Clinical trials: Skull
Thyroid Cancer, Recurrent Laryngeal Nerve Injuries
Effect of Reversed Tracking Method for Identification of EBSLN in Thyroid Surgery
The feasibility and effectiveness of Reversed Tracking Method for the identification and protection of extralaryngeal nerve branches in thyroid surgery were analyzed.
- Trial name
- NCT03680222
- Testing
- Reversed Tracking Method
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fujian Medical University
Vestibular Schwannoma, Unilateral Vestibular Deficit
Mapping of Vestibular Centers Activation Using fMRI in Patients With Vestibular Schwannoma
The goal of this clinical trial is to visualize the possible activation of vestibular centers in the brain using in patiens with unilateral vestibular damage, specifically in patients after vestibular schwannoma surgery.
- Conditions
- Vestibular Schwannoma, Unilateral Vestibular Deficit, Healthy
- Trial name
- NCT07130851
- Testing
- vestibular schwannoma resection
- Where
- Czechia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marketa Bonaventurova
Hemodynamic Response, Skull Pins Application
Comparison of Dexmedetomidine and Fentanyl to Prevent Hemodynamic Response to Skull Pins Application
To compare the effect between dexmedetomidine and fentanyl for controlling the hemodynamic response to skull pins application
- Trial name
- NCT03077503
- Testing
- Dexmedetomidine, Fentanyl, 0.9% normal saline
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Khon Kaen University
Head Trauma, Craniocerebral Injuries
Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas
The goal of this study is to determine the sensitivity, specificity, and positive and negative predictive values of the a portable near-infrared-based device (portable NIR-based device), the InfraScanner 2000™, to detect…
- Conditions
- Head Trauma, Craniocerebral Injuries, Crushing Skull Injury, Head Injuries
- Trial name
- NCT03353246
- Testing
- InfraScanner 2000™
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Duke University
Trigeminal Neuralgia
Pathophysiological Mechanisms of Trigeminal Neuralgia - Neurophysiological Assessment of the Blink-reflex
This study aims to increase the understanding of the pathophysiology of trigeminal neuralgia by investigating the potential association between blink reflex abnormalities and phenotypical traits e.g.
- Trial name
- TNBR (NCT05328661)
- Testing
- Blink reflex
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Danish Headache Center
Amblyopia, Anisometropia
Dichoptic Virtual Reality Therapy for Amblyopia in Adults
This was a randomized, masked, controlled study of the effect of a virtual reality, binocular, 3-dimensional video game on visual acuity and stereopsis in adult patients with amblyopia.
- Conditions
- Amblyopia, Anisometropia, Strabismus
- Trial name
- NCT02246556
- Testing
- Dichoptic therapy, Patching therapy, Dioptic (non-dichoptic) therapy
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of California, San Francisco
Childhood Atypical Teratoid/Rhabdoid Tumor, Childhood Central Nervous System Germ Cell Tumor
Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors
This phase I trial is studying the side effects and best dose of lenalidomide in treating young patients with recurrent, progressive, or refractory CNS tumors.
- Conditions
- Childhood Atypical Teratoid/Rhabdoid Tumor, Childhood Central Nervous System Germ Cell Tumor, Childhood Choroid Plexus Tumor, Childhood Craniopharyngioma
- Trial name
- NCT00100880
- Testing
- lenalidomide, perfusion-weighted magnetic resonance imaging, diffusion-weighted magnetic resonance imaging
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- National Cancer Institute (NCI)
Facial Nerve Palsy
The Role of a Device to Evaluate the Neuromuscular Function in Assessing Muscle in Facial Paralysis Patients
The objective of the research is to determine whether the MyotonPRO has a valid and reliable application in facial, head and neck surgery. In addition, the study aims to compare this new technology with current electromyography.
- Trial name
- MyotonPRO (NCT02489162)
- Testing
- MyotonPRO, non-invasive electromyography (EMG)
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Neurofibromatosis Type II, NF2
Study to Determine Optimal Dose, Evaluate the Efficacy and Safety of PRG-N-01 in Patients With Neurofibromatosis Type II
The goal of this clinical trial is to learn if Trineumin(Code name:PRG-N-01) works to treat Neurofibromatosis Type II(NF2) in adults. It will also learn about the safety and tolerability and toxicity of PRG-N-01.
- Trial name
- NCT07131722
- Testing
- Trineumin
- Volunteers
- 25 people
- Sponsor
- PRG Science & Technology Co., Ltd.
