Clinical trials: Skin Wrinkling
Hair Loss/Baldness, Wrinkle Appearance
Autologous Adipose Cells Therapy
Autologous Adipose Cell Therapy is a series of process designated to address the demerits of the traditional autologous fat grafting and dermal fillers, while enhancing the versatility and aesthetic outcomes.
- Conditions
- Hair Loss/Baldness, Wrinkle Appearance, Volume, Fine Lines
- Trial name
- NCT06869252
- Testing
- Autologous Adipose Cells Therapy
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- CERM INC.
Wrinkle, Pigmentation
Device for Improving Skin Quality and Texture on the Face and Neck
The goal of this clinical trial is to investigate the effect of the BTL-785F device (with BTL-785-4-4 tip on BTL-785-4 applicator) on the improvement of skin quality and texture on the face and neck in healthy adult volunteers.
- Conditions
- Wrinkle, Pigmentation, Skin Laxity, Skin Scarring
- Trial name
- NCT06645366
- Testing
- Treatment with BTL-785F
- Where
- 3 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Skin Aging of Face and Hands, Facial Wrinkles - Rough Texture - Hyperpigmentation
DMAE Oleate for Facial Skin Firmness and Fine Lines in Healthy Adults
This single-arm, cosmetic study will evaluate the efficacy of topical DMAE Oleate on facial skin firmness and lines/wrinkles in healthy adults.
- Conditions
- Skin Aging of Face and Hands, Facial Wrinkles - Rough Texture - Hyperpigmentation, Skin Laxity
- Trial name
- NCT07255560
- Testing
- Topical DMAE Oleate
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bionos Biotech S.L.
Skin Laxity, Wrinkles
A Retrospective Study to Evaluate the Effectiveness of the Ulthera System
Up to 120 subjects within the study site's practice who have already had an Ultherapy™ treatment to the face and neck will be enrolled to monitor treatment effectiveness.
- Trial name
- NCT01519934
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc
Aging
Investigation of a Novel Cosmeceutical to Reduce the Visible Signs of Cutaneous Aging
Tomorrowlabs has developed a revolutionary cosmeceutical formulation to rejuvenate aging skin. Tomorrowlabs is conducting this research to study whether this cosmeceutical can reduce the visible signs of cutaneous aging.
- Trial name
- REDUCEAGE (NCT02877758)
- Testing
- Tomorrowlabs cosmeceutical formulation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tomorrowlabs GmbH
Improvement of Wrinkles/Elastosis and/or Pigmentation
Impact of M22 Synergistic Sequential Treatment (SST)
Up to 40 healthy subjects at 2 sites, age 30-65 year old with Fitzpatrick-Elastosis score of 3-6 and mild to moderate age/sun-related facial pigmentation that wish to improve their facial skin appearance.
- Trial name
- NCT02032771
- Testing
- M22 IPL and ResurFX
- Where
- 2 sites in United States, Germany
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Wrinkle Reduction
Assessment of the Safety and Effectiveness of a Micro-RF Skin Treatment Device (nebulyft）
The objective of the study is to evaluate the safety, efficacy and usage compliance of the home-use device nebulyft for self-treatment of wrinkles appearance. The participants do treatment 5 time /week and last 4 weeks.
- Trial name
- ASEMRSTD (NCT06623214)
- Testing
- nebulyft
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Hangzhou Rebecca Medical Science and Technology Ltd.
Skin Laxity, Wrinkle
Evaluation of Efficacy and Safety of the triLift™ System
Single center, single-arm, prospective, open Label with Before \& After Study Design.
- Trial name
- LUM-triLift (NCT05773924)
- Testing
- triLift system
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Intrinsic Aging of Skin, Skin Wrinkling
Study of Intradermal Injections of RCS-01 in Male and Female Subjects
The primary purpose of this study is to assess the safety profile of RCS-01 injections as compared to placebo injections. This study will also measure the impact these injections will have on skin markers related to aging through…
- Conditions
- Intrinsic Aging of Skin, Skin Wrinkling, Solar Degeneration of Skin
- Trial name
- NCT02391935
- Testing
- RCS-01
- Where
- Germany
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- RepliCel Life Sciences, Inc.
Wrinkles, Striae
Clinical Evaluation of M22 ResurFX 1565nm Module
At least thirty (30) subjects, Fitzpatrick-Goldman Skin Type I-IV will be enrolled in 2 clinical sites; each clinic will enroll at least 15 subjects. Subjects should present visible wrinkles and/or striae requiring treatment.
- Trial name
- NCT01796626
- Testing
- M22 ResurFX module
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Laxity; Skin
Pivotal Study to Evaluate the Safety and Efficacy of a Micro-coring Device Treating Moderate to Severe Facial Wrinkles
Study evaluating the safety and efficacy of a micro-coring device for the treatment of moderate to severe cheek wrinkles.
