Clinical trials: Sleep Apnea Syndromes, Obstructive
Osa Syndrome
Evaluation of Prophylactic Heated Humidification on Obstructive Sleep Apnea (OSA) Patient Short Term Compliance to CPAP Therapy
To compare two different clinical strategies in order to evaluate the impact of prophylactic heated humidification on OSA patients' compliance to CPAP therapy.
- Trial name
- Humidifier (NCT04391699)
- Testing
- heated humidification
- Where
- France
- Sponsor
- ResMed
Obstructive Sleep Apnea
Prolonged Overnight Oximetry in Obstructive Sleep Apnoea
This study is looking at the way in which patients with obstructive sleep apnoea (OSA) are diagnosed. The investigators current practice is to offer patients who are referred to the sleep centre with possible sleep apnoea a…
- Trial name
- PROXIMO (NCT04287751)
- Testing
- CheckMeO2 Oximeter
- Volunteers
- 200 people
- Sponsor
- Somerset NHS Foundation Trust
Sleep Apnea Syndromes
Left Atrial Volume and Function Evaluation in Patients With Obstructive Sleep Apnea
The purpose of this study is to determine whether patients with obstructive sleep apnea have any changes in left atrial morphology and function evaluated by echocardiography three dimensional
- Trial name
- NCT00570115
- Where
- Brazil
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Sleep Apnea, Obstructive
Metabolic Effects of Metformin Therapy in Obstructive Sleep Apnea
The purpose of the study is to see if metformin improves metabolism in patients with obstructive sleep apnea (OSA) using positive airway pressure (PAP) therapy.
- Trial name
- MET-OSA (NCT04530747)
- Testing
- Metformin + PAP
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Pennington Biomedical Research Center
Obstructive Sleep Apnea
Real-time Attended Home-polysomnography Through Telematic Data Transmission
The purpose of this study is to develop an efficient home-based polysomnography device, which allows, through GPRS,continuous real-time monitoring from the sleep lab based in the hospital, in order to decrease the failure rate of…
- Trial name
- sleepbox (NCT01471626)
- Testing
- polysomnograph Dream and Sleep Box
- Where
- Belgium
- Volunteers
- 21 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Obstructive Sleep Apnea
DISE vs Muller's Maneuver in OSA Assessment
Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder caused by recurrent upper airway collapse during sleep.
- Trial name
- NCT07723417
- Testing
- Drug-Induced Sleep Endoscopy (DISE)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Obstructive Sleep Apnea
Treatment of Obstructive Sleep Apnea (OSA) With the da Vinci® SP™ Surgical System
It is a prospective, single center, single-arm clinical study to enroll a maximum of 25 subjects.
- Trial name
- NCT04795817
- Testing
- Transoral Robotic Surgery
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Intuitive Surgical
Obstructive Sleep Apnea of Adult
Acute and Long-term Effects of CPAP in OSA
Two-phase interventional non-inferiority trial (phase 1: at least 8 weeks of CPAP; phase 2: 2 weeks of CPAP withdrawal) including 32 patients with moderate to severe OSA to compare the physiological consequences of a short-term…
- Trial name
- NCT06277115
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- University of Zurich
OSAHS, Craniofacial Abnormalities
Upper-airway Changes After Bimaxillary Advancement in OSAHS
One of the most effective surgical treatments for obstructive sleep apnoea / hypopnoea syndrome (SAHS) with global impact on the upper-airway (UA) is the maxilla-mandibular advancement (MMA).
- Trial name
- OSAHS (NCT04301635)
- Testing
- Maxillo-mandibular Advancement + Counterclockwise rotation
- Where
- Spain
- Volunteers
- 38 people
- Sponsor
- Hospital de Cruces
Sleep Disordered Breathing (SDB), Sleep Apnea
Sleep Disordered Breathing and Multimorbidity: The Xiangya SDB Cohort Study
Sleep disordered breathing (SDB) is one of the most common sleep disorders, including obstructive sleep apnea (OSA), central sleep apnea (CSA), sleep-related hypoventilation, hypoxemia, etc., with OSA being the most prevalent.
