveness of Hypothermal Sulphurous Water in Wound Hygiene
This is an interventional double arms pilot study on the effectiveness of hydrogen sulfide (H2S) rich and microbiologically pure spa sulphurous water, in the wound hygiene of hard-to heal wounds, set in an italian spa facility.
- Conditions
- Ulcers, Wound - in Medical Care, Wounds and Injuries, Wound Healing
- Trial name
- NCT06725797
- Testing
- wound hygiene with hypothermal sulfurous water by packs, wound hygiene with hypothermal sulfurous water by limb full immersion
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Roma La Sapienza
Venous Ulcer
Effectiveness of XCell on Autolytic Debridement of Venous Ulcers
This clinical trial is designed to evaluate the effect of XCell cellulose wound dressing for its ability to naturally (autolytically) remove nonviable tissue and create a healthy vascular wound bed.
- Trial name
- XCell (NCT00446823)
- Testing
- XCell cellulose wound dressing, Impregnated gauze dressing
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Xylos Corporation
Chronic Venous Disease
Surface NeuroMuscular Electrical Stimulation in the Treatment of Chronic Venous Leg Ulcers
This study aims to determine if the use of surface neuromuscular electrical stimulation, applied to various motor points on the lower limb to elicit muscle contraction when combined with compression bandaging accelerates the rate…
- Trial name
- NCT01801891
- Testing
- VASGARD stimulator, Compression bandaging
- Where
- 2 sites in Ireland
- Volunteers
- 25 people
- Sponsor
- Professor Stewart Walsh
Non-healing Wound
Treatment of Wounds Using Oasis® ECM
The purpose of this clinical study is to gather post-market clinical evidence on the use of Oasis ECM as a treatment for donor site wounds in the community setting in the United Kingdom.
- Trial name
- NCT03632031
- Testing
- Oasis Extracellular Matrix, Standard Care (in control arm)
- Where
- 2 sites in United Kingdom
- Volunteers
- 41 people
- Sponsor
- Cook Biotech Incorporated
Venous Ulcer
Preliminary Testing of New Treatment for Chronic Leg Wounds
The primary objectives of this study are to evaluate the efficacy, dosing, and safety of an intra-ulcer injection H5.020CMV.PDGF-b in adults who have a venous leg ulcer.
- Trial name
- NCT01858272
- Testing
- H5.020CMV.PDGF-b and limb compression bandage
- Volunteers
- 15 people
- Sponsor
- University of Pennsylvania
Venous Leg Ulcer
Evaluating the Efficacy of NeoThelium FT in the Treatment of Venous Leg Ulcers
This is a randomized controlled trial evaluating the efficacy of NeoThelium FT in conjunction with standard of care vs. standard of care alone in treating venous leg ulcers.
- Trial name
- NCT06930768
- Testing
- Standard of Care, NeoThelium FT
- Volunteers
- 132 people
- Sponsor
- NuScience Medical Biologics, LLC
Ulcer Venous, Wound Heal
Observational Study to Investigate the Use of Sterilized Porcine Placental Tissue in the Treatment of Chronic VLU
The study is a multi-center, prospective, clinical trial designed to evaluate the use of InnovaMatrix AC sterilized porcine placental ECM to treat chronic VLUs .
- Trial name
- NCT06400875
- Testing
- InnovaMatrix® AC Sterilized, Porcine Placental Extracellular Matrix (ECM)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- ConvaTec Inc.
Varicose Ulcer
Vein Fitness System vs Compressive Therapy for Venous Ulcers: a Bayesian Adaptive Trial
The objective of this Bayesian Adaptive trial is to compare a control group versus a comprehensive ulcer healing protocol. The latter involves a combination of compressive therapy, miokinetic drainage and muscle strengthening for…
- Trial name
- NCT03127904
- Testing
- Vein Fitness, Compressive therapy and wound care
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Pró Circulação®
Varicose Ulcer
MIST Ultrasound Therapy Compared to United Kingdom Standard Care for the Treatment of Non-healing Venous Leg Ulcers
Chronic venous leg ulcers (VLUs) impact negatively on patients' quality of life. Standard treatment in the UK for patients with VLUs is compression bandaging or stockings.
- Trial name
- NCT01671748
- Testing
- MIST ultrasound therapy, Standard Care
- Where
- United Kingdom
- Volunteers
- 47 people
- Sponsor
- Cardiff and Vale University Health Board
Venous Leg Ulcer
Clinical Study Of Affinity Versus SOC In The Management Of VLUs
This prospective, multi-center, randomized, controlled clinical study compares Affinity® plus SOC to SOC alone in subjects with VLUs.
- Trial name
- NCT04901013
- Testing
- Affinity
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Organogenesis
Venous Leg Ulcer
Pivotal Trial of Dermagraft(R) to Treat Venous Leg Ulcers
This study randomly assigns patients with venous leg ulcers to receive standard therapy (compression) alone or compression plus Dermagraft(R).
- Trial name
- DEVO (NCT00909870)
- Testing
- Dermagraft(R), Profore
- Where
- 70 sites in United States, Austria and 6 more
- Volunteers
- 537 people
- Sponsor
- Organogenesis