Clinical trials: Sleep Apnea Syndromes, Obstructive
Obstructive Sleep Apnoea (OSA)
Effect of Bariatric Surgery on Obstructive Sleep Apnea in a Danish Cohort
Studies have shown high prevalence (60-94%) of obstructive sleep apnoea (OSA) among patients undergoing bariatric surgery. Fifteen studies are published investigating the effect of bariatric surgery on OSA.
- Trial name
- NCT02012868
- Testing
- bariatric surgery
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- University of Southern Denmark
Obstructive Sleep Apnea (OSA), Polysomnography
Multimodal Deep Learning Model for Predicting the Apnea-Hypopnea Index in Obstructive Sleep
This study aims to develop a multimodal deep learning model that integrates noninvasive signals to predict the severity of obstructive sleep apnea.
- Trial name
- NCT07447999
- Testing
- electronic stethoscope, fingertip pulse oximeter, pressure-sensing mattresses
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Fu Jen Catholic University
Sudden Hearing Loss, Obstructive Sleep Apnea
The Effect of PAP on ISSHL Comorbided With OSA
This clinical randomized controlled study is to explore the effect of positive airway pressure(PAP) on patients in Beijing Tsinghua Changgung Hospital diagnosed with both idiopathic sudden sensorineural hearing loss…
- Trial name
- NCT04192656
- Testing
- non-invasive positive airway pressure, Methylprednisolone Hemisuccinate, Ginaton
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Obstructive Sleep Apnea
Long-term Follow-up of Children With OSA Treated With AT
Objectives: To assess the cardiovascular outcomes of children with obstructive sleep apnoea (OSA) at a mean of 5 years after they had undergone adenotonsillectomy (AT), compared to OSA children who did not undergo AT, and normal…
- Trial name
- NCT04473066
- Testing
- Adenotonsillectomoy +/- turbinate reduction
- Where
- 2 sites in Hong Kong
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Pediatric Obstructive Sleep Apnea
Pediatric Obstructive Sleep Apnea Among Dental Interns in Egyptian Universities
Pediatric obstructive sleep apnea (OSA) is a common yet underdiagnosed sleep-related breathing disorder in children that may result in serious health and behavioral complications if left untreated.
- Trial name
- NCT07604831
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obstructive Sleep Apnea
The Impact of Daily Sinus Irrigation on Nasal Symptoms in Continuous Positive Airway Pressure (CPAP) Users - A Pilot Study
Continuous positive airway pressure (CPAP) is the most commonly used treatment for obstructive sleep apnea. Nasal symptoms such as dryness, itching and congestion are common in CPAP users.
- Trial name
- NCT01121445
- Testing
- NeilMed nose and sinus irrigation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Bridgeport Hospital
Obstructive Sleep Apnea
Use of Sleep Endoscopy to Predict Outcomes of Pediatric Adenotonsillectomy
Pediatric obstructive sleep apnea (OSA) is associated with heavy snoring and brief pauses in breathing during sleep. It affects at least 1-3% of the general pediatric population with greater prevalence among certain high risk…
- Trial name
- NCT02693977
- Testing
- Sleep Endoscopy
- Where
- United States
- Volunteers
- 347 people
- Sponsor
- Oregon Health and Science University
Polycystic Ovary Syndrome, Obstructive Sleep Apnea
Metabolic Study of Women With Polycystic Ovary Syndrome and Sleep Apnea
The purpose of this study is to look at the metabolic (use of energy) and hormonal features of sleep problems in women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT00696111
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Chicago
Obstructive Sleep Apnea
Precision Sleep Medicine
This retrospective observational study aims to characterize the prevalence and clinical features of obstructive sleep apnea (OSA) phenotypes and develop a rater-independent algorithm for automated OSA phenotyping, improving…
- Trial name
- NCT06903481
- Where
- 2 sites in Switzerland
- Volunteers
- 1,055 people
- Sponsor
- University Hospital, Basel, Switzerland
Sleep Apnea Syndrome
Efficacy of Telemonitoring on CPAP Treatment Compliance in Obstructive Sleep Apnea (OSA) Patients
The purpose of this study is to compare the effectiveness of telemonitoring versus standard follow-up on CPAP treatment compliance in Obstructive Sleep Apnea Syndrome (OSAS).
- Trial name
- NCT02517346
- Testing
- Standard follow-up, Telemonitoring
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Sleep Apnea Syndrome (OSAS), Orthognathic Surgical Procedures
Splintless Versus Conventional Maxillomandibular Advancement Surgery for Obstructive Sleep Apnea
The goal of this clinical trial is to find out whether using a splintless surgical approach improves the accuracy of maxillomandibular advancement (MMA) surgery for treating obstructive sleep apnea (OSA) in adults.