- Conditions
- Sleep Disordered Breathing (SDB), Sleep Apnea, Cardiometabolic Diseases, Multimorbidity
- Trial name
- NCT06755840
- Where
- China
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Apnea, Sleep
Effects of CPAP on Cognitive Function, Neurocognitive Architecture and Function in Patients With OSA: The SMOSAT Trial
Multiple clinical studies have indicated that obstructive sleep apnea (OSA), the most common chronic sleep disorder, may affect neurocognitive function, and that treatment for continuous positive airway pressure (CPAP) has some…
- Trial name
- NCT02886156
- Testing
- CPAP, BSC
- Where
- China
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Obstructive Sleep Apnea
Change in C-reactive Protein (CRP) in Men and Women With Sleep Apnea After Continuous Positive Airway Pressure (CPAP)
C-reactive protein (CRP) is directly implicated in atherogenesis and associated cardiovascular morbidity in patients with obstructive sleep apnea (OSA).
- Trial name
- NCT01365832
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- Greece
- Volunteers
- 436 people
- Sponsor
- University of Crete
Asthma, Obstructive Sleep Apnea
Asthma and Obstructive Sleep Apnea (OSA)
Obstructive sleep apnea (OSA) is a common but under-diagnosed form of sleep disordered breathing (SDB). Asthma is a common disease with rising prevalence, which continues to pose significant morbidity and costs.
- Trial name
- NCT01026298
- Testing
- FDA-Approved Treatment
- Where
- United States
- Volunteers
- 744 people
- Sponsor
- University of Wisconsin, Madison
Sleep Apnea, Obstructive
Feasibility of Unattended Home Polysomnography and Comparison to In-laboratory Polysomnography in Pediatric Patients
The purpose of the study is: 1) To assess the feasibility of unmonitored polysomnography and 2) to compare apnea hypopnea index (AHI), average SPO2, and SPO2 nadir between unmonitored polysomnography and in-laboratory…
- Trial name
- NCT03473548
- Testing
- Portable sleep monitor, In-laboratory Polysomnography
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obstructive Sleep Apnea, Polysomnography
Screening Moderate to Severe Obstructive Sleep Apnea With Wearable Device
The goal of this study is to find the best method to use Wellue O2 ring to screen for moderate to severe obstructive sleep apnea.
- Conditions
- Obstructive Sleep Apnea, Polysomnography, Pulse Oximetry
- Trial name
- NCT06454318
- Testing
- Wellue O2 ring
- Where
- Thailand
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Thammasat University Hospital
Sleep Apnea, Obstructive
Influence of Different Methods of Measurement in the Accuracy of DES-OSA and P-SAP Scores
DES-OSA and P-SAP scores have been validated to detect OSA (Obstructive Sleep Apnea). One item of P-SAP and DES-OSA is the measurement of neck circumference.
- Trial name
- NCT03047421
- Testing
- Comparison of accuracy of DES-OSA and P-SAP scores
- Where
- Belgium
- Volunteers
- 1,682 people
- Sponsor
- Astes
Obstructive Sleep Apnea, Non-small Cell Lung Cancer
Obstructive Sleep Apnea Influences Efficacy of PD-1-Based Immunotherapy Against Non-Small Cell Lung Cancer
This prospective, observational cohort study aims to explore the influence of obstructive sleep apnea(OSA) on the efficacy of PD-1-based immunotherapy in patients with non-small cell lung cancer(NSCLC).
- Trial name
- NCT04743752
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Obstructive Sleep Apnea
Neck Liposuction for the Treatment of Obstructive Sleep Apnea
Liposuction, one of the most common cosmetic procedures performed in the United States, is a surgical technique used to reduce localized areas of excess subcutaneous fat.
- Trial name
- NCT01117974
- Testing
- liposuction of the neck
- Sponsor
- Northwestern University
Snoring, Obstructive Sleep Apnea
Safety, and Tolerability of the ZENS Device (PLUTO)
The primary objective of the PLUTO study is to evaluate the safety and tolerability of the ZENS transcutaneous nerve stimulator device in primary snorers and those with mild obstructive sleep apnea.
- Trial name
- NCT04063917
- Testing
- ZENS
- Where
- 2 sites in Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Zennea Technologies Inc.
Body Weight, Post-Op Complication
Development of Machine Learning Models for the Prediction of BMI and Complications After Bariatric Surgery (CABS-Study)
This Study aims to develop machine learning models with the ability to predict patients' BMI and complications after Bariatric Surgery (CABS-Score).
- Conditions
- Body Weight, Post-Op Complication, Anastomosis, Leaking, Hiatal Hernia
- Trial name
- NCT05710913
- Where
- Switzerland
- Volunteers
- 10,000 people
- Sponsor
- Dr. Med Anas Taha
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