- Trial name
- NCT03573271
- Testing
- MCD
- Where
- 5 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cytrellis Biosystems, Inc.
Skin Laxity, Wrinkle
Safety and Efficacy of SofWave Treatment to Lift Lax Tissue in the Submental and Neck Zones and to Lift the Eyebrow
This is a prospective, open label, multi-center, self-controlled clinical study to demonstrate the safety and efficacy of SofWave treatment to lift lax tissue in the submental and neck zones and to lift the eyebrow.
- Conditions
- Skin Laxity, Wrinkle, Brow Lifting
- Trial name
- NCT04146584
- Testing
- Sofwave Treatments
- Where
- 5 sites in United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Sofwave Medical LTD
Wrinkle
Robotic Mechanical Coring for the Treatment of Moderate to Severe Facial Wrinkles
This study is a prospective, up to 4 center study of the safety and efficacy of mechanical coring with skin closure of cored holes, intended for the improvement in the appearance of wrinkles of the cheeks in up to 70 subjects…
- Trial name
- NCT05091788
- Testing
- Venus Aime
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Photoaging, Hyperpigmentation
Randomized, Double-Blind Evaluation of Maple Leaf Extract (Maplifa) for Photoaging
Recent research has reported that the maple leaf extract exhibits anti-aging effects by inhibiting elastase activity, thereby preventing the breakdown of elastin and interfering with the formation of wrinkles.
- Conditions
- Photoaging, Hyperpigmentation, Rhytides
- Trial name
- NCT04586816
- Testing
- 1% red maple leaf extract in cream base, 5% red maple leaf extract, vehicle
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Wrinkles
Silk'n HST for Wrinkle Reduction - Clinical Study Protocol
The objective of the study is to evaluate the safety, efficacy and usage compliance of the home-use device Silk'n HST for self-treatment of periorbital wrinkles and skin laxity and improvement of skin appearance.
- Trial name
- NCT02913547
- Testing
- Silk'n HST
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Home Skinovations Ltd.
Spot Pigmented, Wrinkle
Clinical Study for the Efficacy Evaluation of a Food Supplement
The primary aim of this in vivo clinical study is to evaluate the depigmenting effect of an active ingredient incorporated into a food supplement through the evaluation of the melanin variation parameter, assessed with the…
- Trial name
- NCT06453837
- Testing
- Mentha Suaveolens extract incorporated into a food supplement
- Where
- Portugal
- Volunteers
- 110 people
- Sponsor
- Mibelle Group Biochemistry
Periorbital Hyperpigmentation, Periorbital Edema
A 12 Week Study to Evaluate the Efficacy of an Eye Cream
This single center, open-label clinical study was conducted to assess the efficacy and tolerance of a topical eye cream when used over the course of 12 weeks by healthy women with moderate to severe under-eye dark circles…
- Conditions
- Periorbital Hyperpigmentation, Periorbital Edema, Fine Lines, Wrinkle
- Trial name
- NCT05807620
- Testing
- Gentle Cleansing Lotion, Facial Moisturizer, Sunscreen SPF 30
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Collagen Degeneration, Wrinkle
The Effects of Almond on Facial Skin Collagen and Wrinkles
Investigate the effects of almond consumption on collagen production, elastin levels, wrinkles, and pigmentation among premenopausal women and postmenopausal women belonging to all Fitzpatrick skin types.
- Conditions
- Collagen Degeneration, Wrinkle, Pigmentation, Elastic Skin
- Trial name
- NCT06074276
- Testing
- Food: whole almonds, Food: non-nut snack
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Wrinkles, Rhytids
Evaluation of the Ulthera® System for Treatment of the Face and Neck
Up to 15 subjects will be enrolled. Enrolled subjects will receive one Ulthera® treatment on the face and neck. Follow-up visits will occur at 45, 90 and 180 days post-treatment.
- Conditions
- Wrinkles, Rhytids, Skin Laxity
- Trial name
- NCT01713907
- Testing
- Ulthera® Treatment
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc
Skin Aging, Skin Hydration
A Clinical Trial to Evaluate the Effects of Naila's Collagen Marine Plus Food Supplement on Skin Hydration, Elasticity, Fine Lines and Wrinkles, and Hair and Nail Health
This is a single-group, open-label, virtual (decentralized) clinical trial evaluating the effects of Naila's Collagen Marine Plus Food Supplement on skin hydration, elasticity, firmness, fine lines and wrinkles, and hair and nail…
- Conditions
- Skin Aging, Skin Hydration, Skin Elasticity, Fine Lines and Wrinkles
- Trial name
- NCT07746076
- Testing
- Naila's Collagen Marine Plus Food Supplement
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gulf Bird