Clinical trials: Sleep
Parkinson Disease, REM Sleep Behavior Disorder
Implementing a National Biobank of PD With WGS and Functional Assessment of Polygenic Inheritance by iPSC Technology
The genetic complexity and heterogeneity of the sporadic forms of Parkinson's disease (PD) are posing a formidable challenge to disentangle their direct molecular causes.
- Trial name
- NCT05721911
- Testing
- whole genome sequencing
- Where
- Italy
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Vasospastic Syndrome
Registration of Skin-Temperatures and Sleep-Wake Behaviour
We study the skin-temperature (skin temperature measurement on different skin regions) and circadian rest-activity cycles (wrist activity monitoring) of 40 women in their daily life.
- Trial name
- NCT00319371
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Sleep Apnea, Temporo-central Epilepsy
Sleep and Memory in Children
Sleep exerts a dual effect on learning: on the one hand, good sleep quality allows good daytime aptitudes leading to knowledge acquisition. On the other hand, sleep after learning is necessary for knowledge consolidation.
- Conditions
- Sleep Apnea, Temporo-central Epilepsy, Narcolepsy, High Intellectual Potential
- Trial name
- EnSOM (NCT02785328)
- Testing
- memory evaluation at V1 and V2 (with treatment), memory evaluation at V1 (without treatment), memory evaluation at V1 and V2 (without treatment)
- Where
- France
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Apnea, Sleep
Remifentanil in Adults With OSA
Obstructive Sleep Apnea (OSA) is the most common problem that affects sleep. People with this problem have their airway blocked or minimized, causing snoring or gasping while sleeping.
- Trial name
- AROSA (NCT02898792)
- Testing
- Targeted infusion of remifentanil
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Sleep, Pregnancy
Halifax PrenaBelt Trial
Back and right-sided sleeping position in pregnant women has recently emerged as a potential risk factor for low birthweight (LBW) and stillbirth (SB) in the medical literature.
- Conditions
- Sleep, Pregnancy, Stillbirth, Infant, Low Birth Weight
- Trial name
- NCT02377817
- Testing
- PrenaBelt
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Allan Kember
Sleep
Kavalactones on Sleep and Cortisol in Healthy Special Forces Trainees
This research study is being done to better understand the effects of kava supplementation on sleep quality and salivary cortisol in the context of the acute physical and psychological stress of military special forces…
- Trial name
- NCT05381025
- Testing
- Kava (Piper methysticum) extract
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Thorne HealthTech, Inc
Breathing-Related Sleep Disorder, Sleep Disorder (Disorder)
Wearable Technology in the Detection and Evaluation of Sleep-Related Breathing Disorders
This project is an observational study that aims to evaluate the accuracy of wearable devices in detecting potential sleep-related breathing disorders (SRBD) in individuals visiting the Sleep-Related Breathing Disorders and Home…
- Trial name
- ReSTech (NCT06606691)
- Testing
- Xiaomi Mi Smart Band 8
- Where
- 2 sites in Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidade da Coruña
Circadian Rhythm Sleep Disorder of Shift Work Type, Metabolic Disease
Impact of Circulating and Tissue-specific Lipids on Vascular Function and Insulin Sensitivity in Chronic Night Shift Workers
People who experience repeated bouts of circadian misalignment, such as shift workers, are at higher risk of cardiovascular disease (CVD) and Type 2 diabetes (T2D) compared to daytime workers.
- Conditions
- Circadian Rhythm Sleep Disorder of Shift Work Type, Metabolic Disease, Insulin Sensitivity, Blood Pressure
- Trial name
- SHINE (NCT06550115)
- Testing
- Time-restricted eating, Control eating
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Obstructive Sleep Apnea
Exercise Intolerance in Obstructive Sleep Apnea Syndrome Patients
The syndrome of obstructive sleep apnea (OSAS) is a public health problem that affects 2 to 4% of the general population. The patients with OSAS frequently complain of intolerance to exercise muscle fatigue and a significant even…
- Trial name
- EXAOS (NCT00837018)
- Testing
- physical exercise program
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Ehler's Danlos Syndrome, Obstructive Sleep Apnea
Obstructive Sleep Apnoea in Children and Adolescents With Ehlers-Danlos Syndrome
Ehlers-Danlos Syndrome (EDS) is a clinically and genetically heterogeneous group of inherited connective tissue disorders characterized by joint hypermobility, skin hyperextensibility, and tissue fragility.