Post-Thyroidectomy Dysphonia
Effects of Therapeutic Exercise With and Without Nerve Stimulation on Dysphonia in Post Thyroidectomy Patients
This clinical trial evaluates rehabilitation strategies for post-thyroidectomy dysphonia. Voice impairment is a frequent complication following thyroid surgery. It often occurs even without direct laryngeal nerve transection.
- Trial name
- NCT07811154
- Testing
- therapeutic exercise, therapeutic exercise + transcutaneous nerve stimulation
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Neuromyelitis Optica Spectrum Disorders
A Clinical Study of B001 Injection in the Treatment of Neuromyelitis Optica Spectrum Disorders(NMOSD)
To evaluate the efficacy and safety of B001 injection in aquaporin-4 antibody positive patients with neuromyelitis optica spectrum disorder.
- Trial name
- NCT06413654
- Testing
- B001
- Where
- 51 sites in China
- Volunteers
- 132 people
- Sponsor
- Shanghai Jiaolian Drug Research and Development Co., Ltd
Optic Neuropathy
Biomechanics of Optic Neuropathy
The participant is being asked to be a subject in this research study because the participant may have a disorder that can cause optic nerve damage and impairment of his/her visual function which is called optic neuropathies…
- Trial name
- NCT02982499
- Testing
- magnetic resonance image (MRI), Optical Coherence Tomography (OCT)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Miami
Chondrosarcoma
Proton Beam Therapy for Chondrosarcoma
The goal of this clinical research study is to learn if proton beam therapy, with or without photon beam radiation therapy, is effective in the treatment of skull base chondrosarcoma.
- Trial name
- NCT00496522
- Testing
- Proton Beam Therapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- M.D. Anderson Cancer Center
Strabismus
Lees Screen in Concomitant Strabismus
Preoperative and postoperative Lees screen was done after concomitant horizontal strabismus surgery to detect any limitation in the field of operated muscle
- Trial name
- NCT04213053
- Testing
- strabismus surgery
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Minia University
Pain, Procedural
ANI and Remifentanil in Skull Pin Fixation.
Forty patients were enrolled, and all patients used total intravenous anesthesia (remifentanil-propofol based total intravenous analgesia) as anesthesia induction and maintenance.
- Trial name
- NCT05125328
- Testing
- Remifentanil
- Where
- Taiwan
- Volunteers
- 27 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Neuromyelitis Optica (NMO), Neuromyelitis Optica Spectrum Disorders (NMOSD)
Slow vs. Rapid Glucocorticoids Tapering With Inebilizumab in NMOSD
Neuromyelitis optica spectrum disorder (NMOSD) is a central nervous system autoimmune condition mainly involving the spinal cord, optic nerves, and area postrema.
- Trial name
- STARGlu-NMO (NCT07132398)
- Testing
- Slow-tapering glucocorticoids + Inebilizumab, Rapid-tapering glucocorticoids + Inebilizumab
- Volunteers
- 170 people
- Sponsor
- Tianjin Medical University General Hospital
Asthenopia, Contact Lenses
Connecting Contact Lenses and Digital Technology
This study seeks to address whether or not different types of daily disposable soft contact lenses may be a beneficial option for patients complaining of eye strain and visual discomfort while using digital devices.
- Conditions
- Asthenopia, Contact Lenses, Ocular Accommodation, Convergence, Excess
- Trial name
- NCT02921087
- Testing
- Test Daily Disposable Soft Contact Lenses, Control Daily Disposable Soft Contact Lenses
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Trigeminal Neuralgia
Analgesic Effect of Ultrasound Guided Maxillary Nerve Block in Trigeminal Neuralgia
This is a study about the dynamics and effects of ultrasound guided maxillary nerve block in trigeminal neuralgia
- Trial name
- NCT06129071
- Testing
- US guided block of maxillary nerve
- Where
- Croatia
- Sponsor
- Varazdin General Hospital
Bell Palsy
EFFECTİVENESS OF PULSED ULTRASOUND TREATMENT ON PATIENTS WITH BELL'S PALSY
Bell's palsy (idiopathic facial palsy) is the most common peripheral lesion of the cranial nerves and the most common mono-neuropathy.
- Trial name
- NCT04412733
- Testing
- Therapeutic Pulsed Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Trigeminal Neuralgia (TN), Orofacial Pain
Identification of Possible Trigeminal Neuralgia
Trigeminal neuralgia (TN) is a severe type of non-dental orofacial pain that can feel like sudden electric shocks in the face and is often mistaken for tooth pain or other dental problems.
- Conditions
- Trigeminal Neuralgia (TN), Orofacial Pain, Dental Pain, Questionnaire
- Trial name
- IDTN (NCT07453511)
- Testing
- Completion of the IDTN Questionnaire
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- University College, London
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