- Conditions
- Sleep Apnea Syndrome (OSAS), Orthognathic Surgical Procedures, Sleep Apnea - Obstructive
- Trial name
- SvCMAS (NCT07598461)
- Testing
- Splintless MMA surgery, Splint MMA surgery
- Where
- Netherlands
- Volunteers
- 66 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Obstructive Sleep Apnea
Accelerated Aging in Middle-Aged Men With Sleep-disordered Breathing.
Obstructive Sleep Apnea Syndrome (OSAS) regardless of any other associated risk factor can lead to accelerated aging. The study of aging-related Obstructive Sleep Apnea (OSA) is difficult because of associated risk factors…
- Trial name
- SAOS (NCT02876653)
- Testing
- Polysomnography , blood collection, bone densitometry and Functional respiratory explorations
- Where
- France
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obstructive Sleep Apnea
Efficacy and Stability of Dexmedetomidine Sedation Compared to Propofol Sedation in the Drug Induced Sleep Endoscopy
Obstructive Sleep Apnea Syndrome affect up 12% in adult population. It is associated with an increase rate of hypertension, metabolic syndrome, depression and adverse cardiovascular events.
- Trial name
- DISERT (NCT03892122)
- Testing
- Propofol Fresenius, Dexmedetomidine
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- Ospedale Monsignor R. Dimiccoli, Barletta
Otolaryngological Disease, Obstructive Sleep Apnea
Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Small Tonsils
The purpose of this study is to compare the effectiveness of a novel personalized surgical approach to the standard AT in children with small tonsils (ST).
- Trial name
- TOPS-ST (NCT06258837)
- Testing
- DISE-Directed Surgery, Adenotonsillectomy
- Where
- 2 sites in United States
- Volunteers
- 175 people
- Sponsor
- Oregon Health and Science University
Excessive Daytime Sleepiness, Obstructive Sleep Apnea
Solriamfetol's Effect on Cognitive Health in Apnea Participants During a Randomized Placebo-controlled Study
The purpose of study JZP110-405 is to determine whether solriamfetol is effective at improving cognitive function in participants with excessive daytime sleepiness (EDS) associated with obstructive sleep apnea (OSA) plus impaired…
- Conditions
- Excessive Daytime Sleepiness, Obstructive Sleep Apnea, Impaired Cognitive Function
- Trial name
- SHARP (NCT04789174)
- Testing
- Solriamfetol
- Where
- 28 sites in United States, Canada and 4 more
- Volunteers
- 59 people
- Sponsor
- Axsome Therapeutics, Inc.
Obstructive Sleep Apnea Syndrome
Cost-utility Study of Continuous Positive Airway Pressure Treatment in Obstructive Sleep Apnea Syndrome Patients
The purpose of this study is to estimate the cost-utility of continuous positive airway pressure (CPAP) therapy in obstructive sleep apnea (OSA) patients in Sao Paulo city, Brazil, after 3 years of treatment and to estimate the…
- Trial name
- NCT01590420
- Testing
- CPAP S8- Scape / Resmed
- Where
- Brazil
- Volunteers
- 1,000 people
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Syndrome of Obstructive Sleep Apnea and Hypopneas
Mandibular Advancement Devices Tali® in Patients With Syndrome of Obstructive Sleep Apnea and Hypopneas
The main objective is to evaluate middle term compliance (≥ 2 years) of the Mandibular Advancement Devices Tali® in patients with Syndrome of Obstructive Sleep Apnea and Hypopneas.
- Trial name
- NCT02878629
- Testing
- Mandibular Advancement Devices
- Where
- France
- Volunteers
- 254 people
- Sponsor
- ONIRIS
Insomnia, Obstructive Sleep Apnea
The Impact of CBT-i on CPAP Therapy Use and Drop Outs in OSAS Patients With Insomnia.
Patients follow the fully standard sleep test according to the normal procedure. This means that they undergo a polysomnography and fill in a questionnaire.
- Conditions
- Insomnia, Obstructive Sleep Apnea, Cognitive Behavioral Therapy, Continuous Positive Airway Pressure
- Trial name
- NCT04306835
- Testing
- Cognitive behavioural therapy for insomnia
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitair Ziekenhuis Brussel
Peripheral Artery Disease
Prevalence of Obstructive Sleep Apnea in Patients With Peripheral Arterial Occlusive Disease
Obstructive sleep apnea syndrome (OSAS) is characterized by partial (hypopnea) or complete (apnea) obstruction of the upper airways, leading to intermittent hypoxemia and sleep fragmentation.
- Trial name
- OSAPAD (NCT07283289)
- Where
- France
- Volunteers
- 295 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Chronic Pain, Obstructive Sleep Apnea
Clinical Outcomes of Continuous Positive Airway Pressure Treatment in People With Obstructive Sleep Apnea and Chronic Pain
The bidirectional link between sleep and pain is a widely accepted concept. While there has been much focus on this in recent years, studies investigating obstructive sleep apnoea (OSA) and chronic pain are still not very common…
- Trial name
- NCT06834724
- Testing
- Standard OSA care
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Vrije Universiteit Brussel
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