- Trial name
- NCT02712060
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Dementia Caregiver
Dementia Family Caregiver Study
The proposed study will test a 3-month, community health worker (CHW) delivered home visit, culturally and language-appropriate intervention for ethnic and underserved dementia family caregivers of persons with dementia (PWD)…
- Trial name
- NCT04894006
- Testing
- Community Health Worker (CHW) Home Visit Intervention, Attention Control Group with WIoT Technology, Usual Care
- Where
- United States
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Sleep Disorders
Sleep Length and Circadian Regulation in Humans
This research will examine why sleep restriction reduces the body clock's response to bright light. The results will enable the optimization of the bright light treatment of people who suffer from circadian rhythm sleep…
- Trial name
- HAM (NCT00843843)
- Testing
- Bright light box
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Sleep, Diabetes
Individual Differences in Diabetes Risk: Role of Sleep Disturbances
The hypothesis for this study is that some individuals may be at much higher risk to develop type 2 diabetes and that the individual diabetes risk will be predicted by the individual level of slow wave sleep activity (SWA).
- Trial name
- NCT00989976
- Testing
- normal sleep times, bedtime restriction
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Cancer, Depression
Collaborative Care Intervention for Cancer Patients and Their Family Caregivers -LITE
To test the efficacy of a web-based stepped collaborative care intervention to reduce symptoms of depression, pain, and fatigue and improve health-related quality of life (HRQL) in advanced cancer patients and to reduce stress…
- Conditions
- Cancer, Depression, Fatigue, Pain
- Trial name
- CARES-Lite (NCT05601206)
- Testing
- Stepped collaborative care intervention, Enhanced Usual Care
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Obstructive Sleep Apnea
Field Usability Study of Eclipse Mask
The study is designed to assess the usability of a novel CPAP human interface compared to a traditional nasal mask. Human subjects will interact with two different CPAP interfaces including a traditional CPAP mask and the 2nd…
- Trial name
- NCT05559047
- Testing
- Eclipse mask
- Where
- 3 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bleep, LLC
Creativity Performance in Healthy Subjects
Sleep and Creativity
Creativity is a complex neuro-psycho-philosophical phenomenon that is difficult to define. Neurocognitive models of creativity suggest that creativity is associated with the activity of a distributed, bilateral fronto-temporal…
- Trial name
- NCT04650438
- Testing
- Transcranial Magnetic Stimulation (TMS) over the left inferior frontal gyrus (IFG), Transcranial Magnetic Stimulation (TMS) over the left inferior parietal lobule (IPL)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Postpartum Anxiety, Postpartum Depression
Postpartum Screening for Anxiety and Comorbid Conditions
The goal of this project is to facilitate the design of individualized postpartum anxiety (PPA) screening strategies in British Columbia (BC), Canada.
- Conditions
- Postpartum Anxiety, Postpartum Depression, Postpartum Disorder, Postoperative Pain
- Trial name
- PPA (NCT06242717)
- Where
- Canada
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Sleep
Cannabis Association With Sleep Study
The purpose of this study is to learn more about cannabis use, sleep, and stress, and whether there is any relationship between the three.
- Trial name
- CaSS (NCT06982950)
- Testing
- Manipulation of Sleep Duration
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Health Literacy, Physical Activity
Education and Literacy for an Active Life (Educação e Literacia Para Uma Vida Ativa)
Health literacy is essential for children to develop healthy behaviors that persist into adulthood. It enables the access, understanding, evaluation, and application of health-related information, being a key component of health…
- Conditions
- Health Literacy, Physical Activity, Nutrition, Sedentary Behaviors
- Trial name
- ELeVA (NCT07100535)
- Testing
- Education and Literacy for an Active Life
- Where
- Portugal
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Lusofona University
Pregnancy Related, Sleep
Effect of Pregnant Pıllow on Sleep and Comfort
One of the most special life events of the fertile period is pregnancy. Pregnancy causes many physiological, metabolic, mental and social changes.
- Conditions
- Pregnancy Related, Sleep, Comfort
- Trial name
- NCT05790018
- Testing
- PREGNANT PILLOW
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Amasya University